Abstract：
:Plasma concentrations of beta-endorphin were measured by radioimmunoassay in cats prepared chronically for sleep-waking polygraphic recordings and blood collection. beta-Endorphin (beta-END) levels were found to be stable in baseline conditions and were used as an index of stress. After habituation of each cat to experimental conditions in a veterinary pouch with head restraint, this partial restraint (45 min) or a short-lasting paralysis (30 min) induced by gallamine triethiodide did not significantly elevate plasma concentrations of beta-END. In contrast, hypoxia, ether-induced stress or tight immobilization of the limbs promoted a 7--8-fold increase in beta-END plasma levels. Sleep-waking patterns were not significantly different in restrained and paralyzed conditions. It is concluded that short-lasting paralysis induced in habituated animals by curarizing agents is not accompanied by a significant neuroendocrine response if all possible sources of pain are carefully avoided.
journal_name
Brain Resjournal_title
Brain researchauthors
Foutz AS,Dauthier C,Kerdelhué Bdoi
10.1016/0006-8993(83)91207-6subject
Has Abstractpub_date
1983-03-14 00:00:00pages
119-23issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(83)91207-6journal_volume
263pub_type
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