Abstract:
:Responses of antennal olfactory receptors of the Colorado potato beetle (Leptinotarsa decemlineata Say) to stimulation with 5 general green odour components, i.e. cis-3-hexen-1-ol, trans-2-hexenal, cis-3-hexenyl acetate, trans-2-hexen-1-ol and 1-hexanol, were recorded extracellularly. Response spectra derived from these recordings cannot be classified into distinct reaction types. The spectra overlap in their sensitivity to individual stimuli, but there are differences in their degree of specialization with a gradual conversion from generalist to specialist receptors. Moreover, specialization is found to different stimuli. Receptor reactions to stimulation with binary mixtures of 3 of these compounds indicated that suppression of the response to one chemical by another is very common in olfactory receptor cells. The more a receptor is specialized, the stronger is this suppression. Suppression in narrowly tuned olfactory receptor neurones, therefore, is expected to play a fundamental role in the recognition of natural odour blends.
journal_name
Brain Resjournal_title
Brain researchauthors
De Jong R,Visser JHdoi
10.1016/0006-8993(88)90961-4subject
Has Abstractpub_date
1988-04-26 00:00:00pages
18-24issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(88)90961-4journal_volume
447pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract::Mapping studies with central drug injections in the hungry rat have identified the perifornical lateral hypothalamus as being uniquely sensitive to the feeding suppressive effects of exogenous dopamine, as well as anorexic drugs which release endogenous catecholamines. In the present study, the hypothalamic dopamine-r...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(79)90899-0
更新日期:1979-08-17 00:00:00
abstract::The purpose of this study was to ascertain whether visual acuity or contrast sensitivity function (CSF) is proportional to visual cortical function based on fMRI volume and level of activation or Z-score. Forced choice procedures were utilized to measure the monocular log minimal angle of resolution (logMAR) visual ac...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2010.10.082
更新日期:2011-01-07 00:00:00
abstract::The carrier-mediated uptake of anionic and cationic amino acids by the basolateral face (blood side) of the isolated perfused sheep choroid plexus was demonstrated using the paired-tracer dilution technique. The uptake of these two classes of amino acid was higher than at the blood-brain barrier with no cross-competit...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(92)90731-n
更新日期:1992-05-29 00:00:00
abstract::Focal electrical stimulation and glutamate microinjection in the nuclei reticularis gigantocellularis (NGC) and gigantocellularis pars alpha (NGC alpha) both inhibit the nociceptive tail-flick (TF) reflex in rats. The present experiments were undertaken to determine the transmitter(s) at the level of the lumbar spinal...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(90)91825-2
更新日期:1990-12-03 00:00:00
abstract::In the brain, nitric oxide (NO) has been identified as a messenger molecule and a mediator of excitatory amino acid-induced neurotoxicity. In this study, the effects of NO on serum-induced mitogenesis and cell proliferation of the cerebellar glial cells were assessed. NO-generating agent, S-nitroso-N-acetylpenicillami...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(92)91678-8
更新日期:1992-10-02 00:00:00
abstract::Acute noradrenergic stimulation has previously been shown to stimulate brain (Na+, K+)-adenosine triphosphatase activity. Effects of repeated stimulation with piperoxane were examined in the present study. Daily piperoxane increased ouabain binding, measured 24 h after the last dose, after 4 days or 3 weeks treatment;...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(81)90258-4
更新日期:1981-06-01 00:00:00
abstract::The visual Wulst (VW) in the avian telencephalon is thought to be an avian equivalent of the mammalian striate cortex. Effects of electrical stimulation of VW were studied in the isthmo-optic nucleus (ION) of the Japanese quail by extracellular recording. Most ION neurons examined were activated by VW stimulation, and...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(87)90800-6
更新日期:1987-03-17 00:00:00
abstract::One hundred and four visual units of the (ventral) lateral geniculate nucleus (GL) of chicks (Gallus domesticus) were studied with extracellular microelectrodes. Most were extremely responsive to moving targets even at low speeds (0.1 degrees/sec). They were classified as follows. (1) movement-sensitive units with uni...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(79)90823-0
更新日期:1979-05-11 00:00:00
abstract::We have monitored the expression of c-fos protein in the medulla oblongata of the ferret, using immunocytochemistry, to identify the brainstem pathways involved in the mediation of nausea and vomiting caused by the antineoplastic drug cisplatin. Cisplatin administration resulted in c-fos-like immunoreactivity (FLI) in...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)91654-j
更新日期:1991-11-29 00:00:00
abstract::Thalamocortical connections were studied after injections of retrograde tracers were made into rostral or caudal parts of cortical area Fr2 in adult rats. The data reveal that both rostral Fr2 (rFr2) and caudal Fr2 (cFr2) receive input from the centrolateral, central medial, interanteromedial, mediodorsal, paracentral...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)91420-6
更新日期:1991-12-24 00:00:00
abstract::The effect of hypoxia on the structure and function of the synaptosomal membranes and myelin fraction (glial cells, neuronal cells bodies and axonal membranes) was investigated by measuring Na+,K(+)-ATPase activity and levels of lipid peroxidation products in cerebral cortical synaptosomal membranes and myelin fractio...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(93)91388-9
更新日期:1993-01-15 00:00:00
abstract::A central component of Attention Deficit Hyperactivity Disorder (ADHD) is increased distractibility in response to visual and auditory stimuli, which is linked to the superior colliculus (SC). Furthermore, there is now mounting evidence of altered collicular functioning in ADHD and it is proposed that a hyper-responsi...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2015.09.038
更新日期:2015-12-10 00:00:00
abstract::The hyperphagic properties of insulin (10 U/kg, s.c.) were transiently (2h) and dose-dependently inhibited (30%) by central pretreatment with naltrexone (20-50 micrograms, i.c.v.). The irreversible mu opioid antagonist, beta-funaltrexamine (B-FNA, 20 micrograms, i.c.v.) significantly inhibited insulin hyperphagia by 2...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)90977-4
更新日期:1991-05-03 00:00:00
abstract::Diverse neuropsychiatric diseases were recently linked to specific anti-neuronal autoantibodies targeting synaptic proteins. Symptoms can range from epileptic seizures to cognitive impairment to movement disorders, commonly responding to treatment with immunotherapy. Several of these autoantibodies target inhibitory s...
journal_title:Brain research
pub_type: 杂志文章,评审
doi:10.1016/j.brainres.2018.09.009
更新日期:2018-12-15 00:00:00
abstract::By utilizing the microinjection of low nanoliter volumes of convulsant drug and recording from the injection site, we have been able to electrophysiologically identify a layer of cat striate cortex that is most sensitive to the epileptogenic effects of penicillin. This band encompasses cortical depths of approximately...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(82)91084-8
更新日期:1982-06-10 00:00:00
abstract::Human arachnoid villi were studied ultrastructurally to clarify the mechanism of cerebrospinal fluid absorption. Arachnoid villi of humans showed quite different features from those of animals. The former were not always invested with endothelial linings as previously reported in the latter. Instead, there was a cover...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(86)91220-5
更新日期:1986-10-01 00:00:00
abstract::Previous results indicate that the dopaminergic system in the anterior medial zona incerta (ZI) exerts a stimulatory effect on LH release. In this report changes in dopamine (DA) turnover in the ZI, preoptic area (POA) and arcuate/median eminence area (ARC/ME) (as assessed by the rate of decline in DA concentration af...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(88)90915-8
更新日期:1988-03-15 00:00:00
abstract::The olfactory sensory neurons are unique in the vertebrate nervous system in that they are replaced following experimentally induced degeneration. Unilateral removal of the olfactory bulb in hamster results in degeneration of all mature receptor neurons followed by a neurogenesis and partial replacement of the recepto...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(84)90483-9
更新日期:1984-07-30 00:00:00
abstract::Although transsynaptic tracing with peripheral injection of pseudorabies virus (PRV) has been extensively characterized, several methodological issues related to central application of this tracer have not been addressed. In the present study, we addressed the following three issues by using microinjection of a cockta...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(99)01680-7
更新日期:1999-08-14 00:00:00
abstract::We studied the propagation of spike discharges and the changes in local cerebral blood flow (LCBF) by means of the electroencephalogram (EEG) and autoradiographs to elucidate the underlying mechanism and the propagation pathway in rats with limbic seizures. Seizures were induced by the unilateral microinjection of kai...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)91923-2
更新日期:1994-01-21 00:00:00
abstract::Previous research has shown that, in freely moving laboratory rats, the odors of benzyl alcohol, camphor, carvacrol, isopentenyl methyl sulfide, 2-propylthietane, salicylaldehyde, trimethylthiazoline, and xylene (plus other compounds) elicit high amplitude bursts of roughly 20-Hz waves (beta-waves) in the olfactory bu...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(01)03225-5
更新日期:2002-01-11 00:00:00
abstract::The present investigation is aimed at studying the influence of the striate cortex (area 17 or V1) upon responses of area 18a. Electrical activity was recorded from neurons in area 18a through glass micropipettes. At the same time lidocaine hydrochloride was injected in the same retinotopic register of area 17. Forty ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(90)91371-m
更新日期:1990-03-05 00:00:00
abstract::The retinohypothalamic tract (RHT) is a direct pathway from the retina to the suprachiasmatic nucleus (SCN). Electrical stimulation of the optic nerve or optic chiasm activates the RHT and produces shifts in phase of a circadian rhythm in SCN neuron activity in rat hypothalamic slices in vitro. The phase response curv...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(93)91118-c
更新日期:1993-06-25 00:00:00
abstract::Traumatic brain injury (TBI) contributes to morbidity in children, and more boys experience TBI. Cerebral autoregulation is impaired after TBI, contributing to poor outcome. Cerebral Perfusion Pressure (CPP) is often normalized by use of vasoactive agents to increase mean arterial pressure (MAP). In prior studies of n...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2017.06.010
更新日期:2017-09-01 00:00:00
abstract::Odorant-stimulated formation of cAMP in olfactory receptor neurons may mediate olfactory signal transduction. The response is short and desensitization occurs rapidly, possibly by induction of cyclic nucleotide phosphodiesterase (PDE) activity. Previously, we showed that two low Km PDEs regulate hydrolysis of cAMP in ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(93)91401-d
更新日期:1993-05-07 00:00:00
abstract::In this study, the effects of chronic morphine administration (20-30 days) on long-term potentiation (LTP) were investigated at the Schaffer collateral-CA1 pyramidal cell synapses of the rat hippocampal slices. Orthodromic population spike (OPS) amplitude and delay (peak latency) were measured as indices of increase i...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(98)01148-2
更新日期:1999-01-09 00:00:00
abstract::We have already demonstrated that, although exogenous gamma-aminobutyric acidA (GABAA) receptor agonist is capable of inhibiting the activity of luteinizing hormone releasing hormone (LHRH) pulse generator, the reduction in the endogenous GABAA receptor activity does not have a significant effect in ovariectomized rat...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)90145-7
更新日期:1994-04-04 00:00:00
abstract::Wheat germ agglutinin conjugated to horseradish peroxidase (WGA-HRP) was used to study transneuronal transport in the developing rat visual pathways. Intraocular injections of WGA-HRP were made in neonatal albino rat pups at different ages from the day of birth, postnatal day 0 (P0), to one month of age. Transneuronal...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0165-3806(88)90087-9
更新日期:1988-01-01 00:00:00
abstract::Dual-labeling immunohistochemical or in situ hybridization studies for the recently cloned epsilon-subunit and several neuropeptides were performed in the rat hypothalamus. We revealed an extensive co-expression (>90%) with hypocretin (Hcrt), oxytocin (OT), the gonadotropin-releasing hormone (GnRH), and the melanin-co...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(02)04270-1
更新日期:2003-03-28 00:00:00
abstract::Hypothalamic control of thermoregulatory evaporation has been examined in hydrated and dehydrated cats exposed to warm ambient temperatures. Reduction in evaporative cooling during dehydration is associated with increased hypothalamic temperature. Local thermal stimulation of the hypothalamus indicates that the thermo...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(81)90120-7
更新日期:1981-02-09 00:00:00