Thalamic reticular nucleus: anatomical evidence that cortico-reticular axons establish monosynaptic contact with reticulo-geniculate projection cells.

abstract：:In the present experiment we use a rat model of traumatic brain injury to evaluate the ability of low-pressure hyperbaric oxygen therapy (HBOT) to improve behavioral and neurobiological outcomes. The study employed an adaptation of the focal cortical contusion model. 64 Male Long-Evans rats received unilateral cortica...

journal_title：Brain research

authors： Harch PG,Kriedt C,Van Meter KW,Sutherland RJ

更新日期：2007-10-12 00:00:00

abstract：:The interaction of glutamatergic and dopamine neurotransmission is thought to have relevance to both the pathophysiology and pharmacotherapy of schizophrenia. For example, subanesthetic doses of the N-methyl-D-aspartate receptor (NMDA-R) antagonist ketamine induce schizophrenia-like behavioral effects in humans and bo...

journal_title：Brain research

authors： Miyamoto S,Mailman RB,Lieberman JA,Duncan GE

更新日期：2001-03-16 00:00:00

abstract：:Intraperitoneal (i.p.) administration of sulfated CCK octapeptide (CCK-8S) has been shown to induce changes in neuronal activity in the nucleus of the solitary tract (NTS) and area postrema (AP), sensory parts of the dorsal vagal complex (DVC), and in the paraventricular nucleus of the hypothalamus (PVN), as determine...

journal_title：Brain research

authors： Mönnikes H,Lauer G,Arnold R

更新日期：1997-10-03 00:00:00

abstract：:Dendrites were transected 100 microns from nerve cell somata. The probability of cell survival increased as a function of the extent of proximal segment retraction. The retraction effect is probably the result of increased resistance to calcium and sodium currents at the lesion. It is speculated that limitation of ner...

journal_title：Brain research

authors： Lucas JH

更新日期：1987-11-10 00:00:00

abstract：:As a first step in understanding the function of the 68-kDa Alz-50 antigen (A68) in the pathophysiology of Alzheimer's disease (AD), we have reexamined preliminary observations in our laboratory (Wolozin and Davies, 1986) of a protein kinase activity associated with crude preparations of the protein. This study was un...

journal_title：Brain research

authors： Vincent IJ,Davies P

更新日期：1990-10-29 00:00:00

abstract：:To investigate the role of the amygdala in central regulation of pancreatic exocrine secretion, the effects of electrolytic lesions on pancreatic secretion were studied in rats. Small bilateral electrolytic lesions in amygdaloid body restricted to basolateral, medial and central nuclei were produced. Eight days after ...

journal_title：Brain research

authors： Mine K,Tsuruta N,Nakai Y,Kataoka Y,Fujiwara M,Ueki S,Nakagawa T

更新日期：1985-08-05 00:00:00

abstract：:The dopamine-releasing and depleting substance amphetamine (AMPH) can make cortical neurons susceptible to damage, and the prevention of hyperthermia, seizures and stroke is thought to block these effects. Here we report a 2-day AMPH treatment paradigm which affected only interneurons in three cortical regions with av...

journal_title：Brain research

authors： Jakab RL,Bowyer JF

更新日期：2002-12-20 00:00:00

abstract：:We have attempted to identify some novel genes which were found to be more highly expressed in the embryonic brain than in the adult brain. Consequently, one of these clones was identified as alpha-globin cDNA. Actually, alpha-globin mRNA was detected in the neurons. In addition, beta-globin mRNA was detected in the n...

journal_title：Brain research

authors： Ohyagi Y,Yamada T,Goto I

更新日期：1994-01-28 00:00:00

abstract：:Focal cerebral ischemia elicits an inflammatory response characterized by the infiltration and accumulation of leukocytes, as well as the secretion of inflammatory mediators (Clark et al., Brain Res. Bull., 35 (1994) 387-392; Garcia et al., Am. J. Pathol., 144 (1994) 188-199; Wang et al., J. Neurochem. 71 (1998) 1194-...

journal_title：Brain research

authors： Che X,Ye W,Panga L,Wu DC,Yang GY

更新日期：2001-06-01 00:00:00

abstract：:gamma-L-Glutamyl-L-aspartic acid (gamma-LGLA) has been isolated from Datura stramonium; its structure has been determined and it was then synthesized. In male Swiss mice intraperitoneal administration of the natural peptide (125 nmol/kg) or of the synthetic peptide (25-2500 nmol/kg) 24 h after acquisition of a Y-maze ...

journal_title：Brain research

authors： Ungerer A,Schmitz-Bourgeois M,Mélan C,Boulanger Y,Reinbolt J,Amiri I,de Barry J

更新日期：1988-04-19 00:00:00

abstract：:Astrogliogenesis in the human fetal cerebellum was examined in 46 cerebella obtained from hysterotomy specimens ranging between 9 and 20 weeks of ovulation age. By correlating the results obtained by rapid Golgi and Golgi-Cox methods, the indirect immunofluorescence technique for glial fibrillary acidic protein, and e...

journal_title：Brain research

authors： Choi BH,Lapham LW

更新日期：1980-05-26 00:00:00

abstract：:To investigate whether a task rule carried over from the preceding trial modifies an early portion of the stimulus-locked lateralized readiness potential (sLRP), participants were asked to perform two different flanker tasks that were switched. One task required a left-hand response for a central letter "H" in a five-...

journal_title：Brain research

authors： Umebayashi K,Okita T

更新日期：2010-07-30 00:00:00

abstract：:The current study explored the effects of prolonged antidepressant treatment on mRNA levels of two nuclear receptors in specific brain regions of an animal model of depression, the Wistar-Kyoto (WKY) rat. Both nuclear receptors have been implicated in the development or treatment of depression. The expression of nucle...

journal_title：Brain research

authors： Schaffer DJ,Tunc-Ozcan E,Shukla PK,Volenec A,Redei EE

更新日期：2010-11-29 00:00:00

abstract：:To determine the effect of thyroid hormones (TH) on cerebral tissue malondialdehyde (MDA) content and accumulation of MDA-bound proteins, hyperthyroid rats and hypothyroid rats were compared to euthyroid controls. Hyperthyroidism was induced by daily injection of l-3,5, 3'-triiodothyronine (15 ug (100 g)-1) intraperit...

journal_title：Brain research

authors： Chehade J,Kim J,Pinnas JL,Mooradian AD

更新日期：1999-05-22 00:00:00

abstract：:Compound action potential recording techniques were used to investigate the time- and frequency-dependent effects of 4-aminopyridine (4-AP) and tetraethylammonium (TEA) on large diameter, fast conducting (t1) and medium diameter, middle conducting (t2) optic tract axons in anesthetized hooded rats. Single-pulse studie...

journal_title：Brain research

authors： Fox DA,Ruan DY

更新日期：1989-10-02 00:00:00

abstract：:Behavioral studies have shown that the hyperalgesia arising from inflammatory agents, such as prostaglandin E(2) (PGE(2)), can be antagonized by activators of the ATP-sensitive potassium current (K(ATP)). This observation raises questions as to whether this suppression results from a direct action on sensory neurons a...

journal_title：Brain research

authors： Chi XX,Jiang X,Nicol GD

更新日期：2007-05-11 00:00:00

abstract：:Brains of reptiles, Caiman crocodilus, were processed by standard immunocytochemical methodology using a polyclonal antibody to gamma-aminobutyric acid (GABA) raised in rabbit and a polyclonal antibody to glutamic acid decarboxylase (GAD) raised in sheep. No GABA(+) or GAD(+) cells or puncta were observed over any tha...

journal_title：Brain research

authors： Pritz MB,Stritzel ME

更新日期：1988-08-02 00:00:00

abstract：:Brain iron overload has a detrimental role in brain injury after intracerebral hemorrhage (ICH). Lipocalin 2 (LCN2), a siderophore-binding protein, is involved in cellular iron transport. The present study investigated changes in LCN2 expression after ICH and the role of iron in those changes. Male Sprague-Dawley rats...

journal_title：Brain research

authors： Dong M,Xi G,Keep RF,Hua Y

更新日期：2013-04-10 00:00:00

abstract：:The physiological role of amyloid precursor protein (APP), whose anomalous metabolite is a putative pathogen for Alzheimer disease, remains unclear. From the enhanced responsiveness to glutamate in cultured hippocampal neurons after the introduction of cDNA of APP695 (an isoform of APP dominant in human brain) using a...

journal_title：Brain research

authors： Tominaga-Yoshino K,Uetsuki T,Yoshikawa K,Ogura A

更新日期：2001-11-09 00:00:00

abstract：:Hippocampal neurogenesis plays a very important role in learning and memory functions. In a search for best neurological drugs that protect neuronal cells and stimulate neurogenesis with no side effects, cannabinoids proved to be a strong group of substances having many beneficial properties. The aim of this study was...

journal_title：Brain research

authors： Andres-Mach M,Haratym-Maj A,Zagaja M,Rola R,Maj M,Chrościńska-Krawczyk M,Luszczki JJ

更新日期：2015-10-22 00:00:00

abstract：:We have developed a novel imaging system "real-time bioradiography", which is able to estimate the dynamic changes of physiological function and metabolism in living tissues using positron emitter-labeled tracers and chemiluminescence probes. The apparatus is comprised of a photon-counting camera, image-controller, cu...

journal_title：Brain research

authors： Sasaki T,Iwamoto A,Tsuboi H,Watanabe Y

更新日期：2006-03-10 00:00:00

abstract：:A special feature of the extracellular matrix in adult brains of various species is the concentration of certain components around different sub-populations of neurones, giving rise to net-like structures termed perineuronal nets. Recently, some of these components have been identified but the function of these nets h...

journal_title：Brain research

authors： Haunso A,Celio MR,Margolis RK,Menoud PA

更新日期：1999-07-10 00:00:00

abstract：:The regulation of circadian rhythms changes with age. In humans, changes in the timing of sleep and wakefulness are especially common. In Syrian hamsters Mesocricetus auratus the free running period of the activity/rest rhythm shortens with age. The present study tested the hypothesis that critical age-related changes...

journal_title：Brain research

authors： Viswanathan N,Davis FC

更新日期：1995-07-17 00:00:00

abstract：:The chronic dietary intake of essential polyunsaturated fatty acids (PUFAs) can modulate learning and memory by being incorporated into neuronal plasma membranes. Representatives of two PUFA families, the n-3 and n-6 types become integrated into membrane phospholipids, where the actual (n-6)/(n-3) ratio can determine ...

journal_title：Brain research

authors： Farkas E,de Wilde MC,Kiliaan AJ,Meijer J,Keijser JN,Luiten PG

更新日期：2002-11-01 00:00:00

abstract：:The localization of a GTP-binding protein (G(o)) in the cerebellar and cerebral cortex and hippocampus of the normal and reeler mutant mouse was immunohistochemically examined using affinity-purified antibody raised against the alpha subunit of G(o). Although the general distribution pattern of G(o)-immunoreactive pro...

journal_title：Brain research

authors： Terashima T,Katada T,Ichikawa R,Ui M,Inoue Y

更新日期：1993-01-22 00:00:00

abstract：:Mechanisms regulating sexual differentiation of the zebra finch song system appear to include both genetic and hormonal factors. Sorting Nexin 2 (SNX2), which is involved in trafficking proteins between cellular membranes, and androgen receptor (AR) mRNA are both increased in song control nuclei of juvenile males comp...

journal_title：Brain research

authors： Wu D,Tang YP,Wade J

更新日期：2010-07-09 00:00:00

abstract：:The bag cell neurons of Aplysia are capable of generating an afterdischarge, which, in vivo, triggers egg-laying behavior. Pharmacologic elevation of cyclic AMP levels in isolated bag cell neurons has been shown to initiate repetitive firming similar to that seen during an afterdischarge, and to decrease outward curre...

journal_title：Brain research

authors： Loechner KJ,Kaczmarek LK

更新日期：1990-11-05 00:00:00

abstract：:The firing patterns of up to 4 concurrently active masseter motor units were studied with intramuscular electrodes during a continuous isometric contraction of 15 min duration, in which the subject maintained the mean firing rate of one selected unit at 10 Hz. With this paradigm the net excitation (i.e. mean firing ra...

journal_title：Brain research

authors： Nordstrom MA,Miles TS

更新日期：1991-05-24 00:00:00

abstract：:Biochemical analysis of the binding of [125I]Bolton-Hunter coupled substance P [( 125I]BH-SP) to slide-mounted sections of rat brain demonstrated that [125I]BH-SP labels a binding site with a structure-activity profile characteristic of a substance P receptor. Under optimized preincubation and incubation conditions, t...

journal_title：Brain research

authors： Rothman RB,Herkenham M,Pert CB,Liang T,Cascieri MA

更新日期：1984-08-20 00:00:00

abstract：:The effects of 5-hydroxytryptamine (5-HT) on lateral horn cells contained in thin in vitro slices of neonatal rat spinal cord were investigated by means of intracellular recording techniques. Superfusion of 5-HT (1-100 microM) to lateral horn cells caused a concentration-dependent membrane depolarization leading to, i...

journal_title：Brain research

authors： Ma RC,Dun NJ

更新日期：1986-01-01 00:00:00