Abstract：
:Metabolic dysfunction in the relay nuclei of the rat vibrissa circuit follows traumatic brain injury (TBI). This study examined the effects of mild (1.4-1.5 atm) parasagittal fluid-percussion injury on the electrophysiology of this circuit. TBI caused significant reductions in slope and increases in latency of vibrissa-evoked field potentials 3 days after injury. Assessment of open-field swimming revealed an increase in thigmotaxis 2 days after injury. TBI caused mild selective cortical damage and limited axonal swelling at the injury site. Thus mild injury disrupts somatosensory electrophysiology and exploratory behavior.
journal_name
Brain Resjournal_title
Brain researchauthors
Sanders MJ,Dietrich WD,Green EJdoi
10.1016/s0006-8993(01)02424-6subject
Has Abstractpub_date
2001-06-15 00:00:00pages
141-4issue
1eissn
0006-8993issn
1872-6240pii
S0006-8993(01)02424-6journal_volume
904pub_type
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