Hemispheric asymmetry in behavioral response to D1 and D2 receptor agonists in the nucleus accumbens.

abstract：:The lactating rat has been shown to lack a behavioral response and immediate early gene expression (cFos) in the hippocampus (Hipc) following intravenous or intracerebroventricular administration of an N-methyl-d-aspartate (NMDA) receptor agonist. The purpose of this study is to determine whether neurons in the Hipc h...

journal_title：Brain research

authors： Grove KL,Smith MS

更新日期：1998-12-14 00:00:00

abstract：:The localization of the receptor for apamin, a specific toxin for one class of sensitive Ca2+-dependent K+ channel, was studied in rat brain using an in vitro autoradiographic technique. Radiolabeled monoiodoapamin binds specifically to rat brain sections with a high affinity (Kd = 25 pM) to a single class of sites. A...

journal_title：Brain research

authors： Mourre C,Hugues M,Lazdunski M

更新日期：1986-09-24 00:00:00

abstract：:It has been demonstrated previously that kappa opioid receptor agonists, such as dynorphin, inhibit oxytocin secretion in the rat. To determine whether kappa agonists act directly on oxytocin-containing magnocellular neurons to inhibit hormone secretion, we utilized immunofluorescence to examine the cellular localizat...

journal_title：Brain research

authors： Smith MJ,Wise PM

更新日期：2001-04-13 00:00:00

abstract：:Vascular dysfunction is important in the pathogenesis of peripheral complications of diabetes. However, the effects of diabetes on cerebral blood flow and the role of vascular deficits in the pathogenesis of diabetic encephalopathy are still unknown. The present study examined whether experimental diabetes is associat...

journal_title：Brain research

authors： Manschot SM,Biessels GJ,Cameron NE,Cotter MA,Kamal A,Kappelle LJ,Gispen WH

更新日期：2003-03-21 00:00:00

abstract：:A role for glutamatergic signaling in the nucleus accumbens (NA) in both the expression and extinction of cocaine seeking has been suggested. The effects of extinction following cocaine self-administration on the expression and synaptosomal distribution of GluR1 and NMDAR1 glutamate receptor subunits in the NA shell a...

journal_title：Brain research

authors： Ghasemzadeh MB,Vasudevan P,Mueller CR,Seubert C,Mantsch JR

更新日期：2009-04-24 00:00:00

abstract：:The present study is a determination of the numbers of axons in the sural nerve and nerve to the medial gastrocnemius muscle following section and regeneration of the sciatic nerve in the rat. The data indicate that there is a significant increase in both myelinated and unmyelinated axons in the nerve to the medial ga...

journal_title：Brain research

authors： Jenq CB,Coggeshall RE

更新日期：1984-03-12 00:00:00

abstract：:This study determined baroreceptor reflex (BR) function in conscious rats which had received sham or electrolytic lesions of the anteroventral third ventricle (AV3V) 54-56 days previously. Resting mean arterial pressure (MAP) and heart rate (HR) values of the AV3V-lesion rats were similar to those of sham-lesion rats ...

journal_title：Brain research

authors： Lewis SJ,Whalen EJ,Beltz TG,Johnson AK

更新日期：1999-07-24 00:00:00

abstract：:Bone marrow-derived mesenchymal stem cells (BMSCs) are a promising source for cell-based treatment of brain injury, but the therapy of BMSCs is restricted by low cell survival. We examined whether nerve growth factor (NGF) improve BMSCs viability in the brain with Fimbria-Fornix lesion (FF). After transduction of NGF ...

journal_title：Brain research

authors： Leng SL,Fan WG,Qu HG,Xu SC,Zhong WY,Zhang WY,Zeng JQ,Long DH,He HW

更新日期：2009-01-19 00:00:00

abstract：:Sensitisation to the behavioural effects of amphetamine, a phenomenon which appears to involve the potentiation of excitatory amino acid (EAA)-mediated transmission at the level of dopaminergic (DA) neurons in the ventral tegmental area (the A10 cell group), is known to be affected by corticosteroid manipulations. Sin...

journal_title：Brain research

authors： Overton PG,Tong ZY,Brain PF,Clark D

更新日期：1996-10-21 00:00:00

abstract：:Distribution and time course of the occurrence of "dark" neurons were compared with the EEG activity and behavior of rats during 4-aminopyridine (4-AP) induced epileptic seizures. A crystal of the K(+) channel blocker 4-AP (0.5 mg/kg) was placed onto the exposed parieto-occipital cortex of Halothane-anesthetized rats ...

journal_title：Brain research

authors： Baracskay P,Szepesi Z,Orbán G,Juhász G,Czurkó A

更新日期：2008-09-04 00:00:00

abstract：:We have previously demonstrated that ibotenate (IBO)-stimulated polyphosphoinositide (PPI) hydrolysis is increased for a long period in the amygdala/pyriform cortex (AM/PC) of amygdala (AM)- and hippocampal (HIPP)-kindled rats. This finding indicates that enhanced function of the PPI-coupled excitatory amino acid (EAA...

journal_title：Brain research

authors： Akiyama K,Daigen A,Yamada N,Itoh T,Kohira I,Ujike H,Otsuki S

更新日期：1992-01-08 00:00:00

abstract：:Oxidative stress has been implicated as a pathogenic mediator of neuronal perikarya cell death. Axons and oligodendrocytes, components of white matter, could also be vulnerable to oxidative damage. An experimental model of oxidative stress was induced by systemic injection of 3-nitropropionic acid (3-NPA). Animals rec...

journal_title：Brain research

authors： McCracken E,Dewar D,Hunter AJ

更新日期：2001-02-23 00:00:00

abstract：:Glycine is taken up twice as rapidly by neurons R3-R14 as by other identified neurons in the Aplysia parietovisceral ganglion. Earlier studies had shown that R3-R14 have much higher glycine concentrations than other Aplysia neurons. Most of the glycine taken up by R3-R14 was biochemically untransformed for at least 1 ...

journal_title：Brain research

authors： McAdoo DJ,Iliffe TM,Price CH,Novak RA

更新日期：1978-10-06 00:00:00

abstract：:To gain insight into ATP-binding cassette transporter A1 (ABCA1) function and its potential role in AD pathology, we analyzed the expression of the cholesterol transporter ABCA1 in postmortem hippocampus from persons at different stages of dementia and AD associated neuropathology relative to cognitively intact normal...

journal_title：Brain research

authors： Akram A,Schmeidler J,Katsel P,Hof PR,Haroutunian V

更新日期：2010-03-08 00:00:00

abstract：:Glucocorticoids bind with high affinity to intracellular receptors located in high density within discrete regions of the rodent and primate brain. The binding of [3H]corticosterone was compared in the brains of male vs female rats. The number and affinity of cytosol receptors in the hippocampus and hypothalamus were ...

journal_title：Brain research

authors： Turner BB,Weaver DA

更新日期：1985-09-16 00:00:00

abstract：:C57BL/6J (B6) and DBA/2J (D2) mice have been characterized previously as seizure-resistant and seizure-sensitive, respectively, a distinction based primarily upon a differential response to the convulsant effects of various drugs. In the present study, electroconvulsive shock (ECS) was used to assess maximal electrosh...

journal_title：Brain research

authors： Ferraro TN,Golden GT,Snyder R,Laibinis M,Smith GG,Buono RJ,Berrettini WH

更新日期：1998-11-30 00:00:00

abstract：:The protein composition of subcellular fractions of the cerebella of normal and weaver, staggerer and nervous mutant mice and of X-irradiated rats are studied by polyacrylamide gel electrophoresis in sodium dodecyl sulphate. The patterns observed are compared with those of granular and Purkinje cells purified from rat...

journal_title：Brain research

authors： Mallet J,Huchet M,Pougeois R,Changeux JP

更新日期：1976-02-20 00:00:00

abstract：:Repeated exposure to stressful stimuli or psychostimulants increases sensitivity to the motoric effects of these drugs, i.e. behavioral sensitization. The objective of the present experiment was to determine the interaction between factors that modulate psychostimulant sensitivity, i.e. sex and circulating gonadal hor...

journal_title：Brain research

authors： Haney M,Castanon N,Cador M,Le Moal M,Mormède P

更新日期：1994-05-09 00:00:00

abstract：:The prognosis of patients with malignant glioma remains extremely poor despite surgery and improvements in radio- and chemo-therapies. We recently showed that marrow-isolated adult mutilineage inducible (MIAMI) cells, a subpopulation of human mesenchymal stromal cells (MSCs), can serve as cellular carriers of drug-loa...

journal_title：Brain research

authors： Roger M,Clavreul A,Sindji L,Chassevent A,Schiller PC,Montero-Menei CN,Menei P

更新日期：2012-09-14 00:00:00

abstract：:Thyrotropin-releasing hormone (TRH) immunoreactivity in rat tissue was assayed using a new reversed-phase, ion-pair, high-pressure liquid chromatography (HPLC) method for separating TRH from its analogs. Virtually all of the TRH immunoreactivity in hypothalamus, brain stem, preoptic area, septum, striatum, frontal cor...

journal_title：Brain research

authors： Spindel E,Wurtman RJ

更新日期：1980-11-17 00:00:00

abstract：:The light green cells (LGCs) in the central nervous system of the pond snail Lymnaea stagnalis form a homogeneous group of neuroendocrine cells that are involved in the control of growth and metabolism. These cells are inhibited by dopamine and the neuropeptides APGWamide, FMRFamide and GGSLFRFamide. Thus, the LGCs fo...

journal_title：Brain research

authors： van Tol-Steye H,Lodder JC,Planta RJ,van Heerikhuizen H,Kits KS

更新日期：1997-11-28 00:00:00

abstract：:Enkephalin immunoreactive neurons within the nucleus tractus solitarius (NTS) were found to project to the parabrachial nucleus of the cat with the use of a combination of immunohistochemistry and retrograde transport of horseradish peroxidase. Double labelled neurons were located in the medial, parvocellular and comm...

journal_title：Brain research

authors： Maley BE,Panneton WM

更新日期：1988-03-01 00:00:00

abstract：:A decrease in the number of neuronal profiles in the isocortex of man may be observed on microscopic sections in aging and in degenerative diseases such as Alzheimer's disease. It can be the consequence of a loss of neurons per unit volume or of a reduction of the neuronal volume (i.e. pseudo-loss). This latter possib...

journal_title：Brain research

authors： Duyckaerts C,Llamas E,Delaère P,Miele P,Hauw JJ

更新日期：1989-12-11 00:00:00

abstract：:The regional hemodynamic basis of the cardiovascular response to acute noise stress in spontaneously hypertensive (SHR) and Wistar-Kyoto (WKY) rats and the role of the central amygdaloid nucleus in mediating this response was investigated. Using the pulsed Doppler flow probe technique it was determined that in respons...

journal_title：Brain research

authors： Galeno TM,Van Hoesen GW,Brody MJ

更新日期：1984-01-23 00:00:00

abstract：:Converging evidence implicates alterations in multiple signaling pathways in the etiology of schizophrenia. Previously, these studies were limited to the analysis of one or a few phosphoproteins at a time. Here, we use a novel kinase array platform to simultaneously investigate the convergence of multiple signaling ca...

journal_title：Brain research

authors： McGuire JL,Hammond JH,Yates SD,Chen D,Haroutunian V,Meador-Woodruff JH,McCullumsmith RE

更新日期：2014-06-03 00:00:00

abstract：:Transient global cerebral ischemia has been shown to induce marked changes in the polyamine pathway with a significant increase in putrescine, the product of the ornithine decarboxylase reaction. This study examined the relationship between tissue and extracellular polyamines and regional cerebral blood flow and brain...

journal_title：Brain research

authors： Başkaya MK,Rao AM,Dogan A,Donaldson D,Gellin G,Dempsey RJ

更新日期：1997-01-09 00:00:00

abstract：:The aim of this paper was to examine if pre- and neonatal exposure that results in lead (Pb) concentration below 'safe level' (10 μg/dL) in offspring blood may cause disruption of the pro/antioxidant balance in the developing rat brain. We studied oxidative stress intensity (malondialdehyde (MDA) concentration) as wel...

journal_title：Brain research

authors： Baranowska-Bosiacka I,Gutowska I,Marchlewicz M,Marchetti C,Kurzawski M,Dziedziejko V,Kolasa A,Olszewska M,Rybicka M,Safranow K,Nowacki P,Wiszniewska B,Chlubek D

更新日期：2012-01-30 00:00:00

abstract：:The same cells in both the intact retina and retinal cultures of the rabbit retina take up exogenous serotonin or 5,7-dihydroxytryptamine. Both substances can be localised by immunohistochemistry using a monoclonal antibody directed against serotonin. The 5,7-dihydroxytryptamine can also be revealed directly in both f...

journal_title：Brain research

authors： Osborne NN,Beaton DW

更新日期：1986-09-10 00:00:00

abstract：:Cytogenesis in the kitten retina has been investigated with [3H]thymidine autoradiography and a stain for mitotic figures. The nuclei of cells in S-phase are located adjacent to the inner margin of the cytoblast layer, near the inner plexiform layer. The nuclei then migrate toward the outer limiting membrane (OLM) to ...

journal_title：Brain research

authors： Robinson SR,Rapaport DH,Stone J

更新日期：1985-03-01 00:00:00

abstract：:One-day-old chicks were exposed for 60 min to either an imprinting stimulus or a dark-box. They were killed at 0, 1, 6 or 12 h after the end of this treatment, and the activities of acetylcholinesterase (AChE) and choline acetyltransferase (ChAc) assayed in the forebrain roof, forebrain base and midbrain. The activity...

journal_title：Brain research

authors： Haywood J,Hambley J,Rose S

更新日期：1975-07-11 00:00:00