Abstract：
:Alcohol-preferring Alko, Alcohol (AA) rats with free access to food and water were taught to voluntarily consume 10% alcohol solution during 20-min sessions. After the drinking session, rats had elevated dopamine release (as reflected by 3-methoxytyramine concentrations) in the nucleus accumbens, olfactory tubercle, and caudate-putamen. When alcohol solution was replaced by plain water, dopamine release was increased only in the caudate-putamen, indicating selective activation of the mesolimbic dopaminergic pathway by alcohol.
journal_name
Brain Resjournal_title
Brain researchauthors
Honkanen A,Ahtee L,Korpi ERdoi
10.1016/s0006-8993(97)81705-2subject
Has Abstractpub_date
1997-11-07 00:00:00pages
207-10issue
1-2eissn
0006-8993issn
1872-6240pii
S0006-8993(97)81705-2journal_volume
774pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:The effects of midazolam, one of the most popular benzodiazepines, on synaptic transmissions were compared with intracellular recordings between CA1 pyramidal cells (CA1-PCs) and dentate gyrus granule cells (DG-GCs) in rat hippocampal slices. First, we studied the effects of midazolam on orthodromically evoked spikes,...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(97)00920-7
更新日期：1997-10-31 00:00:00
abstract：:Pretreatment with recombinant human interleukin-1 alpha (rhIL-1 alpha) 20 h before irradiation attenuates radiation-induced hyperthermia. Experiments were conducted to determine the role of antioxidant enzymes such as superoxide dismutase (SOD) and glutathione peroxidase (GSHPx) in rhIL-1 alpha-induced attenuation of ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)91576-e
更新日期：1993-03-19 00:00:00
abstract：:Two rat lines bred for kindling susceptibility were previously observed to engage in different behavioral strategies in tests of emotionality. In order to extend past research on defensive behaviors in these strains which largely used males, Fast- and Slow-kindling females were assessed for anxiety-like behaviors in a...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2008.08.090
更新日期：2008-11-13 00:00:00
abstract：:Following single injections of horseradish peroxidase (HRP) in the superior colliculus (SC) and [3H]proline in the striate cortex of rats, a close correspondence was observed in the topographical arrangements of extrastriate cortical fields of HRP retrograde label and of isotope anterograde label. These results suppor...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(82)90318-3
更新日期：1982-06-24 00:00:00
abstract：:The effect of thyrotropin releasing hormone (TRH) administered either subcutaneously (s.c.) or intracerebroventricularly (i.c.v.) on the analgesic and hypothermic actions of U-50,488H, a highly selective kappa-opiate agonist, was determined in male Swiss Webster mice. Intraperitoneal administration of U-50,488H (8-32 ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90144-c
更新日期：1993-10-15 00:00:00
abstract：:Antipsychotic drugs are the main treatment for schizophrenia, despite their adverse side effects and uncertain mode of action. Gene expression studies in the brains of rodents treated with antipsychotic drugs aim to uncover this mechanism and elucidate more specific targets for schizophrenia treatment. Previous expres...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2009.09.045
更新日期：2009-12-22 00:00:00
abstract：:After an intraventricular administration of colchicine, the arcuate nucleus of rat hypothalamus was examined light and electron microscopically by pre-embedding immunohistochemistry for somatostatin. The arcuate nucleus exhibited numerous immunoreactive cell bodies and dense networks of immunoreactive fibers. The fibe...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(83)90312-8
更新日期：1983-03-21 00:00:00
abstract：:Proliferating astrocytes and proliferating neuroblasts have been observed in the subgranular zone (SGZ) of the dentate gyrus (DG) in the hippocampus of adult rats under normal conditions. However, whether these proliferating cells are stimulated by running has not been determined. Using immunohistochemical techniques,...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2006.05.066
更新日期：2006-08-09 00:00:00
abstract：:The horizontal and vertical vestibulo ocular reflex (VOR) of head tilted (het) mutant mice was compared to C57BL/6 controls. Eye movements were recorded in darkness using a temporarily attached search coil. Contributions of semicircular canal versus otolith organ signals were investigated by providing a canal only (ve...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(03)02505-8
更新日期：2003-05-16 00:00:00
abstract：:A combination of electron microscopic autoradiography and immunocytochemistry was used to examine the connections between serotoninergic axons and dopaminergic neurons of the arcuate nucleus of the rat hypothalamus. The serotoninergic elements were identified after selective uptake of tritiated serotonin and the dopam...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)90841-3
更新日期：1986-02-05 00:00:00
abstract：:Immobilization of frogs for 1 h induces analgesia which is blocked but not reversed by low doses of naloxone. After 9 days of daily immobilization for 1 h, the treatment fails to cause analgesia thus indicating that tolerance has developed. Animals tolerant to immobilization-induced analgesia do not show cross-toleran...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(84)90073-8
更新日期：1984-04-02 00:00:00
abstract：:The disturbance of microcirculation following cerebral ischemia leads to an enlargement of cerebral infarct volume. Endogenous thrombin may play a role in this disturbance of microcirculation following cerebral ischemia. Therefore, the inhibition of thrombin may improve neurodegeneration and the accumulation of cerebr...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(01)02354-x
更新日期：2001-06-01 00:00:00
abstract：:Neural stem cells can be derived from the adult/embryonic nervous system as well as from more primitive embryonic stem cells but, because of the lack of specific markers, only their differentiated progeny can be characterized. We here report the presence of several endothelial and hematopoietic receptors (at protein a...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(01)03291-7
更新日期：2002-01-25 00:00:00
abstract：:Quantitative in vitro autoradiography was used to examine [3H]D-Ala2, MePhe4, Gly-015 enkephalin (DAGO) (mu-agonist) and [3H]diprenorphine (general opiate antagonist) binding sites in the hippocampal formation of young (6-8 months) and aged (25-28 months) Long-Evans rats. Age-related changes in these binding sites wer...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(95)01211-7
更新日期：1996-01-22 00:00:00
abstract：:It is now well documented that optogenetics brings to neuroscience a long sought-after foothold to study the causal role of millisecond-scale activity of genetically or anatomically defined populations of neurons. Progress is rapid, and, as evidenced by the work collected in this Special Issue, the possibilities of wh...
journal_title：Brain research
pub_type： 杂志文章,评审
doi：10.1016/j.brainres.2013.01.008
更新日期：2013-05-20 00:00:00
abstract：:Thyrotropin-releasing hormone (TRH)-like immunoreactivity was examined in the rat olfactory bulb by an immunohistochemical method using antiserum against the tripeptide TRH. TRH-immunoreactive neurons and neuronal processes were localized in both main and accessory olfactory bulb, including the glomerular layer, exter...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)90983-3
更新日期：1988-04-26 00:00:00
abstract：:Trisomy 21 (Down syndrome) results in abnormalities in electrical membrane properties of cultured human fetal dorsal root ganglion (DRG) neurons. Action potentials have faster rates of depolarization and repolarization, with decreased spike duration, compared to diploid neurons. In order to analyze the faster depolari...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)91372-n
更新日期：1990-03-05 00:00:00
abstract：:This study examined the effects of stria terminalis (ST) lesions on glucocorticoid-induced modulation of memory formation for inhibitory avoidance training and spatial learning in a water maze. Systemic (s.c.) posttraining injections of the glucocorticoid receptor agonist dexamethasone (0.3 or 1.0 mg/kg) enhanced memo...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(95)01305-9
更新日期：1996-02-19 00:00:00
abstract：:The light and electron microscopic localization of leucine-enkephalin-containing terminals in the facial nucleus of the rat were investigated by means of the peroxidase-antiperoxidase (PAP) immunocytochemical technique. By light microscopy, leucine-enkephalin-like immunoreactive (LEI) terminals were unevenly distribut...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(83)90517-6
更新日期：1983-09-05 00:00:00
abstract：:Serum-free aggregating cell cultures of fetal rat telencephalon grown in the presence of 3 ng/ml (5 X 10(-10) M) epidermal growth factor (EGF) until day 12 showed 2- to 3-fold increased activities in the two glial enzymes, glutamine synthetase (GLU-S) and 2',3'-cyclic nucleotide 3'-phosphohydrolase (CNPase). This effe...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(83)90222-5
更新日期：1983-12-01 00:00:00
abstract：:Chronic administration of guanethidine to adult rats induces a selective autoimmune adrenergic neuropathy. Physiological and biochemical features of this disorder in the peripheral nervous system were explored in young adult Sprague-Dawley rats given daily intraperitoneal guanethidine monosulfate for 5 weeks. Control ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)90720-2
更新日期：1988-09-27 00:00:00
abstract：:The retinotopic organization of the expanded projection to the ipsilateral colliculus was studied electrophysiologically in 12 adult albino rats with one eye removed at birth. For comparison, the contralateral projection was rather variable in the representation of the nasotemporal axis of the retina along the rostroc...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(84)90200-2
更新日期：1984-11-12 00:00:00
abstract：:Because considerable work has implicated the basal ganglia in oral-ingestive behavior, an assessment was made of the effects of trigeminal stimuli upon entopeduncular single units. Units wre recorded extracellularly in awake, paralyzed and locally anesthetized cats. The effects of two types of sensory input were teste...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(78)90194-4
更新日期：1978-02-10 00:00:00
abstract：BACKGROUND:Diminished dopaminergic neurotransmission contributes to decreased reward and negative eating behaviors in obesity. Bariatric surgery is the most effective therapy for obesity and rapidly reduces hunger and improves satiety through unknown mechanisms. We hypothesized that dopaminergic neurotransmission would...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2010.03.064
更新日期：2010-09-02 00:00:00
abstract：:Intracellular recordings from CA3b/c neurons in rat hippocampal slices showed that reduction of the extracellular Cl- concentration from 136 to 53 mM produced a positive (+10 mV) shift in the reversal potential of GABAergic inhibitory postsynaptic potentials (IPSPs). This shift was not significantly different from the...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)91068-2
更新日期：1988-03-29 00:00:00
abstract：:An intracerebral microdialysis technique was applied to study the effect of metabotropic glutamate receptor (mGluR) agonist on dopamine release in the striatum of methamphetamine (MAP)-sensitized rats. Rats were treated with MAP (1 mg/kg, i.p.) once daily for 6 consecutive days, followed by a 6-day withdrawal. Perfusi...
journal_title：Brain research
pub_type： 杂志文章
doi：
更新日期：1996-08-12 00:00:00
abstract：:Application of the cholinergic agonist, carbachol, produced theta-like rhythmical waveforms, recorded in the stratum moleculare of the dentate gyrus in the cat hippocampal formation slices. This effect of carbachol was antagonized by atropine but not D-tubocurarine. These results provide first direct evidence that the...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)90223-v
更新日期：1992-04-24 00:00:00
abstract：:Movement of fragmented DNA in dendrites of retinal neurons during the apoptotic cell death was investigated. The time-course of the movement of fragmented DNA in dendrites of retinal neurons undergoing apoptotic cell death induced by intravitreal N-methyl-d-aspartate (NMDA) injection were examined by in situ terminal ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2004.01.075
更新日期：2004-05-08 00:00:00
abstract：:The adult rat retina was evaluated following surgical lesion and after transplantation of embryonic day 15 (E15) retinal tissue. While a surgical incision caused degeneration and ganglion cell death peripheral to lesion site, the addition of an embryonic retinal implant to the lesion site resulted in a reduction of th...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)90300-4
更新日期：1989-10-23 00:00:00
abstract：:MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) produces symptoms similar to idiopathic Parkinson's disease in primates. A metabolite of MPTP, MPP+ (1-methyl-4-phenylpyridinium), is actively accumulated by dopaminergic (DA) terminals and selectively destroys nigrostriatal DA neurons. The mechanism of this effect r...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)90616-6
更新日期：1988-12-20 00:00:00
