Maturational changes of amino acid concentration in cerebrospinal fluid of the rat.

abstract：:Several studies have examined the activity of neurons in hypothalamic tissue slices. The present experiments studied relationships between neuronal activity (firing rate and thermosensitivity) and tissue survival as a function of time and slice thickness. Rat hypothalamic tissue slices were sectioned at different thic...

journal_title：Brain research

authors： Burgoon PW,Burry RW,Boulant JA

更新日期：1997-11-28 00:00:00

abstract：:Molecular mechanism underlying ischemic stroke remains poorly understood. We previously reported glucose 6-phosphate dehydrogenase (G6PD) activity in pentose phosphate pathway (PPP) is activated via heat shock protein 27 (HSP27) phosphorylation at serine 85 (S85) by ataxia telangiectasia mutated (ATM) kinase during ce...

journal_title：Brain research

authors： Yamamoto Y,Hosoda K,Imahori T,Tanaka J,Matsuo K,Nakai T,Irino Y,Shinohara M,Sato N,Sasayama T,Tanaka K,Nagashima H,Kohta M,Kohmura E

更新日期：2018-05-15 00:00:00

abstract：:The sexual and associated behaviour of 10 adult male marmosets was recorded during pair tests with ovariectomized females, before and after bilateral thermal lesions of the hypothalamus. Four sham-lesioned males served as controls. Lesions varied in volume from 1.49 to 3.28 mm3 and extended from the ventromedial hypot...

journal_title：Brain research

authors： Lloyd SA,Dixson AF

更新日期：1988-11-01 00:00:00

abstract：:Intrathecal administration of alpha(2) adrenergic agonists, such as clonidine, is capable of alleviating neuropathic pain. Recent studies suggest that spinal nitric oxide (NO) mediates the analgesic effect of intrathecal clonidine. Furthermore, compared to nicotinic receptors, spinal muscarinic receptors play a greate...

journal_title：Brain research

authors： Xu Z,Chen SR,Eisenach J,Pan HL

更新日期：2000-04-10 00:00:00

abstract：:A decline in the magnitude of the summated responses evoked by taste solutions began about 1 h following IXth nerve transection. In 41 IXth nerves transected at different lengths we found a linear relationship between the length of the IXth nerve stump remaining attached to the tongue and the time for the taste respon...

journal_title：Brain research

authors： Oakley B,Jones LB,Hosley MA

更新日期：1980-07-21 00:00:00

abstract：:Examination of the projection from area 2 of the sensory cortex to the motor cortex revealed substantial changes following lesion of the ventrolateral nucleus of the thalamus. These observed changes were as follows. (1) The polarity of the evoked potentials elicited by area 2 stimulation reversed in the depth of the m...

journal_title：Brain research

authors： Asanuma H,Kosar E,Tsukahara N,Robinson H

更新日期：1985-10-14 00:00:00

abstract：:Human truncated tau protein is an active constituent of the neurofibrillary degeneration in sporadic Alzheimer's disease. We have shown that modified tau protein, when expressed as a transgene in rats, induced AD characteristic tau cascade consisting of tau hyperphosphorylation, formation of argyrophilic tangles and s...

journal_title：Brain research

authors： Hrnkova M,Zilka N,Minichova Z,Koson P,Novak M

更新日期：2007-01-26 00:00:00

abstract：:Dopaminergic and glutamatergic afferents simultaneously innervate median spiny neurons (MSNs) and interact to mediate basal ganglia functions. However, the association between dopaminergic and glutamatergic axons is not clear. In the present study, nigrostriatal, corticostriatal, and thalamostriatal axons were anterog...

journal_title：Brain research

authors： Xu C,Zhao J,Liu Y,Zeng X,Jia Y,Wang Y,Jiang X,Xu Q

更新日期：2012-11-27 00:00:00

abstract：:Mild acute hypertension was induced in rats pharmacologically and non-pharmacologically with metaraminol, angiotensin II or bilateral vagotomy. The extraction fraction of water (Ew) was measured in both hypertensive and normotensive animals. It was demonstrated that cerebral blood flow did not change during hypertensi...

journal_title：Brain research

authors： Ling RT,Hartman BK,Clark HB

更新日期：1984-08-13 00:00:00

abstract：:Synaptic membrane (SM) and postsynaptic density (PSD) fractions isolated from the cerebral cortex (CTX) and cerebellum (CL) of the canine brain were found to contain one class of specific nitrendipine binding sites. The specific binding constants were: CTX-SM, Kd = 110 pM (Bmax = 126 fmol/mg protein); CTX-PSD, Kd = 20...

journal_title：Brain research

authors： Wu K,Sachs L,Carlin RK,Siekevitz P

更新日期：1986-11-01 00:00:00

abstract：:Insulin-like 6 immunoreactivity (irINSL6) was detected in Leydig cells of the mouse testis. In the brain, labeled somata were detected mainly in the caudal hypothalamus and midbrain. Double labeling the brainstem sections revealed that irINSL6 somata were 5-hydroxytryptamine (5-HT) positive. The presence of irINSL6 in...

journal_title：Brain research

authors： Brailoiu GC,Dun SL,Yin D,Yang J,Chang JK,Dun NJ

更新日期：2005-04-08 00:00:00

abstract：:An extensive exploration of the discriminating properties of olfactory receptors cells has been conducted in our laboratory through the statistical processing of single cell responses recorded in the frog's olfactory epithelium. Similarities between odorant stimulating properties could be demonstrated by comparing the...

journal_title：Brain research

authors： Sicard G,Holley A

更新日期：1984-02-06 00:00:00

abstract：:Diphtheria toxin (DTX) kills cells by inactivating ribosomal translocation and when used to retrogradely intoxicate cat intercostal motoneurones produces marked morphological alterations in Nissl bodies, including those specifically sited postsynaptic to C-type axon terminals. Here, qualitative examinations of 'intoxi...

journal_title：Brain research

authors： Pullen AH

更新日期：1990-02-12 00:00:00

abstract：BACKGROUND:Diminished dopaminergic neurotransmission contributes to decreased reward and negative eating behaviors in obesity. Bariatric surgery is the most effective therapy for obesity and rapidly reduces hunger and improves satiety through unknown mechanisms. We hypothesized that dopaminergic neurotransmission would...

journal_title：Brain research

authors： Dunn JP,Cowan RL,Volkow ND,Feurer ID,Li R,Williams DB,Kessler RM,Abumrad NN

更新日期：2010-09-02 00:00:00

abstract：:The present study aimed to determine whether the observation of different grasps of the same object elicits automatic imitation of the kinematics of those grasps and this process influences the estimation of intrinsic target properties. In experiments 1 and 2, participants reached and grasped differently sized spheres...

journal_title：Brain research

authors： Gianelli C,Dalla Volta R,Barbieri F,Gentilucci M

更新日期：2008-07-07 00:00:00

abstract：:Compelling evidence from experimental animal disease models and early-phase clinical trials identifies the transplantation of neural progenitor/stem cells (NSCs) as a viable path towards the development of clinically applicable exogenous stem cell therapies. Building from current advances in the field of NSC biology a...

journal_title：Brain research

authors： Willis CM,Nicaise AM,Peruzzotti-Jametti L,Pluchino S

更新日期：2020-02-15 00:00:00

abstract：:The concentration of PGD2, PGE2, and of PGF2 alpha was measured in the cerebrospinal fluid (CSF) collected from the cisterna magna of conscious rats (n = 29), which, chronically implanted with a catheter for the CSF sampling, underwent deprivation of daytime sleep. Significant elevation of the CSF level of PGD2 was ob...

journal_title：Brain research

authors： Ram A,Pandey HP,Matsumura H,Kasahara-Orita K,Nakajima T,Takahata R,Satoh S,Terao A,Hayaishi O

更新日期：1997-03-14 00:00:00

abstract：:The effect of central and peripheral administrations of angiotensin II (AII) on cerebrospinal fluid (CSF) formation was investigated in rabbits anesthetized with intravenous alpha-chloralose and urethane. CSF production was measured by the ventriculo-cisternal perfusion method with Blue dextran 2000 used as an indicat...

journal_title：Brain research

authors： Chodobski A,Szmydynger-Chodobska J,Segal MB,McPherson IA

更新日期：1992-10-23 00:00:00

abstract：:Different doses of angiotensin II (AII) or angiotensin III (AIII) microinjections into the zona incerta have been studied on drinking of rats in separate experiments during the consequent 60-min-daily-drinking period. Also, the dipsogen power of only the effective dose of AII and AIII was compared to vehicle treated r...

journal_title：Brain research

authors： Bagi EE,Fekete E,Lénárd L

更新日期：2003-07-11 00:00:00

abstract：:Anorexia nervosa is associated with vasopressin, oxytocin and serotonin abnormalities. Because of the relationship between exercise and anorexia nervosa, we explored the weight-loss syndrome produced by wheel running in food-deprived rats. Its effects on regional vasopressin and oxytocin concentrations were determined...

journal_title：Brain research

authors： Aravich PF,Rieg TS,Ahmed I,Lauterio TJ

更新日期：1993-05-28 00:00:00

abstract：:Cytochrome P45011B1 (11 beta-hydroxylase) was detected in the brain of male rats by in situ hybridization methods. Normal Sprague-Dawley rats were compared to the transgenic strain TGR(mRen2)27, characterized by the expression of the murine Ren-2d renin gene and the development of severe hypertension. Specific ribopro...

journal_title：Brain research

authors： Erdmann B,Gerst H,Lippoldt A,Bülow H,Ganten D,Fuxe K,Bernhardt R

更新日期：1996-09-09 00:00:00

abstract：:Vasoactive intestinal polypeptide (VIP)-like immunoreactivity in the anterior hypothalamic area (AHA) was studied in 15 bats which are seasonal hibernators, using the unlabeled antibody enzyme method of Sternberger. Our results showed that the density of immunoreactive fibers and terminal plexuses in the AHA was great...

journal_title：Brain research

authors： Laemle LK,Cotter JR

更新日期：1988-02-16 00:00:00

abstract：:The single-unit activity of locus coeruleus noradrenergic (LC-NE) neurons was recorded in freely moving cats during naturally induced defense reactions. Defense reactions, consisting of arched back, piloerection, flattened ears and mydriasis, were elicited by exposing the cat either to a dog, or to a cat displaying ag...

journal_title：Brain research

authors： Levine ES,Litto WJ,Jacobs BL

更新日期：1990-10-29 00:00:00

abstract：:A study of complex I (NADH:ubiquinone oxidoreductase) activity in Parkinson's disease (PD) brain has identified loss of activity only in substantia nigra although loss of activity of this enzyme has been identified in a number of non-brain tissues. We investigated this paradox by studying complex I and other complexes...

journal_title：Brain research

authors： Parker WD Jr,Parks JK,Swerdlow RH

更新日期：2008-01-16 00:00:00

abstract：:Aging represents a major risk factor for numerous illnesses that are of increasing importance to society, including two of the most prevalent: diabetes and Alzheimer's disease. Studies have shown that diabetes is a risk factor for spontaneous Alzheimer's disease. While these studies suggest that diabetes can contribut...

journal_title：Brain research

authors： Oliveira LT,Leon GVO,Provance DW Jr,de Mello FG,Sorenson MM,Salerno VP

更新日期：2015-07-30 00:00:00

abstract：:Headache medicine is primarily dependent on patients' subjective reports of pain, which are assessed at diagnosis and throughout the duration of treatment. There is a need for an objective, quantitative biological measurement of headache pain severity. In this study, quantitative sensory testing (QST) was conducted vi...

journal_title：Brain research

authors： Nguyen RH,Ford S,Calhoun AH,Holden JK,Gracely RH,Tommerdahl M

更新日期：2013-03-01 00:00:00

abstract：:This study was done in urethane anesthetized, ovariectomized (OVX) female rats that were either implanted or not implanted with silastic capsules containing17β-estradiol (E2) to investigate the effect of systemic changes in E2 on the discharge rate of subfornical organ (SFO) neurons that projected to supraoptic nucleu...

journal_title：Brain research

authors： Ciriello J,Roder S

更新日期：2013-08-14 00:00:00

abstract：:Synapsin I is believed to be involved in regulating neurotransmitter release and in synapse formation. Its interactions with the actin filaments and synaptic vesicles are regulated by phosphorylation. Because exocytosis and synapsin I phosphorylation are a Ca(2+)-dependent process, it is possible that an ischemic insu...

journal_title：Brain research

authors： Jung YJ,Park SJ,Park JS,Lee KE

更新日期：2004-01-16 00:00:00

abstract：:Neurons in the polymorph layer of the hippocampal dentate hilus were found to be the cells of origin for ipsilateral association and commissural projections to the dentate gyrus. Both afferent systems terminate in the proximal one-third of the stratum moleculare. The polymorph layer is the primary target for noradrene...

journal_title：Brain research

authors： Berger TW,Semple-Rowland S,Basset JL

更新日期：1981-06-29 00:00:00

abstract：:We utilized proton magnetic resonance spectroscopy to evaluate the metabolic profile of the hippocampus and anterior cingulate cortex of the developing rat brain from postnatal days 14-70. Measured metabolite concentrations were modeled using linear, exponential, or logarithmic functions and the time point at which th...

journal_title：Brain research

authors： Ramu J,Konak T,Liachenko S

更新日期：2016-11-15 00:00:00