The commissural interconnections of the inferior colliculus in the albino mouse.

abstract：:Reactive oxygen species (ROS) and intrinsic antioxidant defense systems play an important role in both physiological cell signaling processes and many pathological states, including neurodegenerative disorders and oxygen-toxicity. Here we report that short exposures to non-physiologic oxygen levels change the balance ...

journal_title：Brain research

authors： Bendix I,Weichelt U,Strasser K,Serdar M,Endesfelder S,von Haefen C,Heumann R,Ehrkamp A,Felderhoff-Mueser U,Sifringer M

更新日期：2012-11-12 00:00:00

abstract：:This study attempted to ascertain whether heatstroke-induced ischemia is associated with augmented striatal glutamate release and can be attenuated by NMDA receptor antagonists. Mean arterial pressure (MAP), striatal cerebral blood flow (CBF), striatal glutamate release and striatal neuronal damage score were assessed...

journal_title：Brain research

authors： Yang YL,Pan WH,Chiu TH,Lin MT

更新日期：1998-06-08 00:00:00

abstract：:Single unit discharges in the superior secondary gustatory nucleus of the carp, Cyprinus carpio L., were studied electrophysiologically in response to chemical stimulation of the external chemoreceptors of the facial skin surface. Of 36 gustatory neurons recorded, 80.6% were facilitated by taste stimuli and 19.4% were...

journal_title：Brain research

authors： Marui T

更新日期：1981-07-27 00:00:00

abstract：:The neuronal pathology caused by neonatal infection of rats with the PVC-211 murine leukemia virus (PVC-211 MuLV) and its underlying mechanisms are not well defined even though a loss of neurons and spongiform neurodegeneration has been reported to accompany the disease. Here we sought to identify sites of neurodegene...

journal_title：Brain research

authors： Xue QS,Yang C,Hoffman PM,Streit WJ

更新日期：2010-03-10 00:00:00

abstract：:Glioblastoma multiform is the most common malignant primary brain tumor in adults, but there remains no effective therapeutic approach. 2-methoxyestradiol (2-ME), which is a naturally occurring metabolite of 17beta-estradiol, was shown to enhance radiotherapeutic effect in certain tumors; however, whether 2-ME can als...

journal_title：Brain research

authors： Zou H,Zhao S,Zhang J,Lv G,Zhang X,Yu H,Wang H,Wang L

更新日期：2007-12-14 00:00:00

abstract：:The brain contains neurons which alter their firing rates when ambient glucose concentrations change. An ATP-sensitive K+ (Katp) channel on these neurons closes and increases cell firing when ATP is produced by intracellular glucose metabolism. Binding of the antidiabetic sulfonylurea drugs to a site linked to this ch...

journal_title：Brain research

authors： Levin BE,Brown KL,Dunn-Meynell AA

更新日期：1996-11-11 00:00:00

abstract：:Two high molecular weight surface glycoproteins of cerebellar cells which are selectively labeled by lactoperoxidase-catalyzed iodination of monolayer cultures from the developing mouse cerebellum, have been identified and partially characterised. Both molecules, called peak 2 and peak 3 proteins, were the major glyco...

journal_title：Brain research

authors： Goridis C,Hirsch M,Dossetto M,Baechler E

更新日期：1980-01-27 00:00:00

abstract：:Carnosine is a compound of naturally-occurring dipeptide that synthesized by the carnosine synthetase from beta-alanine and l-histidine. Recent reports claim that carnosine plays an important role in the control of epilepsy but its involvement in anticonvulsant functions remains unknown. In this study, we investigated...

journal_title：Brain research

authors： Kozan R,Sefil F,Bağirici F

更新日期：2008-11-06 00:00:00

abstract：:Intracellular assessments of the physiological actions of cannabinoid receptor agonists and antagonists on adult hippocampal CA1 pyramidal cells in the in vitro slice preparation were performed using current clamp and conventional sharp-electrode intracellular recording procedures. Several manipulations were performed...

journal_title：Brain research

authors： Kirby MT,Hampson RE,Deadwyler SA

更新日期：2000-04-28 00:00:00

abstract：:Small injections of two highly sensitive anterograde tracers, Phaseolus vulgaris-leucoagglutinin (PHA-L) and biocytin, into the striatum and the subthalamic nucleus of squirrel monkeys (Saimiri sciureus) have revealed a high degree of convergence of striatal and subthalamic fibers upon single pallidal cells. Both affe...

journal_title：Brain research

authors： Hazrati LN,Parent A

更新日期：1992-01-13 00:00:00

abstract：:The role of the substantia innominata (SI) in the generation of a behavior mediated by the prefrontal (PF) cortex was examined in two Japanese monkeys. PF neuronal activities related to a visual tracking task by wrist movement were recorded and neural responses to SI stimulation were analyzed. Sixty-six neurons showed...

journal_title：Brain research

authors： Funahashi S

更新日期：1983-10-16 00:00:00

abstract：:A study of brains of 16 dogs from one to 19 years of age showed a structure- and cell-type- specific pattern of tau protein phosphorylation at mAb Tau-1 site and the absence of phosphorylation at the mAb AT8 site. Strong immunolabeling with mAb Tau-1 of the mossy fibers and perikarya of neurons in sectors CA3 and CA4 ...

journal_title：Brain research

authors： Wegiel J,Wisniewski HM,Sołtysiak Z

更新日期：1998-08-17 00:00:00

abstract：:We have investigated the influence of central noradrenergic and dopaminergic systems on the susceptibility of rats to seizures in the kainic acid (KA)-model of epilepsy. In the dose range of 0.75 to 10 mg/kg s.c., KA dose-dependently induced characteristic behavioural changes. Partial depletion of noradrenaline (NA) a...

journal_title：Brain research

authors： Baran H,Hörtnagl H,Hornykiewicz O

更新日期：1989-08-28 00:00:00

abstract：:The retinoblastoma protein (pRb) is a key regulator of cell growth, differentiation and survival. pRb(-/-) mice show abnormal neuronal cell death in the developing brain. The function of pRb is regulated by its phosphorylation state. In this study, the phosphorylation of pRb during retinoic acid (RA)-induced neuronal ...

journal_title：Brain research

authors： Watanabe Y,Watanabe T,Kitagawa M,Taya Y,Nakayama K,Motoyama N

更新日期：1999-09-25 00:00:00

abstract：:Brief applications of high glycine concentrations to hippocampal slices have been shown to produce long-lasting changes in synaptic efficacy. In the present study, we show that glycine application transiently and reversibly increases the amplitude and prolongs the duration of synaptic potentials mediated by N-methyl-D...

journal_title：Brain research

authors： Shahi K,Baudry M

更新日期：1993-11-12 00:00:00

abstract：:This study compared the responsivity of alpha 2-adrenoceptors to agonists in normotensive (WKY) and genetically hypertensive (SH) rats. Clonidine produced a greater degree of analgesia in SH as compared to WKY rats. This analgesia was antagonized by yohimbine. Neither naphazoline nor 4-hydroxy-clonidine produced analg...

journal_title：Brain research

authors： Marwaha J

更新日期：1984-06-25 00:00:00

abstract：:The peak-to-peak amplitude of temporal middle latency response (MLR) of the guinea pig, evoked by a click in the contralateral ear, according to the recording side, is increased with the presence of continuous white noise (CWN) in the ipsilateral ear and this specialty is defined as the white noise enhancement (WNE). ...

journal_title：Brain research

authors： Goksoy C,Demirtas S,Ungan P

更新日期：2004-08-13 00:00:00

abstract：:Previous studies on the pathophysiology of white matter anoxic injury have revealed that the Na(+)-Ca2+ exchanger is an important mediator of Ca2+ overload. To date, however, the localization of this key Ca2+ transporter in myelinated axons has not been demonstrated. The present study uses immunofluorescence labeling ...

journal_title：Brain research

authors： Steffensen I,Waxman SG,Mills L,Stys PK

更新日期：1997-11-21 00:00:00

abstract：:Substance P(SP), the heptapeptide SP and the stable analogue (p-Glu5-MePhe8-MeGly9) SP (DiMe-C7) induce a Ca2+-dependent release of Met5-enkephalin (MET) from slices of periaqueductal gray matter (PAG) and striatum of rats. The MET release from striatal slices is greater than that from PAG slices because of the higher...

journal_title：Brain research

authors： Del Río J,Naranjo JR,Yang HY,Costa E

更新日期：1983-11-21 00:00:00

abstract：:Endogenous acetylcholine (ACh) release from rat striatal slices was measured by a chemiluminescent method. Several opiate agents were tested for their ability to modulate ACh release evoked by potassium ions (K+) or glutamic acid (GLU). Morphine, [D-Ala2,Gly(0l)5]-enkephalin (DAGO), [D-Ala2,D-Leu5]-enkephalin (DADLE) ...

journal_title：Brain research

authors： Arenas E,Alberch J,Sanchez Arroyos R,Marsal J

更新日期：1990-07-16 00:00:00

abstract：:Cultures of mouse spinal cord were used to visualize binding sites for [125I]angiotensin II (AII) by autoradiography. Visualization by light microscopy shows that neurones, but also glial cells possess angiotensin II binding sites which are located both on soma and processes. These findings open a new field of investi...

journal_title：Brain research

authors： Simonnet G,Legendre P,Laribi C,Allard M,Vincent JD

更新日期：1988-03-08 00:00:00

abstract：:The aim of this work was to investigate the modulation of the cardiovascular effects of neuropeptide Y (NPY) in the nucleus tractus solitarii (NTS) by angiotensin II (Ang II) and to determine the NPY receptor subtype involved in this modulation. Anesthesized Sprague-Dawley rats received microinjections in the NTS of A...

journal_title：Brain research

authors： Díaz-Cabiale Z,Fuxe K,Coveñas R,González-Barón S,Narváez JA

更新日期：2003-09-05 00:00:00

abstract：:High cell density, with attendant aggregation, selectively increases expression of substance P (SP) and choline acetyltransferase (ChAT) in virtually pure neonatal sympathetic neuronal cultures. To investigate the specific role of cell contact in selective transmitter expression, SP content and ChAT activity were exam...

journal_title：Brain research

authors： Adler JE,Black IB

更新日期：1986-12-01 00:00:00

abstract：:A detailed study of the distribution of neuropeptide Y (NPY) in the striatum of squirrel monkey (Saimiri sciureus) and cat was undertaken by means of indirect immunofluorescence and peroxidase-antiperoxidase (PAP) methods. In monkey, the NPY-immunoreactivity is homogeneously distributed along the entire extent of the ...

journal_title：Brain research

authors： Smith Y,Parent A

更新日期：1986-05-07 00:00:00

abstract：:Occipital cortex of 19-day-old fetal rats was dissociated and cultured in vitro for 2-5 weeks in horse serum supplemented Eagle's MEM. The outgrowing neurons rapidly formed a dense network which started to degenerate after 3 weeks in vitro. By means of electron microscopy the numerical development of 6 different categ...

journal_title：Brain research

authors： Romijn HJ,Mud MT,Habets AM,Wolters PS

更新日期：1981-07-01 00:00:00

abstract：:Individual neurons were recorded extracellularly in the nucleus accumbens (NAcc) of rats during cocaine self-administration sessions. NAcc neurons exhibited a variety of phasic changes in firing rate within the few seconds before and/or after cocaine self-infusion. Analysis of the topographical distribution of the pha...

journal_title：Brain research

authors： Uzwiak AJ,Guyette FX,West MO,Peoples LL

更新日期：1997-09-05 00:00:00

abstract：:Aging is accompanied by a general deterioration of fluid cognitive processes and a reduction in resting cerebral blood flow (CBF). While the two phenomena have been observed independently, it is uncertain whether individual differences in cerebral blood flow are reliably associated with cognitive functioning in older ...

journal_title：Brain research

authors： Heo S,Prakash RS,Voss MW,Erickson KI,Ouyang C,Sutton BP,Kramer AF

更新日期：2010-02-22 00:00:00

abstract：:Strong evidence obtained from in vivo and ex-vivo studies suggests the existence of interaction between dopaminergic and nitrergic systems. Some of the observations suggest a possible implication of nitric oxide (NO) in dopamine (DA) uptake mechanism. The present work investigated the interaction between both systems ...

journal_title：Brain research

authors： Salum C,Raisman-Vozari R,Michel PP,Gomes MZ,Mitkovski M,Ferrario JE,Ginestet L,Del Bel EA

更新日期：2008-03-10 00:00:00

abstract：:Pericyte coverage on the endothelial tubes leads to the formation of a mature and stable microvessel system, which is critical for brain repair after intracerebral hemorrhage (ICH). We report herein that thrombin promotes pericyte coverage by activating Tie2 and the downstream signaling pathway PI3K/Akt in a rat model...

journal_title：Brain research

authors： Hu E,Hu W,Yang A,Zhou H,Zhou J,Luo J,Wang Y,Tang T,Cui H

更新日期：2019-04-01 00:00:00

abstract：:Results from the application of a procedure that allows simultaneous estimation of the rates of glucose transport from blood and of glucose phosphorylation in discrete regions of the brain are given for groups of rats displaying chemically induced motor disturbances. The procedure is based on sequential injections of ...

journal_title：Brain research

authors： Cremer JE,Ray DE,Sarna GS,Cunningham VJ

更新日期：1981-09-28 00:00:00