Abstract：
:This study shows that in the choroid plexus of Rana esculenta particulate guanylate cyclase (GC) is appreciably stimulated by porcine brain natriuretic peptide (BNP). Ultracytochemical tests for GC show that BNP notably increases the enzymatic reaction product along the apical surfaces of the epithelial cells. It can therefore be hypothesized that the apical zone of the epithelial cells possess receptors which have a particular affinity for BNP produced in the central nervous system and dumped into the cerebrospinal fluid. These results, together with those of a previous study [32], confirm that the choroid plexus is an organ which has receptors for the natriuretic peptides which are involved in the processes of osmoregulation and the control of cerebrospinal fluid production.
journal_name
Brain Resjournal_title
Brain researchauthors
Vagnetti D,Tei S,Secca T,Santarella B,Roscani C,Farnesi RMdoi
10.1016/0006-8993(95)01178-1subject
Has Abstractpub_date
1995-12-24 00:00:00pages
295-301issue
1-2eissn
0006-8993issn
1872-6240pii
0006-8993(95)01178-1journal_volume
705pub_type
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