Abstract：
:The cerebellum and inferior olive of adult homozygous leaner mutant mice (tgIa/tgIa) were examined using anti-vitamin D-dependent calcium binding protein immunohistochemistry, and Nissl staining. The immunohistochemical staining revealed that cerebellar Purkinje cell loss in leaner is restricted to alternating saggital compartments of the cerebellar cortex. The absence of Purkinje cells from specific sagittal zones of the cerebellar cortex apparently results in a loss of immunochemical staining of Purkinje cell axons and terminals from specific regions of the leaner cerebellar nuclear complex. A specific pattern of atrophy was also observed in the leaner inferior olive.
journal_name
Brain Resjournal_title
Brain researchauthors
Heckroth JA,Abbott LCdoi
10.1016/s0006-8993(09)90014-2subject
Has Abstractpub_date
1994-09-26 00:00:00pages
93-104issue
1-2eissn
0006-8993issn
1872-6240pii
S0006-8993(09)90014-2journal_volume
658pub_type
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