Abstract：
:Emerging evidence that autophagy serves as a sweeper for toxic materials in the brain gives us new insight into the pathophysiology of neurodegenerative diseases. Autophagy is important for maintaining cellular homeostasis associated with metabolism. Some neurodegenerative diseases such as Alzheimer׳s and Parkinson׳s diseases are accompanied by altered metabolism and autophagy in the brain. In this review, we discuss how hormones and nutrients regulate autophagy in the brain and affect neurodegeneration. This article is part of a Special Issue entitled SI:Autophagy.
journal_name
Brain Resjournal_title
Brain researchauthors
Lim Y,Cho H,Kim EKdoi
10.1016/j.brainres.2016.02.049subject
Has Abstractpub_date
2016-10-15 00:00:00pages
158-165issue
Pt Beissn
0006-8993issn
1872-6240pii
S0006-8993(16)30120-2journal_volume
1649pub_type
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