Fine structure of GABAergic neurons and synapses in the human dentate gyrus.

abstract：:Seventy-two hybridoma lines that produce monoclonal antibodies to molecules of a rat synaptosomal plasma membrane fraction (SPM) were generated. The topographical distribution of the antigens in the cerebellum and other areas of the brain was studied by light microscopy immunocytochemistry. Some of the antibodies reco...

journal_title：Brain research

authors： De Blas A,Kuljis RO,Cherwinski HM

更新日期：1984-11-26 00:00:00

abstract：:Circadian and neural mechanisms important for the organization of reproductive behavior in the male golden hamster were examined. The sexual behavior of male hamsters exhibits diel variations; males are quicker to initiate copulation and to ejaculate in the dark phase than in the light phase of a daily light-dark cycl...

journal_title：Brain research

authors： Eskes GA

更新日期：1984-02-13 00:00:00

abstract：:The opposing actions of diphenylhydantoin (DPH) and calcium on the level of [32P]phosphate incorporation into particular rat and human brain proteins have been demonstrated in this study by employing the techniques of acrylamide gel electrophoresis and autoradiography. In the presence of calcium several brain proteins...

journal_title：Brain research

authors： DeLorenzo RJ

更新日期：1977-09-23 00:00:00

abstract：:A pair of neurons exhibiting postinhibitory rebound, if connected through reciprocally inhibitory chemical synapses, will exhibit a stable pattern of alternating bursts. If two such oscillating pairs, of similar but not identical properties are connected by means of an electrical synapse and an inhibitory chemical syn...

journal_title：Brain research

authors： Mulloney B,Perkel DH,Budelli RW

更新日期：1981-12-14 00:00:00

abstract：:There are sex differences in the neurochemistry of brainstem nuclei that participate in the control of breathing as well as sex differences in respiratory responses to hypoxia. Central chemoreception refers to the detection within the brain of minute changes in carbon dioxide (CO(2)) levels and the subsequent modulati...

journal_title：Brain research

authors： Niblock MM,Gao H,Li A,Jeffress EC,Murphy M,Nattie EE

更新日期：2010-01-22 00:00:00

abstract：:This study examined the involvement of N-methyl-D-aspartate receptors (NMDARs) in experience-dependent synaptic plasticity. Rats chronically received an NMDA receptor antagonist (AP5) or saline (SAL) and were exposed to individual cages (IC) or environmental enrichment (EC). AP5 impaired measures of hippocampal-depend...

journal_title：Brain research

authors： Foster TC,Fugger HN,Cunningham SG

更新日期：2000-07-14 00:00:00

abstract：:Male laboratory rats were raised in two colonies, each of 27 rats, and then given intraventricular injections of the norepinephrine neurotoxin 6-hydroxydopamine (6-OHDA) or the serotonin neurotoxin 5,6-dihydroxytryptamine (5,6-DHT) or saline. They were then returned to their enclosure and behavior during the next 50 d...

journal_title：Brain research

authors： Ellison G

更新日期：1976-02-13 00:00:00

abstract：:Opiates and cannabinoids are among the most widely consumed habit-forming drugs in humans. Several studies have demonstrated the existence of interactions between both kind of drugs in a variety of effects and experimental models. The present study has been focused to determine whether perinatal delta9-tetrahydrocanna...

journal_title：Brain research

authors： Vela G,Martín S,García-Gil L,Crespo JA,Ruiz-Gayo M,Fernández-Ruiz JJ,García-Lecumberri C,Pélaprat D,Fuentes JA,Ramos JA,Ambrosio E

更新日期：1998-10-05 00:00:00

abstract：:Sex steroid hormones regulate various neural functions that control vertebrate sociosexual behavior. A number of sex steroids can be synthesized de novo in the brain, including estrogens by the enzyme aromatase. Aromatase, the neuropeptides arginine vasotocin/vasopressin, and the monoamine neurotransmitter dopamine ha...

journal_title：Brain research

authors： Marsh KE,Creutz LM,Hawkins MB,Godwin J

更新日期：2006-12-18 00:00:00

abstract：:In addition to its stimulatory effect on prolactin release, the neuropeptide prolactin releasing peptide (PrRP) has been shown to be a mediator of the stress response. To analyze the neurochemical properties of the cells responsive to PrRP and involved in stress modulation, we examined PrRP receptor co-expression with...

journal_title：Brain research

authors： Lin SH,Leslie FM,Civelli O

更新日期：2002-10-11 00:00:00

abstract：:Severed medial giant axons in crayfish can be rejoined in vitro with polyethylene glycol (PEG) to produce axoplasmic continuity and through transmission of action potentials. Severed axon-like processes of a mammalian neuroblastoma/glioma cell line seem to be rejoined to the cell body using PEG in tissue culture. Our ...

journal_title：Brain research

authors： Bittner GD,Ballinger ML,Raymond MA

更新日期：1986-03-05 00:00:00

abstract：:Single neurons in culture express a heterogeneity of neurotransmitter receptor subtypes. The study of the effects of neurotransmitters on neuronal function is complicated by this heterogeneity. It would therefore be useful to be able to identify live neurons that express the receptors of interest and then use these ne...

journal_title：Brain research

authors： Hoyt KR,Reynolds IJ

更新日期：1996-08-26 00:00:00

abstract：:Dentate granule cells can be selectively destroyed by intrahippocampal injections of colchicine. This study evaluates the consequences of granule cell destruction on blood pressure regulation in the normotensive Wistar-Kyoto (WKY) and spontaneously hypertensive rat (SHR). Bilateral destruction of dentate granule cells...

journal_title：Brain research

authors： Privette TH,Wang JQ,Ingenito AJ,Terrian DM

更新日期：1994-09-12 00:00:00

abstract：:Intracerebroventricular (i.c.v.) infusion of sodium in rats increases cerebrospinal fluid (CSF) [Na], mimicking the effects of a high salt diet in salt-sensitive strains and causing sympathetic hyperactivity and a pressor response that are mediated via both an endogenous brain ouabainlike substance (OLS) and the brain...

journal_title：Brain research

authors： Van Huysse JW,Hou X

更新日期：2004-09-24 00:00:00

abstract：:Marmoset monkeys (Callithrix jacchus) with bilateral transections of the anterior temporal stem, amygdala and fornix were unable to relearn a 2-choice object discrimination first learnt prior to surgery, and were very severely impaired at relearning a concurrent object discrimination task which they had learnt and rel...

journal_title：Brain research

authors： Maclean CJ,Gaffan D,Baker HF,Ridley RM

更新日期：2001-01-05 00:00:00

abstract：:Decision making is commonly conceived to reflect the interplay of mutually antagonistic systems: executive processes must inhibit affective information to make adaptive choices. Consistent with this interpretation, prior studies have shown that the dorsolateral prefrontal cortex (dlPFC) is activated by executive proce...

journal_title：Brain research

authors： Mullette-Gillman OA,Detwiler JM,Winecoff A,Dobbins I,Huettel SA

更新日期：2011-06-13 00:00:00

abstract：:Immunohistochemical localization of brain-derived neurotrophic factor (BDNF) in the monkey brain was investigated using a polyclonal anti-BDNF antibody produced in our laboratory. The antibody recognized a single band in monkey brain homogenates, and the estimated molecular weight was approximately 14 kDa, which corre...

journal_title：Brain research

authors： Kawamoto Y,Nakamura S,Kawamata T,Akiguchi I,Kimura J

更新日期：1999-03-13 00:00:00

abstract：:Colchicine was injected into the region of the organum vasculosum lamina terminalis/anterior region of the third cerebral ventricle (OVLT/AV3V) to produce a temporary disruption of the nervous connections of this area and the rest of the anterior hypothalamus, but to maintain the vascular connections intact. Rats were...

journal_title：Brain research

authors： Thornton SN,Sirinathsinghji DJ,Delaney CE

更新日期：1987-12-29 00:00:00

abstract：:Experiments have been performed on pentobarbitone anesthetized or decerebrated rats. The nature of the synchronous rhythmical activity which occurs in the inferior olive following the electrophoretic or systemic administration of harmaline, harmine, dihydro-beta-erythroidine and various other compounds, is described. ...

journal_title：Brain research

authors： Headley PM,Lodge D,Duggan AW

更新日期：1976-01-23 00:00:00

abstract：:This study examined the relationship between the affinity of cholinergic drugs for muscarinic receptor subtypes and their potency in potentiating or inhibiting amphetamine-induced rotation. The ascending nigrostriatal dopaminergic pathway was unilaterally lesioned in male Wistar rats using 6-hydroxydopamine. In these ...

journal_title：Brain research

authors： Hagan JJ,Tonnaer JA,Rijk H,Broekkamp CL,van Delft AM

更新日期：1987-04-28 00:00:00

abstract：:In auditory speech processing, phonological stress functions as an attention holding cue, which facilitates detection of mispronunciations and phonetic deviants in strong syllables as compared to weak ones. Whereas silent reading involves activation of phonological information including word stress, it is not clear wh...

journal_title：Brain research

authors： Kriukova O,Mani N

更新日期：2016-04-01 00:00:00

abstract：:In the present studies, we have evaluated the effects of N-[4-(2-¿[(3-Chlorophenyl)methyl]amino¿ethyl)phenyl]-2-thiophenecarbo ximidamide dihydrochloride (ARL 17477) on recombinant human neuronal NOS (nNOS) and endothelial NOS (eNOS). We then carried out pharmacokinetic studies and measured cortical nitric oxide synth...

journal_title：Brain research

authors： O'Neill MJ,Murray TK,McCarty DR,Hicks CA,Dell CP,Patrick KE,Ward MA,Osborne DJ,Wiernicki TR,Roman CR,Lodge D,Fleisch JH,Singh J

更新日期：2000-07-21 00:00:00

abstract：:Afferents to th midbrain dorsal and median raphe nuclei in the rat were studied by means of the horseradish peroxidase (HRP) retrograde transport method. The HRP was given by means of a modified iontophoretic delivery technique. This technique permitted an efficient and localized deposition of a high concentration of ...

journal_title：Brain research

authors： Aghajanian GK,Wang RY

更新日期：1977-02-18 00:00:00

abstract：:This study determined if vasopressin generates superoxide anion (O2(-)) in a cyclooxygenase dependent manner and if such production contributes to impairment of dilation to activators of ATP sensitive K(+) (K(ATP)) and calcium sensitive K(+) (K(ca)) channels following fluid percussion brain injury (FPI) in newborn pig...

journal_title：Brain research

authors： Armstead WM

更新日期：2001-08-10 00:00:00

abstract：:The senescence-accelerated mouse prone 8 (SAMP8) is a novel aging model characterized by early onset and rapid advancement of senescence. In the present study, 6-month-old male SAMP8 mice were orally administered icariin (75, 150mg/kg) for 15weeks. Mice were submitted to passageway water maze test and step-down passiv...

journal_title：Brain research

authors： He XL,Zhou WQ,Bi MG,Du GH

更新日期：2010-06-02 00:00:00

abstract：:The myosin S-1 subfragment was used to label actin filaments in the developing rat brain. The results show actin filaments present throughout the dendritic region with highest concentrations within growth cones and regions of spine development. Between 6 and 25 days postnatal, spines became more complex and actin fila...

journal_title：Brain research

authors： Markham JA,Fifková E

更新日期：1986-06-01 00:00:00

abstract：:Extracellular recording was used to investigate spontaneously active neurons in all four major nuclei of the rat vestibular nuclear complex (VNC) in brainstem slices. The density of spontaneously active neurons was highest in the medial vestibular nucleus (MVN), slightly lower in the superior (SuVN) and spinal (SpVN) ...

journal_title：Brain research

authors： Sun Y,Waller HJ,Godfrey DA,Rubin AM

更新日期：2002-04-26 00:00:00

abstract：:To gain insight into ATP-binding cassette transporter A1 (ABCA1) function and its potential role in AD pathology, we analyzed the expression of the cholesterol transporter ABCA1 in postmortem hippocampus from persons at different stages of dementia and AD associated neuropathology relative to cognitively intact normal...

journal_title：Brain research

authors： Akram A,Schmeidler J,Katsel P,Hof PR,Haroutunian V

更新日期：2010-03-08 00:00:00

abstract：:We have examined the role of the octopamine-containing buccal OC interneuron in the fictive feeding rhythm generated by depolarizing a modulatory interneuron, SO, in the isolated central nervous system (CNS) of Lymnaea stagnalis. Before stimulating the SO, the initial fictive feeding rate was 2.0+/-0.37 bites/min (mea...

journal_title：Brain research

authors： Elliott CJ,Vehovszky A

更新日期：2000-12-22 00:00:00

abstract：:It has been well established that the mitochondrial ATP-sensitive potassium channel (mitoK(ATP)) opener, diazoxide, has protective effects on the heart and brain following ischemia/reperfusion injury. However, the mechanism of the neuroprotective effects of diazoxide remains unclear. This study highlights the anti-apo...

journal_title：Brain research

authors： Zhang H,Wang ZQ,Zhao DY,Zheng DM,Feng J,Song LC,Luo Y

更新日期：2011-01-25 00:00:00