Increased number of galanin-neurons in the paraventricular hypothalamic nucleus of neonatally overfed weanling rats.

Abstract:

:Perinatal overfeeding is a risk factor for overweight and diabetes during life. Underlying pathophysiological mechanisms are unclear. The peptide galanin is suggested to stimulate food intake by acting within the paraventricular hypothalamic nucleus (PVN). In early postnatally overfed rats overweight and hyperinsulinemia were observed, accompanied by an increased number of galanin-positive neurons in the PVN at weaning. Our results might indicate malformation of hypothalamic galaninergic neurons due to neonatal overfeeding and hyperinsulinism, respectively, in rats.

journal_name

Brain Res

journal_title

Brain research

authors

Plagemann A,Harder T,Rake A,Melchior K,Rohde W,Dörner G

doi

10.1016/s0006-8993(98)01264-5

subject

Has Abstract

pub_date

1999-02-06 00:00:00

pages

160-3

issue

1

eissn

0006-8993

issn

1872-6240

pii

S0006-8993(98)01264-5

journal_volume

818

pub_type

杂志文章
  • Conditional immortalization of neuronal cells from postmitotic cultures and adult CNS.

    abstract::To determine whether postmitotic neurons can be immortalized by oncogenic transduction, we used two approaches involving conditional expression of a temperature-sensitive SV40 large T antigen (Tts). Initially, Tts was introduced into E17 rat embryonal hippocampal cells that were then cultured at the non-permissive tem...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(94)91484-2

    authors: Eves EM,Kwon J,Downen M,Tucker MS,Wainer BH,Rosner MR

    更新日期:1994-09-12 00:00:00

  • Dynamic cerebral autoregulation and baroreflex sensitivity during modest and severe step changes in arterial PCO2.

    abstract::Changes in the partial pressure of arterial CO2 (PaCO2) regulates cerebrovascular tone and dynamic cerebral autoregulation (CA). Elevations in PaCO2 also increases autonomic neural activity and may alter the arterial baroreflex. We hypothesized that hypercapnia would impair, and hypocapnia would improve, dynamic CA an...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2008.07.048

    authors: Ainslie PN,Celi L,McGrattan K,Peebles K,Ogoh S

    更新日期:2008-09-16 00:00:00

  • Activation of central mu-opioid receptors is involved in clonidine analgesia in rats.

    abstract::The analgesic effect of clonidine in spontaneously hypertensive rats (SHR) and in normotensive Sprague-Dawley (SD) rats was assessed by using the formalin pain test. The analgesic response of SD rats to low doses (15-60 micrograms/kg i.p.) but not to a high dose (150 micrograms/kg i.p.) of clonidine was inhibited by n...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(89)91630-2

    authors: Mastrianni JA,Abbott FV,Kunos G

    更新日期:1989-02-13 00:00:00

  • Physical aggression and attentional bias to angry faces: An event related potential study.

    abstract::This study aimed to identify the neural correlates of aggression-related attentional selectivity to angry faces in physical aggression. Physical aggression in a non-clinical sample of young men (N = 36) was measured using an aggression questionnaire. Visual attentional bias to angry faces was assessed using a dot-prob...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2019.146387

    authors: Crago RV,Renoult L,Biggart L,Nobes G,Satmarean T,Bowler JO

    更新日期:2019-11-15 00:00:00

  • Spinal and trigeminal lamina I input to the locus coeruleus anterogradely labeled with Phaseolus vulgaris leucoagglutinin (PHA-L) in the cat and the monkey.

    abstract::Terminal fibers anterogradely labeled with Phaseolus vulgaris leucoagglutinin (PHA-L) were observed in the locus coeruleus in the brainstem of the cat and the cynomolgus monkey following injections in lamina I of the spinal or medullary dorsal horn. Thus, thermoreceptive- or nociceptive-specific lamina I cells that pr...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(92)90915-v

    authors: Craig AD

    更新日期:1992-07-03 00:00:00

  • Origin of descending afferents to the rostral part of dorsal cap of inferior olive which transfers contralateral optic activities to the flocculus. A horseradish peroxidase study.

    abstract::Neurons in the ventromedial tegmental area that project to the rostral part of the dorsal cap of the ipsilateral inferior olive were labeled by the technique of retrograde transport of horseradish peroxidase (HRP). Following iontophoresis of HRP into the rostral part of the dorsal cap a cluster of labeled cells are fo...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(79)90574-2

    authors: Maekawa K,Takeda T

    更新日期:1979-08-31 00:00:00

  • Distribution of somatostatin in the brain and of somatostatin and thyrotropin-releasing hormone in peripheral tissues of the chicken.

    abstract::Our research group recently presented the distribution of thyrotropin-releasing hormone (TRH) in the chicken brain. In this study we measured somatostatin (SRIH) concentrations in different brain parts and nuclei. The distribution of SRIH and TRH in peripheral tissues was also studied. Although the highest SRIH conten...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(00)02550-6

    authors: Geris KL,Meeussen G,Kühn ER,Darras VM

    更新日期:2000-08-11 00:00:00

  • 31P NMR phospholipid characterization of intracranial tumors.

    abstract::Phospholipid extracts from 48 intracranial tumors were analyzed using 31P NMR. Phospholipids commonly identified in the tumor spectra included phosphatidylglycerol (PG), phosphatidic acid (PA), diphosphatidylglycerol (DPG), uncharacterized phospholipid (U), ethanolamine plasmalogen (EPLAS), phosphatidylethanolamine (P...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(94)91041-3

    authors: Merchant TE,van der Ven LT,Minsky BD,Diamantis PM,Delapaz R,Galicich J,Glonek T

    更新日期:1994-06-27 00:00:00

  • Elevated TRH levels in pyriform cortex after partial and fully generalized kindled seizures.

    abstract::In a previous study we reported significant elevations of TRH in neocortex, hippocampus and combined amygdala/pyriform cortex in rats 48 h after the last of a series of stage 5 kindled seizures. In the present study, to determine whether the increases in TRH were proportional to the intensity of the convulsions, and t...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(90)91330-j

    authors: Meyerhoff JL,Bates VE,Kubek MJ

    更新日期:1990-08-13 00:00:00

  • Cardiorespiratory fitness and brain diffusion tensor imaging in adults over 80 years of age.

    abstract::A positive association between cardiorespiratory fitness (CRF) and white matter integrity has been consistently reported in older adults. However, it is unknown whether this association exists in adults over 80 with a range of chronic disease conditions and low physical activity participation, which can influence both...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2014.09.003

    authors: Tian Q,Simonsick EM,Erickson KI,Aizenstein HJ,Glynn NW,Boudreau RM,Newman AB,Kritchevsky SB,Yaffe K,Harris T,Rosano C,Health ABC study.

    更新日期:2014-11-07 00:00:00

  • Evidence that L-type calcium channels do not contribute to static vestibular function in the guinea pig vestibular nucleus.

    abstract::Labyrinthine-intact guinea pigs received unilateral, brainstem cannula injections of (1) 2.5 micrograms of the selective dihydropyridine L-type Ca2+ channel agonist, Bay K 8644 (n = 4 animals); (2) 10 micrograms Bay K 8644 (n = 4); 12.5 micrograms of the selective dihydropyridine L-type Ca2+ channel antagonist, nifedi...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(93)90677-f

    authors: Sansom AJ,Smith PF,Darlington CL

    更新日期:1993-12-10 00:00:00

  • Analgesic synergy and improved motor function produced by combinations of mu-delta- and mu-kappa-opioids.

    abstract::This study evaluated the effects of intrathecal administration of a low-analgesic dose of the selective mu-agonist DAMGO co-administered with sequentially increasing doses of either the selective delta-agonist DPDPE or the selective kappa-agonist, U50,488H on mechanical nociceptive thresholds in the rat. Potent analge...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(90)91297-t

    authors: Sutters KA,Miaskowski C,Taiwo YO,Levine JD

    更新日期:1990-10-22 00:00:00

  • Fine structure of GABAergic neurons and synapses in the human dentate gyrus.

    abstract::Surgical tissue samples of the human dentate gyrus were immunostained for glutamate decarboxylase (GAD), the gamma-aminobutyric acid (GABA)-synthesizing enzyme, and studied by both light and electron microscopy. Immunoreactive neurons and terminals displayed similar morphological characteristics as known from studies ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(87)91181-4

    authors: Schlander M,Thomalske G,Frotscher M

    更新日期:1987-01-13 00:00:00

  • Histaminergic modulation of acoustically induced running behavior in rats.

    abstract::Explosive running is a reliable initial component of audiogenic seizures (AS) induced by acoustic stimulation in genetically prone rodents. This profound locomotor activation is usually considered as a convulsive manifestation of AS although some studies attribute running to a panic-like response. Increase in central ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2007.02.017

    authors: Vinogradova LV,Shatskova AB,Tuomisto L

    更新日期:2007-05-07 00:00:00

  • Comparison of morphology and physiology of synapses formed at ectopic and original endplate sites in frog muscle.

    abstract::The properties of junctions formed de novo in ectopic regions of muscle were studied and compared to those of endplates reinnervated after nerve crush and to normals. The nerve to the frog cutaneous pectoris muscle was transposed and implanted onto an endplate-free (ectopic) region of that muscle, while the endplate-c...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(82)90673-4

    authors: Ding R

    更新日期:1982-12-16 00:00:00

  • Role of excitatory amino-acids in diethyldithiocarbamate-induced cell death in mesencephalic cultures.

    abstract::The effects of diethyldithiocarbamate (DDC) and DDC plus glutamate on mesencephalic cell cultures were investigated. DDC 10 microM was toxic for cell cultures as assessed by observation under a phase-contrast microscope and the drop in [3H]dopamine uptake. Moreover, DDC 1 microM greatly potentiated cell death induced ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(94)01457-s

    authors: Vaglini F,Pardini C,Maggio R,Corsini GU

    更新日期:1995-03-13 00:00:00

  • Increased GABA binding in mouse brain following acute swim stress.

    abstract::Acute swim stress of mice produces increases in the density of high and low affinity binding sites in the brain for the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), together with analgesia as measured by an increase in tail flick latency. Apparent tolerance develops in repeated swimming with analgesia a...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(81)90524-2

    authors: Skerritt JH,Trisdikoon P,Johnston GA

    更新日期:1981-06-29 00:00:00

  • Growth hormone (GH), thyroid-stimulating hormone (TSH), and luteinizing hormone (LH)-like peptides in the rodent brain: non-parallel ontogenetic development with pituitary counterparts.

    abstract::Brain and anterior pituitary growth hormone (GH), thyroid-stimulating hormone (TSH) and luteinizing hormone (LH) were measured during fetal, neonatal, and pubertal life and into adulthood. Immunoassayable GH and TSH could be found in the fetal whole brain before their detection in the fetal pituitary. Developmental pa...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0165-3806(82)90186-9

    authors: Hojvat S,Emanuele N,Baker G,Connick E,Kirsteins L,Lawrence AM

    更新日期:1982-08-01 00:00:00

  • The alteration of glucocorticoid receptor-immunoreactivity in the rat forebrain following short-term and long-term adrenalectomy.

    abstract::To examine the effect of short-term and long-term adrenalectomy (ADX) on the glucocorticoid receptor (GR) expression, we performed an immunohistochemical study on the rat forebrain. One day after ADX, the GR-immunoreactivity significantly decreased or disappeared in most forebrain structures, while relatively strong G...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:

    authors: Visser DT,Hu Z,Pasterkamp RJ,Morimoto M,Kawata M

    更新日期:1996-08-12 00:00:00

  • Evidence for pore-like opening of the blood-brain barrier following forebrain ischemia in rats.

    abstract::The nature of the delayed blood-brain barrier (BBB) opening that occurs in rats subjected to forebrain ischemia by the technique of two-vessel (carotid) occlusion plus hypovolemic hypotension (2VO ischemia) was probed by examining the simultaneous, trans-barrier movement of two hydrophilic, normally poorly permeative ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(97)00323-5

    authors: Preston E,Foster DO

    更新日期:1997-06-27 00:00:00

  • Commissural and ipsilateral internuclear connection of vestibular nuclear complex of the cat.

    abstract::Commissural and ipsilateral intrinsic connections of the vestibular nuclear complex of cats were investigated using retrograde transport of horseradish peroxidase (HRP). HRP was microiontophoretically injected into limited areas (0.2-0.5 mm in diameter) of the respective vestibular nuclei. In the commissural connectio...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(85)91474-x

    authors: Ito J,Matsuoka I,Sasa M,Takaori S

    更新日期:1985-08-19 00:00:00

  • Effects of angiotensin II on dopamine and serotonin turnover in the striatum of conscious rats.

    abstract::This study was designed to evaluate the functional significance of angiotensin II (Ang II) receptors identified by previous receptor autoradiography studies to be located presynaptically on terminals of dopaminergic neurones projecting to the striatum. Microdialysis was performed in the striatum of conscious freely mo...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(93)90902-y

    authors: Mendelsohn FA,Jenkins TA,Berkovic SF

    更新日期:1993-06-11 00:00:00

  • Afferent projections to the hypothalamic area controlling emotional responses (HACER).

    abstract::The Mesulam technique for horseradish peroxidase was used to study the subcortical afferent projections to a location in the hypothalamus that has been shown to control the complete cardiovascular (CV) response accompanying a specific emotional behavior. Major projections common to all baboons injected included the la...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(82)90389-4

    authors: Devito JL,Smith OA

    更新日期:1982-12-09 00:00:00

  • Effect of cocaine on the 5-HT3 receptor-mediated ion current in Xenopus oocytes.

    abstract::The cloned 5-HT3 receptor from NCB-20 neuroblastoma cells was expressed in Xenopus oocytes. In these oocytes, 5-HT, the selective 5-HT3 receptor agonists, 2-methyl-5-HT and m-chlorophenylbiguanide activated an inward current which was sensitive to the specific 5-HT3 receptor antagonist LY278584. Cocaine (0.1 to 10 mic...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(94)01316-a

    authors: Fan P,Oz M,Zhang L,Weight FF

    更新日期:1995-03-06 00:00:00

  • Measurement of cerebral microvessel diameters after embolic stroke in rat using quantitative laser scanning confocal microscopy.

    abstract::Perfusion of the microcirculation after stroke is central to preserving neuronal function and improving functional outcome. Using laser scanning confocal microscopy (LSCM) and a novel computer software program, MIRAGE, we measured a reduction in cerebral microvessel diameter after 1 and 4 h of embolic middle cerebral ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(00)02543-9

    authors: Morris DC,Davies K,Zhang Z,Chopp M

    更新日期:2000-09-08 00:00:00

  • A comparison of the effects of pentobarbital and diphenylhydantoin on the GABA sensitivity and excitability of adult sensory ganglion cells.

    abstract::The actions of pentobarbital (PB) and diphenylhydantoin (DPH) have been studied on neurons of dorsal root ganglia from adult rats. At anesthetic level (i.e. 1--2 x 10(-4) M), PB greatly enhanced neuronal responses to gamma-aminobutyric acid (GABA); at 10(-3) M PB caused a small depolarization and profoundly attenuated...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(81)90370-x

    authors: Connors BW

    更新日期:1981-03-02 00:00:00

  • Role of V1a vasopressin receptors in the control of aggression in Syrian hamsters.

    abstract::The present study investigated the hypothesis that social isolation increases aggression by increasing the number of V1a vasopressin receptors in the anterior hypothalamus (AH). Male hamsters were randomly assigned to a group that was allowed to interact with a small nonaggressive hamster three times each week for 3 w...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2005.12.081

    authors: Albers HE,Dean A,Karom MC,Smith D,Huhman KL

    更新日期:2006-02-16 00:00:00

  • Involvement of calmodulin-dependent protein kinase II in carbachol-induced rhythmic activity in the hippocampus of the rat.

    abstract::The role of calcium and protein kinases in rhythmic activity induced by muscarinic receptor activation in the CA1 area in rat hippocampal slices was investigated. Extracellular recording showed that carbachol (20 microM) induced synchronized field potential activity with a dominant frequency of 7.39+/-0.68 Hz. Pretrea...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(00)02331-3

    authors: Alberi S,Boeijinga PH,Raggenbass M,Boddeke HW

    更新日期:2000-07-28 00:00:00

  • Some electrophysiological and pharmacological properties of the cortical, noradrenergic projection of the locus coeruleus in the rat.

    abstract::The effect of repetitive stimulation of the locus coeruleus (LC) on the discharge rate of spontaneously active neurons of the visual, rostral and cingulate cortex was investigated in untreated and catecholamine-depleted rats under chloral hydrate anesthesia. In untreated animals, the inhibitory transsynaptic effects p...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(80)90251-6

    authors: Olpe HR,Glatt A,Laszlo J,Schellenberg A

    更新日期:1980-03-17 00:00:00

  • LDL and HDL affect nitric oxide metabolism in human astrocytoma cells.

    abstract::Astrocytes provide structural, trophic and metabolic support to neurons and modulate synaptic activity. Under physiological conditions, neuronal-derived nitric oxide (NO) plays an important role in the modulation of a variety of central nervous system (CNS) functions. NO, although short lived, can travel sufficient di...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2004.06.026

    authors: Nanetti L,Vignini A,Moroni C,Pessina GP,Mazzanti L

    更新日期:2004-09-10 00:00:00