Monoclonal antibodies to tyrosine hydroxylase: production and characterization.

Abstract:

:Monoclonal antibodies were produced against tyrosine hydroxylase (TH), the enzyme catalyzing the rate limiting step in catecholamine neurotransmitter synthesis. An enzyme linked immunosorbant assay was used to detect the presence of specific antibody in culture. Specificity of the antibodies is characterized. These monospecific antibodies were used for immunoprecipitation and immunohistochemical staining of TH in brain.

journal_name

Brain Res

journal_title

Brain research

authors

Ross ME,Reis DJ,Joh TH

doi

10.1016/0006-8993(81)90583-7

subject

Has Abstract

pub_date

1981-03-16 00:00:00

pages

493-8

issue

2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(81)90583-7

journal_volume

208

pub_type

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