Synergistic interactions of endogenous opioids and cannabinoid systems.

abstract：:The blood-brain interface in elasmobranchs was examined using physiological and anatomical techniques. Electrolyte analyses of plasma and cerebrospinal fluid (CSF) in control fish and in fish with elevated plasma cation concentration (Ca, Mg or K) demonstrated homeostasis of CSF calcium and magnesium concentrations in...

journal_title：Brain research

authors： Bundgaard M,Cserr H

更新日期：1981-12-07 00:00:00

abstract：:Transgenic mice expressing human APPswe and PS1-A264E mutations mimic certain neuropathological features of Alzheimer's disease (AD). These mice have elevated levels of the highly fibrillogenic amyloid beta1-42 peptide (Abeta42) and develop amyloid plaques around the age of 9 months. Our aim was to find whether these ...

journal_title：Brain research

authors： Wang J,Ikonen S,Gurevicius K,van Groen T,Tanila H

更新日期：2002-07-12 00:00:00

abstract：:'Spontaneous' and visually evoked action potentials were recorded from single neurons in cytoarchitectonic area 17 (striate cortex, area V1) of anaesthetized and immobilized cats, prior to, during and after brief reversible inactivation of the ipsilateral postero-temporal visual (PTV) cortex (presumed homologue of pri...

journal_title：Brain research

authors： Huang JY,Wang C,Dreher B

更新日期：2007-03-23 00:00:00

abstract：:We identified the burst and single-spiking cells, and the repetitive bursting cells in layers III and V of the cat sensorimotor cortex with intracellular recording and staining techniques. Both types of the bursting cells were found in 22.7% of the recorded layer V neurons and in 23.1% of the recorded neurons in layer...

journal_title：Brain research

authors： Nishimura Y,Kitagawa H,Saitoh K,Asahi M,Itoh K,Yoshioka K,Asahara T,Tanaka T,Yamamoto T

更新日期：1996-07-15 00:00:00

abstract：:To determine whether oculomotor internuclear neurons (INOs) establish unilateral or bilateral connections with the abducens nucleus (nVI), horseradish peroxidase (HRP) and either DAPI or Nuclear Yellow (NY) were injected into nVI and the oculomotor complex (nIII) examined for retrogradely labeled cells. Such injection...

journal_title：Brain research

authors： Maciewicz R,Phipps BS

更新日期：1983-02-28 00:00:00

abstract：:There is increasing evidence that traumatic brain injury (TBI) induces hypofunction of the striatal dopaminergic system, the mechanisms of which are unknown. In this study, we analyzed the activity of striatal tyrosine hydroxylase (TH) in rats at 1 day, 1 week, and 4 weeks after TBI using the controlled cortical impac...

journal_title：Brain research

authors： Shin SS,Bray ER,Zhang CQ,Dixon CE

更新日期：2011-01-19 00:00:00

abstract：:The effects of the serotonin precursor 5-HTP, were determined in a behavioral DNIC paradigm (increase in vocalization threshold after intraperitoneal injection of the algogenic agent, phenylbenzoquinone). This counter-irritation phenomenon was strongly potentiated by 5-HTP, such potentiation being blocked by the 5-HT ...

journal_title：Brain research

authors： Kraus E,Besson JM,Le Bars D

更新日期：1982-01-14 00:00:00

abstract：:The injured spinal cord does not heal properly. In contrast, tissue repair and functional recovery occur after skin or muscle injuries. The reason for this dichotomy in wound repair is unclear but inflammation, and specifically macrophage activation, likely plays a key role. Macrophages have the ability to promote the...

journal_title：Brain research

authors： Gensel JC,Zhang B

更新日期：2015-09-04 00:00:00

abstract：:The analgesia induced by 30-s footshock (1 mA) is enhanced and attenuated by decreasing and increasing the extraneuronal availability of serotonin (5-HT), respectively. In the present work we have shown the effect to be mediated by spinal 5-HT systems as the response was increased by depletion of spinal but not brain ...

journal_title：Brain research

authors： Hutson PH,Tricklebank MD,Curzon G

更新日期：1982-04-15 00:00:00

abstract：:Neurotensin-producing perikarya and fibers have been identified in the ventral tegmental area of the rat, and recent microinjection studies indicate that neurotensin may function in the ventral tegmental area to regulate body temperature. In this study, the hypothermic response produced by intraventral tegmental injec...

journal_title：Brain research

authors： Kalivas PW,Nemeroff CB,Miller JS,Prange AJ Jr

更新日期：1985-02-11 00:00:00

abstract：:Neurofilaments were assembled in vitro from the high speed supernatant of mammalian CNS homogenate in a disassembly buffer containing 4-morpholine-ethane sulfonic acid, MgCl2 and EGTA at 4 degrees C in the presence of 4 M glycerol. The assembled neurofilaments were depolymerized by dialysis against the disassembly buf...

journal_title：Brain research

authors： Iqbal K,Grundke-Iqbal I,Merz PA,Wisniewski HM,Zaidi T

更新日期：1987-07-01 00:00:00

abstract：:Previous research has demonstrated that in the Siberian hamster, both photoperiod and estrous cyclicity alter the profile of noradrenergic activity with the paraventricular nucleus of the hypothalamus (PVN), and that noradrenergic activity is correlated with changes in circulating levels of prolactin. Work from our la...

journal_title：Brain research

authors： Dodge JC,Badura LL

更新日期：2004-08-06 00:00:00

abstract：:The Harderian gland of birds, a major lacrimal gland, contains a large population of lymphoid cells that produce IgA, a significant component of tears. Using histochemical techniques, we have examined the innervation of the gland. There was an extensive acetylcholine-esterase positive fiber network throughout the glan...

journal_title：Brain research

authors： Walcott B,McLean JR

更新日期：1985-02-25 00:00:00

abstract：:We studied the effect of the cortical projection from the basal forebrain on the cerebral cortical metabolism using positron emission tomography (PET) with [(18)F] fluorodeoxyglucose. Unilateral damage of the nucleus basalis magnocellularis (NBM) did not cause a permanent reduction of cortical metabolism: recovery was...

journal_title：Brain research

authors： Katsumi Y,Hanakawa T,Fukuyama H,Hayashi T,Nagahama Y,Yamauchi H,Ouchi Y,Tsukada H,Shibasaki H

更新日期：1999-08-07 00:00:00

abstract：:In anesthetized cats, medial gastrocnemius motor units (MUs) were electrically stimulated via their ventral-root axons with independent random patterns. Muscle tension and homonymous alpha-motoneuron (alpha-MN) membrane potential fluctuations in response to these stimuli were recorded simultaneously. Cross-correlating...

journal_title：Brain research

authors： Koehler W,Hamm TM,Enoka RM,Stuart DG,Windhorst U

更新日期：1985-09-23 00:00:00

abstract：:The formation of reactive oxygen species (ROS) has been suggested to be associated with excitotoxicity but the involvement of cytoplasmic enzymes in ROS formation is not clearly known. In the present study, we examined the role of xanthine oxidase (XO), nitric oxide synthase (NOS) and phospholipase A(2) (PLA(2)) in gl...

journal_title：Brain research

authors： Sanganahalli BG,Joshi PG,Joshi NB

更新日期：2005-03-10 00:00:00

abstract：:Alzheimer's disease (AD) classically presents with gray matter atrophy, as well as feature significant white matter abnormalities. Previous evidence indicates the overall burden of these pathological changes continues to advance as the disease progresses. The aim of this study was to investigate whether pathological a...

journal_title：Brain research

authors： Kitamura S,Kiuchi K,Taoka T,Hashimoto K,Ueda S,Yasuno F,Morikawa M,Kichikawa K,Kishimoto T

更新日期：2013-06-17 00:00:00

abstract：:Transient ischemia increases tyrosine phosphorylation of N-methyl-D-aspartate (NMDA) receptor. Several tyrosine kinases are involved in this process. In this study, effect of ischemia and reperfusion (I/R) on tyrosine phosphorylation of NMDA receptor subunit 2A (NR2A) and the interaction of two tyrosine kinases, Src a...

journal_title：Brain research

authors： Liu Y,Zhang G,Gao C,Hou X

更新日期：2001-08-03 00:00:00

abstract：:Corticotropin-releasing factor (CRF) in the brain plays an important role in regulations of physiological and behavioral processes, yet CRF distribution in tree shrew brain has not been thoroughly and systematically reported. Here we examined the distribution of CRF immunoreactivity in the brain of tree shrews (Tupaia...

journal_title：Brain research

authors： Shu YM,Ni RJ,Sun YJ,Fang H,Zhou JN

更新日期：2015-08-27 00:00:00

abstract：:The effects of 5-hydroxytryptamine (5-HT) on lateral horn cells contained in thin in vitro slices of neonatal rat spinal cord were investigated by means of intracellular recording techniques. Superfusion of 5-HT (1-100 microM) to lateral horn cells caused a concentration-dependent membrane depolarization leading to, i...

journal_title：Brain research

authors： Ma RC,Dun NJ

更新日期：1986-01-01 00:00:00

abstract：:The localization of human hand primary motor area (M1) has been the object of several studies during the last decades. EEG source analysis, functional magnetic resonance imaging (fMRI) and focal transcranial magnetic stimulation (TMS) are non-invasive methods for localizing M1 with good accuracy compared to direct ele...

journal_title：Brain research

authors： Inuggi A,Filippi M,Chieffo R,Agosta F,Rocca MA,González-Rosa JJ,Cursi M,Comi G,Leocani L

更新日期：2010-01-13 00:00:00

abstract：:Rats were bilaterally olfactory bulbectomized. At 15 days post-lesion, olfactory bulbectomized (OB) rats exhibited significant deficits in the acquisition of passive avoidance learning compared to sham lesioned rats. beta-Adrenoceptor binding in the amygdala, hippocampus and cerebral cortex was assayed with (-)-[125I]...

journal_title：Brain research

authors： Tiong AH,Richardson JS

更新日期：1990-10-29 00:00:00

abstract：:The effect of central and peripheral administration of a nitric oxide synthase inhibitor, N-nitro-L-arginine methyl ester (L-NAME), on morphine hyperthermia was studied in male Sprague-Dawley rats. The first series of experiments examined the effect of subcutaneous (s.c.) administration of L-NAME on the hyperthermia i...

journal_title：Brain research

authors： Benamar K,Xin L,Geller EB,Adler MW

更新日期：2001-03-16 00:00:00

abstract：:To investigate the reversibility of neuronal functions during deep and mild hypothermia, we have examined changes in membrane properties of pyramidal neurons of the CA3 region of hippocampal slices during cooling and rewarming (8 approximately 37 degrees C) of the perfusion medium. Hypothermia reduced the excitatory p...

journal_title：Brain research

authors： Aihara H,Okada Y,Tamaki N

更新日期：2001-03-02 00:00:00

abstract：:The distribution of retinal ganglion cells (RGCs) providing input to the thalamofugal visual system in the pigeon was studied with an anatomical transneuronal transport technique using the fluorescent dye rhodamine beta-isothiocyanate (RITC). Unilateral injections of RITC made into the telencephalic visual Wulst resul...

journal_title：Brain research

authors： Miceli D,Repérant J,Medina M,Volle M,Rio JP

更新日期：2006-07-07 00:00:00

abstract：:Bilateral intraventricular injections of 6-hydroxydopamine depleted dopamine (DA) in striatal tissue of rats by 88%. Tail shock increased DA in striatal extracellular fluid of these rats from 10 to 17 pg/20 microliters as measured by microdialysis, values less than half those seen in normal striatum. The increase was ...

journal_title：Brain research

authors： Keefe KA,Stricker EM,Zigmond MJ,Abercrombie ED

更新日期：1990-09-17 00:00:00

abstract：:Retinotectal projections were studied in 33 different species of Actinopterygii, the ray-finned fishes, with horseradish peroxidase and cobalt tracing techniques. The distribution of retinorecipient layers in the contralateral optic tectum was analyzed. In addition, the degree of differentiation of the stratum periven...

journal_title：Brain research

authors： von Bartheld CS,Meyer DL

更新日期：1987-09-15 00:00:00

abstract：:At various times after spinal nerve injury, dorsal root ganglia (DRGs) from injured segments were removed with attached dorsal roots and spinal nerves. In an in vitro recording chamber, spontaneously active units were recorded from teased dorsal root fascicles. Sustained spontaneous activity could first be recorded at...

journal_title：Brain research

authors： Liu X,Chung K,Chung JM

更新日期：1999-12-04 00:00:00

abstract：:Focal axonal swellings are characteristic of a wide range of neuropathies. Three neuron-specific monoclonal antibodies have been used to identify focal axonal swellings in the normal developing rat cerebellar cortex. Between 7 and 15 days postnatal, swellings are a common feature of the granular layer and white matter...

journal_title：Brain research

authors： Gravel C,Leclerc N,Plioplys A,Hawkes RB

更新日期：1986-01-22 00:00:00

abstract：:Tumor necrosis factor-alpha (TNFalpha) affects several CNS functions such as regulation of sleep, body temperature, and feeding during pathology. There is also evidence for TNFalpha involvement in physiological sleep regulation, e.g., TNFalpha induces sleep and brain levels of TNFalpha increase during prolonged wakefu...

journal_title：Brain research

authors： De A,Krueger JM,Simasko SM

更新日期：2005-08-16 00:00:00