Quantitative analysis of glutamic acid decarboxylase-immunoreactive neurons in the anterior thalamus of the human brain.

Abstract:

:Local circuit neurons in the human anterior thalamus (AT) were identified on the basis of glutamic acid decarboxylase immunoreactivity (GAD-IR). GAD-IR neurons of the AT displayed small diameter somas with thin, sparsely-branching dendrites, consistent with the morphological characteristics of local circuit neurons found in the thalami of other mammals. Sampling techniques revealed an average of 42% of all neurons within the AT were GAD-IR, one of the highest reported percentages of local circuit neurons in the mammalian thalamus. The presence of high proportion of local circuit neurons in the AT may indicate the extent to which the Papez circuit has evolved within the human brain in comparison to other mammals.

journal_name

Brain Res

journal_title

Brain research

authors

Dixon G,Harper CG

doi

10.1016/s0006-8993(01)03194-8

subject

Has Abstract

pub_date

2001-12-27 00:00:00

pages

39-44

issue

1-2

eissn

0006-8993

issn

1872-6240

pii

S0006-8993(01)03194-8

journal_volume

923

pub_type

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