Excitatory amino acid receptor regulation after subthalamic nucleus lesions in the rat.

abstract：:We developed a new model of embolic cerebral ischemia in the rat which provides a reproducible and predictable infarct volume within the territory supplied by the middle cerebral artery (MCA). The MCA was occluded by an embolus in Wistar rats (n = 71). An additional three non-embolized rats were used as a control. Cer...

journal_title：Brain research

authors： Zhang RL,Chopp M,Zhang ZG,Jiang Q,Ewing JR

更新日期：1997-08-22 00:00:00

abstract：:Altered dopamine regulation in the medial prefrontal cortex has been linked to drug abuse and disorders such as schizophrenia. Heterogeneous expression of the dopamine transporter, as well as the ability of the norepinephrine transporter to clear dopamine in the prefrontal cortex, delineates two potential sites for th...

journal_title：Brain research

authors： Mazei MS,Pluto CP,Kirkbride B,Pehek EA

更新日期：2002-05-17 00:00:00

abstract：:More than 50% of the Xenopus pectoralis twitch muscle fibers with two distant endplates are innervated at both sites by the same neuron. This study indicates that there are three separable twitch motor unit types in this muscle which show very little overlap in innervation. This study also shows that each motor unit i...

journal_title：Brain research

authors： Nudell B,Grinnell AD

更新日期：1985-03-25 00:00:00

abstract：:Recent studies have shown that moving in synchrony with auditory stimuli boosts attention allocation and verbal learning. Furthermore rhythmic tones are processed more efficiently than temporally random tones ('timing effect'), and this effect is increased when participants actively synchronize their motor performance...

journal_title：Brain research

authors： Schmidt-Kassow M,Thöne K,Kaiser J

更新日期：2019-08-01 00:00:00

abstract：:The dentato-olivary projection has been ultrastructurally studied in rats that received a wheatgerm agglutinin-horseradish peroxidase (WGA-HRP) injection in the nucleus lateralis. Ultrathin sections containing the inferior olive have been double-labelled with the GABA-immunogold method. About 97% of the WGA-HRP labell...

journal_title：Brain research

authors： Angaut P,Sotelo C

更新日期：1989-02-13 00:00:00

abstract：:Bromodeoxyuridine (BrUdR) injected into Xenopus embryos at stages before, during or after the last period of DNA synthesis in Mauthner's neurons had no serious effect on differentiation of Mauthner's neurons. However, the BrUdR caused widespread cell degeneration in the central nervous system. The action of BrUdR on r...

journal_title：Brain research

authors： Dribin LB,Jacobson M

更新日期：1978-07-21 00:00:00

abstract：:Alterations in local cerebral glucose utilization (LCGU) induced by electrical stimulation of the sensory relay nucleus (VPL) or parafascicular nucleus (Pf) of the thalamus in conscious rats were measured by the [14C]2-deoxyglucose method, the objective being to assess the mechanism of analgesia induced by electrical ...

journal_title：Brain research

authors： Aiko Y,Shima F,Hosokawa S,Kato M,Kitamura K

更新日期：1987-04-07 00:00:00

abstract：:Repeated administration of high doses of methamphetamine produced long-term decreases in dopamine (DA) levels and in the number of DA uptake sites in the rat striatum. These two effects were dose-related and did not appear to be due to the continued presence of drug in striatal tissue. Long-lasting depletions induced ...

journal_title：Brain research

authors： Wagner GC,Ricaurte GA,Seiden LS,Schuster CR,Miller RJ,Westley J

更新日期：1980-01-06 00:00:00

abstract：:Previous work has shown that administration of corticotropin-releasing factor (CRF) into the lateral ventricle antagonizes the orexigenic effect of neuropeptide Y (NPY), and central injection of CRF antagonist, alpha-helical CRF(9-41) enhanced NPY-induced food intake in satiated rats. The aim of the present study was ...

journal_title：Brain research

authors： Menzaghi F,Heinrichs SC,Pich EM,Tilders FJ,Koob GF

更新日期：1993-07-30 00:00:00

abstract：:Programmed cell death has been implicated in the loss of neurons that occurs in many neurodegenerative diseases. This has led to an increased interest in the types of stimuli that can initiate neurons to undergo programmed cell death. Previously, we have shown that cross-linking of membrane receptors with the lectin c...

journal_title：Brain research

authors： Azizeh BY,Cribbs DH,Kreng VM,Cotman CW

更新日期：1998-06-15 00:00:00

abstract：:Light microscopic double labeling immunocytochemistry for vasoactive intestinal peptide (VIP) and gonadotrophin-releasing hormone (GnRH) was carried out on the hypothalami of male and female rats. It was found that the number of VIP boutons that terminate on GnRH neurons and the percentage of GnRH neurons contacted by...

journal_title：Brain research

authors： Horvath TL,Cela V,van der Beek EM

更新日期：1998-06-08 00:00:00

abstract：:Dipiperidinoethane (DPE) administration produces seizures and CNS lesions. Here we elucidate the cholinergic origin of DPE toxicity. DPE is both an acetylcholinesterase (AChE) inhibitor and a muscarinic antagonist. This dual action negates most of the toxic effects of the compound in vivo. The neurotoxicity is believe...

journal_title：Brain research

authors： Baron BM,Kashman Y,Sokolovsky M

更新日期：1985-04-01 00:00:00

abstract：:The amygdala has long been implicated in conditioned fear. The mesencephalic dopaminergic system provides a rich innervation to the amygdala [J.H. Fallon, P. Ciofi, Distribution of monoamines within the amygdala, in: J.P. Aggleton (Ed.), The Amygdala: Neurobiological Aspects of Emotion, Memory and Mental Dysfunction, ...

journal_title：Brain research

authors： Guarraci FA,Frohardt RJ,Kapp BS

更新日期：1999-05-08 00:00:00

abstract：:The known neurochemical effect of most currently available antidepressants is the enhancement of the synaptic levels of monoamine neurotransmitters. However, the existence of other mechanisms has been suggested to justify the significant delay between the modulation of the monoaminergic system and the clinical effects...

journal_title：Brain research

authors： Cecconi D,Mion S,Astner H,Domenici E,Righetti PG,Carboni L

更新日期：2007-03-02 00:00:00

abstract：:Previous studies have found that the primary change in the brain of chronic alcoholics is a selective loss of white matter in cerebral hemispheres. It is unknown whether the loss of white matter is due to alcohol-induced degeneration of axons in white matter, and this hypothesis has never been tested. We used a newly ...

journal_title：Brain research

authors： Tang Y,Pakkenberg B,Nyengaard JR

更新日期：2004-12-17 00:00:00

abstract：:Previous studies have shown that one of the genetic variants BDNF val66met polymorphism is associated with drug addiction. Age at onset for drugs abuse has also been regularly cited as a factor associated with high genetic predispositions. We conducted an exploratory research to investigate the association of BDNF val...

journal_title：Brain research

authors： Hou H,Qing Z,Jia S,Zhang X,Hu S,Hu J

更新日期：2010-09-24 00:00:00

abstract：:Tyrosine hydroxylase phenotype expression was investigated in the catecholaminergic population of the locus coeruleus neurons of two pure inbred mouse strains, Balb/C and C57Black/6. Therefore, we have characterized the precise organization of tyrosine hydroxylase-expressing perikarya population, in control animals an...

journal_title：Brain research

authors： Ginovart N,Marcel D,Bezin L,Garcia C,Gagne C,Pujol JF,Weissmann D

更新日期：1996-05-20 00:00:00

abstract：:The entire set of giant interneurons (GIs) in the nerve cord of the cockroach, Periplaneta americana, was ablated using either electrolytic or surgical techniques. All animals with these lesions were capable of turning and running away from standard wind puffs. However, all animals responded much less frequently to st...

journal_title：Brain research

authors： Comer CM,Dowd JP,Stubblefield GT

更新日期：1988-04-05 00:00:00

abstract：:Adiponectin (APN), a circulating adipose-derived hormone regulating inflammation and energy metabolism, has beneficial actions on cardio- and cerebrovascular disorders. Hypoadiponectinemia is associated with ischemic cerebrovascular disease, however, little is known about the cerebroprotective action of APN as well as...

journal_title：Brain research

authors： Chen B,Liao WQ,Xu N,Xu H,Wen JY,Yu CA,Liu XY,Li CL,Zhao SM,Campbell W

更新日期：2009-06-01 00:00:00

abstract：:We examined the effects of systemic administration of gamma-vinyl gamma-aminobutyric acid (GVG), a gamma-aminobutyric acid (GABA) transaminase inhibitor, on the kindling model of epilepsy in rats. GVG (1200 or 1500 mg/kg) approximately doubled the number of stimulations required for kindling development. GVG also supp...

journal_title：Brain research

authors： Shin C,Rigsbee LC,McNamara JO

更新日期：1986-11-29 00:00:00

abstract：:In order to examine the relationship between myelination and sensitivity to anoxia in adult white matter, we studied action potential conduction in the spinal cord dorsal column of adult rats in which focal demyelinating lesions had been produced using ethidium bromide/X-irradiation. Acutely isolated spinal cords from...

journal_title：Brain research

authors： Imaizumi T,Kocsis JD,Waxman SG

更新日期：1998-01-01 00:00:00

abstract：:Granule cell progenitors in the dentate gyrus of the hippocampal formation have the unusual capacity to be able to divide in the brains of adult rats and primates. The basal proliferation rate of granule cell progenitors in the adult rat is low compared with development, however, it is possible that this rate may beco...

journal_title：Brain research

authors： Gray WP,Sundstrom LE

更新日期：1998-04-20 00:00:00

abstract：:The involvement of striatal cholinergic neurons in the release of dopamine (DA) elicited by the mu-opioid receptor agonist DAGO ([D-Ala2, NMePhe4-Gly5(ol)]enkephalin) was explored. The striatal release of DA was measured by microdialysis in rats anesthetized with chloral hydrate. When infused in the striatum, through ...

journal_title：Brain research

authors： Dourmap N,Clero E,Costentin J

更新日期：1997-02-28 00:00:00

abstract：:Using the teased fiber recording method, we have compared pathophysiological properties of afferent axons injured in the infraorbital nerve (ION) vs the sciatic nerve in rats. Both myelinated and unmyelinated axons ending in ION neuromas produced much less ongoing discharge than those ending in sciatic nerve neuromas....

journal_title：Brain research

authors： Tal M,Devor M

更新日期：1992-05-01 00:00:00

abstract：:Sera from patients with multiple sclerosis (MS) frequently produce demyelination of central nervous system tissue cultures. The nature of the factors responsible for demyelination is not as yet clearly established. However, several authors previously reported, in in vivo and in vitro models, demyelinating activity in ...

journal_title：Brain research

authors： Grundke-Iqbal I,Bornstein MB

更新日期：1979-01-19 00:00:00

abstract：:In anesthetized, artificially ventilated cats, pretreated with the muscarinic antagonist scopolamine, the effect of naloxone on the efficacy of nicotinic transmission in the superior cervical ganglion was used as a test of endogenous opioid release by the preganglionic axons. The cervical sympathetic trunk (CST) was s...

journal_title：Brain research

authors： Zhang C,Bachoo M,Polosa C

更新日期：1991-05-10 00:00:00

abstract：:Evidence is presented which suggests that central neural changes occur during the brief early phase after subcutaneous formalin injection that are essential for the expression of pain during the long-lasting (tonic) later phase. First, tonic pain responses to subcutaneous formalin injections are abolished only if the ...

journal_title：Brain research

authors： Coderre TJ,Vaccarino AL,Melzack R

更新日期：1990-12-03 00:00:00

abstract：:Neuronal expression of brain-derived neurotrophic factor (BDNF) has been implicated in the mechanism of infarct tolerance (resistance to stroke) (H. Yanamoto et al., Infarct tolerance accompanied enhanced BDNF-like immunoreactivity in neuronal nuclei, submitted to Brain Res.), a process that takes more than 7 days fol...

journal_title：Brain research

authors： Yanamoto H,Nagata I,Sakata M,Zhang Z,Tohnai N,Sakai H,Kikuchi H

更新日期：2000-03-24 00:00:00

abstract：:Entopeduncular nucleus (EPN) cells which project to thalamic and non-thalamic sites were identified by antidromic discharge. Each population of cells, projecting to the ventral anterior nucleus of the thalamus (VA), centrum medianum (CM), the lateral habenula (LHB), and the pedunculopontine nucleus (PP), was distribut...

journal_title：Brain research

authors： Larsen KD,Sutin J

更新日期：1978-11-17 00:00:00

abstract：:Reduced neuronal plasticity in the striatum, hippocampus, and neocortex is a common feature of transgenic mouse models of Huntington's disease (HD). Doublecortin (DCX) and polysialylated neural cell adhesion molecule (PSA-NCAM) are associated with structural plasticity in the adult mammalian brain, are markers of newl...

journal_title：Brain research

authors： Lazic SE,Goodman AO,Grote HE,Blakemore C,Morton AJ,Hannan AJ,van Dellen A,Barker RA

更新日期：2007-06-02 00:00:00