Experimental studies on the olfactory marker protein. I. Presence of the olfactory marker protein in tufted and mitral cells.

Abstract:

:Partial, unilateral olfactory nerve section was performed in mice, and the behavior of the olfactory marker protein (OMP) studied, after this experimental manipulation, with the peroxidase--antiperoxidase method. The protein, which in normal mice is present only in mature olfactory sensory neurons, after unilateral lesion of the fila olfactoria was observed in mitral and tufted cells of both olfactory bulbs. Positive elements, present at 5 days postoperative, increased in number up to 30 days and some could still be detected at 60 days. The functional implications of this finding are briefly discussed.

journal_name

Brain Res

journal_title

Brain research

authors

Monti Graziadei GA,Graziadei PP

doi

10.1016/0006-8993(81)90162-1

subject

Has Abstract

pub_date

1981-03-30 00:00:00

pages

405-10

issue

2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(81)90162-1

journal_volume

209

pub_type

杂志文章
  • Mechanism of altered synaptic strength due to experience: relation to long-term potentiation.

    abstract::An increase in medial perforant synaptic strength can be observed for hippocampal slices from rats exposed to environmental enrichment. The expression of enhanced synaptic strength exhibits properties similar to long-term potentiation (LTP), a physiological model of memory storage. Similarities include an increase in ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(96)00707-x

    authors: Foster TC,Gagne J,Massicotte G

    更新日期:1996-10-14 00:00:00

  • Responsiveness of rat vestibular ganglion neurons to exogenous neurotrophic factors during postnatal development in dissociated cultures.

    abstract::We examined the responsiveness of rat vestibular ganglion neurons (VGNs) to exogenous neurotrophic factors, BDNF, NT-3, and GDNF, during postnatal development in dissociated cultures. VGNs were obtained from postnatal days (P) 1, 3, 7, and 14. After two days in culture, the survival of VGNs in control cultures without...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2011.06.058

    authors: Chihara Y,Iwasaki S,Kondo K,Yamasoba T

    更新日期:2011-08-23 00:00:00

  • Chronic intraventricular administration of lysergic acid diethylamide (LSD) affects the sensitivity of cortical cells to monocular deprivation.

    abstract::In kittens, but not in adult cats, depriving one eye of pattern vision by suturing the lids shut (monocular deprivation or MD) for one week reduces the proportion of binocular units in the visual cortex. A sensitivity of cortical units in adult cats to MD can be produced by infusing exogenous monoamines into the visua...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(82)90424-3

    authors: McCall MA,Tieman DG,Hirsch HV

    更新日期:1982-11-04 00:00:00

  • Beta-alanine uptake is not a marker for brain astroglia in culture.

    abstract::The properties of the beta amino acid transport system were examined in cultivated rat brain astrocytes, using the specific probe, beta-alanine. The uptake of beta-alanine is thought to be glial specific. Beta-alanine was not actively transported and the intracellular accumulation was not altered by coincubation with ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(82)90856-3

    authors: Cummins CJ,Glover RA,Sellinger OZ

    更新日期:1982-05-06 00:00:00

  • Region-specific alterations of calbindin-D28k immunoreactivity in the rat hippocampus following adrenalectomy and corticosterone treatment.

    abstract::The aim of this study was (i) to compare the immunocytochemical distribution of the calcium-binding protein calbindin-D28k (CB) in the hippocampus of rats with the pattern of neurodegeneration following adrenalectomy (ADX) using silver impregnation, and (ii) to investigate the CB-immunoreactivity in the hippocampus fo...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(95)00783-m

    authors: Krugers HJ,Medema RM,Postema F,Korf J

    更新日期:1995-10-23 00:00:00

  • Remote astrocytic response of prefrontal cortex is caused by the lesions in the nucleus basalis of Meynert, but not in the ventral tegmental area.

    abstract::The nucleus basalis of Meynert (nbM) was lesioned by injection of ibotenic acid, in 200 g male Wistar rats. The rats were killed 1, 3, 7 or 21 days after surgery, the brains were removed and the prefrontal cortices were subjected to immunohistochemical and Western blot analysis for the expression of glial fibrillary a...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(92)90800-o

    authors: Anezaki T,Yanagisawa K,Takahashi H,Nakajima T,Miyashita K,Ishikawa A,Ikuta F,Miyatake T

    更新日期:1992-03-06 00:00:00

  • Receptor blockade reveals a correspondence between hippocampal-dependent behavior and experience-dependent synaptic enhancement.

    abstract::This study examined the involvement of N-methyl-D-aspartate receptors (NMDARs) in experience-dependent synaptic plasticity. Rats chronically received an NMDA receptor antagonist (AP5) or saline (SAL) and were exposed to individual cages (IC) or environmental enrichment (EC). AP5 impaired measures of hippocampal-depend...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(00)02379-9

    authors: Foster TC,Fugger HN,Cunningham SG

    更新日期:2000-07-14 00:00:00

  • Functional recovery of the ventilatory chemoreflexes after partial chronic denervation of the nucleus tractus solitarius.

    abstract::In pentobarbitone-anesthetized cats breathing spontaneously, we studied whether excision of one petrosal ganglion would modify the reflex efficacy of the remaining carotid and aortic chemoafferences in ventilatory control. Resting ventilation was not affected shortly after the ganglionectomy, but decreased sensitiviti...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(90)91495-3

    authors: Eugenin J,Larrain C,Zapata P

    更新日期:1990-07-23 00:00:00

  • Curcumin protects pre-oligodendrocytes from activated microglia in vitro and in vivo.

    abstract::Infection and inflammation leading to injury or death of pre-oligodendrocytes (preOLs) is one of the principal initiating mechanisms in the pathogenesis of preterm periventricular leukomalacia (PVL). The present study explores the possible protective effect of curcumin against the toxicity of lipopolysaccharide (LPS)-...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2010.04.014

    authors: He LF,Chen HJ,Qian LH,Chen GY,Buzby JS

    更新日期:2010-06-21 00:00:00

  • Membrane currents elicited by the epileptogenic drug pentylenetetrazole in the native oocyte of Xenopus laevis.

    abstract::The effects of the epileptogenic agent pentylenetetrazole (PTZ) on membrane currents of native oocytes of Xenopus laevis were studied. PTZ elicits a response that consists of two inward currents. The first one is interpreted to be due to a decrease of potassium permeability since: (1) the input resistance is increased...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(91)90225-k

    authors: Madeja M,Musshoff U,Kuhlmann D,Speckmann EJ

    更新日期:1991-07-05 00:00:00

  • The action of MPTP on synaptic transmission is affected by changes in Ca2+ concentrations.

    abstract::1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) causes a disruption of nigrostriatal dopaminergic function which resembles parkinsonism. On the cellular level, the disruption involves a Ca2+ independent release of dopamine, depletion of nigral and striatal dopamine, and the death of dopaminergic neurons. We have p...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(91)91035-y

    authors: Wilson JA,Lau YS,Gleeson JG,Wilson JS

    更新日期:1991-02-15 00:00:00

  • NMDA receptor-mediated extracellular adenosine accumulation is blocked by phosphatase 1/2A inhibitors.

    abstract::We have previously demonstrated that NMDA receptor-mediated extracellular adenosine accumulation in neuronal cultures is receptor-mediated and requires calcium influx. Because protein kinase C (PKC) is a calcium-dependent enzyme, we hypothesized that activation of PKC might be involved in NMDA-mediated adenosine accum...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2007.04.057

    authors: Lu Y,Rosenberg PA

    更新日期:2007-06-25 00:00:00

  • Responses to force perturbations preceding voluntary human arm movements.

    abstract::Brief force perturbations were applied 30-120 ms prior to onset of step-tracking forearm movements by normal humans. The perturbations altered the first agonist burst of the movement-related triphasic EMG pattern. Perturbations opposing the movement resulted in an increase in the magnitude of the late part of the firs...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(81)91224-5

    authors: Brown SH,Cooke JD

    更新日期:1981-09-14 00:00:00

  • Chemical activation of the mesencephalic locomotor region.

    abstract::Electrical stimulation of the mesencephalic locomotor region (MLR) in the precollicular-postmammillary transected cat is known to induce controlled locomotion on a treadmill. We have been able to induce and block locomotion in this preparation by using localized infusions of transmitters and their agonists and antagon...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(85)90006-x

    authors: Garcia-Rill E,Skinner RD,Fitzgerald JA

    更新日期:1985-03-18 00:00:00

  • Responses of monkey prefrontal neurons during a visual tracking task reinforced by substantia innominata self-stimulation.

    abstract::The role of the substantia innominata (SI) in the generation of a behavior mediated by the prefrontal (PF) cortex was examined in two Japanese monkeys. PF neuronal activities related to a visual tracking task by wrist movement were recorded and neural responses to SI stimulation were analyzed. Sixty-six neurons showed...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(83)90734-5

    authors: Funahashi S

    更新日期:1983-10-16 00:00:00

  • The rostral projection of small diameter primary afferents in Lissauer's tract.

    abstract::The rostral projection of A delta and C primary afferents in Lissauer's tract (LT) was studied by assessing how far, rostrally, axons entering at a given level could be activated by electrical stimulation. Sural A delta primary afferents in LT exhibited a rostral projection at least as far as the L3/L4 border, 4 segme...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(86)90617-7

    authors: Traub RJ,Sedivec MJ,Mendell LM

    更新日期:1986-12-03 00:00:00

  • Effects of REM sleep deprivation on cholinergic receptor sensitivity and passive avoidance behavior in clomipramine model of depression.

    abstract::This study investigated the effects of REM (rapid eye movement) sleep deprivation (RSD) on the activity of central cholinergic receptors and passive avoidance retention in rats treated neonatally with clomipramine. Male rat pups treated with clomipramine (15 mg/kg, s.c.) twice daily from postnatal day 5 to 21 were sub...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(00)02248-4

    authors: Prathiba J,Kumar KB,Karanth KS

    更新日期:2000-06-09 00:00:00

  • Haloperidol induces Fos expression in the globus pallidus and substantia nigra of cynomolgus monkeys.

    abstract::Systemic injections of the dopamine antagonist haloperidol (0.1-2.5 mg/kg) induced a dose dependent increase in Fos-like immunoreactivity (FLI) in the internal segment of the globus pallidus (GPi) and in the substantia nigra (SN) of cynomolgus monkeys. These findings are consistent with models of basal ganglia organiz...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(99)01550-4

    authors: Wirtshafter D,Asin KE

    更新日期:1999-07-24 00:00:00

  • Selective activation of mesolimbic and mesocortical dopamine metabolism in rat brain by infusion of a stable substance P analogue into the ventral tegmental area.

    abstract::Microinfusion of the metabolically stable substance P (SP) agonist, [pGlu5,MePhe8,Sar9]-SP5-11 (DiMe-C7), into the ventral tegmental area (VTA) of rat brain increased levels of the dopamine (DA) metabolite dihydroxyphenylacetic acid in the prefrontal cortex (+ 120%) and nucleus accumbens (+30%) but not in other region...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(86)90667-0

    authors: Elliott PJ,Alpert JE,Bannon MJ,Iversen SD

    更新日期:1986-01-15 00:00:00

  • Aqueduct stenosis induced by a single injection of antivitamin.

    abstract::Hydrocephalus with aqueduct stenosis was a consistent feature in mice which received a single intraperitoneal injection of 6-aminonicotinamide (6-AN) on day 5 postnatal. Chronological investigation revealed that 6-AN-treated mice had aqueductal obstruction with edematously swollen ependymal cells and spongy changes in...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0165-3806(85)90180-4

    authors: Aikawa H,Suzuki K

    更新日期:1985-10-01 00:00:00

  • Anticonvulsant effect of enhancement of noradrenergic transmission in the superior colliculus in genetically epilepsy-prone rats (GEPRs): a microinjection study.

    abstract::An expanding body of data has indicated that the seizure prone state in genetically epilepsy-prone rats (GEPRs) is partially caused by deficits in central nervous system noradrenergic transmission. Several lines of evidence suggest that the noradrenergic terminals in the superior colliculus (SC) may act as determinant...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(97)01139-6

    authors: Yan QS,Dailey JW,Steenbergen JL,Jobe PC

    更新日期:1998-01-12 00:00:00

  • Location and axonal projection of one type of swallowing interneurons in cat medulla.

    abstract::Extracellular recordings were made from a type of relay neurons of the superior laryngeal nerve (SLN) afferents in the vicinity of the retrofacial nucleus (RFN) in either pentobarbitone-anesthetized or unanesthetized and decerebrate cats, which were paralyzed and artificially ventilated. A total of 26 neurons that cou...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(93)91156-m

    authors: Ezure K,Oku Y,Tanaka I

    更新日期:1993-12-31 00:00:00

  • Central changes in nociceptin dynorphin B and Met-enkephalin-Arg-Phe in different models of nociception.

    abstract::The newly identified neuropeptide nociceptin/orphanin FQ (NOC) was measured in different rat brain areas related to the descending anti-nociceptive pathways and compared to two opioid peptides, dynorphin B (DYN B) and Met-enkephalinArgPhe (MEAP). Two experimental models of chronic nociception, one neurogenic and one i...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(99)02432-4

    authors: Rosén A,Lundeberg T,Bytner B,Nylander I

    更新日期:2000-02-28 00:00:00

  • Physostigmine and acetylcholine differentially activate nicotinic receptor subpopulations in Locusta migratoria neurons.

    abstract::The effects of acetylcholine (ACh) and physostigmine (PHY) on thoracic ganglion neurons of Locusta migratoria were investigated using whole-cell and cell-attached voltage clamp. ACh activated whole-cell currents with variable amplitudes, time course and ion channel block between cells, suggesting differential expressi...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(98)00007-9

    authors: van den Beukel I,van Kleef RG,Zwart R,Oortgiesen M

    更新日期:1998-04-13 00:00:00

  • A spontaneous tonic chloride conductance in solitary glutamatergic hippocampal neurons.

    abstract::GABA-A receptors mediate both phasic synaptic inhibition and more recently appreciated tonic currents in the vertebrate central nervous system. We addressed discrepancies in the literature regarding the pharmacology of tonic currents by examining tonic currents in a controlled environment of dissociated, solitary glut...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2006.08.033

    authors: Eisenman LN,Kress G,Zorumski CF,Mennerick S

    更新日期:2006-11-06 00:00:00

  • Protein phosphatase inhibitors prolong Ca(2+)-transients and divalent cation-dependent action potentials in leech Retzius cells.

    abstract::Elevation of [K+]o for 30 s from 4 to 120 mM produced a fast and reversible depolarization and transient increase in [Ca2+]i in fura-2 loaded Retzius cells of the leech. The protein phosphatase inhibitor, okadaic acid, significantly slowed the return of [Ca2+]i toward baseline without affecting the amplitude of depola...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(94)91800-7

    authors: Kleinhaus AL,Zeman RJ

    更新日期:1994-07-11 00:00:00

  • Modulation of salt appetite by lateral ventricular infusions of angiotensin II and carbachol during sodium depletion.

    abstract::Infusions of angiotensin II (AII) or carbachol (CBC) into the lateral ventricles of rats which had been depleted of sodium 4 h previously with either furosemide or polyethylene glycol produced significant changes in salt appetite and sodium and water balances relative to rats infused with saline vehicle. Infusions of ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(85)90860-1

    authors: Fitts DA,Thunhorst RL,Simpson JB

    更新日期:1985-11-04 00:00:00

  • Structure and function of urodele myelin lacking alpha-hydroxy fatty acid-containing galactosphingolipids: slow nerve conduction and unusual myelin thickness.

    abstract::Myelin of several Caudata (Urodela) species appears to be unique in the fact that it lacks hydroxycerebrosides and hydroxysulfatides although it contains their non-hydroxy counterparts. Comparison of the nerve conduction velocities in the Urodeles Necturus (salamander) and Notophthalmus (newt) with that in a reptile, ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(85)90831-5

    authors: Ki PF,Kishimoto Y,Lattman EE,Stanley EF,Griffin JW

    更新日期:1985-10-14 00:00:00

  • Evidence for 5-HT4 receptor involvement in the enhancement of acetylcholine release by p-chloroamphetamine in rat frontal cortex.

    abstract::The roles of endogenous serotonin (5-HT) and 5-HT receptor subtypes in regulation of acetylcholine (ACh) release in frontal cortex of conscious rats were examined using a microdialysis technique. Systemic administration (1 and 3 mg/kg, i.p.) of the 5-HT-releasing agent p-chloroamphetamine (PCA) elevated ACh output in ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(97)00856-1

    authors: Yamaguchi T,Suzuki M,Yamamoto M

    更新日期:1997-10-24 00:00:00

  • Fos protein expression in the nucleus of the solitary tract in response to intestinal nutrients in awake rats.

    abstract::Nutrients in the intestine inhibit food intake via an action on the vagal afferent pathway. The aim of the present study was to use immunochemical detection of Fos protein-like immunoreactivity (FLI) in the brainstem to trace the neuronal pathways activated by intestinal nutrients. Perfusion of the intestine of awake ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(94)91272-6

    authors: Zittel TT,De Giorgio R,Sternini C,Raybould HE

    更新日期:1994-11-14 00:00:00