Monosynaptic striatal inputs to the nigrotegmental neurons: an electron microscopic study in the cat.

abstract：:Adult male guinea pigs were castrated and 24 h later injected with [3H]dihydrotestosterone. Their pituitary glands were then processed for autoradiographic and immunocytochemical analyses. Three percent of the parenchymal cells in the pars distalis were radiolabelled. These cells were primarily gonadotrophs; a small p...

journal_title：Brain research

authors： Herbert DC,Sheridan PJ

更新日期：1986-01-08 00:00:00

abstract：:Microtubule-associated protein 1B (MAP1B) is expressed at high levels during development of the nervous system and is localized primarily in neurons while specific phosphorylated isoforms of MAP1B are localized exclusively in growing axons. The levels of MAP1B are down regulated in most regions of the adult CNS, but r...

journal_title：Brain research

authors： Ma D,Chow S,Obrocka M,Connors T,Fischer I

更新日期：1999-03-27 00:00:00

abstract：:The active and passive properties of petrosal ganglion sensory neurons with axons in the glossopharyngeal nerve were examined with intracellular microelectrodes in an in vitro preparation. Glossopharyngeal neurons could be classified into two groups: H-cells showing an inflexion or hump on the falling phase of the spi...

journal_title：Brain research

authors： Morales A,Ivorra I,Gallego R

更新日期：1987-01-20 00:00:00

abstract：:FRAT1 was originally characterized as a protein frequently rearranged in advanced T cell lymphoma, which inhibits GSK-3-mediated phosphorylation of beta-catenin and positively regulates the Wnt signaling pathway. FRAT1 has been identified as a proto-oncogene involved in tumorigenesis. Previous studies have shown that ...

journal_title：Brain research

authors： Guo G,Mao X,Wang P,Liu B,Zhang X,Jiang X,Zhong C,Huo J,Jin J,Zhuo Y

更新日期：2010-03-12 00:00:00

abstract：:Horseradish peroxidase application in exsanguinated, pre-perfused newts, Pleurodeles waltlii, appeared to be very useful to study the connections of the area octavolateralis. Efferents from the octavolateral area course via bilateral lemnisci to the tectum and a presumptive torus semicircularis in the midbrain. Additi...

journal_title：Brain research

authors： Gonzalez A,Munoz M

更新日期：1987-10-13 00:00:00

abstract：:This study used microdialysis to monitor extracellular levels of 5-HT and its metabolite, 5-hydroxyindole acetic acid (5-HIAA) in the lateral hypothalamus (LH) and hippocampus of freely moving rats that had developed a CTA to a 2.5 mM saccharin solution (CS) following its pairing with illness induced by lithium chlori...

journal_title：Brain research

authors： West HL,Mark GP,Hoebel BG

更新日期：1991-08-09 00:00:00

abstract：:[3H]Paroxetine binding to human brain tissue was characterized. Competition studies in the putamen and frontal cortex revealed single-site binding models for binding sensitive to 5-hydroxytryptamine (5-HT) (Ki 1-3 microM) and citalopram (Ki 0.6 nM), which displaced the same amount of binding. However, desipramine, nor...

journal_title：Brain research

authors： Bäckström I,Bergström M,Marcusson J

更新日期：1989-05-08 00:00:00

abstract：:From 4 or 5 postnatal days, rat pups were either reared by their mothers (MR) or artificially reared (AR) without their mothers by infusion of 'milk' through a gastric cannula. In AR, but not MR, pups the left eye was more likely to open first than the right eye (P less than 0.001). The left-biassed eye-opening of AR ...

journal_title：Brain research

authors： Smart JL,Tonkiss J,Massey RF

更新日期：1986-07-01 00:00:00

abstract：:Gaze processing was investigated using event-related potentials in two different tasks in which front-view and 3/4-view faces were presented, with eyes gazing straight ahead or averted. Task alternated between an explicit gaze direction judgment and a judgment on head orientation where gaze was irrelevant. Accuracy an...

journal_title：Brain research

authors： Itier RJ,Alain C,Kovacevic N,McIntosh AR

更新日期：2007-10-26 00:00:00

abstract：:We examined regional cerebral metabolic rates for glucose (rCMRglc) and brain incorporation coefficients (k*) of each of three intravenously infused fatty acid radiotracers, [9,10-(3H)]palmitate ([3H]PAM), [1-(14C)]arachidonate ([14C]AA) and [1-(14C)]docosahe-xaenoate ([14C]DHA), in awake rats fully kindled by once-da...

journal_title：Brain research

authors： Arai T,Jones CR,Rapoport SI,Weiss SR

更新日期：1996-12-16 00:00:00

abstract：:Ischemic insults affecting the internal capsule result in sensory-motor disabilities which adversely affect the patient's life. Cerebral endothelial cells have been reported to exert a protective effect against brain damage, so the transplantation of healthy endothelial cells might have a beneficial effect on the outc...

journal_title：Brain research

authors： Puentes S,Kurachi M,Shibasaki K,Naruse M,Yoshimoto Y,Mikuni M,Imai H,Ishizaki Y

更新日期：2012-08-21 00:00:00

abstract：:Ion-sensitive microelectrodes were used to study the behavior of extracellular ions in rat sciatic nerve during and following activity. Nerve stimulation produced increases in [K+]o that were dependent upon the frequency and duration of stimulation; no change in extracellular pH occurred with stimulation. Increases in...

journal_title：Brain research

authors： Hoppe D,Chvatal A,Kettenmann H,Orkand RK,Ransom BR

更新日期：1991-06-21 00:00:00

abstract：:Sensory fibers trapped in nerve-end neuromas become abnormally excitable, and produce an ectopic discharge which is believed to contribute to paresthesias and pain associated with chronic nerve injury in man. Here we report that stimulation of injured nerves can alter this discharge, directly by antidromic invasion of...

journal_title：Brain research

authors： Lisney SJ,Devor M

更新日期：1987-07-07 00:00:00

abstract：:ERPs were acquired in the test phases of three memory experiments, where three classes of word were presented. These were: (i) words encountered in a prior study phase (studied words), (ii) words presented at test for the first time (new words), and (iii) new words repeated after a lag of 7-9 intervening words (repeat...

journal_title：Brain research

authors： Bridson NC,Fraser CS,Herron JE,Wilding EL

更新日期：2006-10-09 00:00:00

abstract：:Horseradish peroxidase (HRP) injected into developing limb buds of Xenopus laevis tadpoles is carried by retrograde axonal transport to the somata of motoneurones in the ventral horn. Small injection of 10% HRP were found to remain well localised to specified sites in the limb bud. Two types of labelled cells were fou...

journal_title：Brain research

authors： Lamb AH

更新日期：1977-10-07 00:00:00

abstract：:Post-hypoxic myoclonus is a movement disorder characterized by brief, sudden involuntary muscle jerks. Although the mechanism underlying this disorder remains unclear, earlier pharmacological studies indicated that aberrant activity of specific neuronal circuitry in the central nervous system causes this disorder. In ...

journal_title：Brain research

authors： Tai KK,Truong DD

更新日期：2005-10-19 00:00:00

abstract：:Axonal and glial cell development within rat optic nerve in which gliogenesis was altered by systemic injection of 5-azacytidine (5-AZ) was examined by quantitative electron microscopy. In neonatal (0-2 days) rat optic nerves, all fibers are premyelinated, and they exhibit a fairly uniform diameter (approximately 0.22...

journal_title：Brain research

authors： Black JA,Waxman SG,Ransom BR,Feliciano MD

更新日期：1986-08-13 00:00:00

abstract：:The aim of this study was to evaluate the effects of hypothermia on bilirubin-induced alterations in brain cell membrane function and energy metabolism in the developing brain. Thirty-seven newborn piglets were divided randomly into four groups: normothermic control (NC, n=9); hypothermic control (HC, n=7); normotherm...

journal_title：Brain research

authors： Park WS,Chang YS,Chung SH,Seo DW,Hong SH,Lee M

更新日期：2001-12-20 00:00:00

abstract：:Nerve growth factor (NGF) transported intraaxonally from the adrenergic nerve terminals in the iris to the cell bodies in the superior cervical ganglion resulted in an increase in the activity of the enzyme ornithine decarboxylase in the ganglion. This occurred in both six-day-old and adult rats with the relative effe...

journal_title：Brain research

authors： Hendry IA,Bonyhady R

更新日期：1980-10-27 00:00:00

abstract：:Prostaglandin E2 (PGE2) and proton are typical inflammatory mediators. They play a major role in pain processing and hypersensitivity through activating their cognate receptors expressed in terminals of nociceptive sensory neurons. However, it remains unclear whether there is an interaction between PGE2 receptors and ...

journal_title：Brain research

authors： Zhou YM,Wu L,Wei S,Jin Y,Liu TT,Qiu CY,Hu WP

更新日期：2019-12-01 00:00:00

abstract：:The adult rat retina was evaluated following surgical lesion and after transplantation of embryonic day 15 (E15) retinal tissue. While a surgical incision caused degeneration and ganglion cell death peripheral to lesion site, the addition of an embryonic retinal implant to the lesion site resulted in a reduction of th...

journal_title：Brain research

authors： Laedtke TW,Turner JE

更新日期：1989-10-23 00:00:00

abstract：:We have examined the influence of reducing conditions on the activity of group-I or -II metabotropic glutamate receptors. In cultured cerebellar granule cells or in hippocampal slices, the reducing agent dithiothreitol (DTT) inhibited the stimulation of polyphosphoinositide (PPI) hydrolysis elicited by group-I mGlu re...

journal_title：Brain research

authors： Copani A,Romano C,Di Giorgi Gerevini V,Nicosia A,Casabona G,Storto M,Mutel V,Nicoletti F

更新日期：2000-06-09 00:00:00

abstract：:Tubulin immunostaining of semi-thin sections after polyethylene glycol embedding was used in the tectal plate of the embryonic mouse at 10 days postmating to analyze the effects of cold treatment on the microtubules of the different cell types seen at this stage. Three sets of microtubules are observed. In the radiall...

journal_title：Brain research

authors： Cohen E,Binet S,Meininger V

更新日期：1987-12-01 00:00:00

abstract：:Experiments were performed to test the hypothesis that subarachnoid hemorrhage (SAH) causes functionally relevant perturbations of cyclooxygenase activity in cerebral arteries. Four groups of rabbits were formed: (I) controls; (II) sham injected animals (2 ml physiological solution in the cisterna magna); (III) SAH gr...

journal_title：Brain research

authors： Tran Dinh YR,Roche S,Debdi M,Seylaz J,Sercombe R

更新日期：1998-04-20 00:00:00

abstract：:It is well established that autonomic control of digestive function is modulated by central autonomic neurotransmission. In this context it has been shown that digestive function can be modulated by exogenous neuropeptides microinjected into specific brain sides. Furthermore, there is considerable evidence suggesting ...

journal_title：Brain research

authors： Tebbe JJ,Pasat IR,Mönnikes H,Ritter M,Kobelt P,Schäfer MK

更新日期：2005-03-02 00:00:00

abstract：:Recently, the gene encoding the cerebrovascular and neuritic plaque amyloid, a pathologic stigma of Alzheimer's disease (AD), has been molecularly cloned and mapped to human chromosome 21, band q21. Changes in the brains of individuals with trisomy 21 (Down syndrome, DS) over 35 years of age closely resemble AD neurop...

journal_title：Brain research

authors： Reeves RH,Robakis NK,Oster-Granite ML,Wisniewski HM,Coyle JT,Gearhart JD

更新日期：1987-09-01 00:00:00

abstract：:Amyloid beta protein (A beta), has been reported to be toxic to neurons in vitro. However, the molecular mechanism leading to neuronal death remains unknown. Here we report protective effects of phenothiazines, a class of neuroleptic agent, against A beta toxicity in primary cultures of rat cortical neurons and PC12 c...

journal_title：Brain research

authors： Ueda K,Yagami T,Asakura K,Kawasaki K

更新日期：1997-02-14 00:00:00

abstract：:The effects of the dopamine transporter (DAT) inhibitors cocaine and GBR12909 on DAT and dopamine D(2) receptors were evaluated in the brains under awake and isoflurane-anesthetized monkeys using high-resolution positron emission tomography (PET) in combination with microdialysis. The striatal DAT availability and dop...

journal_title：Brain research

authors： Tsukada H,Nishiyama S,Kakiuchi T,Ohba H,Sato K,Harada N,Nakanishi S

更新日期：1999-12-04 00:00:00

abstract：:Increases in extracellular potassium concentrations reliably increase burst rates in cultured fetal murine spinal cord networks. This effect could be mimicked by either blocking voltage-gated potassium conductances or facilitating excitatory synaptic interactions, but not by blocking specific calcium-dependent potassi...

journal_title：Brain research

authors： Rhoades BK,Gross GW

更新日期：1994-04-18 00:00:00

abstract：:The periaqueductal gray matter (PAG) has been implicated in a variety of different functions, including autonomic regulation. Chemical stimulation of the lateral PAG produces hypertension and tachycardia while activation of the ventrolateral PAG produces the opposite effect. While these effects are the result of alter...

journal_title：Brain research

authors： Farkas E,Jansen AS,Loewy AD

更新日期：1997-08-01 00:00:00