Survival of the ganglion cell population in the rabbit retina following neonatal visual cortex ablation.

Abstract:

:Unilateral visual cortex ablations in neonatal rabbits produced no detectable loss of ganglion cells in the contralateral retina following a survival period of 3, 4 or 8 months. Analysis of neuron size distributions and neuron densities from whole-mounted retinas indicate that transneuronal retrograde degeneration does not occur in the rabbit following neonatal visual cortex removal. The results support the hypothesis that axon collaterals play a role in retinal ganglion cell survival in neonatally operated animals. The paradoxical relationship between functional sparing and ganglion cell survival is discussed.

journal_name

Brain Res

journal_title

Brain research

authors

Wilkes M,Zingaro G,Murphy EH

doi

10.1016/0165-3806(85)90218-4

subject

Has Abstract

pub_date

1985-08-01 00:00:00

pages

293-7

issue

2

eissn

0006-8993

issn

1872-6240

journal_volume

353

pub_type

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