Unilateral deficits induced in rats by MPP+ are markedly reduced by an N-terminal peptide fragment of dopamine-releasing protein.

abstract：:The effects of caffeine ingestion and exposure to bright light, both separately and in combination, on salivary melatonin and tympanic temperature were assessed in humans. Four treatments during a 45.5 h sleep deprivation period were compared: Dim Light-Placebo, Dim Light-Caffeine, Bright Light-Placebo and Bright-Ligh...

journal_title：Brain research

authors： Wright KP Jr,Badia P,Myers BL,Plenzler SC,Hakel M

更新日期：1997-01-30 00:00:00

abstract：:Superfusion of the hepatic portal vein with hypertonic saline solutions increases the electrical activity of the hypothalamo-neurohypophysial tract. Bilateral cervical vagotomy had no effect on this response in all rats studied. Section of the hepatic branch of the vagus abolished the hypothalamic response in only two...

journal_title：Brain research

authors： Vallet PG,Baertschi AJ

更新日期：1982-05-06 00:00:00

abstract：:GPR56, a member of the G-protein-coupled receptor family, plays a role in the formation of the frontal and parietal brain lobes and cortical lamination in the embryonic stage. A recent report indicated the existence of GPR56 transcripts in the subventricular zone (SVZ) and hippocampal subgranular zone (SGZ) of the adu...

journal_title：Brain research

authors： Suzuki G,Kanda Y,Nibuya M,Hiramoto T,Tanaka T,Shimizu K,Watanabe Y,Nomura S

更新日期：2007-12-05 00:00:00

abstract：:We have previously shown that the HSV-2 anti-apoptotic protein ICP10PK is delivered by the replication incompetent virus mutant DeltaRR and prevents kainic acid (KA)-induced epileptiform seizures and neuronal cell loss in the mouse and rat models of temporal lobe epilepsy. The present studies used DeltaRR and the ICP1...

journal_title：Brain research

authors： Gober MD,Laing JM,Thompson SM,Aurelian L

更新日期：2006-11-13 00:00:00

abstract：:Although Rolling mouse Nagoya (RMN) has been considered to demonstrate cerebellar dysfunction, our previous metabolic and electrophysiological studies also revealed a dysfunction of the basal ganglia, with the presumable primary site of dysfunction being the striatum. In the present study, we investigated the neuroche...

journal_title：Brain research

authors： Taniwaki T,Shinoda H,Kaseda Y,Kato M,Goto I

更新日期：1996-04-01 00:00:00

abstract：:To determine if cell death participates in the regulation of cell number between interconnecting populations of the neocortex, we sectioned the corpus callosum of neonatal hamsters, thus depriving callosally projecting cells of their normal targets and callosally-recipient cells of their normal afference. The numbers ...

journal_title：Brain research

authors： Windrem MS,Jan de Beur S,Finlay BL

更新日期：1988-09-01 00:00:00

abstract：:Increased permeability of the brain-blood barrier (BBB) in the piriform cortex (PC) has been reported in various animal models of temporal lobe epilepsy. Since BBB disruption induced by epileptogenic insult has not fully clarified, we attempted to determine whether changes in BBB-related molecules are associated with ...

journal_title：Brain research

authors： Sheen SH,Kim JE,Ryu HJ,Yang Y,Choi KC,Kang TC

更新日期：2011-01-19 00:00:00

abstract：:Female rats were subjected to unilateral left or right, bilateral, or sham ablation of the cerebral cortex. Eight weeks after surgery, the rats were sacrificed by decapitation and spleen cells were grown in culture for 96 h in the presence or absence of the T-cell mitogen concanavalin A or the B-cell mitogen lipopolys...

journal_title：Brain research

authors： LaHoste GJ,Neveu PJ,Mormède P,Le Moal M

更新日期：1989-03-27 00:00:00

abstract：:We investigated the effect of high dose tetrodotoxin (TTX) on microdialysis measurements of extracellular striatal glutamate and dopamine in normal female rats. Both halothane-anesthetized rats with acutely implanted microdialysis probes and awake rats with microdialysis probes implanted for 24 h were tested. Glutamat...

journal_title：Brain research

authors： Shiraishi M,Kamiyama Y,Hüttemeier PC,Benveniste H

更新日期：1997-06-13 00:00:00

abstract：:Awake, intact monkeys were trained to perform discrete flexion or extension movements of the hand about the wrist in response to visual signals. The object of the movement was to align a cursor, coupled to a manipulandum, on a target line. Cursor and target lines are displayed on a video monitor placed in front of the...

journal_title：Brain research

authors： Murphy JT,Kwan HC,MacKay WA,Wong YC

更新日期：1982-03-25 00:00:00

abstract：:To identify whether altered expressions of voltage gated Ca(2+) channel (VGCC) are linked to inhibitory transmission abnormalities in the gerbil hippocampus, we investigated the effects of GABA receptor or somatostatin receptor (SST) antagonists/agonists on VGCC immunoreactivity in vivo. VGCC immunoreactivities in the...

journal_title：Brain research

authors： Kim DS,Kwak SE,Kim JE,Kim JS,Won MH,Kang TC

更新日期：2006-10-18 00:00:00

abstract：:The possibility has been mentioned that a change in the structure is responsible for the deviant behavioral activity of gamma-endorphin in extracts of postmortem brain and pituitary gland samples of schizophrenic patients. This paper describes the investigation of this possibility by means of: amino acid composition a...

journal_title：Brain research

authors： Bovenberg RA,Burbach JP,Wiegant VM,Veeneman GH,van Boom JH,Baas PD,Jansz HS,de Wied D

更新日期：1986-06-18 00:00:00

abstract：:Co-activation of group I metabotropic glutamate (mGlu) receptors and adenosine receptors resulted in an augmented cyclic AMP response in primary cultures of rat striatal neurones. L-glutamate and the selective group I agonist, (S)-dihydroxyphenylglycine (S-DHPG) evoked concentration-dependent potentiations of cyclic A...

journal_title：Brain research

authors： Cartmell J,Goepfert F,Knoflach F,Pink JR,Bleuel Z,Richards JG,Schaffhauser H,Kemp JA,Wichmann J,Mutel V

更新日期：1998-04-27 00:00:00

abstract：:Neovascularization within syngeneic rat fetal neocortical grafts transplanted into a previously prepared cavity in the cerebral cortex was studied 1 to 3 months after transplantation, utilizing scanning electron microscopy of vascular corrosion casts. The grafts were easily identified and the outer surface of the graf...

journal_title：Brain research

authors： Miyoshi Y,Date I,Ohmoto T

更新日期：1995-05-29 00:00:00

abstract：:The effects of acetylcholine (ACh) and physostigmine (PHY) on thoracic ganglion neurons of Locusta migratoria were investigated using whole-cell and cell-attached voltage clamp. ACh activated whole-cell currents with variable amplitudes, time course and ion channel block between cells, suggesting differential expressi...

journal_title：Brain research

authors： van den Beukel I,van Kleef RG,Zwart R,Oortgiesen M

更新日期：1998-04-13 00:00:00

abstract：:Protease-activated receptors (PARs), G-protein-coupled receptors, are widely expressed in various tissues, where they participate in physiological and pathological processes, such as hemostasis, proliferation, tissue repair, and inflammation. Recently, we found that PARs were upregulated in the rat retina following op...

journal_title：Brain research

authors： Luo W,Wang Y,Reiser G

更新日期：2005-06-21 00:00:00

abstract：:This study determined whether macrophage inflammatory protein-1beta (MIP-1beta) plays a role in the hyperthermia caused by prostaglandin E2 (PGE2) given intracerebroventricularly (i.c.v.) in the rat. In these experiments, anti-murine MIP-1beta antibody (anti-MIP-1beta) was micro-injected in the anterior hypothalamic, ...

journal_title：Brain research

authors： Armengol JA,Benamar K,Fernández-Alonso A,Sancibrián M,Myers RD,Miñano FJ

更新日期：1997-02-14 00:00:00

abstract：:The effects of sodium valproate on extracellularly recorded spontaneous neuronal activity and its interaction with GABA-induced inhibition were assessed in the rat medial basal hypothalamus both in situ and in explant culture. In situ, valproate enhanced the spontaneous rate in 14 of 20 neurons sampled, 6 neurons were...

journal_title：Brain research

authors： Baldino F Jr,Geller HM

更新日期：1981-08-24 00:00:00

abstract：:Alcohol-preferring Alko, Alcohol (AA) rats with free access to food and water were taught to voluntarily consume 10% alcohol solution during 20-min sessions. After the drinking session, rats had elevated dopamine release (as reflected by 3-methoxytyramine concentrations) in the nucleus accumbens, olfactory tubercle, a...

journal_title：Brain research

authors： Honkanen A,Ahtee L,Korpi ER

更新日期：1997-11-07 00:00:00

abstract：:In the present study, we observed chronological changes of antioxidant-like protein 1 (AOP-1) in the gerbil hippocampal CA1 region after 5 min of transient forebrain ischemia using immunohistochemistry and western blot. AOP-1 was significantly altered in the CA1 region after transient ischemia. In the sham-operated gr...

journal_title：Brain research

authors： Hwang IK,Hua L,Yoo KY,Kim DW,Kang TC,Choi SY,Won MH,Kim DH

更新日期：2005-11-16 00:00:00

abstract：:The importance of particular genes in neuronal death following global cerebral ischemia can readily be studied in genetically modified mice provided a reliable model of ischemia is available. For that purpose, we developed a mouse model of global cerebral ischemia that induces consistent damage to different regions of...

journal_title：Brain research

authors： Olsson T,Wieloch T,Smith ML

更新日期：2003-08-29 00:00:00

abstract：:The dorsal vagal complex of the medulla oblongata is a key centre involved in the regulation of numerous autonomic functions, including cardiovascular control. Adenosine has been implicated as a potential neuromodulator of the baroreceptor reflex, and therefore the current study has investigated the presence and chara...

journal_title：Brain research

authors： Castillo-Meléndez M,Krstew E,Lawrence AJ,Jarrott B

更新日期：1994-07-25 00:00:00

abstract：:When rat striatal membranes, photolabeled with [3H]dopamine under assay conditions similar to those used for dopamine-sensitive adenylate cyclase, were subjected to sodium dodecyl sulfate (SDS) polyacrylamide gel electrophoresis, several radioactively labeled bands appeared. Labeling of these bands was reduced in the ...

journal_title：Brain research

authors： Kuno T,Tanaka C

更新日期：1981-12-28 00:00:00

abstract：:Venous capacitance plays an important role in the control of cardiac output. However, the central nervous system sites and neurochemical signals involved in modulating venous function remain to be fully elucidated. The hypothalamic paraventricular nucleus (PVN) is an important site modulating autonomic outflow to the ...

journal_title：Brain research

authors： Martin DS,Rodrigo MC,Egland MC,Barnes LU

更新日期：1997-05-09 00:00:00

abstract：:Dysfunction in the hypothalamic GABAergic system has been implicated in panic syndrome in humans. Furthermore, several studies have implicated the hypothalamus in the elaboration of pain modulation. Panic-prone states are able to be experimentally induced in laboratory animals to study this phenomenon. The aim of the ...

journal_title：Brain research

authors： Freitas RL,Uribe-Mariño A,Castiblanco-Urbina MA,Elias-Filho DH,Coimbra NC

更新日期：2009-12-11 00:00:00

abstract：:The nucleus accumbens and ventral pallidum receive dopamine (DA) projections from the mesencephalon. Although DA inputs to the nucleus accumbens are implicated in both locomotion and reward processes, little is known of the behavioural significance of DA in the ventral pallidum. These studies examined the effects of D...

journal_title：Brain research

authors： Fletcher PJ,Korth KM,Sabijan MS,DeSousa NJ

更新日期：1998-09-14 00:00:00

abstract：:For the evaluation of glutamatergic and GABAergic transmission during seizures, rat hippocampal CA1 and CA3 areas were separately assessed by brain microdialysis, and extracelluar glutamate and GABA were measured through the course of the seizures after a systemic administration of kainic acid (KA). The generalized co...

journal_title：Brain research

authors： Ding R,Asada H,Obata K

更新日期：1998-07-27 00:00:00

abstract：:The human IGF2 and H19 genes are imprinted in most normal tissues. Alterations of genomic imprinting or loss of imprinting (LOI) have been observed in a number of malignant tumors. Although LOI has been linked to tumorigenesis, loss of IGF2 imprinting has also been observed in choroid plexus and leptomeninges in norma...

journal_title：Brain research

authors： Pham NV,Nguyen MT,Hu JF,Vu TH,Hoffman AR

更新日期：1998-11-09 00:00:00

abstract：:The sometimes devastating mood swings of bipolar disorder are prevented by treatment with selected antiepileptic drugs, or with lithium. Abnormal membrane ion channel expression and excitability in brain neurons likely underlie bipolar disorder, but explaining therapeutic effects in these terms has faced an unresolved...

journal_title：Brain research

authors： Butler-Munro C,Coddington EJ,Shirley CH,Heyward PM

更新日期：2010-09-17 00:00:00

abstract：:DDT [1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane] is a potent neurotoxicant in both vertebrate and invertebrate species. We have previously reported that neonatal exposure to DDT affects the muscarinic cholinergic receptors (MAChR) in the cerebral cortex in the neonatal mouse, leading to permanent disturbances in th...

journal_title：Brain research

authors： Eriksson P,Ahlbom J,Fredriksson A

更新日期：1992-06-12 00:00:00