Protein kinase C gamma-like immunoreactivity of trigeminothalamic neurons in the medullary dorsal horn of the rat.

abstract：:The current study explored the effects of prolonged antidepressant treatment on mRNA levels of two nuclear receptors in specific brain regions of an animal model of depression, the Wistar-Kyoto (WKY) rat. Both nuclear receptors have been implicated in the development or treatment of depression. The expression of nucle...

journal_title：Brain research

authors： Schaffer DJ,Tunc-Ozcan E,Shukla PK,Volenec A,Redei EE

更新日期：2010-11-29 00:00:00

abstract：:Fluoro-Gold has been used previously to identify those trigeminal ganglion cells that innervate the central cornea. To examine the effects of Fluoro-Gold treatment on infection and spread of HSV in vivo, we measured the number of plaque forming units recovered from trigeminal ganglia 3 or 5 days after corneal scratch ...

journal_title：Brain research

authors： LaVail JH,Carter SR,Topp KS

更新日期：1993-10-15 00:00:00

abstract：:Acetylcholinesterase (AchE) is an important peripheral membrane-bound enzyme, crucial for cholinergic neurotransmission. Changes in AchE activity, kinetic and thermotropic properties were studied in hepatic encephalopathy (HE) associated with acute liver failure induced experimentally by the administration of the hepa...

journal_title：Brain research

authors： Swapna I,SathyaSaikumar KV,Murthy ChR,Gupta AD,Senthilkumaran B

更新日期：2007-06-11 00:00:00

abstract：:The neuropathological consequences of acute exposure to the neurotoxicants ammonia and octanoic acid were investigated with the isolated, perfused canine brain preparation. After 1 h of combined hyperammonemia and octanoic acidemia, ultrastructural changes were apparent in all brain regions examined. The cell bodies o...

journal_title：Brain research

authors： Drewes LR,Leino RL

更新日期：1985-08-12 00:00:00

abstract：:Sodium and potassium currents in the node of Ranvier decrease exponentially with time during long lasting voltage clamp experiments. This decline is strongly dependent on temperature (Q10 approximately 3). Thiamine and, particularly, its diand triphosphoric acid esters are shown to prevent this exponential decline of ...

journal_title：Brain research

authors： Fox JM,Duppel W

更新日期：1975-05-23 00:00:00

abstract：:Extracellular amino acids were followed in the hippocampus during sustained seizures induced by systemic administration of kainic acid (KA) or bicuculline (BC). KA epilepsy was associated with marked increases in phosphoethanolamine (PEA) and taurine. Alanine and ethanolamine were moderately raised while other amino a...

journal_title：Brain research

authors： Lehmann A,Hagberg H,Jacobson I,Hamberger A

更新日期：1985-12-16 00:00:00

abstract：:Calcium/calmodulin-dependent protein kinase II (kinase II) and protein phosphatase 2B (calcineurin) immunoreactivity in the rat hippocampus was studied 100 days after ischemic damage to hippocampal CA1 pyramidal neurons. One-hundred days after ischemia, only a few CA1 pyramidal neurons survived and they exhibited enha...

journal_title：Brain research

authors： Onodera H,Yamasaki Y,Kogure K,Miyamoto E

更新日期：1995-06-26 00:00:00

abstract：:Dopamine neurons are overstimulated by drugs of abuse and suffer molecular alterations that lead to addiction behavior. Nurr1 is a transcription factor crucial for dopamine neurons survival and dopamine production, activating the transcription of key genes like tyrosine hydroxylase (TH). Interestingly, nuclear factor-...

journal_title：Brain research

authors： Arredondo C,González M,Andrés ME,Gysling K

更新日期：2016-12-01 00:00:00

abstract：:Unilateral injections of 6-hydroxydopamine into the substantia nigra in the rat significantly attenuated cortical spreading depression (CSD)-induced eating from the hemisphere ipsilateral but not contralateral to the lesion. The lateralized decrease in elicited feeding was correlated with postlesion body weight loss, ...

journal_title：Brain research

authors： Siegfried B,Hefti F,Lichtensteiger W,Huston JP

更新日期：1979-01-12 00:00:00

abstract：:Adenosine and its agonists exert a depressant effect on neuronal activity by interacting with the adenosine A1 receptor. There is now also evidence for electrophysiological effects mediated by adenosine receptors other than the A1 type, possibly A2 receptors. A1 and A2 receptor-induced changes in the electrical proper...

journal_title：Brain research

authors： Ameri A,Jurna I

更新日期：1991-04-12 00:00:00

abstract：:In the cat, cells of the superior colliculus (SC) and the tectofugal pathways of the visual system are highly selective for the direction of a moving visual stimulus. Deep layer units of SC in addition respond to auditory and somatosensory stimuli, but the proportion of such non-visual cells is usually found to be muc...

journal_title：Brain research

authors： Rauschecker JP,Harris LR

更新日期：1989-06-19 00:00:00

abstract：:The effects of diclofenac, a nonsteroidal anti-inflammatory drug (NSAID), on the fast tetrodotoxin-sensitive (TTX-S) and the slow tetrodotoxin-resistant (TTX-R) sodium currents in rat dorsal root ganglion neurons were investigated using the whole-cell patch-clamp method. Diclofenac suppressed both sodium currents in a...

journal_title：Brain research

authors： Lee HM,Kim HI,Shin YK,Lee CS,Park M,Song JH

更新日期：2003-11-28 00:00:00

abstract：:Molecular mechanism underlying ischemic stroke remains poorly understood. We previously reported glucose 6-phosphate dehydrogenase (G6PD) activity in pentose phosphate pathway (PPP) is activated via heat shock protein 27 (HSP27) phosphorylation at serine 85 (S85) by ataxia telangiectasia mutated (ATM) kinase during ce...

journal_title：Brain research

authors： Yamamoto Y,Hosoda K,Imahori T,Tanaka J,Matsuo K,Nakai T,Irino Y,Shinohara M,Sato N,Sasayama T,Tanaka K,Nagashima H,Kohta M,Kohmura E

更新日期：2018-05-15 00:00:00

abstract：:Muscle spindle activity has been shown to decrease in the sustained contracting muscle. The effect has been assumed to result from a declining fusimotor drive. Since accumulation of metabolites including H(+), lactate and CO(2) might also affect the receptor in the fatiguing muscle, the impulse activity of muscle spin...

journal_title：Brain research

authors： Fischer M,Schäfer SS

更新日期：2005-05-10 00:00:00

abstract：:In the inferior colliculus of the mouse, 4 cell types project across the collicular commissure: small to medium sized spiny cells, small to medium sized spineless cells, medium sized sparsely spinous neurons and large cells. The axons of large cells give rise to a great number of ipsi- and contralateral collaterals te...

journal_title：Brain research

authors： González Hernández TH,Meyer G,Ferres-Torres R

更新日期：1986-03-19 00:00:00

abstract：:Serum-free aggregating cell cultures of fetal rat telencephalon grown in the presence of 3 ng/ml (5 X 10(-10) M) epidermal growth factor (EGF) until day 12 showed 2- to 3-fold increased activities in the two glial enzymes, glutamine synthetase (GLU-S) and 2',3'-cyclic nucleotide 3'-phosphohydrolase (CNPase). This effe...

journal_title：Brain research

authors： Honegger P,Guentert-Lauber B

更新日期：1983-12-01 00:00:00

abstract：:Stimuli such as noise or hypoxia can induce a release of ATP into the cochlear fluid spaces. At nanomolar concentrations, ATP affects neurotransmission and electrochemical regulation of sound transduction. At higher concentrations, ATP may exert cytotoxicity acting on specific P2X(7) receptor subunits, thus contributi...

journal_title：Brain research

authors： Vlajkovic SM,Vinayagamoorthy A,Thorne PR,Robson SC,Wang CJ,Housley GD

更新日期：2006-08-09 00:00:00

abstract：:The N400 is an event-related potential (ERP) component that is elicited by semantically meaningful stimuli; one of its defining characteristics is that it is amplified for sentence completions that are semantically unexpected or incongruous with the preceding context. Some prior reports using visual sentence reading p...

journal_title：Brain research

authors： Dien J,Michelson CA,Franklin MS

更新日期：2010-10-08 00:00:00

abstract：:We previously observed that substance P (SP) levels in the rat superior cervical ganglion (SCG) rise sharply when the ganglion is maintained in vitro. To define the cellular localization of SP, sections of cultured SCG were stained for the possible dual presence of SP and tyrosine hydroxylase (TOH). Immunoreactivity t...

journal_title：Brain research

authors： Bohn MC,Kessler JA,Adler JE,Markey K,Goldstein M,Black IB

更新日期：1984-04-30 00:00:00

abstract：:Previous studies have suggested that substance P (SP) plays a critical role in the development of brain oedema and functional deficits following traumatic brain injury and that SP receptor antagonism may improve outcome. No studies have described such a role in ischemic stroke. The present study characterized the effe...

journal_title：Brain research

authors： Turner RJ,Helps SC,Thornton E,Vink R

更新日期：2011-06-01 00:00:00

abstract：:Circling training during rat striatum postnatal critical period (PN30 to 37 days) induces a life-lasting co-reduction of muscarinic acetylcholine receptors (mAChR) and dopamine D2 receptors (D2R) binding. Here, we evaluated the expression of D1R and D2R under similar experimental conditions. Trained rats showed a decr...

journal_title：Brain research

authors： Soiza-Reilly M,Fossati M,Ibarra GR,Azcurra JM

更新日期：2004-04-09 00:00:00

abstract：:Active substance P binding sites were solubilized from rat brain membranes by treatment with 0.125% sodium glycodeoxycholate and 1 M NaCl. About 50% of the binding activity in membrane-bound binding sites was recovered in the solubilized fraction after centrifugation at 105,000 g for 1 h. [3H]Substance P absorbed exte...

journal_title：Brain research

authors： Maruyama M

更新日期：1986-04-02 00:00:00

abstract：:The nucleus of the solitary tract (NTS) is a critical structure involved in coordinating autonomic and visceral activities. Previous independent studies have demonstrated efferent projections from the NTS to the nucleus paragigantocellularis (PGi) and the central nucleus of the amygdala (CNA) in rat brain. To further ...

journal_title：Brain research

authors： Reyes BA,Van Bockstaele EJ

更新日期：2006-10-30 00:00:00

abstract：:We previously reported that angiotensin II type 2 (AT(2)) receptor signaling prevents neural damage and cognitive impairment after focal cerebral ischemia. We investigated the possible roles of the AT(2) receptor in the sex difference, focusing on cognitive function and ischemic brain damage using AT(2) receptor-defic...

journal_title：Brain research

authors： Sakata A,Mogi M,Iwanami J,Tsukuda K,Min LJ,Fujita T,Iwai M,Ito M,Horiuchi M

更新日期：2009-12-01 00:00:00

abstract：:Rapid eye movement (REM) sleep is hypothesized to result from the activity of REM sleep-generating and REM sleep-inhibiting neurons. The serotoninergic (5-HT) neurons of the dorsal raphe nucleus (DRN) represents one such population of REM-sleep inhibiting neurons since they are silent during REM sleep. Consistent with...

journal_title：Brain research

authors： Blanco-Centurion CA,Salin-Pascual RJ

更新日期：2001-12-27 00:00:00

abstract：:The vascular changes in the hippocampus and neocortex during kainic acid-induced seizures were investigated in control rats and in rats with chronic, bilateral, cervical sympathectomy. Seizures were induced in unanesthetized, spontaneously breathing rats. The increase in blood flow in the hippocampus of the sympathect...

journal_title：Brain research

authors： Rigaud AS,Pinard E,Borredon J,Seylaz J

更新日期：1990-11-05 00:00:00

abstract：:Inhibitory GABAergic synaptic transmission in the mammalian hippocampus depends upon a hyperpolarized reversal potential for Cl(-) (ECl). To examine the regulation of ECl hyperpolarization we cultured hippocampal neurons for two weeks in either a low- or a high-concentration of KCl (2.6 or 18.7 mM, respectively). Neur...

journal_title：Brain research

authors： Balena T,Acton BA,Koval D,Woodin MA

更新日期：2008-04-18 00:00:00

abstract：:To examine the effect of short-term and long-term adrenalectomy (ADX) on the glucocorticoid receptor (GR) expression, we performed an immunohistochemical study on the rat forebrain. One day after ADX, the GR-immunoreactivity significantly decreased or disappeared in most forebrain structures, while relatively strong G...

journal_title：Brain research

authors： Visser DT,Hu Z,Pasterkamp RJ,Morimoto M,Kawata M

更新日期：1996-08-12 00:00:00

abstract：:Threatening stimuli are thought to bias spatial attention toward the location from which the threat is presented. Although this effect is well-established in the visual domain, little is known regarding whether tactile attention is similarly affected by threatening pictures. We hypothesised that tactile attention migh...

journal_title：Brain research

authors： Van Damme S,Gallace A,Spence C,Crombez G,Moseley GL

更新日期：2009-02-09 00:00:00

abstract：:Cell transplantation using ventral mesencephalic tissue is an experimental approach to treat Parkinson's disease. This approach is limited by poor survival of the transplants and the high number of dopaminergic neurons needed for grafting. Increasing the yield of dopaminergic neurons in donor tissue is of great import...

journal_title：Brain research

authors： Seiler S,Di Santo S,Sahli S,Andereggen L,Widmer HR

更新日期：2017-08-01 00:00:00