Pulsatile release of acetylcholinesterase from the substantia nigra following electrical stimulation of the striatum.

abstract：:Cholinergic mechanisms in the septohippocampal pathway contribute to several cognitive functions and impaired cholinergic transmission in this pathway may be related to the memory loss and dementia that accompanies normal aging and Alzheimer's disease and behavioral studies suggest that muscarinic mechanisms in the me...

journal_title：Brain research

authors： Liu W,Kumar A,Alreja M

更新日期：1998-09-14 00:00:00

abstract：:High salt intake is able to evoke neuroendocrine and autonomic responses that include vasopressin release and sympathoexcitation resulting in increasing in the arterial blood pressure (BP). The C1 neurons are a specific population of catecholaminergic neurons located in the RVLM region and they control BP under homeos...

journal_title：Brain research

authors： Ribeiro N,Martins Sá RW,Antunes VR

更新日期：2020-12-01 00:00:00

abstract：:The immunohistochemical distribution of Ca2+/calmodulin-dependent protein kinase II (CaM kinase II) alpha and beta isoforms in the rat forebrain was examined by using monoclonal antibodies specific to each isoform. The present study confirmed that alpha and beta immunoreactivities are localized only in neuronal elemen...

journal_title：Brain research

authors： Ochiishi T,Terashima T,Yamauchi T

更新日期：1994-10-03 00:00:00

abstract：:The light green cells (LGCs) in the central nervous system of the pond snail Lymnaea stagnalis form a homogeneous group of neuroendocrine cells that are involved in the control of growth and metabolism. These cells are inhibited by dopamine and the neuropeptides APGWamide, FMRFamide and GGSLFRFamide. Thus, the LGCs fo...

journal_title：Brain research

authors： van Tol-Steye H,Lodder JC,Planta RJ,van Heerikhuizen H,Kits KS

更新日期：1997-11-28 00:00:00

abstract：:When rat striatal membranes, photolabeled with [3H]dopamine under assay conditions similar to those used for dopamine-sensitive adenylate cyclase, were subjected to sodium dodecyl sulfate (SDS) polyacrylamide gel electrophoresis, several radioactively labeled bands appeared. Labeling of these bands was reduced in the ...

journal_title：Brain research

authors： Kuno T,Tanaka C

更新日期：1981-12-28 00:00:00

abstract：:The effects of sex steroids on immunoreactive beta-endorphin (EP) release from the rat hypothalamus in vitro were examined using a rat hypothalamic perifusion system and an EP RIA. Testosterone (1-100 ng/ml) and estradiol (10-100 pg/ml) stimulated EP release in a dose-dependent manner. Dehydroepiandrosterone (DHEA, 1-...

journal_title：Brain research

authors： Nakano Y,Suda T,Sumitomo T,Tozawa F,Demura H

更新日期：1991-07-05 00:00:00

abstract：:Chronic administration of guanethidine to adult rats induces a selective autoimmune adrenergic neuropathy. Physiological and biochemical features of this disorder in the peripheral nervous system were explored in young adult Sprague-Dawley rats given daily intraperitoneal guanethidine monosulfate for 5 weeks. Control ...

journal_title：Brain research

authors： Zochodne DW,Ward KK,Low PA

更新日期：1988-09-27 00:00:00

abstract：:The effects of caffeine ingestion and exposure to bright light, both separately and in combination, on salivary melatonin and tympanic temperature were assessed in humans. Four treatments during a 45.5 h sleep deprivation period were compared: Dim Light-Placebo, Dim Light-Caffeine, Bright Light-Placebo and Bright-Ligh...

journal_title：Brain research

authors： Wright KP Jr,Badia P,Myers BL,Plenzler SC,Hakel M

更新日期：1997-01-30 00:00:00

abstract：:We report the characterization of a new class of glutamate uptake inhibitors isolated from Phoneutria nigriventer venom. Glutamate transport activity was assayed in rat cerebrocortical synaptosomes by using [(3)H]-L-glutamate. PhTx4 inhibited glutamate uptake in a dose dependent manner. The IC(50) value obtained was 2...

journal_title：Brain research

authors： Mafra RA,Figueiredo SG,Diniz CR,Cordeiro MN,Cruz JD,De Lima ME

更新日期：1999-06-12 00:00:00

abstract：:Occipital cortex of 19-day-old fetal rats was dissociated and cultured in vitro for 2-5 weeks in horse serum supplemented Eagle's MEM. The outgrowing neurons rapidly formed a dense network which started to degenerate after 3 weeks in vitro. By means of electron microscopy the numerical development of 6 different categ...

journal_title：Brain research

authors： Romijn HJ,Mud MT,Habets AM,Wolters PS

更新日期：1981-07-01 00:00:00

abstract：:Extracellular field recordings were made in CA1 in the hippocampal explant cultures in oxygenated artificial cerebrospinal fluid. Schaffer collaterals were stimulated with 1-s trains of 60 Hz pulses every 10 min. Seizures were reliably elicited with progressive lengthening over 1-2 h. D-APV, an N-methyl-D-aspartate (N...

journal_title：Brain research

authors： Shin C,Tamaki Y,Wilson JT,Butler L,Sakaguchi T

更新日期：1992-08-28 00:00:00

abstract：:We have previously reported progressive reactive astrocytes in the cerebellum of taiep rats, one of the most regions affected by demyelination, and activation of cerebellar glial cells in vitro. Based on the hypothesis that activated glial cells produce high levels of reactive nitrogen intermediates, we assessed the p...

journal_title：Brain research

authors： Leon-Chavez BA,Aguilar-Alonso P,Gonzalez-Barrios JA,Eguibar JR,Ugarte A,Brambila E,Ruiz-Arguelles A,Martinez-Fong D

更新日期：2006-11-22 00:00:00

abstract：:Previous studies have demonstrated that food restriction during lactation extends the length of lactational infertility in rats. In order to determine whether Neuropeptide Y (NPY) plays a role in the increased length of lactational infertility seen in food-restricted rats, NPY immunoreactivity in the arcuate nucleus o...

journal_title：Brain research

authors： Abizaid A,Walker CD,Woodside B

更新日期：1997-07-04 00:00:00

abstract：:Neurons with intrinsic pacemaker activity and presumed sympathoexcitatory function were recorded in rat tissue slices within the confines of the rostroventrolateral reticular nucleus (RVL). These cells were excited in dose-dependent fashion by arginine vasopressin (AVP, 10(8)-10(6) M) but not by oxytocin (up to 10(7) ...

journal_title：Brain research

authors： Sun MK,Guyenet PG

更新日期：1989-07-17 00:00:00

abstract：:The importance of particular genes in neuronal death following global cerebral ischemia can readily be studied in genetically modified mice provided a reliable model of ischemia is available. For that purpose, we developed a mouse model of global cerebral ischemia that induces consistent damage to different regions of...

journal_title：Brain research

authors： Olsson T,Wieloch T,Smith ML

更新日期：2003-08-29 00:00:00

abstract：:Reverse transcription-polymerase chain reaction demonstrated the expression of heme oxygenase-1 and heme oxygenase-2 (HO-2) mRNA in the cochlea, but the former was considered to be much lower than the latter. The HO-2-like immunoreactivity was observed mainly in supporting cells in the organ of Corti and in the spiral...

journal_title：Brain research

authors： Watanabe K,Oshima T,Kobayashi T,Ikeda K

更新日期：2003-03-14 00:00:00

abstract：:Electrical stimulation of the brain, particularly in the periventricular grey areas, caused long-lasting increases in behavioural escape thresholds to heating and mechanical stimuli applied to the facial region of the rat. The brain stimulation selectively suppressed responses to noxious stimuli. Responses to non-noxi...

journal_title：Brain research

authors： Cahusac PM,Morris R,Hill RG

更新日期：1995-11-27 00:00:00

abstract：:The colocalisation of neuropeptide Y (NPY)- and 5-hydroxytryptamine (5-HT)-immunoreactivities in intracardiac neurones in dissociated cultures from the atria and interatrial septum of newborn guinea pig heart was demonstrated by the sequential application of specific antisera which were visualised by two different flu...

journal_title：Brain research

authors： Hassall CJ,Burnstock G

更新日期：1987-09-29 00:00:00

abstract：:Binge-like ethanol treatment of septal neurons blunts GABAAR-mediated miniature postsynaptic currents (mPSCs), suggesting it arrests synaptic development. Ethanol may disrupt postsynaptic maturation by blunting feedback signaling through immature GABAARs. Here, the impact of ethanol on the sensitivity of mPSCs to zolp...

journal_title：Brain research

authors： DuBois DW,Trzeciakowski JP,Parrish AR,Frye GD

更新日期：2006-05-17 00:00:00

abstract：:Cellular distribution of the two forms of SERCA2 was examined in adult chicken brain. Four regions of the brain were analyzed with three immunological reagents: a monoclonal antibody that recognizes both forms of SERCA2, and two antisera which are specific for the two alternative forms, SERCA2b or SERCA2a. Cerebellar ...

journal_title：Brain research

authors： Campbell AM,Wuytack F,Fambrough DM

更新日期：1993-03-05 00:00:00

abstract：:The thalamic midline/intralaminar complex is part of the higher-order thalamus, which receives little sensory input, and instead forms extensive cortico-thalamo-cortical pathways. The midline thalamic nuclei connect with the medial prefrontal cortex and the medial temporal lobe. On the other hand, the intralaminar nuc...

journal_title：Brain research

authors： Silva Ade M,de Santana MA,Morais PL,de Sousa TB,Engelberth RC,Lucena EE,Campêlo CL,Cavalcante JS,Cavalcante JC,Costa MS,do Nascimento ES Jr

更新日期：2014-10-24 00:00:00

abstract：:Mitochondrial division inhibitor (mdivi-1), a selective inhibitor of a mitochondrial fission protein dynamin-related protein 1 (Drp1), has been shown to exert protective effects in heart and cerebral ischemia-reperfusion models. The present study was designed to investigate the beneficial effects of mdivi-1 against sp...

journal_title：Brain research

authors： Liu JM,Yi Z,Liu SZ,Chang JH,Dang XB,Li QY,Zhang YL

更新日期：2015-09-04 00:00:00

abstract：:Spontaneously firing units were recorded extracellularly from the hippocampus of anesthetized rats, and autocorrelograms were conventionally constructed. These conventional autocorrelograms were sorted into frequency-specific autocorrelograms according to the instantaneous firing frequency of the spike at Deltat=0, wh...

journal_title：Brain research

authors： Murata M,Kato N

更新日期：2007-02-16 00:00:00

abstract：:The effects of psychological stress on catecholamine and indoleamine metabolism were examined in various brain regions of rats. Psychologically stressed rats were exposed to emotional responses of foot-shocked rats, but were themselves prevented from receiving foot-shock. Psychological stress for 30 min resulted in si...

journal_title：Brain research

authors： Kaneyuki H,Yokoo H,Tsuda A,Yoshida M,Mizuki Y,Yamada M,Tanaka M

更新日期：1991-08-23 00:00:00

abstract：:The genomic response following brain ischemia is very complex and involves activation of both protective and detrimental signaling pathways. Immediate early genes (IEGs) represent the first wave of gene expression following ischemia and are induced in extensive regions of the ischemic brain including cerebral cortex a...

journal_title：Brain research

authors： Rickhag M,Teilum M,Wieloch T

更新日期：2007-06-02 00:00:00

abstract：:Cytosol androgen receptors were assayed in guinea pig brain and pituitary tissues, using [3H]R1881 as ligand. These receptors had an apparent Kd of 0.04 nM and were androgen-specific (R1881 greater than dihydrotestosterone greater than testosterone = estradiol greater than progesterone). Concentrations of cytosol andr...

journal_title：Brain research

authors： Bonneau M,Ahdieh HB,Thornton JE,Feder HH

更新日期：1987-06-09 00:00:00

abstract：:The selective dopaminergic antagonist ligands [3H]SCH 23390 and [3H]sulpiride were used to reveal autoradiographically dopamine D1 and D2 receptors, respectively, in brain sections from rats which had received unilateral 6-hydroxydopamine (6-OHDA) injections destroying ascending nigrostriatal neurones. The binding of ...

journal_title：Brain research

authors： Graham WC,Crossman AR,Woodruff GN

更新日期：1990-04-23 00:00:00

abstract：:The acute intravenous administration of high doses of methylprednisolone sodium succinate (15-90 mg/kg) to cats enhanced (Na+ + K+)-ATPase activity as much as 2-fold in synaptosomes prepared from lumbar spinal cord removed following drug administration. The effect was apparent within 5 min and was statistically signif...

journal_title：Brain research

authors： Braughler JM,Hall ED

更新日期：1981-08-31 00:00:00

abstract：:Injury of peripheral nerves often results in hyperalgesia (an increased sensitivity to painful stimuli). This hyperalgesia is mediated in part by sympathetic neurotransmitters. We examined the effect of neuropeptide Y (NPY), specific Y1 and Y2 agonists, and an NPY antagonist on peripheral hyperalgesia in rats whose sc...

journal_title：Brain research

authors： Tracey DJ,Romm MA,Yao NN

更新日期：1995-01-16 00:00:00

abstract：:Sensory fibers trapped in nerve-end neuromas become abnormally excitable, and produce an ectopic discharge which is believed to contribute to paresthesias and pain associated with chronic nerve injury in man. Here we report that stimulation of injured nerves can alter this discharge, directly by antidromic invasion of...

journal_title：Brain research

authors： Lisney SJ,Devor M

更新日期：1987-07-07 00:00:00