Chronic ingestion of ethanol increases the number of Ca2+ channels of hippocampal neurons of long-sleep but not short-sleep mice.

abstract：:Recent studies, which have shown an increase of plasma vasopressin (VP) in experimental motion sickness and the efficacy of VP antagonists for motion sickness, suggest an important role of VP in the development of vestibulo-autonomic responses. We have recently found evidence of the co-existence of vasopressinergic ne...

journal_title：Brain research

authors： Horii A,Koike K,Uno A,Uno Y,Kubo T

更新日期：2001-09-28 00:00:00

abstract：:The effect of high acetaldehyde (ACe) on acetylcholine (ACh) release was studied in vivo in the medial frontal cortex (mfc) of freely moving rats using brain microdialysis coupled with high performance liquid chromatography and an electrochemical detector. Ethanol (EtOH) and ACe concentrations were quantified simultan...

journal_title：Brain research

authors： Jamal M,Ameno K,Wang W,Kumihashi M,Ameno S,Ikuo U,Shinji A,Ijiri I

更新日期：2005-03-28 00:00:00

abstract：:Affective disorders and memory impairments precede the classical motor symptoms seen in Parkinson's disease (PD) and the currently approved antiparkinsonian agents do not alleviate the non-motor symptoms as well as the underlying dopaminergic neuron degeneration. On the other hand, there is increasing evidence that in...

journal_title：Brain research

authors： Castro AA,Wiemes BP,Matheus FC,Lapa FR,Viola GG,Santos AR,Tasca CI,Prediger RD

更新日期：2013-06-04 00:00:00

abstract：:Using a co-culture model, we showed that diffusible factors from arcuate nucleus (AN) specifically increased the number and the size of hypothalamic neurons producing melanin-concentrating hormone (MCH). In this model neurite outgrowth and contacts between MCH neurons and dopaminergic neurons were also prominently inc...

journal_title：Brain research

authors： Compagnone N,Fellmann D,Bugnon C,Jaquemard C

更新日期：1993-11-19 00:00:00

abstract：:Monoclonal antibodies were produced against tyrosine hydroxylase (TH), the enzyme catalyzing the rate limiting step in catecholamine neurotransmitter synthesis. An enzyme linked immunosorbant assay was used to detect the presence of specific antibody in culture. Specificity of the antibodies is characterized. These mo...

journal_title：Brain research

authors： Ross ME,Reis DJ,Joh TH

更新日期：1981-03-16 00:00:00

abstract：:The core neuropsychological processes underlying post-traumatic stress disorder (PTSD) have yet to be elucidated, and the association between anatomical and functional deficits in PTSD remains largely unknown. The aim of our study was to investigate the alterations in cortical thickness and amplitude of low-frequency ...

journal_title：Brain research

authors： Bing X,Ming-Guo Q,Ye Z,Jing-Na Z,Min L,Han C,Yu Z,Jia-Jia Z,Jian W,Wei C,Han-Jian D,Shao-Xiang Z

更新日期：2013-01-15 00:00:00

abstract：:Mild acute hypertension was induced in rats pharmacologically and non-pharmacologically with metaraminol, angiotensin II or bilateral vagotomy. The extraction fraction of water (Ew) was measured in both hypertensive and normotensive animals. It was demonstrated that cerebral blood flow did not change during hypertensi...

journal_title：Brain research

authors： Ling RT,Hartman BK,Clark HB

更新日期：1984-08-13 00:00:00

abstract：:The intercollicular pathway of the rat was studied using autoradiographic (ARG) and horseradish peroxidase (HRP) tracing techniques. The HRP experiments demonstrated that the cells of origin of the intertectal pathway were located primarily in the rostral stratum griseum intermediale ( SGI ), stratum album intermedium...

journal_title：Brain research

authors： Yamasaki DS,Krauthamer G,Rhoades RW

更新日期：1984-05-23 00:00:00

abstract：:We have investigated, in 9 normal subjects, the time course of amplitude changes in the automatic long latency stretch reflex of wrist flexors during the preparatory period as a function of the precued direction of hand movement. Subjects maintained right hand position against a weak force and learned to compensate pr...

journal_title：Brain research

authors： Bonnet M

更新日期：1983-11-28 00:00:00

abstract：:Electrical stimulation of the sural nerve (SN) revealed input from sural nerve afferents to L6 and L7 dorsal horn neurons that were not apparent using natural mechanical stimuli, especially in cells with variable latency responses to SN stimulation. Nearly all (31/32) cells that had reliable, fixed latency responses t...

journal_title：Brain research

authors： Pubols LM,Foglesong ME,Vahle-Hinz C

更新日期：1986-04-16 00:00:00

abstract：:Unilateral visual cortex ablations in neonatal rabbits produced no detectable loss of ganglion cells in the contralateral retina following a survival period of 3, 4 or 8 months. Analysis of neuron size distributions and neuron densities from whole-mounted retinas indicate that transneuronal retrograde degeneration doe...

journal_title：Brain research

authors： Wilkes M,Zingaro G,Murphy EH

更新日期：1985-08-01 00:00:00

abstract：:As an approach to understanding why central neurons fail to regenerate, we have studied the response to proximal axotomy of transcallosal neurons of the cerebral cortex of the mouse. Anatomical studies have indicated only very slight regenerative responses by this population of cortical neurons. To further examine the...

journal_title：Brain research

authors： Elliott EJ,Parks DA,Fishman PS

更新日期：1997-05-02 00:00:00

abstract：:Antibodies were raised in rabbits against the neuropeptide N-acetyl-L-aspartyl-L-glutamate (NAAG) coupled to bovine serum albumin via a carbodiimide linkage. One of these rabbit antisera, which preferentially recognizes coupled NAAG-like immunoreactivity (LIR), has been previously used to immunocytochemically localize...

journal_title：Brain research

authors： Guarda AS,Robinson MB,Ory-Lavollée L,Forloni GL,Blakely RD,Coyle JT

更新日期：1988-06-01 00:00:00

abstract：:The present study was designed to assess the effect of protein kinase C (PKC) and cAMP-dependent protein kinase (PKA) on desensitization of Torpedo acetylcholine (ACh) receptors by analyzing summated macroscopic currents in an outside-out patch-clamp configuration. Normal ACh receptors desensitized with a fast (6 ms) ...

journal_title：Brain research

authors： Nishizaki T,Sumikawa K

更新日期：1998-11-23 00:00:00

abstract：:The functional organization of projections from the cerebellar subcortical nuclei to the motor cortex through the nucleus ventralis lateralis (VL) of the thalamus was studied using tungsten microelectrodes for stimulation and recordings in acute and chronic cats. The following results were obtained. (1) Microstimulati...

journal_title：Brain research

authors： Asanuma H,Hunsperger RW

更新日期：1975-11-07 00:00:00

abstract：:Previously, we have shown that intracisternal (i.c.) administration of beta-endorphin suppresses brain and liver DNA synthesis in rat pups. This finding is consistent with the view that endogenous CNS beta-endorphin plays an important role in controlling postnatal growth. Recent evidence suggests that brain CCK8, the ...

journal_title：Brain research

authors： Bartolome JV,Lorber BA,Bartolome MB

更新日期：1994-10-24 00:00:00

abstract：OBJECTIVE:There is an increasing interest concerning the contribution of astrocytes to the intrinsic bioremediation of ischemic brain injury. The aim of this work was to disclose the effects and mechanism of dexmedetomidine (DEX) on the apoptosis of astrocytes under oxygen glucose deprivation (OGD) condition. METHODS:...

journal_title：Brain research

authors： Feng P,Zhang A,Su M,Cai H,Wang X,Zhang Y

更新日期：2021-01-01 00:00:00

abstract：:Ovine corticotropin releasing factor (CRF) given intracerebroventricularly to rhesus monkeys at doses of 0.1-1 microgram/kg activates the pituitary-adrenal axis. The increases of plasma cortisol concentrations after intraventricular injection of CRF were similar to those observed after intravenous administration of th...

journal_title：Brain research

authors： Rock JP,Oldfield EH,Schulte HM,Gold PW,Kornblith PL,Loriaux L,Chrousos GP

更新日期：1984-12-10 00:00:00

abstract：:There is evidence that D1 and D2 dopamine receptor subtypes coexist at the cellular level in the striatum and act synergistically to mediate the effects of dopamine. Other data suggest that these receptor subtypes are largely segregated in different striatal projection pathways. We used in situ hybridization in serial...

journal_title：Brain research

authors： Lester J,Fink S,Aronin N,DiFiglia M

更新日期：1993-09-03 00:00:00

abstract：:An extensive exploration of the discriminating properties of olfactory receptors cells has been conducted in our laboratory through the statistical processing of single cell responses recorded in the frog's olfactory epithelium. Similarities between odorant stimulating properties could be demonstrated by comparing the...

journal_title：Brain research

authors： Sicard G,Holley A

更新日期：1984-02-06 00:00:00

abstract：:The effects of left and right prefrontal cortical dopamine (DA) depletion on circling behavior, stress-escape behavior and subcortical DA function were examined in rats exhibiting left or right turning biases. 6-Hydroxydopamine lesions of the medial prefrontal cortex (PFC) caused significant DA depletions when assesse...

journal_title：Brain research

authors： Carlson JN,Visker KE,Keller RW Jr,Glick SD

更新日期：1996-03-04 00:00:00

abstract：:Beta-amyloid (Abeta) peptides, the major component of senile plaques in brains of patients with Alzheimer's disease (AD), were found in the low pH organelles (i.e. endosome/lysosome) of cultured neuronal cells. Since acidic pH values have been shown to promote the self-assembly of Abetas, which seems to be a prerequis...

journal_title：Brain research

authors： Su Y,Chang PT

更新日期：2001-03-02 00:00:00

abstract：:In intracellular recordings from the CA1 region of the hippocampal slice preparation, an infrequent cell type different from the predominant pyramidal cell has been characterized. The cells have very brief spikes, hyperpolarizing after-potentials, and tend to fire at a high spontaneous rate; unitary synaptic potential...

journal_title：Brain research

authors： Schwartzkroin PA,Mathers LH

更新日期：1978-11-17 00:00:00

abstract：:We have examined the afferent and efferent projections between the claustrum and visual cortex in the Long-Evans rat using anterograde and retrograde axonal transport techniques. Injections of either wheat germ agglutinin/horseradish peroxidase (WGA/HRP) or Fast Blue were made into each of the main visual regions (17,...

journal_title：Brain research

authors： Carey RG,Neal TL

更新日期：1985-03-11 00:00:00

abstract：:An antagonist to amino acid evoked excitation, gamma-D-glutamylglycine (gamma-DGG) inhibits, dose-dependently, nociceptive C-fibre evoked field potentials and neuronal discharges in single nociceptive neurons in rat spinal cord. It is concluded that amino acids are possible transmitter substance(s) in nociceptive affe...

journal_title：Brain research

authors： Schouenborg J,Sjölund BH

更新日期：1986-08-06 00:00:00

abstract：:The cell-mediated inflammatory component of experimental autoimmune encephalomyelitis (EAE) in mice is measured by the radioisotopic technique. Mice are challenged with autologous spinal cord homogenate in Freund's complete adjuvant and at various time intervals after such immunization given [125I]5-iodo-2'-deoxyuridi...

journal_title：Brain research

authors： Linthicum DS,Horvath L,Carnegie PR

更新日期：1979-10-05 00:00:00

abstract：:Brainstem noradrenergic neurons located in the A5, A6, and A7 catecholamine cell groups provide the entire noradrenergic innervation of the spinal cord. We have previously demonstrated that noradrenergic neurons in the A6 and A7 cell groups innervate the ventral and dorsal horns, respectively. Since the specific spina...

journal_title：Brain research

authors： Clark FM,Proudfit HK

更新日期：1993-07-09 00:00:00

abstract：:The parabrachial nucleus consists of several subnuclei which contains autonomic, gustatory, visceral sensory, nociceptive, and respiratory related neurons. We have investigated the direct projections from the rat parabrachial region, including the K olliker-Fuse nucleus, to the pharyngeal motoneurons with an anterogra...

journal_title：Brain research

authors： Hayakawa T,Zheng JQ,Seki M

更新日期：1999-01-23 00:00:00

abstract：:The following data were obtained from microelectrode exploration of rabbit auditory cortex (AC). (1) Location of AC--Major portions of the rabbit's right hemisphere were stereotaxically mapped for auditory responsive and non-responsive regions. Auditory responsive regions were found to lie behind the rhinal sulcus, ex...

journal_title：Brain research

authors： Kraus N,Disterhoft JF

更新日期：1981-06-15 00:00:00

abstract：:Huntington׳s Disease (HD) is a fatal neurodegenerative disorder caused by expanded polyglutamine repeats in the Huntingtin (HTT) gene. While the gene was identified over two decades ago, it remains poorly understood why mutant HTT (mtHTT) is initially toxic to striatal medium spiny neurons (MSNs). Models of HD using n...

journal_title：Brain research

authors： Mattis VB,Svendsen CN

更新日期：2017-02-01 00:00:00