Abstract:
:We utilized nylon arrays to measure gene expression in mouse brains after various postmortem intervals (PMIs). Gene expression after overnight refrigeration or 4 h at room temperature then overnight refrigeration correlated highly and approximately equivalently to that in brains processed immediately. After 8-24 h at room temperature and overnight refrigeration gene expression correlation and equivalency declined, but 90-95% of detected genes were within +/-40% of baseline levels. Brain homogenate pH did not change with PMI.
journal_name
Brain Resjournal_title
Brain researchauthors
Trotter SA,Brill LB 2nd,Bennett JP Jrdoi
10.1016/s0006-8993(02)02644-6subject
Has Abstractpub_date
2002-06-28 00:00:00pages
120-3issue
1-2eissn
0006-8993issn
1872-6240pii
S0006899302026446journal_volume
942pub_type
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