Ornithine decarboxylase activity in rat intestinal mucosa and liver is stimulated by central administration of 2-deoxy-D-glucose but not of 2,5-anhydro-D-mannitol.

abstract：:The periaqueductal gray matter (PAG) has been implicated in a variety of different functions, including autonomic regulation. Chemical stimulation of the lateral PAG produces hypertension and tachycardia while activation of the ventrolateral PAG produces the opposite effect. While these effects are the result of alter...

journal_title：Brain research

authors： Farkas E,Jansen AS,Loewy AD

更新日期：1997-08-01 00:00:00

abstract：:Nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d) containing fibers and neurons within the hippocampal formation and entorhinal cortex of the new world monkey were determined using a direct histochemical procedure. Occasional intensely stained bipolar NADPH-d positive neurons were seen in the polymorphi...

journal_title：Brain research

authors： Mufson EJ,Brady DR,Carey RG

更新日期：1990-05-21 00:00:00

abstract：:Seizure is a common acute and severe disease in infants and children. Recurrent seizures or persistent seizures may cause irreversible brain damage. Mitogen activated protein kinase (MAPK) signaling pathway is associated with an inflammatory response, however it's involvement in the pathological process of seizures is...

journal_title：Brain research

authors： Hu QP,Huang XY,Peng F,Yang H,Wu C

更新日期：2020-10-15 00:00:00

abstract：:Adenosine, agmatine and kynurenic acid are endogenous ligands acting on different (e.g. adenosine, NMDA, alpha(2)-adrenergic and imidazoline) receptors with a potential role in nociception at the spinal level. Their antinociceptive effects have already been investigated as monotherapy, but only a few studies have repo...

journal_title：Brain research

authors： Kekesi G,Joo G,Csullog E,Peter-Szabo M,Benedek G,Horvath G

更新日期：2004-12-10 00:00:00

abstract：:The effects of the epileptogenic agent, penicillin, on excitatory and inhibitory postsynaptic potentials (EPSPs and IPSPs) were studied in the hippocampal in vitro slice preparation. The actions of penicillin were compared to those of bicuculline, an antagonist of gamma-aminobutyric acid. Neither substance enhanced mo...

journal_title：Brain research

authors： Schwartzkroin PA,Prince DA

更新日期：1980-02-03 00:00:00

abstract：:Determining the mechanism by which fluorescent retrograde neuronal tracers are taken up requires knowledge of their composition. It has been claimed that Fluoro-Gold, a retrogradely transported fluorescent neuronal tracer, is 2-hydroxy-4,4'-diamidinostilbene (hydroxystilbamidine), an amidine antibiotic. However, this ...

journal_title：Brain research

authors： Wessendorf MW

更新日期：1991-07-05 00:00:00

abstract：:Rats reared on a diet in which choline is replaced with N-aminodeanol (NADE), undergo > 50% replacement of brain acetylcholine with acetylated NADE, a false cholinergic transmitter. We examined amounts of sleep and wakefulness in 7 littermate pairs of rats fed either NADE-substituted, or a choline control diet for > 1...

journal_title：Brain research

authors： Szymusiak R,McGinty D,Fairchild MD,Jenden DJ

更新日期：1993-11-26 00:00:00

abstract：:To examine the effect of development on rabbit brain insulin and insulin-like growth factor (IGF) receptor expression, we characterized and quantitated receptor mRNAs by Northern blot analysis and affinity-labeled ligand bound receptors by SDS-PAGE and autoradiography. At various stages of development ranging from 23 ...

journal_title：Brain research

authors： Devaskar SU,Sadiq HF,Holtzclaw L,George M

更新日期：1993-03-05 00:00:00

abstract：:Olfactory bulbectomy (OBX) in rodents induces neurochemical and behavioral changes similar to those observed in individuals with depressive disorders. Our previous study suggested that OBX alters dopaminergic function in the striatum of mice; however, the effects on dopaminergic function in the hypothalamus is unknown...

journal_title：Brain research

authors： Takahashi K,Nakagawasai O,Nakajima T,Okubo M,Nishimura Y,Sakuma W,Yamagata R,Nemoto W,Miyagawa K,Kurokawa K,Mochida-Saito A,Tsuji M,Takeda H,Tadano T,Tan-No K

更新日期：2020-11-01 00:00:00

abstract：:Brain-derived neurotrophic factor (BDNF) is a family of neurotrophins that plays crucial roles in neural development, survival, maintenance and regeneration both in central and peripheral nervous systems. To examine the effects of BDNF on mastication, jaw movement trajectories and masticatory muscle activities were el...

journal_title：Brain research

authors： Okayasu I,Yamada Y,Maeda T,Yoshida N,Koga Y,Oi K

更新日期：2004-07-30 00:00:00

abstract：:It has been hypothesized that mitochondrial respiratory chain dysfunction leads to a pyrimidine deficiency since the pyrimidine biosynthetic enzyme dihydroorotate dehydrogenase is coupled to the electron transport chain. The uridine prodrug triacetyluridine (PN401) is neuroprotective in several models of neurodegenera...

journal_title：Brain research

authors： Garcia RA,Liu L,Hu Z,Gonzalez A,von Borstel RW,Saydoff JA

更新日期：2005-12-20 00:00:00

abstract：:Body temperature changes and heat shock protein (HSP-72) induction in the caudate nucleus were studied in female C57BL/6N mice pretreated with ibogaine (50 mg/kg) and sacrificed 48 h. after a single dose of methamphetamine (20 mg/kg). Methamphetamine injection resulted in hyperthermia and induced HSP-72 expression, wh...

journal_title：Brain research

authors： Yu X,Imam SZ,Newport GD,Slikker W Jr,Ali SF

更新日期：1999-03-27 00:00:00

abstract：:Anisomycin is both a well-established protein synthesis inhibitor and a potent activator of the p38/JNK MAPK pathway. It has been used to block the late phase of long-term potentiation (LTP) and long-term depression (LTD) in hippocampus. In this study, we have found that anisomycin produces a time-dependent decline in...

journal_title：Brain research

authors： Xiong W,Kojic LZ,Zhang L,Prasad SS,Douglas R,Wang Y,Cynader MS

更新日期：2006-04-26 00:00:00

abstract：:The possibility of retinotopic organization of pathways of retinal fibers within the optic tract and the tectum of the frog was studied by selective labeling of the retinal fibers with horseradish peroxidase. Within the optic tract the pathways of the ventral, temporal and dorsal retinal fibers were ordered from the d...

journal_title：Brain research

authors： Fujisawa H,Watanabe K,Tani N,Ibata Y

更新日期：1981-02-09 00:00:00

abstract：:Lithium is detected in the mouse brain with the aid of a (n,alpha) nuclear reaction. The resolving power is of a few micron. The detection efficiency is estimated in a first series of experiments with brain sections of progressively increasing thickness. This allows us to make the microlocation of lithium in the brain...

journal_title：Brain research

authors： Thellier M,Heurteaux C,Wissocq JC

更新日期：1980-10-13 00:00:00

abstract：:The purpose of the present investigation was to record electrophysiological responses from single fibers in the hamster superior laryngeal nerve (SLN) that were responsive to chemical stimulation of the larynx. Twenty chemical solutions, commonly used in studies of mammalian gustatory physiology, were applied to taste...

journal_title：Brain research

authors： Dickman JD,Smith DV

更新日期：1988-05-31 00:00:00

abstract：:The mitochondrial respiratory chain is a powerful source of reactive oxygen species (ROS) also in noise induced hearing loss (NIHL) and anti-oxidants and free-radicals scavengers have been shown to attenuate the damage. Coenzyme Q(10) (CoQ(10)) or ubiquinone has a bioenergetic role as a component of the mithocondrial ...

journal_title：Brain research

authors： Fetoni AR,Piacentini R,Fiorita A,Paludetti G,Troiani D

更新日期：2009-02-27 00:00:00

abstract：:Female golden-mantled ground squirrels that sustained complete ablation of the suprachiasmatic nucleus (SCNx) were housed pre- and post-operatively at 23 degrees C and then at 6.5 degrees C for 5-7 yr. SCNx and control animals held at the higher temperature manifested circannual rhythms (CARs) in body mass. In contras...

journal_title：Brain research

authors： Ruby NF,Dark J,Heller HC,Zucker I

更新日期：1998-01-26 00:00:00

abstract：:Animal models of cerebral infarction are crucial to understanding the mechanisms of neuronal survival following ischemic brain injury and to the development of therapeutic interventions for victims of all types of stroke. Rodents have been used extensively in such research. One rodent model of stroke utilizes either p...

journal_title：Brain research

authors： Duckworth EA,Butler TL,De Mesquita D,Collier SN,Collier L,Pennypacker KR

更新日期：2005-04-25 00:00:00

abstract：:Acute swim stress of mice produces increases in the density of high and low affinity binding sites in the brain for the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), together with analgesia as measured by an increase in tail flick latency. Apparent tolerance develops in repeated swimming with analgesia a...

journal_title：Brain research

authors： Skerritt JH,Trisdikoon P,Johnston GA

更新日期：1981-06-29 00:00:00

abstract：:Neurons with intrinsic pacemaker activity and presumed sympathoexcitatory function were recorded in rat tissue slices within the confines of the rostroventrolateral reticular nucleus (RVL). These cells were excited in dose-dependent fashion by arginine vasopressin (AVP, 10(8)-10(6) M) but not by oxytocin (up to 10(7) ...

journal_title：Brain research

authors： Sun MK,Guyenet PG

更新日期：1989-07-17 00:00:00

abstract：:[3H]Paroxetine binding to human brain tissue was characterized. Competition studies in the putamen and frontal cortex revealed single-site binding models for binding sensitive to 5-hydroxytryptamine (5-HT) (Ki 1-3 microM) and citalopram (Ki 0.6 nM), which displaced the same amount of binding. However, desipramine, nor...

journal_title：Brain research

authors： Bäckström I,Bergström M,Marcusson J

更新日期：1989-05-08 00:00:00

abstract：:Glioblastoma stem cells (GSCs) are thought to contribute to the diffuse invasiveness of malignant gliomas. Emerging evidence supports a role for a disintegrin and metalloproteinase 17 (ADAM17) in proteolytic ectodomain shedding of several EGFR-binding ligands, which subsequently activate PI3K/AKT and MEK/ERK pathways ...

journal_title：Brain research

authors： Chen X,Chen L,Chen J,Hu W,Gao H,Xie B,Wang X,Yin Z,Li S,Wang X

更新日期：2013-11-13 00:00:00

abstract：:Bulk-isolated human and bovine oligodendroglia, practically free from myelin, have been used in attempts to elicit an autoimmune response which has been compared with acute experimental allergic encephalomyelitis (EAE). For these experiments, a total of 20 Hartley guinea pigs, 33 Lewis rats and 16 rabbits have been st...

journal_title：Brain research

authors： Raine CS,Wiśniewski HM,Iqbal K,Grundkeiqbal I,Norton WT

更新日期：1977-01-21 00:00:00

abstract：:The mismatch negativity, an ERP that reflects the detection of change in the auditory environment, is considered to be a relatively automatic process. Its automaticity has by in large been studied using the oddball paradigm, in which a physical feature of a frequently presented standard stimulus is changed. In the pre...

journal_title：Brain research

authors： Sculthorpe LD,Collin CA,Campbell KB

更新日期：2008-10-09 00:00:00

abstract：:Glucose modulates substantia nigra (SN) dopamine (DA) neuronal activity and GABA axon terminal transmitter release by actions on an ATP-sensitive potassium channel (K(ATP)). Here, the effect of altering SN glucose levels on striatal DA release was assessed by placing microdialysis probes into both the SN and striatum ...

journal_title：Brain research

authors： Levin BE

更新日期：2000-08-25 00:00:00

abstract：:Carbonic anhydrase (CA) and cholinesterase (CE) histochemical staining of rabbit spinal nerve roots and dorsal root ganglia demonstrated that among the reactive myelinated axons, with minor exceptions, sensory axons were CA positive and CE negative whereas motor axons were CA negative and CE positive. The high specifi...

journal_title：Brain research

authors： Riley DA,Sanger JR,Matloub HS,Yousif NJ,Bain JL,Moore GH

更新日期：1988-06-21 00:00:00

abstract：:Neurophysiological responses were recorded in individual fibers of the lingual and chorda tympani nerves and in single cortical neurons in the rat in response to a battery of tactile, thermal and chemical stimuli applied to the oral cavity. Two categories of thermally sensitive units were identified. Chorda tympani fi...

journal_title：Brain research

authors： Kosar E,Schwartz GJ

更新日期：1990-04-16 00:00:00

abstract：:Phosphorylation of cyclic AMP response element binding protein (CREB) is one of the most important mechanisms controlling various gene transcriptions. In the present study, the phosphorylation of CREB was examined immunohistochemically at 24 h of recirculation following 1.5 h of middle cerebral artery occlusion (MCAO)...

journal_title：Brain research

authors： Tanaka K,Nagata E,Suzuki S,Dembo T,Nogawa S,Fukuuchi Y

更新日期：1999-02-13 00:00:00

abstract：:Treatment of castrated quail with testosterone (T) reliably activates male copulatory behavior and, at the same time, increases the aromatase activity (AA), the number of aromatase-immunoreactive (ARO-ir) cells and the concentration of aromatase mRNA as measured by RT-PCR in the brain. All these effects can be mimicke...

journal_title：Brain research

authors： Foidart A,Tlemçani O,Harada N,Abe-Dohmae S,Balthazart J

更新日期：1995-12-01 00:00:00