Transforming growth factor-beta 1 promotes re-elongation of injured axons of cultured rat hippocampal neurons.

abstract：:Neuron-specific enolase (NSE) has been localized only in neurons and cells with characteristics of neurons. The immunocytochemical localization of NSE was examined in guinea pig cochleae to determine if hair cells, which have some neuronal characteristics, would show NSE-like immunoreactive labeling. NSE-like immunore...

journal_title：Brain research

authors： Altschuler RA,Reeks KA,Marangos PJ,Fex J

更新日期：1985-02-18 00:00:00

abstract：:The distribution of cells expressing mu-receptor mRNA and mu-receptor binding sites were compared in brain and spinal cord tissue sections using a combination of in situ hybridization and receptor autoradiographic techniques. mu-Receptor mRNA was visualized with a 35S-labeled cRNA probe directed to transmembrane III-V...

journal_title：Brain research

authors： Mansour A,Fox CA,Thompson RC,Akil H,Watson SJ

更新日期：1994-04-18 00:00:00

abstract：:During a simple reaction time task using auditory or visual stimuli, a total of 96 single units were recorded from the dorsolateral prefrontal cortex of macaque monkeys. These monkeys were trained to depress a lever for a fixed period which produced a tone burst or a small spot of light. After a variable period, the s...

journal_title：Brain research

authors： Ito SI

更新日期：1982-09-09 00:00:00

abstract：:The role of calcium and protein kinases in rhythmic activity induced by muscarinic receptor activation in the CA1 area in rat hippocampal slices was investigated. Extracellular recording showed that carbachol (20 microM) induced synchronized field potential activity with a dominant frequency of 7.39+/-0.68 Hz. Pretrea...

journal_title：Brain research

authors： Alberi S,Boeijinga PH,Raggenbass M,Boddeke HW

更新日期：2000-07-28 00:00:00

abstract：:In the present experiment we tested the hypothesis that early interference with noradrenaline transmission can have permanent consequences for brain function in adulthood. Neonatal depletion of noradrenaline by daily subcutaneous injections of clonidine results in supersensitivity to noradrenaline in adult hippocampal...

journal_title：Brain research

authors： Gorter JA,Kamphuis W,Huisman E,Bos NP,Mirmiran M

更新日期：1990-12-03 00:00:00

abstract：:Dissociated striatal neurons exhibited increased neurite outgrowth when co-cultured with myenteric plexus explants. Enriched enteric neurons or enriched enteric glia produced a less marked response; non-ganglionic cells had no effect. Increases in striatal neuron and glial cell numbers were seen in all co-cultures. Te...

journal_title：Brain research

authors： Höpker VH,Saffrey MJ,Burnstock G

更新日期：1994-06-20 00:00:00

abstract：:Stereotaxic microinjections of the excitotoxin, ibotenic acid, were made into the striatum, hippocampus or cerebellum of the immature (7-day-old) rat. Two days later, pups were decapitated and the brains processed for light microscopic examination or neurochemical analyses. 10 micrograms ibotenate caused a complete lo...

journal_title：Brain research

authors： Steiner HX,McBean GJ,Köhler C,Roberts PJ,Schwarcz R

更新日期：1984-07-30 00:00:00

abstract：:Glucocorticoid receptor (Gr) concentrations in the rat brain are low at the time of birth and increase towards adult levels during the first two weeks of life. Brief, daily handling of pups for the first 21 days postnatally has been found to permanently increase Gr concentrations within the hippocampus. Thus, the deve...

journal_title：Brain research

authors： Meaney MJ,Aitken DH

更新日期：1985-10-01 00:00:00

abstract：:The relationship between the dorsal raphe neurons projecting to the caudate-putamen and those projecting to the substantia nigra was investigated using a fluorescent retrograde double labeling technique in the rat. The majority of the dorsal raphe neurons projecting to the substantia nigra were found to project also t...

journal_title：Brain research

authors： van der Kooy D,Hattori T

更新日期：1980-03-17 00:00:00

abstract：:Movement of fragmented DNA in dendrites of retinal neurons during the apoptotic cell death was investigated. The time-course of the movement of fragmented DNA in dendrites of retinal neurons undergoing apoptotic cell death induced by intravitreal N-methyl-d-aspartate (NMDA) injection were examined by in situ terminal ...

journal_title：Brain research

authors： Hara A,Niwa M,Kumada M,Kitaori N,Yamamoto T,Kozawa O,Mori H

更新日期：2004-05-08 00:00:00

abstract：:Mice were treated with dopamine (DA) receptor agonist and antagonist drugs: Agonists: (+/-)-SKF 38393 ((+/-)-1-phenyl-2,3,4, 5-tetrahydro-(1H)-3-benzazepine-7,8-diol) [DA D1-like]; bromocriptine, [DA D2 selective]; quinpirole, [DA D2/D3 preferring]; (+/-)-7-hydroxy-dipropylamino-tetralin (7-OH-DPAT), [DA D3/D2 preferr...

journal_title：Brain research

authors： Cho S,Duchemin AM,Neff NH,Hadjiconstantinou M

更新日期：1999-06-05 00:00:00

abstract：:Neural correlates of conscious awareness can be comfortably studied when awareness of the target stimuli is a varying dependent variable in the experimental conditions where the key independent variables are kept invariant. We presented vernier targets backward masked by an invariant grating with invariant SOA. EEG da...

journal_title：Brain research

authors： Aru J,Bachmann T

更新日期：2009-05-19 00:00:00

abstract：:Repeated intermittent administration of amphetamines acutely increases appetitive and consummatory aspects of motivated behaviors as well as general activity and exploratory behavior, including voluntary running wheel activity. Subsequently, if the drug is withdrawn, the frequency of these behaviors decreases, which i...

journal_title：Brain research

authors： Kitanaka N,Kitanaka J,Hall FS,Uhl GR,Watabe K,Kubo H,Takahashi H,Tatsuta T,Morita Y,Takemura M

更新日期：2012-01-06 00:00:00

abstract：:The opioid peptides Leu-enkephalin, Met-enkephalin and D-Ala2-Met-enkephalinamide were injected at various concentrations into the neocortex and hippocampus of rats to examine their effects on EEG activity and DC potentials. All three compounds were found to elicit spreading depression (SD) in both structures. Higher ...

journal_title：Brain research

authors： Sprick U,Oitzl MS,Ornstein K,Huston JP

更新日期：1981-04-06 00:00:00

abstract：:Basic fibroblast growth factor (b-FGF) and alpha melanocyte stimulating hormone (alpha-MSH) were tested for their ability to promote axonal elongation on E14 fetal rat spinal cord cell culture, and to support cell survival. A similar development of neurite was observed in alpha-MSH treated cultures or in control cultu...

journal_title：Brain research

authors： Peulve P,Laquerriere A,Hemet J,Tadie M

更新日期：1994-08-22 00:00:00

abstract：:Nerve growth factor (NGF) treatment, given as a single 200 BU intraocular injection at the time of optic nerve transection, was found to significantly accelerate the retinal ganglion cell response to axotomy in the newt (Notophthalmus viridescens). In the control series the per cent of neurons in the retinal ganglion ...

journal_title：Brain research

authors： Turner JE,Delaney RK

更新日期：1979-08-03 00:00:00

abstract：:Our previous work has revealed increased nitric oxide (NO) production in the cochlear perilymph following noise stress. However, it is not clear if the increase of NO is related to iNOS and whether NO-related oxidative stress can cause vascular tissue damage. In this study, iNOS immunoreactivity, NO production, and re...

journal_title：Brain research

authors： Shi X,Nuttall AL

更新日期：2003-03-28 00:00:00

abstract：:Infection of neonatal mice with ts1, the neuropathogenic mutant of the Moloney murine leukemia virus, results in motor neuronal death in the brainstem and the spinal cord, with gliosis and demyelination, but no inflammatory cell infiltration into the CNS. To evaluate the possible mechanism(s) of ts1-induced neuropatho...

journal_title：Brain research

authors： Choe W,Stoica G,Lynn W,Wong PK

更新日期：1998-01-01 00:00:00

abstract：:Weaver mutant mice alternated above chance levels but less often than normal mice in a 2-trial spontaneous alternation test. When the inter-trial (or retention) interval was manipulated, the weaver mutants alternated above chance levels only at the shortest (15 s) but not at the longest (4 or 5 min) intervals, contrar...

journal_title：Brain research

authors： Lalonde R

更新日期：1986-11-19 00:00:00

abstract：:Despite insights into an increasingly significant role for delta opioid receptors in thermoregulation, it is unclear whether delta receptors located in the brain or periphery play the more critical role in body temperature regulation. Moreover, it is not entirely clear which delta receptor phenotype, delta1 or delta2,...

journal_title：Brain research

authors： Rawls SM,Hewson JM,Inan S,Cowan A

更新日期：2005-07-05 00:00:00

abstract：:A combined retrograde transport and immunocytochemical study was carried out to determine the projections of the large glycine-immunoreactive neurons in the ventral cochlear nucleus of the guinea pig. Horseradish peroxidase (HRP) was injected into the contralateral cochlear nucleus, and cochlear nucleus sections were ...

journal_title：Brain research

authors： Wenthold RJ

更新日期：1987-07-07 00:00:00

abstract：:Recent physiological evidence indicates that vagal postganglionic control of left ventricular contractility is mediated by neurons found in a ventricular epicardial fat pad ganglion. In the dog this region has been referred to as the cranial medial ventricular (CMV) ganglion [J.L. Ardell, Structure and function of mam...

journal_title：Brain research

authors： Massari VJ,Dickerson LW,Gray AL,Lauenstein JM,Blinder KJ,Newsome JT,Rodak DJ,Fleming TJ,Gatti PJ,Gillis RA

更新日期：1998-08-17 00:00:00

abstract：:Serotonin (5-HT) immunostained sections were analyzed using integrated optical density (IOD) measures obtained throughout the dorsal raphe nucleus (DRN) in Mongolian gerbils at selected times during a 12:12 h light:dark cycle. Substantial diurnal variation occurred in 5-HT neuronal staining density, with lowest and hi...

journal_title：Brain research

authors： Birkett M,Fite KV

更新日期：2005-02-09 00:00:00

abstract：:Receptors for alpha-bungarotoxin are found on the surface of parasympathetic neurons in the frog cardiac ganglion by light microscopic autoradiography. Competition studies suggest that these receptors are cholinergic and indicate that they are also recognized by neuronal bungarotoxin (kappa-bungarotoxin). These recept...

journal_title：Brain research

authors： Sargent PB,Garrett EN

更新日期：1995-05-22 00:00:00

abstract：:The action of 5-hydroxytryptamine (5-HT) via the 5-HT1A receptor on dissociated rat dorsal raphe neurons was characterized under the whole-cell mode by using the nystatin-perforated patch-clamp technique. Under voltage-clamp conditions, 5-HT induced an inwardly rectifying K+ current (I5-HT) in a concentration-dependen...

journal_title：Brain research

authors： Katayama J,Yakushiji T,Akaike N

更新日期：1997-01-16 00:00:00

abstract：:Even though animal and human studies show alterations in dopamine transporter (DAT) sites after alcohol withdrawal, the role of DAT in influencing either alcoholic or depressive behavior has not been examined extensively. Given that the Wistar-Kyoto (WKY) rat is a putative animal model of depressive behavior, the pres...

journal_title：Brain research

authors： Jiao X,Paré WP,Tejani-Butt SM

更新日期：2006-02-16 00:00:00

abstract：:The omega-3 fatty acids are essential dietary nutrients and one of their important roles is providing the fatty acid with 22 carbons and 6 double bonds known as docosahexaenoic acid (DHA) for nervous tissue growth and function. Inadequate intakes of omega-3 fatty acids decrease DHA and increase omega-6 fatty acids in ...

journal_title：Brain research

authors： Innis SM

更新日期：2008-10-27 00:00:00

abstract：:Differential circadian rhythms in 5-HT levels were found in the hypothalamus and pineal (but not in the cortex, hippocampus or midbrain) in ferrets kept in either long (14 h light/10 h dark) or short (8 h light/16 h dark) photoperiods. 5-HT decreased during the first 6 h of illumination in all areas examined from anim...

journal_title：Brain research

authors： Yates CA,Herbert J

更新日期：1979-11-02 00:00:00

abstract：:We have recently reported spinal blood flow-metabolism uncoupling in an amyotrophic lateral sclerosis (ALS) animal model using Cu/Zn-superoxide dismutase 1 (SOD1)-transgenic (Tg) mice, suggesting a relative hypoxia in the spinal cord. However, the hypoxic stress sensor pathway has not been well studied in ALS. Here, w...

journal_title：Brain research

authors： Sato K,Morimoto N,Kurata T,Mimoto T,Miyazaki K,Ikeda Y,Abe K

更新日期：2012-09-14 00:00:00

abstract：BACKGROUND:Chronic exposure to estradiol-17β (E2) in adult female rats increases mean arterial pressure by stimulating superoxide production in the rostral ventrolateral medulla (RVLM). However the mechanisms behind this phenomenon are unknown. We hypothesized that E2 exposure induces the gene expression of cytokines, ...

journal_title：Brain research

authors： Subramanian M,Hahn-Townsend C,Clark KA,MohanKumar SM,MohanKumar PS

更新日期：2015-11-19 00:00:00