Electrophysiological evidence for the existence of GABAA receptors in cultured frog melanotrophs.

abstract：:Ascending and descending projections of the nucleus reticularis gigantocellularis (NRGc) were studied in the cat by the anterograde tracer, Phaseolus vulgaris leucoagglutinin. Ascending fibers from the left or the right NRGc coursed through the bilateral medial reticular formation and some of them reached the dienceph...

journal_title：Brain research

authors： Matsuyama K,Ohta Y,Mori S

更新日期：1988-09-13 00:00:00

abstract：:Sex hormone binding globulin (SHBG) is produced in brain where it is often co-localized with oxytocin. Infusions of SHBG into the medial preoptic area-anterior hypothalamus facilitate female sexual receptivity. SHBG has receptors on plasma membranes of the prostate gland where binding of the 5alpha-reduced androgen di...

journal_title：Brain research

authors： Caldwell JD,Höfle S,Englöf I

更新日期：2002-09-06 00:00:00

abstract：:Unilateral injections of 6-hydroxydopamine into the lateral hypothalamus or ventral tegmental area that damage extensively the mesotelencephalic dopaminergic projection result in significant hemispheric asymmetries in autoradiographic labeling after [14C]2-deoxy-D-glucose (2DG) administration. The incorporation of thi...

journal_title：Brain research

authors： Kozlowski MR,Marshall JF

更新日期：1980-09-15 00:00:00

abstract：:Sera from patients with multiple sclerosis (MS) frequently produce demyelination of central nervous system tissue cultures. The nature of the factors responsible for demyelination is not as yet clearly established. However, several authors previously reported, in in vivo and in vitro models, demyelinating activity in ...

journal_title：Brain research

authors： Grundke-Iqbal I,Bornstein MB

更新日期：1979-01-19 00:00:00

abstract：:A reduction in adenosine deaminase acting on RNA 2 (ADAR2) activity causes the death of spinal motor neurons specifically via the GluA2 Q/R site-RNA editing failure in sporadic amyotrophic lateral sclerosis (ALS). We studied, over time, the spinal cords of ADAR2-knockout mice, which are the mechanistic model mice for ...

journal_title：Brain research

authors： Sasaki S,Takenari Yamashita,Hideyama T,Kwak S

更新日期：2014-03-06 00:00:00

abstract：:Rats were administered haloperidol (0.5 mg/kg/day) for 21 days. Twenty percent of locus coeruleus (LC) neurons recorded were not spontaneously active, while no such neuron was observed in control animals. A further 22% of neurons (spontaneously active) had rates greater than 2 standard deviations from the mean of LC c...

journal_title：Brain research

authors： Dinan TG,Aston-Jones G

更新日期：1985-01-28 00:00:00

abstract：:Superior colliculus cells that respond to a given sensory input (visual or auditory) were influenced by the presence of a stimulus in the other modality. This is a form of sensory-sensory integration which has previously been thought to be involved in initiating the orientation of receptor organs in response to such c...

journal_title：Brain research

authors： Peck CK

更新日期：1987-09-08 00:00:00

abstract：:There is a high incidence of cardiac arrest and poorer post-resuscitation outcome in the elderly population. Cardiac arrest and resuscitation results in ischemia/reperfusion injury associated with oxidative stress, leading to post-resuscitation mortality and delayed selective neuronal cell loss. In this study we inves...

journal_title：Brain research

authors： Xu K,Puchowicz MA,Sun X,LaManna JC

更新日期：2010-04-30 00:00:00

abstract：:Afferent pathways innervating the urinary bladder consist of myelinated Adelta- and unmyelinated C-fibers, the neuronal cell bodies of which correspond to medium and small-sized cell populations of dorsal root ganglion (DRG) neurons, respectively. Since hyperpolarization-activated cyclic nucleotide-gated cation (HCN) ...

journal_title：Brain research

authors： Matsuyoshi H,Masuda N,Chancellor MB,Erickson VL,Hirao Y,de Groat WC,Wanaka A,Yoshimura N

更新日期：2006-11-13 00:00:00

abstract：:Analysis of rat hypothalamic extracts by gel filtration and HPLC revealed the presence of a form of substance P-like immunoreactivity with a molecular weight of approximately 5,700 (6k-SP). 6k-SP is probably an N-terminally extended form of substance P; the peptide may be an intermediate in SP biosynthesis, or may fun...

journal_title：Brain research

authors： Harmar AJ,Armstrong A,Lee CM,Emson PC

更新日期：1984-12-10 00:00:00

abstract：:A disintegrin and metalloproteinase (ADAM) 12 represents a member of a large family of similarly structured multi-domain proteins. In the central nervous system (CNS), ADAM12 has been suggested to play a role in brain development, glioblastoma cell proliferation, and in experimental autoimmune encephalomyelitis. Furth...

journal_title：Brain research

authors： Baertling F,Kokozidou M,Pufe T,Clarner T,Windoffer R,Wruck CJ,Brandenburg LO,Beyer C,Kipp M

更新日期：2010-04-22 00:00:00

abstract：:This neuroimaging study investigated the neural mechanisms of the effect of conversation on visual event detection during a driving-like scenario. The static load paradigm, established as predictive of visual reaction time in on-road driving, measured reaction times to visual events while subjects watched a real-world...

journal_title：Brain research

authors： Hsieh L,Young RA,Bowyer SM,Moran JE,Genik RJ 2nd,Green CC,Chiang YR,Yu YJ,Liao CC,Seaman S

更新日期：2009-01-28 00:00:00

abstract：:We have elucidated the spatial and temporal localization of Cdk5 and p35nck5a in the developing rat postnatal cerebellum. Both proteins were highly expressed in cell bodies of post mitotic and immature neurons. The localization of Cdk5 in cellular compartment was changed from cell body to the axon in development. On t...

journal_title：Brain research

authors： Matsushita M,Tomizawa K,Lu YF,Moriwaki A,Tokuda M,Itano T,Wang JH,Hatase O,Matsui H

更新日期：1996-09-23 00:00:00

abstract：:Magnetic resonance spectroscopy (MRS) has demonstrated age-related changes in brain metabolites that may underlie micro-structural brain changes, but few studies have examined their relationship with cognitive decline. We performed a cross-sectional study of brain metabolism and cognitive function in 82 healthy adults...

journal_title：Brain research

authors： Charlton RA,McIntyre DJ,Howe FA,Morris RG,Markus HS

更新日期：2007-08-20 00:00:00

abstract：:Peripheral nerve fascicles are deliberately impaled during microneurography experiments. We have assessed conduction block under these circumstances. First we recorded compound action potentials (CAP) in the sural nerve following stimulation of the sciatic nerve. The insertion of injection and microneurography electro...

journal_title：Brain research

authors： Rice AS,McMahon SB,Wall PD

更新日期：1993-12-24 00:00:00

abstract：:Past studies in the rat and Syrian hamster show that metabolic and electrical activity of the suprachiasmatic nuclei (SCN) is inhibited by melatonin (MEL) at about circadian time (ct) 8-11 h. The present experiment examined the effect of MEL on the firing frequency of SCN cells in brain slices prepared from long day (...

journal_title：Brain research

authors： Margraf RR,Lynch GR

更新日期：1993-04-23 00:00:00

abstract：:The lactating rat has been shown to lack a behavioral response and immediate early gene expression (cFos) in the hippocampus (Hipc) following intravenous or intracerebroventricular administration of an N-methyl-d-aspartate (NMDA) receptor agonist. The purpose of this study is to determine whether neurons in the Hipc h...

journal_title：Brain research

authors： Grove KL,Smith MS

更新日期：1998-12-14 00:00:00

abstract：:The effects of the epileptogenic agent pentylenetetrazole (PTZ) on membrane currents of native oocytes of Xenopus laevis were studied. PTZ elicits a response that consists of two inward currents. The first one is interpreted to be due to a decrease of potassium permeability since: (1) the input resistance is increased...

journal_title：Brain research

authors： Madeja M,Musshoff U,Kuhlmann D,Speckmann EJ

更新日期：1991-07-05 00:00:00

abstract：:A recent physiological report suggested that neurotensin could inhibit the vasopressin releasing from vasopressin-producing neurons in the hypothalamic paraventricular nucleus but not in the supraoptic nucleus. In the present study, the synaptic relationship between the neurotensin-like immunoreactive and vasopressin-...

journal_title：Brain research

authors： Wang QP,Guan JL,Ochiai H,Nakai Y

更新日期：1999-07-10 00:00:00

abstract：:Nitric oxide (NO) is a neuronal messenger that it is thought to be involved in the nociceptive transmission modulation. The activity of nicotinamide adenine dinucleotide phosphate diaphorase (NADPH-d) was shown to be identical to NOS activity in the brain. Since the periaqueductal gray matter (PAG) plays an important ...

journal_title：Brain research

authors： Rodella L,Rezzani R,Agostini C,Bianchi R

更新日期：1998-05-18 00:00:00

abstract：:Hippocampal CA1 pyramidal neurons undergo delayed neurodegeneration after transient forebrain ischemia, and the phenomenon is dependent upon hyperactivation of l-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) subtype of glutamate receptors, resulting in aberrant intracellular calcium influx. The GluR2 sub...

journal_title：Brain research

authors： Kaur J,Zhao Z,Geransar RM,Papadakis M,Buchan AM

更新日期：2006-02-23 00:00:00

abstract：:Mesenchymal stem cell (MSC) transplantation has been reported to improve neurologic function after ischemic injury. However, the detailed mechanisms by which MSCs promote functional recovery are not fully understood. Interleukin-10 (IL-10) is a well-known anti-inflammatory cytokine with neuroprotective effects with re...

journal_title：Brain research

authors： Li J,Zhu H,Liu Y,Li Q,Lu S,Feng M,Xu Y,Huang L,Ma C,An Y,Zhao RC,Wang R,Qin C

更新日期：2010-06-02 00:00:00

abstract：:Glutamate is the main excitatory neurotransmitter in the central nervous system. This amino acid mediates learning and memory processes acting through ionotropic and metabotropic receptor binding. Metabotropic glutamate receptors (mGluRs) are G protein-coupled receptors that stimulate phospholipase C (PLC) or inhibit ...

journal_title：Brain research

authors： Iglesias I,Castillo CA,León D,Ruíz MA,Albasanz JL,Martín M

更新日期：2007-06-11 00:00:00

abstract：:The core neuropsychological processes underlying post-traumatic stress disorder (PTSD) have yet to be elucidated, and the association between anatomical and functional deficits in PTSD remains largely unknown. The aim of our study was to investigate the alterations in cortical thickness and amplitude of low-frequency ...

journal_title：Brain research

authors： Bing X,Ming-Guo Q,Ye Z,Jing-Na Z,Min L,Han C,Yu Z,Jia-Jia Z,Jian W,Wei C,Han-Jian D,Shao-Xiang Z

更新日期：2013-01-15 00:00:00

abstract：:Our previous studies have indicated that oxygen radicals, produced during reoxygenation following short-term arterial hypoxia, lead to sustained suppression of cerebral arteriolar responses to N-methyl-D-aspartate (NMDA). However, whether arteriolar dilator responses to NMDA are reduced during arterial hypoxia has nev...

journal_title：Brain research

authors： Bari F,Thore CR,Louis TM,Busija DW

更新日期：1998-01-12 00:00:00

abstract：:Although an auditory area has been found over the exposed area of lobules VI-VIII in the posterior cerebellar vermis of the cat, there has been little information on its buried portion. This point should be of some concern, since very little of the brain tissue in lobules VI-VIII of the cerebellar cortex is exposed. W...

journal_title：Brain research

authors： Huang CM,Liu GL

更新日期：1991-07-12 00:00:00

abstract：:The purpose of the present study is to examine the effects of mental fatigue and motivation on neural network dynamics activated during task switching. Mental fatigue was induced by 2 h of continuous performance; after which subjects were motivated by using social comparison and monetary reward as motivating factors t...

journal_title：Brain research

authors： Lorist MM,Bezdan E,ten Caat M,Span MM,Roerdink JB,Maurits NM

更新日期：2009-05-13 00:00:00

abstract：:Short-latency afferent inhibition (SAI) and long-latency afferent inhibition (LAI) are well-known transcranial magnetic stimulation (TMS) paradigms used to probe the sensorimotor system. To date, there is a paucity of research examining the reliability of these neurophysiological measures. This information is required...

journal_title：Brain research

authors： Turco CV,Pesevski A,McNicholas PD,Beaulieu LD,Nelson AJ

更新日期：2019-11-15 00:00:00

abstract：:The effect of aging on delta opioid receptors was examined in the brains of guinea pigs aged 1, 6, 24 and 36 months. Quantitative autoradiography was used to monitor the concentrations of delta receptors in various anatomical regions at five rostro-caudal levels. delta opioid receptor populations were found to be rema...

journal_title：Brain research

authors： Hiller JM,Fan LQ,Simon EJ

更新日期：1993-06-18 00:00:00

abstract：:Distribution of somatostatin (SS) immunoreactivity was observed in the preoptic-anterior hypothalamus (PO-AH) of the female rat brain. Six specific rabbit antibodies A (SS-14), B (SS-28), C (SS-28 complete), D (SS 14 and SS-28 both), E (SS preprohormone) and F (GHRH) were used for immunostaining using Avidin-Biotin Co...

journal_title：Brain research

authors： Bhatnagar M

更新日期：2001-05-11 00:00:00