Increase of dendritic branching of CA3 neurons of hippocampus and self-stimulation areas in subjects experiencing self-stimulation of lateral hypothalamus and substantia nigra-ventral tegmental area.

abstract：:Cerebellum is involved in the motion coordination and working memory, to which spike programming at Purkinje neurons are essential. The development of Purkinje neurons in the embryonic stage has been well studied. However, it is not clear about the maturation of their intrinsic property related to spike programming du...

journal_title：Brain research

authors： Guan S,Ma S,Zhu Y,Wang J

更新日期：2006-06-30 00:00:00

abstract：:Corticotropin-releasing factor (CRF) in the brain plays an important role in regulations of physiological and behavioral processes, yet CRF distribution in tree shrew brain has not been thoroughly and systematically reported. Here we examined the distribution of CRF immunoreactivity in the brain of tree shrews (Tupaia...

journal_title：Brain research

authors： Shu YM,Ni RJ,Sun YJ,Fang H,Zhou JN

更新日期：2015-08-27 00:00:00

abstract：:The research question was, do events arising from rhythmic passive movement of the human leg lead to inhibition of the H reflex pathway in the stationary leg contralateral to that movement? Further, as the angular velocity of the passive movement increases, does the contralateral reflex inhibition also increase? Stabl...

journal_title：Brain research

authors： Collins DF,McIlroy WE,Brooke JD

更新日期：1993-02-12 00:00:00

abstract：:Photoreceptor outer segments are continually renewed from base to tip and consequently the membrane at the tip is older than at the base. In parallel with this, there are differences in light responsiveness, and it has been proposed that these may be due to the aforementioned differences in age. We have tested this pr...

journal_title：Brain research

authors： Leibovic KN,Bandarchi J

更新日期：1997-03-07 00:00:00

abstract：:The aim of the present study was to evaluate p38 MAPK activation following focal stroke and determine whether SB 239063, a novel second generation p38 inhibitor, would directly attenuate early neuronal injury. Following permanent middle cerebral artery occlusion (MCAO), brains were dissected into ischemic and non-isch...

journal_title：Brain research

authors： Legos JJ,Erhardt JA,White RF,Lenhard SC,Chandra S,Parsons AA,Tuma RF,Barone FC

更新日期：2001-02-16 00:00:00

abstract：:Available evidence suggests that regular, moderate-intensity exercise has beneficial effects on neural health, perhaps including neuroprotection. To evaluate this idea further, we compared the severity of kainate-induced neuronal loss in exercised versus sedentary female rats. Stereological estimations of neuron numbe...

journal_title：Brain research

authors： Ramsden M,Berchtold NC,Patrick Kesslak J,Cotman CW,Pike CJ

更新日期：2003-05-09 00:00:00

abstract：:Current and voltage clamp recordings were made with a patch-clamp technique from large, light, dorsal root ganglia (DRG) neurons in tissue culture, derived from trisomy 16 and normal fetal mice. In a Na gradient of [52 mM]o/[28 mM]i, the action potential was accelerated, depolarization and repolarization were faster a...

journal_title：Brain research

authors： Orozco CB,Epstein CJ,Rapoport SI

更新日期：1988-02-01 00:00:00

abstract：:Odor stimulation of the nose in the box turtle and the gopher tortoise produced a characteristic series of slow potentials in the olfactory bulb which were referred to as the odor evoked response. When recorded with direct coupling, the odor evoked response had 3 components: wave I, a short duration monophasic event; ...

journal_title：Brain research

authors： Beuerman RW

更新日期：1975-10-24 00:00:00

abstract：:In rat models of absence epilepsy, epileptic spike-wave discharges appeared in EEG spontaneously, and the incidence of epileptic activity increases with age. Spike-wave discharges and sleep spindles are known to share common thalamo-cortical mechanism, suggesting that absence seizures might affect some intrinsic prope...

journal_title：Brain research

authors： Sitnikova E,Hramov AE,Grubov V,Koronovsky AA

更新日期：2014-01-16 00:00:00

abstract：:While it is generally assumed that cocaine self-administration (SA) is determined and maintained by the pharmacological actions of cocaine in the brain, it is also a drug-motivated and drug-reinforced goal-directed behavior, which is determined by concurrent learning and behavioral performance. To dissociate the contr...

journal_title：Brain research

authors： Kiyatkin EA,Brown PL

更新日期：2004-04-16 00:00:00

abstract：:Gamma-hydroxybutyrate (GHB) has been shown to have therapeutical properties in various psychiatric disorders, especially in alcohol abuse, and to mimic different actions of ethanol at the cellular and system level. Using whole-cell patch-clamp recordings on brain slices of 21- to 25-day-old rats, the present study inv...

journal_title：Brain research

authors： Brancucci A,Berretta N,Mercuri NB,Francesconi W

更新日期：2004-01-30 00:00:00

abstract：:Previous electrophysiological as well as imaging research has contributed to the understanding of impairments in attention, executive functions, and memory in patients with attention-deficit/hyperactivity disorder (ADHD). However, there is a lack of studies investigating ADHD related differences in the gamma range of ...

journal_title：Brain research

authors： Lenz D,Krauel K,Schadow J,Baving L,Duzel E,Herrmann CS

更新日期：2008-10-15 00:00:00

abstract：:(1) Spreading depression (SD) could be elicited in isolated carp retina by KCI application, the concomitants of which were similar to those described in other vertebrates. (2) The threshold for generating SD was greatly reduced by brief immersion of the retina in low ci-ringer's solutions. The properties of SD waves w...

journal_title：Brain research

authors： Higashida H,Sakakibara M,Mitarai G

更新日期：1977-01-14 00:00:00

abstract：:In the present study, receptor specific compounds were infused via a microdialysis probe in the vicinity of the right locus coeruleus (LC). During the infusion of these compounds, the extracellular content of noradrenaline was recorded in the ipsilateral medial prefrontal cortex (mPFC) with a second microdialysis prob...

journal_title：Brain research

authors： Kawahara Y,Kawahara H,Westerink BH

更新日期：1999-03-27 00:00:00

abstract：:The double-labeling, fluorescent dye technique was used in order to demonstrate the extent to which the central processes of renal afferent neurons directly project to the brainstem. One injection of a fluorescent dye was placed in the cortex of the left kidney of male rats, and a second injection of a different dye w...

journal_title：Brain research

authors： Wyss JM,Donovan MK

更新日期：1984-04-23 00:00:00

abstract：:The ependymocytes lining the central canal of the spinal cord in rats have prominent F-actin networks in the apical cytoplasm, exhibiting significant regional heterogeneity between differing spinal levels. It is not clear when and how this regional heterogeneity develops. We examined F-actin in the central canal durin...

journal_title：Brain research

authors： Li YC,Bai WZ,Hashikawa T

更新日期：2008-11-06 00:00:00

abstract：:Paranodal glial loops (lateral belt cytoplasm) of myelinated CNS and PNS fibres contain tubules of agranular reticulum, as well as microtubules, wound spirally around the axon. Similar agranular elements run circumferentially in the expanded rims of sheet-like astrocytic processes encapsulating thalamic synaptic glome...

journal_title：Brain research

authors： Spacek J,Lieberman AR

更新日期：1980-09-08 00:00:00

abstract：:Intracerebroventricular (ICV) streptozotocin (STZ) treated rat has been described as a suitable model for sporadic Alzheimer's disease (AD). Central application of STZ has demonstrated behavioral and neurochemical features that resembled those found in human AD. Chronic treatments with antioxidants, acetylcholinestera...

journal_title：Brain research

authors： Ponce-Lopez T,Liy-Salmeron G,Hong E,Meneses A

更新日期：2011-12-02 00:00:00

abstract：:Neurotrophic factors (NTFs), beside regulating neuronal survival in the central and peripheral nervous system, are also involved in the modulation of neuronal function in the adult animal. Both brain-derived neurotrophic factor (BDNF) and glial cell-derived neurotrophic factor (GDNF) levels are altered in pathological...

journal_title：Brain research

authors： Ciobanu C,Reid G,Babes A

更新日期：2009-08-11 00:00:00

abstract：:Rhythmic caffeine hyperpolarizations generated in bullfrog sympathetic ganglion cells are assumed to be caused by periodic increase in gK due to rise in [Ca2+]i7--9,13. Caffeine-induced outward currents seem to be composed of two different components, which show different pharmacological natures and also different dep...

journal_title：Brain research

authors： Koketsu K,Akasu T,Miyagawa M

更新日期：1982-07-15 00:00:00

abstract：:The occurrence of hypoxia-ischemia (HI) during early fetal or neonatal stages of an individual leads to the damaging of immature neurons resulting in behavioral and psychological dysfunctions, such as motor or learning disabilities, cerebral palsy, epilepsy or even death. No effective treatment is currently available ...

journal_title：Brain research

authors： Calvert JW,Yin W,Patel M,Badr A,Mychaskiw G,Parent AD,Zhang JH

更新日期：2002-09-27 00:00:00

abstract：:The distribution of melanin-concentrating hormone-like immunoreactivity (MCH-LI) in 41 microdissected brain and spinal cord regions was determined using radioimmunoassay with antibodies to salmon MCH. The highest concentration of MCH-LI was detected just ventral to the zona incerta (subzona incerta) (2923.2 fmol/mg pr...

journal_title：Brain research

authors： Zamir N,Skofitsch G,Jacobowitz DM

更新日期：1986-05-14 00:00:00

abstract：:Vascular permeability and intravascular space in the rat cerebral cortex and hypothalamus were assessed 5 and 14 days after the production of either right or left hemisphere frontal cortical suction lesions. Rats were intravenously injected with large (dextran, 50,000 kdalton) and small (inulin, 5000 kdalton) molecula...

journal_title：Brain research

authors： Margolis RL,Robinson RG

更新日期：1985-12-16 00:00:00

abstract：:Nitric oxide (NO), a potent vasodilator and nontraditional neurotransmitter, is an important mediator of the changes in cerebral blood flow (CBF) associated with increased neuronal activity (neurovascular coupling). In the present work, we investigated the role of NO and of its newly recognized precursor, nitrite, in ...

journal_title：Brain research

authors： Piknova B,Kocharyan A,Schechter AN,Silva AC

更新日期：2011-08-17 00:00:00

abstract：:Dynamin-1 is a multi-domain GTPase that is crucial for the fission stage of synaptic vesicle recycling and vesicle trafficking. In this study, we constructed prokaryotic expression plasmids for the four functional domains of dynamin-1, which are pGEX-4T-2-PH, pGEX-4T-2-PRD, pGEX-4T-2-GED and pGEX-4T-2-GTPase. Glutathi...

journal_title：Brain research

authors： Zhang C,Omran AG,He F,Deng X,Wu L,Peng J,Yin F

更新日期：2014-01-16 00:00:00

abstract：:Axonal projections of ganglion cells to the superior colliculus (SC) and to the nucleus of the optic tract (NOT) were re-examined physiologically in the cat's retina. Taking care to minimize current spreads around the stimulating electrodes placed in the NOT or the SC, we reached a conclusion that a substantial propor...

journal_title：Brain research

authors： Sawai H,Fukuda Y,Wakakuwa K

更新日期：1985-08-19 00:00:00

abstract：:The characteristics of dopamine adenylate cyclase in the rat striatum were first studied on homogenates of fresh tissues. In the assay conditions used, dopamine (10(-4) M) stimulated the enzyme activity by 250%. This effect was completely blocked by fluphenazine (10(-5) M; Ki=9X10(-9) M) and by phentolamine (10(-5) M;...

journal_title：Brain research

authors： Bockaert J,Premont J,Glowinski J,Thierry AM,Tassin JP

更新日期：1976-05-07 00:00:00

abstract：:Cultured cells derived from Tay-Sachs disease (TSD) fetal cerebellum were shown to accumulate GM2 ganglioside when compared with control cultures. In contrast, fibroblasts derived from TSD fetal lung do not contain GM2. GM2 was identified by thin-layer chromatography (TLC) and confirmed by gas-liquid chromatography (G...

journal_title：Brain research

authors： Hoffman LM,Amsterdam D,Schneck L

更新日期：1976-07-23 00:00:00

abstract：:In the hippocampus, pyramidal cells (PCs) are not the only cell type sensitive to cholinergic stimulation. Two non-pyramidal cell types from animals as young as 8 days demonstrated clear, direct responses to application of cholinergic agonists. These cholinergic actions are excitatory, mostly blocked by muscarinic ant...

journal_title：Brain research

authors： Reece LJ,Schwartzkroin PA

更新日期：1991-12-06 00:00:00

abstract：:Focal electrical stimulation and glutamate microinjection in the nuclei reticularis gigantocellularis (NGC) and gigantocellularis pars alpha (NGC alpha) both inhibit the nociceptive tail-flick (TF) reflex in rats. The present experiments were undertaken to determine the transmitter(s) at the level of the lumbar spinal...

journal_title：Brain research

authors： Zhuo M,Gebhart GF

更新日期：1990-12-03 00:00:00