Activation of the isthmo-optic neurons by the visual Wulst stimulation.

abstract：:Dapsone (4,4'-diaminodiphenylsulfone) is employed in the chemotherapy against leprosy. Dapsone also prevents neuronal damage induced by glutamate agonists. As glutamate excitotoxicity is implicated in the damage after ischemia, we tested the ability of dapsone to prevent ischemic injury in a model of permanent middle ...

journal_title：Brain research

authors： Ríos C,Nader-Kawachi J,Rodriguez-Payán AJ,Nava-Ruiz C

更新日期：2004-03-05 00:00:00

abstract：:Previous studies have clearly shown that the progressive decrease of growth hormone (GH) secretion occurring during ageing is coupled with a reduced responsiveness of pituitary GHRH receptors both in terms of GH secretion and activation of the adenylyl cyclase (AC), in the presence of increased basal values of the enz...

journal_title：Brain research

authors： Qing Y,Parenti M,Guzzi F,Ceresoli G,Müller EE,Cocchi D

更新日期：1994-04-25 00:00:00

abstract：:The levels of PLCgamma, a phospholipase C (PLC) isozyme, were higher in the cytosol fraction than in the membrane fraction in several control brain regions. The levels of PLCgamma were significantly elevated in the membrane, but not in the cytosolic fraction of the hippocampus of AD subjects. In the superior and middl...

journal_title：Brain research

authors： Zhang D,Dhillon H,Prasad MR,Markesbery WR

更新日期：1998-11-16 00:00:00

abstract：:To study morphological changes in the cortex that follow repeated ischemia, one, two, and three 7-min unilateral occlusions of the carotid artery at 6-h intervals, and three, four, and five 7-min similar occlusions at 12-h intervals were produced in gerbils. Animals with one and two 7-min occlusions at 6-h intervals s...

journal_title：Brain research

authors： Hanyu S,Ito U,Hakamata Y,Yoshida M

更新日期：1995-07-17 00:00:00

abstract：:The aim of this work was to study the role of the dorsal noradrenergic ascending pathway (DNAP), which originates in the locus coeruleus (LC) on the preovulatory surge of luteinizing hormone (LH) follicle-stimulating hormone (FSH) and prolactin (PRL) by producing bilateral electrolytic lesions (cathodal or anodal) in ...

journal_title：Brain research

authors： Anselmo-Franci JA,Franci CR,Krulich L,Antunes-Rodrigues J,McCann SM

更新日期：1997-09-05 00:00:00

abstract：:Synaptosomes assemble an equatorial coil of microtubules during incubation at 37 degrees C. Stimulation of synaptosomes by veratridine or A23187 for 5 min results in disassembly of the microtubules. The role of microtubule disassembly in neurotransmitter release was investigated using the microtubule-stabilizing drug ...

journal_title：Brain research

authors： Burgoyne RD,Cumming R

更新日期：1983-11-28 00:00:00

abstract：:Studies related to brain oscillations pervade the neuroscience literature. Functional correlates of oscillations in the delta, theta, alpha, beta and gamma frequency windows are interpreted in several ways. However, only a small number of reports indicate the need for overall interpretations by integrating all type of...

journal_title：Brain research

authors： Başar E

更新日期：2008-10-15 00:00:00

abstract：:Transcription factors of the nuclear factor-kappa B (NF-kappaB) p65/RelA may be involved in neuronal cell death. We examined the involvement of NF-kappaB p65 in N-methyl-D-aspartate (NMDA)-induced upregulation of interleukin (IL)-1beta, a proinflammatory cytokine, and subsequent neurotoxicity in the rat retina. Immuno...

journal_title：Brain research

authors： Kitaoka Y,Munemasa Y,Nakazawa T,Ueno S

更新日期：2007-04-20 00:00:00

abstract：:Murine spinal cord primary mixed cultures were treated with the respiratory inhibitor, rotenone, to mimic hypoxic conditions. Under these conditions neurons rapidly underwent oncosis (necrosis) with a complete loss in viability occurring within 260 min; however, astrocytes, which accounted for most of the cell populat...

journal_title：Brain research

authors： Litsky ML,Hohl CM,Lucas JH,Jurkowitz MS

更新日期：1999-03-13 00:00:00

abstract：:Dexmedetomidine (Dex) has the neuroprotective effect on cerebral ischemia-reperfusion injury (CIRI). But the mechanism is not yet clear. In this study, we established a model of middle cerebral artery occlusion (MCAO) and treated primary cortical neurons with oxygen glucose deprivation (OGD), followed by Dex treatment...

journal_title：Brain research

authors： Liu C,Fu Q,Mu R,Wang F,Zhou C,Zhang L,Yu B,Zhang Y,Fang T,Tian F

更新日期：2018-12-15 00:00:00

abstract：:125I-alpha-Scorpion toxin (alpha-ScTx) binds to a component of the voltage-sensitive Na+ channel. We have previously shown that receptor capacity on dissociated mouse brain cells increases between days 12 and 19 of fetal life as does the expression of neurotoxin-sensitive 22Na+ influx. In the present study we have inv...

journal_title：Brain research

authors： Martin-Moutot N,Cau P,Berwald-Netter Y,Couraud F

更新日期：1987-03-01 00:00:00

abstract：:In anesthetized, artificially ventilated cats, pretreated with the muscarinic antagonist scopolamine, the effect of naloxone on the efficacy of nicotinic transmission in the superior cervical ganglion was used as a test of endogenous opioid release by the preganglionic axons. The cervical sympathetic trunk (CST) was s...

journal_title：Brain research

authors： Zhang C,Bachoo M,Polosa C

更新日期：1991-05-10 00:00:00

abstract：:[d-Ala(2)-d-Leu(5)]-Enkephalin (DADLE) has shown promising results in protecting neurons from damages. However, the mechanism for this protection is still under investigation. The current study was carried out to test the hypothesis that DADLE may regulate cellular transcription in neurons. SH-SY5Y cells and primary c...

journal_title：Brain research

authors： Tian J,Gu Y,Sun K,Wang B,Chen J,Wang X,Su D

更新日期：2014-05-27 00:00:00

abstract：:The cholinergic neurotoxin, AF64A-picrylsulfonate, was unilaterally infused into the dorsal hippocampus of Wistar rats (2 nmol/2 microliters/4 min; A 6.2, Ls 1.5, H 6.5, Paxinos and Watson). After 19 days the for immunohistochemical staining of choline acetyltransferase (ChAT). Morphometry and counting of ChAT-immunor...

journal_title：Brain research

authors： Tonnaer JA,Lammers AJ,Wieringa JH,Steinbusch HW

更新日期：1986-04-02 00:00:00

abstract：:Systemic administration of mesenchymal stem cells (MSCs) following cerebral infarction exerts functional improvements. Previous research has suggested potential therapeutic mechanisms that promote neuroprotection and synaptogenesis. These include secretion of neurotrophic factors, remodeling of neural circuits, restor...

journal_title：Brain research

authors： Nagahama H,Nakazaki M,Sasaki M,Kataoka-Sasaki Y,Namioka T,Namioka A,Oka S,Onodera R,Suzuki J,Sasaki Y,Kocsis JD,Honmou O

更新日期：2018-09-15 00:00:00

abstract：:These experiments examined the effects, on retention, of posttraining intra-amygdala administration of norepinephrine (NE), and propranolol. Rats were trained on a one-trial step-through inhibitory avoidance task and tested for retention 24 h later. Injections were administered bilaterally (1.0 microliter/injection) t...

journal_title：Brain research

authors： Liang KC,Juler RG,McGaugh JL

更新日期：1986-03-12 00:00:00

abstract：:Whereas the role of the hippocampus for spatial learning and long-term memory is largely undisputed, there is less evidence for a participation of hippocampal structures in spatial working memory operations. In an fMRI study (functional magnetic resonance imaging), we therefore examined the role of the hippocampus dur...

journal_title：Brain research

authors： Toepper M,Markowitsch HJ,Gebhardt H,Beblo T,Thomas C,Gallhofer B,Driessen M,Sammer G

更新日期：2010-10-01 00:00:00

abstract：:Following lesions of the pyramidal tract in hamsters, retrograde changes were studied in the sensorimotor cortex and in the pyramidal tract axons proximal to the lesion, at survival times ranging from 2 weeks to 14 months. Severe cell shrinkage occurred in layer 5 pyramidal neurons as early as 2 weeks, but there was n...

journal_title：Brain research

authors： Kalil K,Schneider GE

更新日期：1975-05-16 00:00:00

abstract：:We have examined the saturation features (Kd and Bmax) of [3H]naloxone binding in rat brain regions in cytoarchitectonically intact tissues of naive, morphine dependent and precipitated withdrawal states using quantitative film autoradiography. Sixty-one saturation experiments in 13 regions of naive rat brains yielded...

journal_title：Brain research

authors： Geary WA 2nd,Wooten GF

更新日期：1985-12-23 00:00:00

abstract：:The early electrophysiological phenomena linked to systemic inflammation are largely underexplored. We developed here local field analyses to detect prodromal oscillatory abnormalities. We identified early band-specific patterns in local field potential recorded from freely-moving rats injected intraperitoneally with ...

journal_title：Brain research

authors： Mamad O,Islam MN,Cunningham C,Tsanov M

更新日期：2018-02-15 00:00:00

abstract：:We examined the effects of nicotinic drugs on the metabolites of [3H]dopamine (DA) released from rat striatal synaptosomes in comparison with the effects of high K+ and methamphetamine stimulation. The pattern of outflow of [3H]DA and its metabolites induced by nicotine stimulants, acetylcholine (ACh), nicotine and lo...

journal_title：Brain research

authors： Takano Y,Sakurai Y,Kohjimoto Y,Honda K,Kamiya HO

更新日期：1983-11-21 00:00:00

abstract：:Synaptosomes prepared from fresh human cerebral cortex were shown to be morphologically similar to those from other species. On incubation, they took up oxygen at a high and linear rate and accumulated potassium against a concentration gradient. In response to depolarization by raised extracellular K+ or addition of v...

journal_title：Brain research

authors： Dodd P,Hardy JA,Oakley AE,Strong AJ

更新日期：1981-11-16 00:00:00

abstract：:Extracellular recordings from 141 rat supraoptic nucleus neurons maintained in vitro in a perfused hypothalamic explant indicated that the excitability of 85% of cells was enhanced by the addition of 10-200 microM norepinephrine (NE) and the alpha-agonist methoxamine (MOXY), but not by isoproterenol, to the perfusion ...

journal_title：Brain research

authors： Randle JC,Bourque CW,Renaud LP

更新日期：1984-07-30 00:00:00

abstract：:To examine the structural interactions between synaptically connected neurons in Aplysia, we have developed a method for simultaneously labeling two identified cell with different and compatible intraneuronal marking agents (horseradish peroxidase and [3H]N-acetyl-D-galactosamine) visible in both the light and electro...

journal_title：Brain research

authors： Thompson EB,Bailey CH

更新日期：1979-09-14 00:00:00

abstract：:Although chronic neuropathic pain disorders are more prevalent in the senescent population, little is known about how the aging process alters the thermal hyperalgesic sensitivity to peripheral nerve injury. In this study, neuropathic pain was induced in young, mature and aged FBNF1 hybrid rats via unilateral ligation...

journal_title：Brain research

authors： Novak JC,Lovell JA,Stuesse SL,Cruce WL,McBurney DL,Crisp T

更新日期：1999-07-03 00:00:00

abstract：:Quantitative [125I]protein G-based immunohistochemistry was used to map the distribution of beta1 thyroid hormone receptor (TRbeta1) in normal and thyroidectomized adult rat brain, using a previously characterized polyclonal antibody. The distribution of TRbeta1-like immunoreactivity in normal brain was largely but no...

journal_title：Brain research

authors： Nobrega JN,Raymond R,Puymirat J,Belej T,Joffe RT

更新日期：1997-06-27 00:00:00

abstract：:Dysregulation of the brain emotional systems that mediate arousal and stress is a key component of the pathophysiology of drug addiction. Drug addiction is a chronically relapsing disorder characterized by a compulsion to seek and take drugs and the development of dependence and manifestation of a negative emotional s...

journal_title：Brain research

authors： Koob GF

更新日期：2009-10-13 00:00:00

abstract：:Deltamethrin is a highly potent pyrethroid insecticide that causes hypersensitivity, choreoathetosis, tremors, and paralysis in mammals. It is known to modify the sodium channel in such a way as to prolong the tail current associated with step repolarization following a depolarizing pulse. Using the axial-wire voltage...

journal_title：Brain research

authors： Brown LD,Narahashi T

更新日期：1992-07-03 00:00:00

abstract：:The relationship between placental antigen X-P2 (PAX)-immunoreactive glomeruli and intensely acetylcholinesterase-reactive (IAE) patchy regions was evaluated by comparison of neighboring cryostat sections of the rat olfactory bulb. Both groups of distribution show similar necklace patterns. Each IAE region consists of...

journal_title：Brain research

authors： Shinoda K,Ohtsuki T,Nagano M,Okumura T

更新日期：1993-07-30 00:00:00

abstract：:The neocortex has proven resistant to LTP induction using standard in vitro and acute, in vivo preparations. Because the neocortex is widely thought to be involved in long-term information storage, this resistance raises questions about the validity of LTP as a memory model. Recently, we have shown that the neocortex ...

journal_title：Brain research

authors： Boyd TE,Trepel C,Racine RJ

更新日期：2000-10-20 00:00:00