Abstract:
:Group-housed Sprague-Dawley (SD) rats exposed for 1 h to 2,5-dihydro-2,4,5-trimethylthiazoline (TMT, a component of fox feces) did not display changes in hippocampal serotonin (5-HT) metabolism and [3H]5-HT reuptake, compared to water or butyric acid. Such an observation extended to isolated SD and Fischer 344 rats. When group-housed SD rats were tested 1 week after a 1-h exposure to TMT, hippocampal 5-HT metabolism, [3H]5-HT reuptake, and [3H]paroxetine binding at the 5-HT transporter remained unchanged. This study questions TMT as a specific predatory stimulus as both butyric acid and TMT increased plasma corticosterone levels whilst leaving intact open field behaviour (at least in group-housed SD rats).
journal_name
Brain Resjournal_title
Brain researchauthors
Dias Soares D,Fernandez F,Aguerre S,Foury A,Mormède P,Chaouloff Fdoi
10.1016/s0006-8993(02)03944-6subject
Has Abstractpub_date
2003-01-24 00:00:00pages
166-70issue
1eissn
0006-8993issn
1872-6240pii
S0006899302039446journal_volume
961pub_type
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