Abstract：
:The extensive outgrowth from explanted goldfish retina in vitro stimulated by the axotomy of the optic nerve several days prior to the explantation, enables a more direct examination of the events which accompany optic nerve regeneration. Thus far neuritic outgrowth has been obtained in serum-containing medium. In the present report we demonstrate for the first time that factor(s) from adult goldfish brain can support neuritic outgrowth from retinal explant and replace the serum. This finding suggests that goldfish neuronotrophic factor(s) are active on retinal ganglia cells. Under the same experimental conditions nerve growth factor from submaxillary gland did not exhibit outgrowth stimulatory activity.
journal_name
Brain Resjournal_title
Brain researchauthors
Schwartz M,Mizrachi Y,Eshhar Ndoi
10.1016/0165-3806(82)90073-6subject
Has Abstractpub_date
1982-01-01 00:00:00pages
29-35issue
1eissn
0006-8993issn
1872-6240journal_volume
255pub_type
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