Abstract：
:The non-cholinergic excitatory potential elicited in neurons of the isolated inferior mesenteric ganglia was depressed by bath application of Met- or Leu-enkephalin and enhanced by naloxone or naltrexone. The membrane depolarization induced by exogenously applied putative transmitter substance P was not appreciably affected by either enkephalin (Enk) or opiate antagonists. Our results indicate that the non-cholinergic excitatory transmission which may be mediated by substance P in prevertebral ganglia is modulated presynaptically by endogenously released Enk in a manner that may resemble the interaction between these two peptides in the spinal cord.
journal_name
Brain Resjournal_title
Brain researchauthors
Jiang ZG,Simmons MA,Dun NJdoi
10.1016/0006-8993(82)90211-6subject
Has Abstractpub_date
1982-03-04 00:00:00pages
185-91issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(82)90211-6journal_volume
235pub_type
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