A modification of the glyoxylic acid induced histofluorescence technique for demonstration of catecholamines and serotonin in tissues of Aplysia californica.

abstract：:The dorsolateral funiculus (DLF) spinal pathway has previously been identified as a major pathway involved in descending modulation of pain. While bilateral lesions of the DLF attenuated systemic morphine analgesia as measured by the tail-flick test, they failed to attenuate analgesia as measured by the formalin test....

journal_title：Brain research

authors： Ryan SM,Watkins LR,Mayer DJ,Maier SF

更新日期：1985-05-13 00:00:00

abstract：:To study the regulation of hypothalamic vasopressin (VP) and oxytocin (OT) gene expression in relation to the development of hypertension, levels of VP mRNA and OT mRNA were determined in spontaneously hypertensive rats (SHR). Differences in VP and OT mRNA content of the supraoptic nucleus (SON) and paraventricular nu...

journal_title：Brain research

authors： van Tol HH,van den Buuse M,de Jong W,Burbach JP

更新日期：1988-12-01 00:00:00

abstract：:The effects of the putative dopaminergic antagonist, haloperidol (0.01-10 mg/kg, i.v.), on cerebral glucose utilization in 43 anatomically discrete regions of the rat brain have been examined by the quantitative autoradiographic 2-deoxyglucose technique. Dose-dependent reductions in glucose utilization were observed i...

journal_title：Brain research

authors： McCulloch J,Savaki HE,Sokoloff L

更新日期：1982-07-08 00:00:00

abstract：:Our previous studies demonstrated that only a few days of housing in an enriched environment increases response strength and paired-pulse depression in the auditory cortex of awake and anesthetized rats [Engineer, N.D., Percaccio, C.R., Pandya, P.K., Moucha, R., Rathbun, D.L., Kilgard, M.P., 2004. Environmental enrich...

journal_title：Brain research

authors： Percaccio CR,Pruette AL,Mistry ST,Chen YH,Kilgard MP

更新日期：2007-10-12 00:00:00

abstract：:The hindpaw was partially denervated by the tibial nerve transection in adult rats. At post-transection intervals varying from 2 to 168 days, the hindpaw was stimulated bilaterally by subcutaneous injection of formalin. The excitability of dorsal horn neurons was expressed as the percentage ratio of the number of form...

journal_title：Brain research

authors： Sugimoto T,Ichikawa H,Mitani S,Hitsu A,Nakago T

更新日期：1994-04-11 00:00:00

abstract：:Fast axoplasmic transport was examined in experimental nerve ligation and adriamycin-induced neuronal perikaryon lesions. Animals were sacrificed at precisely 3 and 4 h following the injection of [3H]leucine. In single ligated nerves, the 3 and 4 h down-flow rates, which include the time for neuronal processing of lab...

journal_title：Brain research

authors： Sahenk Z,Mendell JR

更新日期：1979-07-27 00:00:00

abstract：:Interhemispheric connections were studied by injecting a mixture of horseradish peroxidase (HRP) and wheatgerm agglutinin conjugated with horseradish peroxidase (WGA-HRP) into multiple sites in dorsolateral occipital and parietal cortex of one cerebral hemisphere of three galagos (Galago crassicaudatus) and two owl mo...

journal_title：Brain research

authors： Beck PD,Kaas JH

更新日期：1994-07-18 00:00:00

abstract：:The disturbance of microcirculation following cerebral ischemia leads to an enlargement of cerebral infarct volume. Endogenous thrombin may play a role in this disturbance of microcirculation following cerebral ischemia. Therefore, the inhibition of thrombin may improve neurodegeneration and the accumulation of cerebr...

journal_title：Brain research

authors： Ohyama H,Hosomi N,Takahashi T,Mizushige K,Kohno M

更新日期：2001-06-01 00:00:00

abstract：:(1) Spontaneous barbiturate spindles were recorded from the primary and secondary somatosensory cortex. The recordings were concentrated to areas surrounding several reference loci. The recording sites producing the maximal response evoked by stimulation of an exposed nerve in a contralateral limb were used as referen...

journal_title：Brain research

authors： Ganes T

更新日期：1976-01-09 00:00:00

abstract：:The morphological features and distribution of luteinizing hormone-releasing hormone (LHRH)-immunoreactive cell bodies and fibers of the hypothalamic and the neighboring mesencephalic regions were studied in the normal newborn infant by immunohistochemistry. Within the hypothalamus, numerous LHRH-immunoreactive like (...

journal_title：Brain research

authors： Najimi M,Chigr F,Jordan D,Leduque P,Bloch B,Tommasi M,Rebaud P,Kopp N

更新日期：1990-05-21 00:00:00

abstract：:Single motor unit activity was recorded from human lower lip muscles while subjects maintained a firing rate of 20 ips using audio and visual feedback. Each motor unit was classified as belonging to one of three muscles, orbicularis oris inferior (OOI), mentalis (MENT), or depressor labii inferior (DLI). Reflex respon...

journal_title：Brain research

authors： McClean MD,Smith A

更新日期：1982-11-11 00:00:00

abstract：:Vanilloid (capsaicin) receptors were visualized by [3H]resiniferatoxin (RTX) autoradiography in the brain of newborn as well as adult (both control and colchicine-treated) rats. Specific labelling was seen in the brain stem only, in the nucleus of the solitary tract extending into the area postrema and the spinal sens...

journal_title：Brain research

authors： Szallasi A,Nilsson S,Farkas-Szallasi T,Blumberg PM,Hökfelt T,Lundberg JM

更新日期：1995-12-12 00:00:00

abstract：:The recently developed technique of in vivo dialysis has permitted us to make direct measurements of serotonin release in a specific region of the spinal cord and to relate this to changes in blood pressure elicited by chemical stimulation of the brainstem. In the present experiments we have shown that chemical stimul...

journal_title：Brain research

authors： Pilowsky PM,Kapoor V,Minson JB,West MJ,Chalmers JP

更新日期：1986-02-26 00:00:00

abstract：:A novel RNA-mediated disease mechanism has emerged from studies on dominantly inherited neurological disorders caused by unstable microsatellite expansions in non-coding regions of the genome. These non-coding tandem repeat expansions trigger the production of unusual RNAs that gain a toxic function, which involves th...

journal_title：Brain research

authors： Mohan A,Goodwin M,Swanson MS

更新日期：2014-10-10 00:00:00

abstract：:We have previously reported that intracerebroventricular injection of prostaglandin E2 (PGE2) induces hyperthermia possibly through EP1 receptors in the rat. In the present study, to determine the sites in the brain where PGE2 induces hyperthermia through EP1 receptors, we microinjected an EP1 receptor agonist, 17-phe...

journal_title：Brain research

authors： Oka K,Oka T,Hori T

更新日期：1997-08-29 00:00:00

abstract：:Earlier studies showed that pretreatment (3 and 6 h) of rats with the glucocorticoid hormone, dexamethasone, potentiated the drinking response to either central or peripheral administration of angiotensin II (AII). In the present study the specificity and mechanisms of this potentiation were examined. Intraperitoneal ...

journal_title：Brain research

authors： Sumners C,Gault TR,Fregly MJ

更新日期：1991-06-28 00:00:00

abstract：:Ischemic-reperfusion injury in humans occurs in conditions such as stroke, cardiac arrest, subarachnoid hemorrhage or head trauma. Maximal tissue damage is observed during reperfusion, which is primarily attributed to oxidative injury resulting from production of oxygen free radicals. One of the major consequences of ...

journal_title：Brain research

authors： Panigrahi M,Sadguna Y,Shivakumar BR,Kolluri SV,Roy S,Packer L,Ravindranath V

更新日期：1996-04-22 00:00:00

abstract：:Spontaneous alternation which is disrupted by lesion of septal dopaminergic (DA) afferents was chosen as a behavioral marker for the study of functional interactions between DA and noradrenergic (NA) innervation of the lateral septum. Three groups of rats were studied: a solvent group which received only vehicle injec...

journal_title：Brain research

authors： Taghzouti K,Le Moal M,Simon H

更新日期：1991-06-21 00:00:00

abstract：:The present electric shock (ES) schedule followed in these experiments produced different functional changes in endogenous putative opioid agonist- and antagonist-type receptors, depending on the type of receptor: the amount of antagonist binding was increased by ES application, while the amount of agonist binding was...

journal_title：Brain research

authors： Nabeshima T,Matsuno K,Kameyama T

更新日期：1985-09-16 00:00:00

abstract：:Microencephalic rats induced by methylazoxymethanol (MAM) were observed to have notable hyperactivity compared to control rats, as measured by several behavioral parameters in an automated field apparatus. Acute injection of the stimulant drug, methamphetamine (MAP), produced an increase in the incidence of locomotion...

journal_title：Brain research

authors： Watanabe M,Shimizu K,Kodama Y,Takishima K,Mamiya G,Ichinowatari N

更新日期：1995-01-23 00:00:00

abstract：:Male guinea pigs were given 3 tests for sexual behavior. Animals that never ejaculated were classified as low activity (LA), animals that ejaculated on one test were classified as medium activity (MA), and animals that ejaculated on two or more tests were classified as high activity (HA). Subsequently, animals from ea...

journal_title：Brain research

authors： Harding CF,Feder HH

更新日期：1976-03-19 00:00:00

abstract：:Activities of individual, force-sensitive mechanoreceptors (funnel canal organs) of the terminal segment (dactyl) of the crab leg have been recorded in freely moving animals. During the stance phase of walking receptors discharge in regular bursts that are closely correlated with activity of the opener muscle of the p...

journal_title：Brain research

authors： Zill SN,Libersat F,Clarac F

更新日期：1985-06-17 00:00:00

abstract：:Glutamate N-methyl-D-aspartate receptors (NMDARs) in the medial prefrontal cortex (mPFC) and hippocampus may play an integral role in complex cognitive and social deficits associated with a number of psychiatric illnesses including autism, mood disorders, and schizophrenia. We used localized infusions of adeno-associa...

journal_title：Brain research

authors： Finlay JM,Dunham GA,Isherwood AM,Newton CJ,Nguyen TV,Reppar PC,Snitkovski I,Paschall SA,Greene RW

更新日期：2015-03-10 00:00:00

abstract：:Previous immunocytochemical, physiological, and molecular studies have reported that the Syrian hamster lacks a shortwave-sensitive (S) cone photopigment but retains circadian responses to ultraviolet (UV) light. Using opsin antibodies and a sensitive detection protocol, we here show that S opsin immunoreactivity colo...

journal_title：Brain research

authors： Glösmann M,Ahnelt PK

更新日期：2002-03-01 00:00:00

abstract：:The hypothesis that inhibition of nitric oxide (NO) synthase with subsequent decrease in the production of NO might attenuate the development of kappa-opiate tolerance was examined. Concurrent treatment of NO synthase inhibitor, NG-monomethyl-L-arginine (L-NMMA) (2-8 mg/kg, i.p.) along with U-50,488H (25 mg/kg, i.p.) ...

journal_title：Brain research

authors： Thorat SN,Reddy PL,Bhargava HN

更新日期：1993-09-03 00:00:00

abstract：:Six experimental and 3 unoperated cats were trained with a go, no-go shock avoidance procedure to discriminate increases from decreases in the rate of presentation of all auditory cortex between the suprasylvian sulcus and rhinal fissure while 3 cats had bilateral auditory cortex lesions plus ablation of the cortex of...

journal_title：Brain research

authors： Cranford JL,Igarashi M,Stramler JH

更新日期：1976-10-29 00:00:00

abstract：:The postnatal development of the distribution of 3 different ionic channel proteins in rat brain was studied using light microscopic autoradiography. [3H]Ethylenediaminetetrodotoxin, [125I]apamin and (-)-[3H]desmethoxyverapamil were used to label one class of voltage-dependent Na+ channel proteins, one class of Ca2+-d...

journal_title：Brain research

authors： Mourre C,Cervera P,Lazdunski M

更新日期：1987-08-04 00:00:00

abstract：:The purpose of this study was to investigate the cannabinoid and opioid mediated regulation on the effects of central Delta(9)-tetrahydrocannabinol (Delta(9)-THC) administration on hypothalamus-pituitary-adrenal (HPA) axis activity in the male rat. Intracerebroventricular (i.c.v.) administration of delta(9)-THC (25, 5...

journal_title：Brain research

authors： Manzanares J,Corchero J,Fuentes JA

更新日期：1999-08-21 00:00:00

abstract：:Perfusion of hippocampal slices with normoxic medium containing no added sodium resulted in a rapid loss of the CA1 population spike, with only 35 +/- 10% (S.E.M.) (P < 0.001) recovery after a 15 min exposure. This injury was prevented by the non-competitive N-methyl-D-aspartate (NMDA) antagonist MK-801 (93 +/- 4% rec...

journal_title：Brain research

authors： Parsons JE,Wallis RA,Panizzon KL,Wasterlain CG

更新日期：1992-11-06 00:00:00

abstract：:Dexmedetomidine (Dex) has the neuroprotective effect on cerebral ischemia-reperfusion injury (CIRI). But the mechanism is not yet clear. In this study, we established a model of middle cerebral artery occlusion (MCAO) and treated primary cortical neurons with oxygen glucose deprivation (OGD), followed by Dex treatment...

journal_title：Brain research

authors： Liu C,Fu Q,Mu R,Wang F,Zhou C,Zhang L,Yu B,Zhang Y,Fang T,Tian F

更新日期：2018-12-15 00:00:00