Neuron-specific enolase-like immunoreactivity in inner hair cells but not outer hair cells in the guinea pig organ of Corti.

Abstract:

:Neuron-specific enolase (NSE) has been localized only in neurons and cells with characteristics of neurons. The immunocytochemical localization of NSE was examined in guinea pig cochleae to determine if hair cells, which have some neuronal characteristics, would show NSE-like immunoreactive labeling. NSE-like immunoreactivity was seen in inner hair cells but not in outer hair cells. This is the first report of NSE-like immunoreactivity in a receptor cell. NSE-like immunoreactivity was also seen in efferent fibers and terminals and in both type I and type II spiral ganglion cells. The finding of NSE-like immunoreactivity in inner but not outer cells adds to the number of differences found between them and may be related to differences in function and action.

journal_name

Brain Res

journal_title

Brain research

authors

Altschuler RA,Reeks KA,Marangos PJ,Fex J

doi

10.1016/0006-8993(85)91541-0

subject

Has Abstract

pub_date

1985-02-18 00:00:00

pages

379-84

issue

1-2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(85)91541-0

journal_volume

327

pub_type

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