Abstract:
:Unilateral visual cortex ablations in neonatal rabbits produced no detectable loss of ganglion cells in the contralateral retina following a survival period of 3, 4 or 8 months. Analysis of neuron size distributions and neuron densities from whole-mounted retinas indicate that transneuronal retrograde degeneration does not occur in the rabbit following neonatal visual cortex removal. The results support the hypothesis that axon collaterals play a role in retinal ganglion cell survival in neonatally operated animals. The paradoxical relationship between functional sparing and ganglion cell survival is discussed.
journal_name
Brain Resjournal_title
Brain researchauthors
Wilkes M,Zingaro G,Murphy EHdoi
10.1016/0165-3806(85)90218-4subject
Has Abstractpub_date
1985-08-01 00:00:00pages
293-7issue
2eissn
0006-8993issn
1872-6240journal_volume
353pub_type
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