Analysis of protein levels and synthesis after learning in the split-brain pigeon.

Abstract:

:A series of experiments were performed to study the effects of learning upon proteins in the split-brain pigeon. With this preparation, one side of the brain was trained in a color discrimination task while the other side served as a naive control. Proteins from both sides of the brain were separated by one- and two-dimensional polyacrylamide gel electrophoresis and analyzed to measure protein levels or protein synthesis. No differences were found between trained and naive telencephalic hemispheres or between trained and naive optic lobes in the steady-state protein levels or in protein synthesis.

journal_name

Brain Res

journal_title

Brain research

authors

Deutsch DG,Schechter N,Brecha N,Quitschke W,Schulman P,Cane M,Gazzaniga MS,Simpson MV

doi

10.1016/0006-8993(80)90349-2

subject

Has Abstract

pub_date

1980-09-29 00:00:00

pages

135-45

issue

1

eissn

0006-8993

issn

1872-6240

pii

0006-8993(80)90349-2

journal_volume

198

pub_type

杂志文章
  • The pattern of retinoic acid receptor expression and subcellular, anatomic and functional area translocation during the postnatal development of the rat cerebral cortex and white matter.

    abstract::Retinoic acid (RA), which is an important modulator of brain development, neural cell proliferation, neurite outgrowth, and synaptic plasticity, is regulated via changes in RA receptors. The pattern of RA receptor changes in the rat cerebral cortex and white matter during postnatal development has not been extensively...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2011.01.027

    authors: Jiang W,Wen EY,Gong M,Shi Y,Chen L,Bi Y,Zhang Y,Liu YF,Chen J,Qu P,Liu YX,Wei XP,Li TY

    更新日期:2011-03-25 00:00:00

  • Opioid receptor regulation of 5-hydroxytryptamine release from the rat hippocampus measured by in vivo microdialysis.

    abstract::The modulation of serotonin (5-HT) release by opioid receptors in the hippocampus of the awake, unrestrained rat was evaluated by use of in vivo microdialysis. The hippocampus was perfused with Ringer's solution (2 microliters/min), and extracellular levels of 5-HT and its major metabolite, 5-hydroxyindoleacetic acid ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(93)90456-w

    authors: Yoshioka M,Matsumoto M,Togashi H,Smith CB,Saito H

    更新日期:1993-06-04 00:00:00

  • Immunocytochemical localization of corticotropin releasing factor (CRF) in the rat spinal cord.

    abstract::The presence of corticotropin releasing factor (CRF)-immunoreactive nerve fibers and cell bodies in the spinal cord is demonstrated. Immunopositive fibers were found in the lateral column of the white matter, in laminae I, V-VII, X, and in the intermediolateral column of the spinal cord. Complete transection of the sp...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(83)91001-6

    authors: Merchenthaler I,Hynes MA,Vigh S,Shally AV,Petrusz P

    更新日期:1983-09-26 00:00:00

  • Increased vessel diameter of leptomeningeal anastomoses after hypoxic preconditioning.

    abstract::Recently, cerebral blood flow changes were re-discussed to contribute to tissue protection after preconditioning. In the present study, we demonstrate increased vessel diameters of the leptomeningeal anastomoses after hypoxic preconditioning by visualization of the brain angioarchitecture using the latex perfusion tec...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2006.07.081

    authors: Woitzik J,Hecht N,Schneider UC,Peña-Tapia PG,Vajkoczy P

    更新日期:2006-10-18 00:00:00

  • Entorhinal and prepiriform cortices of the European hedgehog. A histochemical and densitometric study based on a comparison between Timm's sulphide silver method and the selenium method.

    abstract::The Timm and selenium staining techniques, based on silver amplification of endogenous zinc, produce an electron-dense precipitate in boutons. The staining characteristics of the two methods were compared by examining two allocortical regions, prepiriform cortex and entorhinal cortex, in the brain of the European hedg...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(85)90361-0

    authors: Schwerdtfeger WK,Danscher G,Geiger H

    更新日期:1985-11-25 00:00:00

  • Redistribution of Kv2.1 ion channels on spinal motoneurons following peripheral nerve injury.

    abstract::Pathophysiological responses to peripheral nerve injury include alterations in the activity, intrinsic membrane properties and excitability of spinal neurons. The intrinsic excitability of α-motoneurons is controlled in part by the expression, regulation, and distribution of membrane-bound ion channels. Ion channels, ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2013.12.012

    authors: Romer SH,Dominguez KM,Gelpi MW,Deardorff AS,Tracy RC,Fyffe RE

    更新日期:2014-02-14 00:00:00

  • Longitudinal white matter changes in Alzheimer's disease: a tractography-based analysis study.

    abstract::Alzheimer's disease (AD) classically presents with gray matter atrophy, as well as feature significant white matter abnormalities. Previous evidence indicates the overall burden of these pathological changes continues to advance as the disease progresses. The aim of this study was to investigate whether pathological a...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2013.03.052

    authors: Kitamura S,Kiuchi K,Taoka T,Hashimoto K,Ueda S,Yasuno F,Morikawa M,Kichikawa K,Kishimoto T

    更新日期:2013-06-17 00:00:00

  • Swallowing during ongoing fluid ingestion in the rat.

    abstract::In order to identify fixed versus flexible aspects of swallowing and oromotor control, we developed a method for the concurrent analysis of swallow frequency, swallow volume, and the temporal correlation between swallowing and rhythmic orolingual movements during prolonged bouts of fluid ingestion in unanesthetized, u...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(89)91135-9

    authors: Kaplan JM,Grill HJ

    更新日期:1989-10-09 00:00:00

  • Loss of benefit from estrogen replacement therapy in diabetic ovariectomized female rats subjected to transient forebrain ischemia.

    abstract::In nondiabetic animals, estrogen has been shown to provide significant neuroprotection in focal and transient forebrain ischemia models. However, that neuroprotection may be diminished or lost in the diabetic. In this study, we compared the level of brain damage in intact, ovariectomized (OVX) and 17beta-estradiol (E(...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(02)03484-4

    authors: Santizo RA,Xu HL,Ye S,Baughman VL,Pelligrino DA

    更新日期:2002-11-22 00:00:00

  • A solution hybridization assay for the quantitation of prodynorphin mRNA.

    abstract::We have developed a RNA-RNA solution hybridization assay to quantitate the mRNA coding for prodynorphin precursor. This assay is extremely sensitive and highly specific. Using this assay we have measured the prodynorphin mRNA in various brain regions and reproductive tissues of rat. When we compared the distribution o...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(87)80011-2

    authors: Devi L,Douglass J,Herbert E

    更新日期:1987-07-01 00:00:00

  • Differential distribution of cellular forms of beta-amyloid precursor protein in murine glial cell cultures.

    abstract::The production and localization of cell-associated forms of beta-amyloid precursor protein (APP) of Alzheimer's disease was investigated in primary cultures of mouse glial cells. In both oligodendrocytes and astrocytes, immunofluorescence staining with an antibody against the carboxy terminus of APP revealed an intens...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(92)90898-j

    authors: Mizuguchi M,Ikeda K,Kim SU

    更新日期:1992-07-03 00:00:00

  • Protective effect of diazepam pretreatment on soman-induced brain lesion formation.

    abstract::Histopathological analyses of brains of rats receiving a single 0.9 LD50 injection of soman, a potent anticholinesterase neurotoxin, revealed massive widespread lesions in the cerebral cortex and thalamus 4 weeks post-injection. Such lesions were not evidenced in rats receiving diazepam (2.2 mg/kg, i.m.) 10 min prior ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(85)90324-5

    authors: Martin LJ,Doebler JA,Shih TM,Anthony A

    更新日期:1985-01-28 00:00:00

  • The expression of the intermediate filament-associated protein (NAPA-73) is associated with the stage of terminal differentiation of chick brain neurons.

    abstract::The monoclonal antibody E/C8 was originally generated against chicken dorsal root ganglia. The antigen detected by E/C8, NAPA-73, is an intermediate filament-associated protein. NAPA-73 was shown to be one of the earliest neuronal markers to appear during development since it appears in some neuronal precursor cells o...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(87)91289-3

    authors: Wu DK,de Vellis J

    更新日期:1987-09-22 00:00:00

  • Dopamine D2 receptor control of pallidal fos expression: comparisons between intact and 6-hydroxydopamine-treated hemispheres.

    abstract::Fos expression in the globus pallidus (GP) of rats was elicited by the D2 agonist quinpirole both ipsilateral and contralateral to a unilateral nigrostriatal 6-hydroxydopamine (6-OHDA) injection; however, the 6-OHDA-treated hemisphere was more sensitive to this effect. The quinpirole-induced GP Fos expression was anta...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(93)91166-p

    authors: Marshall JF,Cole BN,LaHoste GJ

    更新日期:1993-12-31 00:00:00

  • Effects of L-DOPA on neuronal activity of the globus pallidus externalis (GPe) and globus pallidus internalis (GPi) in the MPTP-treated monkey.

    abstract::We studied the effects of L-DOPA on the firing patterns of pallidal neurons in experimental parkinsonism. After a unilateral injection of MPTP, we observed a decrease in the firing rate of GPe neurons, and a slight increase in their bursting activity. In the GPi, there was a considerable augmentation of both neuronal ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(97)01563-1

    authors: Boraud T,Bezard E,Guehl D,Bioulac B,Gross C

    更新日期:1998-03-16 00:00:00

  • GABA- and glycine-induced Cl- channels in cultured mouse spinal neurons require the same energy to close.

    abstract::Fluctuation analysis has been used to study the influence of temperature on the conductance and mean open time of Cl- permeable ion channels induced by gamma-aminobutyric acid (GABA) and glycine in the membrane of tissue cultured mouse spinal neurons. The conductance of GABA- and glycine-activated channels increased s...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(81)90875-1

    authors: Mathers DA,Barker JL

    更新日期:1981-11-16 00:00:00

  • Quantitative correlation between tetanus-induced decreases in extracellular calcium and LTP.

    abstract::Decreases in the extracellular calcium concentration ([Ca2+]o), induced by tetanization of the Schaffer collaterals in rat hippocampal slices, were measured by means of Ca2+-sensitive microelectrodes. The amount of long term potentiation (LTP) of the evoked field potentials, induced by this tetanus, was determined. A ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(88)90798-6

    authors: Melchers BP,Pennartz CM,Wadman WJ,Lopes da Silva FH

    更新日期:1988-06-28 00:00:00

  • Signal transmission from the suprachiasmatic nucleus to the pineal gland via the paraventricular nucleus: analysed from arg-vasopressin peptide, rPer2 mRNA and AVP mRNA changes and pineal AA-NAT mRNA after the melatonin injection during light and dark per

    abstract::Arg-vasopressin (AVP) containing neurons are one of the output paths from the suprachiasmatic nucleus (SCN), the center of the biological clock. AVP mRNA transcription is controlled by a negative feedback loop of clock genes. Circadian rhythm of melatonin release from the pineal gland is regulated by the SCN via the p...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2004.04.052

    authors: Isobe Y,Nishino H

    更新日期:2004-07-09 00:00:00

  • Modulation of dopamine uptake by nitric oxide in cultured mesencephalic neurons.

    abstract::Strong evidence obtained from in vivo and ex-vivo studies suggests the existence of interaction between dopaminergic and nitrergic systems. Some of the observations suggest a possible implication of nitric oxide (NO) in dopamine (DA) uptake mechanism. The present work investigated the interaction between both systems ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2007.12.054

    authors: Salum C,Raisman-Vozari R,Michel PP,Gomes MZ,Mitkovski M,Ferrario JE,Ginestet L,Del Bel EA

    更新日期:2008-03-10 00:00:00

  • Brain-derived neurotrophic factor stimulates survival and neuronal differentiation in cultured avian neural crest.

    abstract::The response of trunk neural crest cells taken from precise levels of the neural axis and cultured together with adjacent somites to Brain-derived neurotrophic factor (BDNF), was examined in cultures grown in a chemically defined medium. In control cultures, the number of neural crest-derived neurons expressing the HN...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0165-3806(88)90171-x

    authors: Kalcheim C,Gendreau M

    更新日期:1988-06-01 00:00:00

  • Cerebral angiogenesis after collagenase-induced intracerebral hemorrhage in rats.

    abstract::Spontaneous intracerebral hemorrhage (ICH) is one of the most devastating subtypes of stroke. Since angiogenesis is a fundamental process to brain development and repair by new blood vessel formation from pre-existing ones, mediated by numerous angiogenic factors including vascular endothelial growth factor (VEGF), th...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2007.08.028

    authors: Tang T,Liu XJ,Zhang ZQ,Zhou HJ,Luo JK,Huang JF,Yang QD,Li XQ

    更新日期:2007-10-17 00:00:00

  • Noradrenergic innervation of human pineal gland: abnormalities in aging and Alzheimer's disease.

    abstract::Using previously characterized polyclonal antibody directed against dopamine beta-hydroxylase (DBH), immunoreactive fibers were demonstrable in pineals of 6 controls of various ages and of 3 individuals with Alzheimer's disease (AD). Abnormal, swollen axons were present in pineals from aged individuals and from indivi...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(89)90818-4

    authors: Jengeleski CA,Powers RE,O'Connor DT,Price DL

    更新日期:1989-03-06 00:00:00

  • The network-selective actions of quinoxalines on the neurocircuitry operations of the rabbit retina.

    abstract::We examined the contribution of N-methyl-D-aspartate (NMDA) and alpha-amino-3-hydroxy-5-methyl-4-isoxalole-4-propionic acid (AMPA)/kainate (KA) receptors to the light-responses of rabbit retinal neurons. In the outer retina, bath application of the AMPA/KA receptor antagonists 6,7-dinitro-quinoxaline-2,3-dione (DNQX) ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(99)01448-1

    authors: Cohen ED,Miller RF

    更新日期:1999-06-12 00:00:00

  • Stress and beta-carbolines decrease the density of low affinity GABA binding sites; an effect reversed by diazepam.

    abstract::Cerebral cortex membranes from rats habituated to manipulations preceding decapitation (habituated rats) had 40% higher GABA binding than membranes from naive animals. Diazepam (5 X 10(-6) M), added to membranes from naive rats, increased GABA binding to the level of habituated rats, but failed to induce any further i...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(84)91114-4

    authors: Biggio G,Concas A,Serra M,Salis M,Corda MG,Nurchi V,Crisponi C,Gessa GL

    更新日期:1984-07-02 00:00:00

  • Electrophysiological evidence for the existence of GABAA receptors in cultured frog melanotrophs.

    abstract::The neurotransmitter GABA exerts a biphasic effect on alpha-melanocyte-stimulating hormone (alpha-MSH) secretion from pars intermedia cells: GABA induces a rapid and transient stimulation followed by a sustained inhibition of alpha-MSH release. In the present study, we have investigated the effect of GABA on the elect...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(90)91020-h

    authors: Louiset E,van de Put FH,Tonon MC,Basille C,Jenks BG,Vaudry H,Cazin L

    更新日期:1990-05-28 00:00:00

  • Glutamate selectively increases the high-threshold Ca2+ channel current in sensory and hippocampal neurons.

    abstract::Previous studies resulted in conflicting conclusions that glutamate application either decreases or increases the activity of Ca2+ channels in hippocampal neurons. We studied whole-cell Ca2+ currents (ICa) in chick dorsal root ganglion neurons and rat hippocampal cells. For both cell types glutamate (1-30 microM) incr...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(92)90965-c

    authors: Mironov SL,Lux HD

    更新日期:1992-05-15 00:00:00

  • Effects of antibiotics, minocycline and ampicillin, on human sleep.

    abstract::The effects of two kinds of antibiotics, minocycline (MNC) and ampicillin (AB-PC), on human sleep were investigated on 19 healthy male students to test for a relationship between human sleep and protein synthesis. These drugs and placebos were capsulated identically in appearance and were given to the subjects using t...

    journal_title:Brain research

    pub_type: 临床试验,杂志文章

    doi:10.1016/0006-8993(83)90101-4

    authors: Nonaka K,Nakazawa Y,Kotorii T

    更新日期:1983-12-12 00:00:00

  • Types and locations of respiratory-related neurons in lateral tegmental field of cat medulla oblongata.

    abstract::Extracellular microelectrode recordings were made from a total of 868 neurons in the medullas of cats in regions known to contain high densities of respiratory-related neurons (solitary tract complex, nucleus ambiguus/retroambigualis, lateral tegmental field). Both the discharge patterns and the locations of units wer...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(84)90979-x

    authors: King GW,Knox CK

    更新日期:1984-03-19 00:00:00

  • Hippocampal mediation of raphe lesion- and PCPA-induced hyperactivity in the rat.

    abstract::These experiments provide a direct test of the hypothesis that median raphe lesion- or PCPA-induced hyperactivity in the rat is mediated specifically by the hippocampus. Previous studies had shown that a marked depletion of hippocampal serotonin accompanied median lesion-induced hyperactivity. In the present studies, ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(75)90060-8

    authors: Jacobs BL,Trimbach C,Eubanks EE,Trulson M

    更新日期:1975-08-29 00:00:00

  • 2,3-Butanedione monoxime protects mice against the convulsant effect of picrotoxin by facilitating GABA-activated currents.

    abstract::While adult mice receiving picrotoxin (PTX) alone responded with clonic and tonic-clonic seizures, this response was greatly suppressed for mice simultaneously injected with 2,3-butanedione monoxime (BDM). For example, 60% and 10% of the mice convulsed when injected (i.p.) with 3.0 mg/kg PTX alone or PTX plus 205 mg/k...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(95)00175-p

    authors: Brightman T,Ye JH,Ortiz-Jimenez E,Flynn EJ,Wu WH,McArdle JJ

    更新日期:1995-04-24 00:00:00