Abstract：
:The effects of diethyldithiocarbamate (DDC) and DDC plus glutamate on mesencephalic cell cultures were investigated. DDC 10 microM was toxic for cell cultures as assessed by observation under a phase-contrast microscope and the drop in [3H]dopamine uptake. Moreover, DDC 1 microM greatly potentiated cell death induced by glutamate 10 and 50 microM. (+)MK801, a selective non-competitive antagonist of NMDA receptors, completely prevented the toxicity of the two neurotoxins.
journal_name
Brain Resjournal_title
Brain researchauthors
Vaglini F,Pardini C,Maggio R,Corsini GUdoi
10.1016/0006-8993(94)01457-ssubject
Has Abstractpub_date
1995-03-13 00:00:00pages
127-32issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(94)01457-Sjournal_volume
674pub_type
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