Altered local cerebral glucose utilization induced by electrical stimulations of the thalamic sensory and parafascicular nuclei in rats.

abstract：:The growth inhibitory factor (GIF) is a new metallothionein (MT)-like protein that is downregulated in Alzheimer's disease (AD) brain. The biological function of GIF has not been fully clarified yet. We have raised an antibody to the synthetic polypeptide that is specific for rat GIF. The purified antibody reacted to ...

journal_title：Brain research

authors： Hozumi I,Inuzuka T,Hiraiwa M,Uchida Y,Anezaki T,Ishiguro H,Kobayashi H,Uda Y,Miyatake T,Tsuji S

更新日期：1995-08-07 00:00:00

abstract：:Long-term exposure to different antidepressant treatments induces increased motor response to central stimulants, due to a selective supersensitivity of dopamine D2 receptors in the limbic areas. Such an effect is accompanied by down-regulation of dopamine D1 receptor number, and by a decreased response of adenylyl cy...

journal_title：Brain research

authors： De Montis MG,Gambarana C,Meloni D,Taddei I,Tagliamonte A

更新日期：1993-03-19 00:00:00

abstract：:The divalent cation zinc has been reported to possess several physiological properties such as blocking apoptotic cell death through an inhibitory effect on Ca(2+)-Mg2+ endonuclease activity, or modulating the neurotoxicity via glutamate receptor subtypes. In the present study, we investigated the effect of peripheral...

journal_title：Brain research

authors： Matsushita K,Kitagawa K,Matsuyama T,Ohtsuki T,Taguchi A,Mandai K,Mabuchi T,Yagita Y,Yanagihara T,Matsumoto M

更新日期：1996-12-16 00:00:00

abstract：:The intercollicular pathway of the rat was studied using autoradiographic (ARG) and horseradish peroxidase (HRP) tracing techniques. The HRP experiments demonstrated that the cells of origin of the intertectal pathway were located primarily in the rostral stratum griseum intermediale ( SGI ), stratum album intermedium...

journal_title：Brain research

authors： Yamasaki DS,Krauthamer G,Rhoades RW

更新日期：1984-05-23 00:00:00

abstract：:D-Fen-induced hyperthermia has been shown to coincide with an enhanced depletion of 5-HT and 5-hydroxyindole acetic acid (5-HIAA). Because these observations have relied on D-Fen exposure at multiple environmental temperatures, some have questioned the validity of the findings. Therefore, this experiment was designed ...

journal_title：Brain research

authors： Stewart CW,Slikker W Jr

更新日期：1999-08-28 00:00:00

abstract：:We have examined the soma diameters and distribution of catecholaminergic (CA) cells in human retinae, by using an antibody to tyrosine hydroxylase (TH), the rate limiting enzyme in the production of catecholamines. TH-immunoreactivity was detected in two classes of cells (CA1 and CA2 cells). CA1 cells had relatively ...

journal_title：Brain research

authors： Mitrofanis J,Provis JM

更新日期：1990-09-10 00:00:00

abstract：:Neurotensin (NT) is an endogenous brain tridecapeptide for which high affinity binding sites exist in the central nervous system. We have investigated the effects of NT incubation with rat neostriatal slices on calcium/calmodulin (Ca/CaM)-dependent protein phosphorylation. Slices were incubated with NT (5 or 50 nM) fo...

journal_title：Brain research

authors： Kasckow J,Cain ST,Nemeroff CB

更新日期：1991-04-05 00:00:00

abstract：:[3H]Quinuclidinyl benzilate (QNB), [3H]lysergic acid diethylamide (LSD) and [3H]pyrilamine were used with radiohistochemistry to determine the distribution of muscarinic, serotonergic and histaminergic binding sites, respectively, in cat spinal cord. Each ligand displayed a unique pattern of binding sites in the super...

journal_title：Brain research

authors： Seybold VS

更新日期：1985-09-09 00:00:00

abstract：:Axotomy of cholinergic neurons in the medial septum-diagonal band and degeneration of their terminals in the hippocampus resulting from fornix-fimbria lesions induce elevation of NGF content in these two brain regions. Postlesion levels of cholinergic neuron-specific ChAT activity in the septum suggest that endogenous...

journal_title：Brain research

authors： Gasser UE,Weskamp G,Otten U,Dravid AR

更新日期：1986-06-25 00:00:00

abstract：:Male Long-Evans rats were administered nicotine bitartrate or sodium tartrate either during adolescence (p29-43) or adulthood (p80-94). Route of administration was via subcutaneously implanted osmotic pump (initial dose 2.0 mg/kg/day, free base). Five weeks following nicotine administration, brains were processed for ...

journal_title：Brain research

authors： McDonald CG,Eppolito AK,Brielmaier JM,Smith LN,Bergstrom HC,Lawhead MR,Smith RF

更新日期：2007-06-02 00:00:00

abstract：:The connectivity of the stellate ganglion of Octopus was investigated using cobalt and horseradish peroxidase (HRP) tracers applied to severed preganglionic and postganglionic nerves. Centripetal cells, defined as cells in the ganglion which send their axons back toward the brain, were discovered by both methods. Appl...

journal_title：Brain research

authors： Monsell EM

更新日期：1980-02-17 00:00:00

abstract：:The ionic basis of norepinephrine (NE) action was studied with intracellular recording techniques in the rat hippocampal slice. Topical application of NE caused, in CA1 neurons, a 3-4 mV hyperpolarization associated with a 10-20% decrease in input resistance. This effect was accompanied by a decrease in spontaneous ac...

journal_title：Brain research

authors： Segal M

更新日期：1981-02-09 00:00:00

abstract：:Adult Long-Evans female rats sustained electrolytic fimbria-fornix lesions and, two weeks later, received intrahippocampal suspension grafts of fetal septal tissue. Sham-operated and lesion-only rats served as controls. Between 6.5 and 8 months after grafting, both the [3H]choline accumulation and the electrically evo...

journal_title：Brain research

authors： Cassel JC,Jeltsch H,Neufang B,Lauth D,Szabo B,Jackisch R

更新日期：1995-12-18 00:00:00

abstract：:Axon-to-myelin transfer of lipids precursors have been studied in the rabbit optic system by intraocular injection of [32P]orthophosphate, [14C]glycerol and [3H]glycerol. Choline and ethanolamine phosphoglycerides and myelin showed increasing [32P]-radioactivity between 7 and 21 days following injection, while [3H]- a...

journal_title：Brain research

authors： Ledeen RW,Haley JE

更新日期：1983-06-20 00:00:00

abstract：:The central nervous system (CNS) in adult mammals loses the ability to regenerate after injury. Although electrical stimulation (ES) has been shown to promote neural regeneration, the underlying mechanisms by which ES enhances CNS regeneration remain elusive. The aim of the present study was to investigate the effect ...

journal_title：Brain research

authors： Ou YT,Lu MS,Chiao CC

更新日期：2012-10-22 00:00:00

abstract：:It has been well established that the mitochondrial ATP-sensitive potassium channel (mitoK(ATP)) opener, diazoxide, has protective effects on the heart and brain following ischemia/reperfusion injury. However, the mechanism of the neuroprotective effects of diazoxide remains unclear. This study highlights the anti-apo...

journal_title：Brain research

authors： Zhang H,Wang ZQ,Zhao DY,Zheng DM,Feng J,Song LC,Luo Y

更新日期：2011-01-25 00:00:00

abstract：:In the present study we investigated the correlation between radiation-induced metabolic and histopathological changes in the brain under experimental conditions. Adult male Wistar rats received fractionated whole-brain irradiation (fWBI) with a total dose of 40 Gy administered in 5 fractions (dose 8 Gy per fraction) ...

journal_title：Brain research

authors： Bálentová S,Hnilicová P,Kalenská D,Baranovičová E,Muríň P,Bittšanský M,Hajtmanová E,Lehotský J,Adamkov M

更新日期：2019-04-01 00:00:00

abstract：:A transplantable mouse testicular teratoma (OTT 6050) which displays a spectrum of neuroepithelial differentiation was evaluated biochemically for concentrations of cyclic AMP (cAMP), serotonin (5-HT), and enzymes involved in the metabolism of the biogenic amines and acetylcholine. These values were compared between t...

journal_title：Brain research

authors： Orenberg EK,Vandenberg SR,Barchas JD,Herman MM

更新日期：1976-01-16 00:00:00

abstract：:The suprachiasmatic nucleus (SCN) and the pineal body in 3 types of inherited hormone-deficient mice, the dw, lit and hyt mice were examined by morphological, morphometric and biochemical techniques. In the dw and lit mice the SCN was underdeveloped. In the ventral part of the SCN, where most of the retinal fibers app...

journal_title：Brain research

authors： Noguchi T,Sugisaki T,Kudo M,Satoh I

更新日期：1986-05-01 00:00:00

abstract：:Repeated intermittent administration of amphetamines acutely increases appetitive and consummatory aspects of motivated behaviors as well as general activity and exploratory behavior, including voluntary running wheel activity. Subsequently, if the drug is withdrawn, the frequency of these behaviors decreases, which i...

journal_title：Brain research

authors： Kitanaka N,Kitanaka J,Hall FS,Uhl GR,Watabe K,Kubo H,Takahashi H,Tatsuta T,Morita Y,Takemura M

更新日期：2012-01-06 00:00:00

abstract：:The present study focuses on the myelination of rat septohippocampal fibres that are known to originate from GABAergic parvalbumin-containing, fast-firing, fast-conducting neurons and from cholinergic slow-firing, slow-conducting neurons. With the combined immunofluorescence for parvalbumin/myelin basic protein and ch...

journal_title：Brain research

authors： Brauer K,Härtig W,Gärtner U,Brückner G,Arendt T

更新日期：2000-09-29 00:00:00

abstract：:Impaired learning has been shown as a consequence of isolation-rearing in a variety of paradigms. However, there are situations in which learning in isolation-reared rats is enhanced or unimpaired compared to socially reared rats. The present experiments investigated the effects of isolation rearing on place navigatio...

journal_title：Brain research

authors： Wongwitdecha N,Marsden CA

更新日期：1996-04-09 00:00:00

abstract：:Extracellular recordings were obtained from spontaneously active neurones located in the dorsal motor nucleus of vagus nerve ( DMX ) in slices of the rat brainstem. Oxytocin applied to the bath at concentrations of 10(-7) M or 10(-6) M excited 79% of these cells in a concentration-dependent, reversible manner. The rem...

journal_title：Brain research

authors： Charpak S,Armstrong WE,Mühlethaler M,Dreifuss JJ

更新日期：1984-05-21 00:00:00

abstract：:Biochemical analysis of the binding of [125I]Bolton-Hunter coupled substance P [( 125I]BH-SP) to slide-mounted sections of rat brain demonstrated that [125I]BH-SP labels a binding site with a structure-activity profile characteristic of a substance P receptor. Under optimized preincubation and incubation conditions, t...

journal_title：Brain research

authors： Rothman RB,Herkenham M,Pert CB,Liang T,Cascieri MA

更新日期：1984-08-20 00:00:00

abstract：:GPR56, a member of the G-protein-coupled receptor family, plays a role in the formation of the frontal and parietal brain lobes and cortical lamination in the embryonic stage. A recent report indicated the existence of GPR56 transcripts in the subventricular zone (SVZ) and hippocampal subgranular zone (SGZ) of the adu...

journal_title：Brain research

authors： Suzuki G,Kanda Y,Nibuya M,Hiramoto T,Tanaka T,Shimizu K,Watanabe Y,Nomura S

更新日期：2007-12-05 00:00:00

abstract：:There exists evidence to support the notion that the segmental reflex system is not fixed and inflexible, but rather is highly modifiable under a variety of circumstances. In this study the H-wave and M-wave recruitment curves were obtained from 19 subjects, utilizing the procedures outlined by Hugon. Each subject was...

journal_title：Brain research

authors： Koceja DM,Trimble MH,Earles DR

更新日期：1993-11-26 00:00:00

abstract：:The cholinergic innervation of the mediodorsal (MD) nucleus of the thalamus was visualized immunohistochemically in human brain postmortem, using an antibody against human choline acetyltransferase (ChAT). The ChAT staining of the MD nucleus was more intense than in the surrounding thalamic nuclei but weaker than that...

journal_title：Brain research

authors： Brandel JP,Hirsch EC,Hersh LB,Javoy-Agid F

更新日期：1990-05-07 00:00:00

abstract：:The anatomical distribution of L-[3H]glutamate binding sites was determined in the presence of various glutamate analogues using quantitative autoradiography. The binding of L-[3H]glutamate is accounted for by the presence of 3 distinct binding sites when measured in the absence of Ca2+, Cl- and Na+ ions. The anatomic...

journal_title：Brain research

authors： Monaghan DT,Yao D,Cotman CW

更新日期：1985-08-12 00:00:00

abstract：:The involvement of striatal cholinergic neurons in the release of dopamine (DA) elicited by the mu-opioid receptor agonist DAGO ([D-Ala2, NMePhe4-Gly5(ol)]enkephalin) was explored. The striatal release of DA was measured by microdialysis in rats anesthetized with chloral hydrate. When infused in the striatum, through ...

journal_title：Brain research

authors： Dourmap N,Clero E,Costentin J

更新日期：1997-02-28 00:00:00

abstract：:The effect of electrolytic lesion of the paraventricular nucleus of the hypothalamus (PVN) on yawning and penile erection induced by apomorphine, oxytocin and adrenocorticotropic hormone (ACTH1-24) was studied in male rats. In sham-operated rats, apomorphine (50 micrograms/kg s.c.), oxytocin (30 ng i.c.v.), and ACTH1-...

journal_title：Brain research

authors： Argiolas A,Melis MR,Mauri A,Gessa GL

更新日期：1987-09-22 00:00:00