The laminar sensitivity of cat striate cortex to penicillin induced epileptogenesis.

abstract：:The conduction velocity of frog ischiadic nerves incubated in vitro in osmolarities between 220 and 1000 mOsm decreased with the degree of fiber shrinkage. The latter (non-circularity factor) was determined from computer-assisted measurements in freeze-substituted or in chemically fixed fibers. Freeze-substituted norm...

journal_title：Brain research

authors： Minwegen P,Friede RL

更新日期：1984-04-09 00:00:00

abstract：:Although cocaine shares the ability of fenfluramine to inhibit the synaptic reuptake of serotonin, previous observations from our group suggest that the genomic effects of fenfluramine in the rat striatum are primarily mediated by dopaminergic rather than serotonergic mechanisms. To compare and further understand the ...

journal_title：Brain research

authors： Torres G,Rivier C

更新日期：1994-05-30 00:00:00

abstract：:The effect of a single train of electrical hippocampal stimulation on ACTH and corticosterone (CS) responses to subsequent photic stimulation was studied in freely moving male rats. The hippocampal stimulation inhibited the stress-induced rise [corrected] in serum CS levels up to 150 h when compared to sham stimulated...

journal_title：Brain research

authors： Feldman S,Weidenfeld J

更新日期：2001-08-17 00:00:00

abstract：:These experiments examine the dependence of medial hypothalamic alpha 2-receptor binding on the availability of circulating glucose. Food deprivation and tolbutamide-induced hypoglycemia both diminished alpha 2-binding. These binding results were highly correlated with serum glucose levels. Prevention of tolbutamide h...

journal_title：Brain research

authors： Chafetz MD,Parko K,Diaz S,Leibowitz SF

更新日期：1986-10-08 00:00:00

abstract：:A novel gold phosphate complex called Black-Gold II with improved myelin staining properties has been developed. It differs from its predecessor, Black-Gold, in that it is highly water soluble at room temperature. This unique physical property confers a number of advantages for the high resolution staining of myelinat...

journal_title：Brain research

authors： Schmued L,Bowyer J,Cozart M,Heard D,Binienda Z,Paule M

更新日期：2008-09-10 00:00:00

abstract：:Calretinin has been identified as a brain specific calcium-binding protein which appears as a prominent protein in the cochlear nucleus. We identified and localized calretinin in the guinea pig and rat inner ear using polyclonal antibodies. Immunoblot analyses of guinea pig and rat auditory nerve homogenates revealed ...

journal_title：Brain research

authors： Dechesne CJ,Winsky L,Kim HN,Goping G,Vu TD,Wenthold RJ,Jacobowitz DM

更新日期：1991-09-27 00:00:00

abstract：:Endogenous opioids play a role in the regulation of LH-RH neurosecretion throughout the estrous cycle and during the preovulatory LH surge on proestrus. Experimental evidence suggests that opioid influence may be altered with age, and it has been hypothesized that these alterations may contribute to the loss of regula...

journal_title：Brain research

authors： Rubin BS

更新日期：1993-01-22 00:00:00

abstract：:Responses of antennal olfactory receptors of the Colorado potato beetle (Leptinotarsa decemlineata Say) to stimulation with 5 general green odour components, i.e. cis-3-hexen-1-ol, trans-2-hexenal, cis-3-hexenyl acetate, trans-2-hexen-1-ol and 1-hexanol, were recorded extracellularly. Response spectra derived from the...

journal_title：Brain research

authors： De Jong R,Visser JH

更新日期：1988-04-26 00:00:00

abstract：:The effects of clonidine (CLO) and phentolamine (PHE) on the sleep-waking cycle in the cat treated with alpha-methyl-p-tyrosine (AMPT) were investigated with continuous 16--24 h polygraphic recordings. For the evaluation of possible cholinergic interactions in the paradoxical sleep (PS) increasing effect of AMPT, an a...

journal_title：Brain research

authors： Leppävuori A

更新日期：1980-07-07 00:00:00

abstract：:In this study, we investigated the modulatory effect of 5alpha-pregnan-3alpha-ol-20-one, a neurosteroid, on the binding characteristics of [3H]flunitrazepam (2 nM), [3H]muscimol (5 nM), and 4 nM [35S]t-butylbicyclophosphorothionate (TBPS) in cerebral cortex, cerebellum, and hippocampus of control, ethanol-dependent, a...

journal_title：Brain research

authors： Mehta AK,Ticku MK

更新日期：1998-09-14 00:00:00

abstract：:The lateral geniculate nucleus (LGN) receives input from the retina that is spatially organized into a receptive-field center and surround. It maintains this organization in the signal that it sends to the visual cortex. Previous studies have focused on changes in the receptive-field 'surround' that are generated at t...

journal_title：Brain research

authors： Norton TT,Holdefer RN,Godwin DW

更新日期：1989-05-29 00:00:00

abstract：:The development of hypertension in spontaneously hypertensive rats (SHR) and hyperactive voiding in rats with urethral obstruction are characterized by abnormal smooth muscle growth, increased tissue levels of nerve growth factor (NGF) and altered patterns of innervation. The present study was undertaken to determine ...

journal_title：Brain research

authors： Spitsbergen JM,Clemow DB,McCarty R,Steers WD,Tuttle JB

更新日期：1998-04-20 00:00:00

abstract：:The cat substantia nigra (SN) pars reticulata (SNR) has been observed electron microscopically after ibotenic acid injections into the caudate nucleus (Cd) and horseradish peroxidase injections into the nucleus tegmenti pedunculopontinus pars compacta (TPC). As a result, degenerating striatal terminals were found to m...

journal_title：Brain research

authors： Tokuno H,Moriizumi T,Kudo M,Kitao Y,Nakamura Y

更新日期：1989-04-17 00:00:00

abstract：:Mechanisms of neuronal death following neuronal damage due to domoic acid are not completely defined. Bcl-2, a survival protein, protects neurons from ischemia and excitotoxin-induced damage. We previously demonstrated that Bcl-2 shuttles calcineurin to its substrates and may regulate calcium release from internal sto...

journal_title：Brain research

authors： Erin N,Billingsley ML

更新日期：2004-07-16 00:00:00

abstract：:In the neocortex, fast excitatory synaptic transmission can typically be blocked by using excitatory amino acid (EAA) receptor antagonists. In recordings from layer II/III neocortical pyramidal neurons, we observed an evoked excitatory postsynaptic potential (EPSP) or current (EPSC) in the presence of EAA receptor ant...

journal_title：Brain research

authors： Chu ZG,Zhou FM,Hablitz JJ

更新日期：2000-12-29 00:00:00

abstract：:In the present study, we investigated the co-localization pattern of the delta subunit with other subunits of GABA(A) receptors in the rat brain using immunoprecipitation and Western blotting techniques. Furthermore, we investigated whether low concentrations of ethanol affect the delta-subunit-containing GABA(A) rece...

journal_title：Brain research

authors： Mehta AK,Marutha Ravindran CR,Ticku MK

更新日期：2007-08-24 00:00:00

abstract：:Activation of a purinergic P2 receptor by adenosine 5'-triphosphate (ATP) has previously been shown to open a non-selective cation channel with a reversal potential of approximately 0 mV. We examined the effect of P2 receptor activation on voltage-gated ionic currents in acutely isolated CA3 pyramidal neurons from gui...

journal_title：Brain research

authors： Dave S,Mogul DJ

更新日期：1996-04-09 00:00:00

abstract：:Homogenates of rat ventral and dorsal spinal cords were subjected to differential and gradient centrifugation on linear sucrose gradients following lysis of a synaptosomal fraction. The distribution of calcitonin gene-related peptide (CGRP) and substance P (SP) in dorsal spinal cord as well as the distribution of sero...

journal_title：Brain research

authors： Fried G,Franck J,Brodin E,Born W,Fischer JA,Hiort W,Hökfelt T

更新日期：1989-10-16 00:00:00

abstract：:The dorsal lateral geniculate nucleus of tree shrews is very susceptible to the neurotoxic effects of kainic acid. In addition to neuronal loss, there is a profound loss of retinal terminals that is manifested through a disruption of anterograde transport of WGA/HRP from the retina to the kainic acid-lesioned area of ...

journal_title：Brain research

authors： Horn KM,Carey RG

更新日期：1987-07-21 00:00:00

abstract：:For the evaluation of glutamatergic and GABAergic transmission during seizures, rat hippocampal CA1 and CA3 areas were separately assessed by brain microdialysis, and extracelluar glutamate and GABA were measured through the course of the seizures after a systemic administration of kainic acid (KA). The generalized co...

journal_title：Brain research

authors： Ding R,Asada H,Obata K

更新日期：1998-07-27 00:00:00

abstract：:Using an isolated neonatal rat spinal cord preparation, we have studied the ability of hydrogen peroxide to act as a source of oxygen for mammalian central nervous system (CNS) maintained in vitro. We report here that hydrogen peroxide, in low concentrations (0.001-0.004%), can effectively provide the only source, or ...

journal_title：Brain research

authors： Walton K,Fulton B

更新日期：1983-11-14 00:00:00

abstract：:To investigate the reversibility of neuronal functions during deep and mild hypothermia, we have examined changes in membrane properties of pyramidal neurons of the CA3 region of hippocampal slices during cooling and rewarming (8 approximately 37 degrees C) of the perfusion medium. Hypothermia reduced the excitatory p...

journal_title：Brain research

authors： Aihara H,Okada Y,Tamaki N

更新日期：2001-03-02 00:00:00

abstract：:The Thy-1 antigen is a cell surface glycoprotein found in neural tissue of all mammalian species so far studied. The distribution and amount of this antigen has been measured on 4 human neuronal and 2 neuroglial cell lines and on fresh tumour cells of neuronal origin. In 3 out of 4 neuronal lines (LAN-1, TR14, CHP 212...

journal_title：Brain research

authors： Kemshead JT,Ritter MA,Cotmore SF,Greaves MF

更新日期：1982-03-25 00:00:00

abstract：:Nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d) activity and the central terminal fields of branches of the mandibular and chorda tympani nerves were visualized histochemically at the same time using transganglionic transport of wheat germ agglutinin conjugated with horseradish peroxidase. The blue NA...

journal_title：Brain research

authors： Takemura M,Tsujio A,Iwase K,Shimada T,Shigenaga Y

更新日期：1998-01-19 00:00:00

abstract：:The quantitative 2-[14C]deoxyglucose autoradiographic method was used to study the effects of the acute administration of a sedative anticonvulsant dose of diazepam (2 mg/kg) on rat brain energy metabolism. This benzodiazepine was injected to rats chronically treated for two weeks either by caffeine (10 mg/kg/day) or ...

journal_title：Brain research

authors： Nehlig A,Daval JL,Pereira de Vasconcelos A,Boyet S

更新日期：1987-09-01 00:00:00

abstract：:Alpha-lipoic acid (ALA) is an endogenous short-chain fatty acid that has beneficial protective effects against various vascular diseases. In this study, we sought to determine whether ALA could induce pre- or post-treatment protective effects against simulated ischemia and reperfusion-induced cerebral endothelial cell...

journal_title：Brain research

authors： Xie R,Li X,Ling Y,Shen C,Wu X,Xu W,Gao X

更新日期：2012-10-30 00:00:00

abstract：:We used double staining immunocytochemical techniques to determine whether nitric oxide (NO) and Fos immunoreactivity induced by noxious visceral stimulation were colocalized in the neurons of the supraspinal areas. We observed a considerable increase in Fos-positive neurons in many brain areas after noxious stimulati...

journal_title：Brain research

authors： Rodella L,Rezzani R,Agostini C,Bianchi R

更新日期：1999-07-10 00:00:00

abstract：:Dravet syndrome (DS) is a genetic form of severe epilepsy often associated with mutation of the SCN1A gene encoding the voltage gated sodium channel Nav1.1. Typically refractive to conventional therapy, serotonin neurotransmission may be an innovative target for treatment. To further understand the role of serotonin i...

journal_title：Brain research

authors： Hatini PG,Commons KG

更新日期：2019-12-01 00:00:00

abstract：:Locally applied ciliary neurotrophic factor (CNTF) has a powerful effect on retrograde axonal reaction following facial nerve crush in neonatal rats. We examined whether it also exerts a strong effect on retrograde axonal reaction in young adult rats when administered subcutaneously. The dose was 1 mg/kg body weight, ...

journal_title：Brain research

authors： Ulenkate HJ,Gispen WH,Jennekens FG

更新日期：1996-04-22 00:00:00

abstract：:The genomic response following brain ischemia is very complex and involves activation of both protective and detrimental signaling pathways. Immediate early genes (IEGs) represent the first wave of gene expression following ischemia and are induced in extensive regions of the ischemic brain including cerebral cortex a...

journal_title：Brain research

authors： Rickhag M,Teilum M,Wieloch T

更新日期：2007-06-02 00:00:00