Abstract:
:Distribution of prolactin-releasing peptide-like immunoreactivity (PrRP-LI) was investigated in the rat medulla with the use of a rabbit polyclonal antiserum against the human PrRP-31 peptide. PrRP-positive neurons were noted mainly in two areas of the caudal medulla: ventrolateral reticular formation and commissural nucleus of the nucleus of the solitary tract (NTS), corresponding to the A1 and A2 areas. PrRP-LI neurons were absent in the medulla rostral to the area postrema. Double-labeling the sections with PrRP antisera and tyrosine hydroxylase (TH) monoclonal antibodies revealed extensive colocalization of PrRP- and TH-like immunoreactivity (TH-LI) in neurons of the A1 and A2 areas. Our results show that PrRP-LI is expressed in a population of A1 and A2 noradrenergic neurons of the rat caudal medulla.
journal_name
Brain Resjournal_title
Brain researchauthors
Chen C,Dun SL,Dun NJ,Chang JKdoi
10.1016/s0006-8993(99)01153-1subject
Has Abstractpub_date
1999-03-20 00:00:00pages
276-9issue
1-2eissn
0006-8993issn
1872-6240pii
S0006-8993(99)01153-1journal_volume
822pub_type
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