GABA- and glycine-induced Cl- channels in cultured mouse spinal neurons require the same energy to close.

abstract：:The modulation of serotonin (5-HT) release by opioid receptors in the hippocampus of the awake, unrestrained rat was evaluated by use of in vivo microdialysis. The hippocampus was perfused with Ringer's solution (2 microliters/min), and extracellular levels of 5-HT and its major metabolite, 5-hydroxyindoleacetic acid ...

journal_title：Brain research

authors： Yoshioka M,Matsumoto M,Togashi H,Smith CB,Saito H

更新日期：1993-06-04 00:00:00

abstract：:Monoamine uptake inhibitors block the neurotoxic effects of methamphetamine (MA) upon dopaminergic and serotonergic neurons in the rat. The neurotoxic effects of MA upon dopaminergic neurons have previously been suggested to be mediated via formation of 6-hydroxydopamine (6-OHDA) from endogenous stores of dopamine (DA...

journal_title：Brain research

authors： Marek GJ,Vosmer G,Seiden LS

更新日期：1990-05-14 00:00:00

abstract：:The alpha-2 adrenergic agonist dexmedetomidine (Dex), 3-300 microg/kg, i.p., decreased cerebellar cGMP in a dose-dependent manner. Fentanyl (F), an opioid agonist, increased cerebellar cGMP at 0.3 mg/kg, s.c., and decreased it at doses >/=1 mg/kg. The inhibitory effect was receptor specific, that of Dex being blocked ...

journal_title：Brain research

authors： Vulliemoz Y,Virag L,Whittington RA

更新日期：1998-11-30 00:00:00

abstract：:The effects of 17 beta-estradiol benzoate (EB), ethynodioldiacetate and ovine prolactin on dopamine (DA) turnover have been studied. As an index for a change in turnover, differences in DA depletion following tyrosine hydroxylase inhibition with alpha-methyl-tyrosine methylester were observed. DA was measured by means...

journal_title：Brain research

authors： Wiesel FA,Fuxe K,Hökfelt T,Agnati LF

更新日期：1978-06-16 00:00:00

abstract：:Using a well-established model of binge-like ethanol treatment of rat pups on postnatal days (PD) 4-9, we found that maturation of GABAA receptor (GABAAR) miniature postsynaptic currents (mPSCs) was substantially blunted for medial septum/diagonal band (MS/DB) neurons in brain slices on PD 11-16. Ethanol reduced mPSC ...

journal_title：Brain research

authors： Wang H,DuBois DW,Tobery AN,Griffith WH,Brandt P,Frye GD

更新日期：2013-07-03 00:00:00

abstract：:It was previously proposed that norepinephrine (NE)-containing nerve terminals in visual cortex are important for the maintenance of cortical plasticity. Observations at that time indicated that local microperfusion of exogenous NE for 1 week directly into kitten visual cortex, with no alteration of the visual environ...

journal_title：Brain research

authors： Kuppermann BD,Kasamatsu T

更新日期：1984-06-04 00:00:00

abstract：:Baclofen-sensitive GABAB receptor binding to various brain regions was compared in age-matched spontaneously hypertensive (SHR) and normotensive Wistar-Kyoto (WKY) rat. The specific [3H]baclofen binding was significantly higher in SHR cerebellum, hippocampus and nucleus tractus solitarii (NTS), but lower in medulla, w...

journal_title：Brain research

authors： Singh R,Ticku MK

更新日期：1985-12-09 00:00:00

abstract：:We report here the in vivo effects of estrogen (E2) on modulation of synaptic plasticity and the agonistic (estrogen-like) role of selective estrogen receptor modulator (SERM), tamoxifen (TAM) in the CA1 of the rat hippocampus. Effects on synaptophysin (SYP), a presynaptic vesicular protein, and phosphorylated cyclic ...

journal_title：Brain research

authors： Sharma K,Mehra RD,Dhar P,Vij U

更新日期：2007-02-09 00:00:00

abstract：:Afferent pathways innervating the urinary bladder consist of myelinated Adelta- and unmyelinated C-fibers, the neuronal cell bodies of which correspond to medium and small-sized cell populations of dorsal root ganglion (DRG) neurons, respectively. Since hyperpolarization-activated cyclic nucleotide-gated cation (HCN) ...

journal_title：Brain research

authors： Matsuyoshi H,Masuda N,Chancellor MB,Erickson VL,Hirao Y,de Groat WC,Wanaka A,Yoshimura N

更新日期：2006-11-13 00:00:00

abstract：:Our previous studies have shown that there is a lower cGMP concentration in the aged brain as well as an alteration in the activity of cGMP-hydrolyzing phosphodiesterases (PDEs) and nitric oxide synthase (NOS). The aim of this study was to investigate the effect of specific inhibitors of selected PDEs on object recogn...

journal_title：Brain research

authors： Domek-Łopacińska K,Strosznajder JB

更新日期：2008-06-24 00:00:00

abstract：:Diabetes mellitus can lead to functional and structural deficits in both the peripheral and central nervous system. The pathogenesis of these deficits is multifactorial, probably involving, among others, microvascular dysfunction and alterations in intracellular calcium homeostasis. The present study examined the effe...

journal_title：Brain research

authors： Biessels GJ,ter Laak MP,Kamal A,Gispen WH

更新日期：2005-02-21 00:00:00

abstract：:Synaptic glomeruli in the nucleus submedius of the rat are described and the source of some of the component terminals identified. The glomeruli consist of large terminals with round synaptic vesicles establishing Gray type I contacts with dendrites and surrounded by layers of astrocyte derived membranes. The astrocyt...

journal_title：Brain research

authors： Ma W,Ohara PT

更新日期：1987-07-14 00:00:00

abstract：:(1) The possibility that water intake elicited by the administration of angiotensin-II to the preoptic region (POA), subfornical organ and anterior third ventricle is mediated by separate neural systems was investigated in 58 male Wistar rats using electrolytic lesion techniques. (2) Lesions of the midlateral hypothal...

journal_title：Brain research

authors： Kucharczyk J,Assaf SY,Mogenson GJ

更新日期：1976-05-28 00:00:00

abstract：:alpha-Motoneurons innervating the triceps surae and short plantar muscles were stained intracellularly with horseradish peroxidase (HRP) in 0-44-day-old kittens and adult cats. The terminal arborizations of the recurrent axon collaterals in the spinal cord were studied in the light microscope (LM). The short plantar m...

journal_title：Brain research

authors： Cullheim S,Ulfhak B

更新日期：1985-01-01 00:00:00

abstract：:This study examined whether baseline PPI levels reflect individual efficiency in tasks associated with routine versus supervisory attentional systems (SAS). PPI and neuropsychological data were collected from 30 healthy male subjects. High PPI was associated with shorter movement times on the 5-choice Reaction Time an...

journal_title：Brain research

authors： Giakoumaki SG,Bitsios P,Frangou S

更新日期：2006-03-17 00:00:00

abstract：:Glucocorticoids exacerbate aging-induced cell death, but relatively little is known about other CNS effects in senescence. We examined noradrenergic/adenylyl cyclase signaling in the cerebellum, which is a brain region that is susceptible to deterioration of synaptic function in aging. Aged control rats had increased ...

journal_title：Brain research

authors： Slotkin TA,Zhang J,McCook EC,Seidler FJ

更新日期：1998-08-03 00:00:00

abstract：:Brain-derived neurotrophic factor (BDNF) expression changes in the dorsal root ganglion (DRG) and spinal cord in some pain models. Recently, rat BDNF transcripts containing novel 5' untranslated exons were identified and characterized, and a new numbering system for rat BDNF exons was introduced. We examined the expre...

journal_title：Brain research

authors： Kobayashi H,Yokoyama M,Matsuoka Y,Omori M,Itano Y,Kaku R,Morita K,Ichikawa H

更新日期：2008-04-24 00:00:00

abstract：:Recent studies have supported the existence of projections to the paraventricular and supraoptic nuclei of the hypothalamus that arise from non-catecholaminergic neurons in the nucleus of the solitary tract, whose terminal distribution is suggestive of interactions with both parvocellular and magnocellular neurosecret...

journal_title：Brain research

authors： Sawchenko PE,Pfeiffer SW

更新日期：1995-10-02 00:00:00

abstract：:Phenylethanolamine N-methyltransferase (PNMT) activity was measured in adrenal glands and medulla oblongata from 4 inbred rat strains, Fischer 344, Buffalo, Lewis and Sprague-Dawley rats. Adrenal enzyme activity was markedly different among the strains with the highest in Fischer, followed by Sprague-Dawley, Lewis and...

journal_title：Brain research

authors： Park DH,Ehrlich M,Evinger MJ,Joh TH

更新日期：1986-04-30 00:00:00

abstract：:The effect of microinfusions of cholecystokinin octapeptide (CCK8) and its antagonist L364,718 on duodenal and jejunal motility were evaluated by electromyography in fasted and fed rats. The rats were chronically fitted with electrodes implanted on the duodeno-jejunal wall. Steel cannulas were placed bilaterally in ei...

journal_title：Brain research

authors： Liberge M,Arruebo P,Bueno L

更新日期：1990-01-29 00:00:00

abstract：:By use of the push-pull perfusion technique, release of neuronal cholecystokinin-like immunoreactivity (CCK-LI) from hypothalamus of owl monkeys was investigated in relation to an intragastric meal. In overnight fasted, halothane-anesthetized owl monkeys, levels of CCK-LI in the hypothalamic push-pull perfusate were b...

journal_title：Brain research

authors： Schick RR,Reilly WM,Roddy DR,Yaksh TL,Go VL

更新日期：1987-08-18 00:00:00

abstract：:The hippocampal formation is a highly plastic brain region that is sensitive to stress. It receives extensive noradrenergic projections, and noradrenaline is released in the hippocampus in response to stressor exposure. The hippocampus expresses particularly high levels of the alpha(1D) adrenergic receptor (ADR) and w...

journal_title：Brain research

authors： Campeau S,Nyhuis TJ,Kryskow EM,Masini CV,Babb JA,Sasse SK,Greenwood BN,Fleshner M,Day HE

更新日期：2010-04-06 00:00:00

abstract：:Lesions of the anterior hypothalamus-medial preoptic area (AH-MPOA) impair courtship and copulatory behavior in male Cnemidophorus inornatus, a sexually reproducing species of whiptail lizard, and male-like pseudosexual behaviors in C. uniparens, an all-female species. These results suggest that, since C. inornatus is...

journal_title：Brain research

authors： Kingston PA,Crews D

更新日期：1994-04-18 00:00:00

abstract：:Immunohistochemical and neuronal tracing methods were used in cats to determine which type of postganglionic sympathetic neuron is innervated by preganglionic neurons which contain corticotrophin releasing factor-like immunoreactivity (CRF-LI). Preganglionic neurons with CRF-LI have their cell bodies at two restricted...

journal_title：Brain research

authors： Shafton AD,Oldfield BJ,McAllen RM

更新日期：1992-12-25 00:00:00

abstract：:Whole-cell patch recordings of neurons in the rostral (gustatory) nucleus tractus solitarius (rNTS) were performed in a brain slice preparation from rat medulla. Neural responses to brief applications (10-45 s) of substance P (SP), via a constant superfusion apparatus, were recorded. SP transiently depolarized 80 of 1...

journal_title：Brain research

authors： King MS,Wang L,Bradley RM

更新日期：1993-08-13 00:00:00

abstract：:Dynamic microvascular remodeling maintains an optimal continuous supply of oxygen and nutrients to the brain to account for prolonged environmental variations. The objective of this study was to determine the relative time course of capillary regression during re-oxygenation after exposure to prolonged moderate hypoxi...

journal_title：Brain research

authors： Benderro GF,LaManna JC

更新日期：2014-06-20 00:00:00

abstract：:The present study examined whether the inhibition of serotonin transporters (SERT) contributes to cocaine- and other local anesthetics-induced convulsions, and which subtypes of 5-HT receptor are involved in the convulsions. For this purpose, cocaine, meprylcaine and lidocaine, all of which have different effects on S...

journal_title：Brain research

authors： Morita K,Hamamoto M,Arai S,Kitayama S,Irifune M,Kawahara M,Kihira K,Dohi T

更新日期：2005-09-28 00:00:00

abstract：:Mice pretreated with the benzodiazepine antagonist, CGS 8216 (2.5, 10, or 40 mg/kg, i.p.) learned a T-maze discrimination to a fixed performance criterion more rapidly than vehicle-treated mice. In retention tests conducted one week later, the drug-treated groups had better first-trial recall and greater difficulty re...

journal_title：Brain research

authors： Kumar BA,Forster MJ,Lal H

更新日期：1988-09-13 00:00:00

abstract：:The effects of apamin on rat locus coeruleus (LC) neurons were studied in a brain slice preparation with intracellular recording. Bath application of apamin (2-500 nM) reduced the amplitude of an intermediate component of the afterhyperpolarization (AHP) following single spontaneous action potentials, but did not chan...

journal_title：Brain research

authors： Osmanović SS,Shefner SA,Brodie MS

更新日期：1990-10-22 00:00:00

abstract：:The effect of aging on delta opioid receptors was examined in the brains of guinea pigs aged 1, 6, 24 and 36 months. Quantitative autoradiography was used to monitor the concentrations of delta receptors in various anatomical regions at five rostro-caudal levels. delta opioid receptor populations were found to be rema...

journal_title：Brain research

authors： Hiller JM,Fan LQ,Simon EJ

更新日期：1993-06-18 00:00:00