LM and EM immunolocalization of the gap junctional protein connexin 43 in rat brain.

abstract：:The central nervous system of the mollusc Helix pomatia was stimulated with NO donors sodium nitroprusside (SNP), S-nitroso-N-acetylpenicillamine (SNAP) or hydroxylamine, in the presence of a phosphodiesterase inhibitor 1-methyl-3-isobutylxanthine (IBMX). Radioimmunoassay revealed that all of the three NO donors signi...

journal_title：Brain research

authors： Huang S,Kerschbaum HH,Hermann A

更新日期：1998-01-12 00:00:00

abstract：:Adipose-derived stem cells (ASCs) are readily accessible multipotent mesenchymal stem cells and are known to secrete multiple growth factors, and thereby to have cytoprotective effects in various injury models. In the present study, the authors investigated the neuroprotective effect of ASCs in an intracerebral hemorr...

journal_title：Brain research

authors： Kim JM,Lee ST,Chu K,Jung KH,Song EC,Kim SJ,Sinn DI,Kim JH,Park DK,Kang KM,Hyung Hong N,Park HK,Won CH,Kim KH,Kim M,Kun Lee S,Roh JK

更新日期：2007-12-05 00:00:00

abstract：:An effective animal model for elucidating the neurobiological basis of human smoking should simulate important aspects of this behavior. Therefore, a 23 h unlimited access nicotine self-administration model was used to compare inbred Lewis rats, which have a propensity to self-administer drugs of abuse, to inbred Fish...

journal_title：Brain research

authors： Brower VG,Fu Y,Matta SG,Sharp BM

更新日期：2002-03-15 00:00:00

abstract：:This paper describes carbon fibre electrodes that can simultaneously monitor changes in ascorbic acid, dihydroxyphenylacetic acid (DOPAC), 5-hydroxyindoleacetic acid (5HIAA) and homovanillic acid (HVA) in vivo in the rat striatum using differential pulse voltammetry. The separation between DOPAC and 5HIAA oxidation is...

journal_title：Brain research

authors： Crespi F,Sharp T,Maidment NT,Marsden CA

更新日期：1984-11-19 00:00:00

abstract：:While genetic predisposition is a major factor, it is not known how development of attention-deficit/hyperactivity disorder (ADHD) is modulated by early life stress. The spontaneously hypertensive rat (SHR) displays the behavioral characteristics of ADHD (poorly sustained attention, impulsivity, hyperactivity) and is ...

journal_title：Brain research

authors： Sterley TL,Howells FM,Russell VA

更新日期：2016-06-15 00:00:00

abstract：:The present study was undertaken to investigate and compare the properties of noradrenaline release in the locus coeruleus (LC) and prefrontal cortex (PFC). For that aim the dual-probe microdialysis technique was applied for simultaneous detection of noradrenaline levels in the LC and PFC in conscious rats. Calcium om...

journal_title：Brain research

authors： Pudovkina OL,Kawahara Y,de Vries J,Westerink BH

更新日期：2001-07-06 00:00:00

abstract：:This review summarizes the anatomical and functional organization of the frontal cortex of the rat in comparison to primates. Lesions of the primary motor or of the prefrontal cortex of both primates and rodents produce a consistent constellation of symptoms that are strikingly similar across species as diverse as rat...

journal_title：Brain research

authors： Kolb B

更新日期：1984-11-01 00:00:00

abstract：:Unanesthetized adult male rats with indwelling right atrial cannulae were used in the majority of experiments. Morphine (MOR, 3.0 mg/kg) caused a large but transient increase in both GH and PRL levels, which could be prevented with naloxone. Disruption of central noradrenergic function with diethyldithiocarbamate (400...

journal_title：Brain research

authors： Koenig J,Mayfield MA,Coppings RJ,McCann SM,Krulich L

更新日期：1980-09-22 00:00:00

abstract：:Current and voltage responses elicited by increasing or decreasing the concentration of L-glutamate or its analog kainate around isolated cone horizontal cells were measured with patch pipettes using the whole cell recording configuration. Application of these photoreceptor transmitter agonists induced inward currents...

journal_title：Brain research

authors： Perlman I,Knapp AG,Dowling JE

更新日期：1989-05-15 00:00:00

abstract：:The present study investigated the hypothesis that social isolation increases aggression by increasing the number of V1a vasopressin receptors in the anterior hypothalamus (AH). Male hamsters were randomly assigned to a group that was allowed to interact with a small nonaggressive hamster three times each week for 3 w...

journal_title：Brain research

authors： Albers HE,Dean A,Karom MC,Smith D,Huhman KL

更新日期：2006-02-16 00:00:00

abstract：:Levodopa (L-DOPA) is widely used for symptomatic management in Parkinson's disease. We recently showed that (-)-epigallocatechin-3-gallate, a tea polyphenol, not only inhibits L-DOPA methylation, but also protects against oxidative hippocampal neurodegeneration. In the present study, we sought to determine several oth...

journal_title：Brain research

authors： Kang KS,Yamabe N,Wen Y,Fukui M,Zhu BT

更新日期：2013-02-25 00:00:00

abstract：:Nicergoline, a drug used for the treatment of Alzheimer's disease and other types of dementia, was tested for its ability to protect neurons against beta-amyloid toxicity. Pure cultures of rat cortical neurons were challenged with a toxic fragment of beta-amyloid peptide (betaAP(25-35)) and toxicity was assessed after...

journal_title：Brain research

authors： Caraci F,Chisari M,Frasca G,Canonico PL,Battaglia A,Calafiore M,Battaglia G,Bosco P,Nicoletti F,Copani A,Sortino MA

更新日期：2005-06-14 00:00:00

abstract：:This study has examined the retinal synapses of the cat superior colliculus using electron microscope autoradiography and morphometric techniques. The depth of each retinal synapse was measured using a computer-based EM plotter. The area, perimeter, and synapse contact density of selected synapses were calculated usin...

journal_title：Brain research

authors： Mize RR

更新日期：1983-06-20 00:00:00

abstract：:Cytosol androgen receptors were assayed in guinea pig brain and pituitary tissues, using [3H]R1881 as ligand. These receptors had an apparent Kd of 0.04 nM and were androgen-specific (R1881 greater than dihydrotestosterone greater than testosterone = estradiol greater than progesterone). Concentrations of cytosol andr...

journal_title：Brain research

authors： Bonneau M,Ahdieh HB,Thornton JE,Feder HH

更新日期：1987-06-09 00:00:00

abstract：:Endogenous long-duration burst-organizing potentials (driver potentials, DPs) generated by neurons in the lobster cardiac ganglion play a critical role in the ability of the system to generate rhythmic bursts of nerve impulses. The DPs are normally terminated by a voltage-dependent potassium current, but when this is ...

journal_title：Brain research

authors： Berlind A

更新日期：1993-04-23 00:00:00

abstract：:Noradrenergic neurons of the brainstem extend projections throughout the neuraxis to modulate a wide range of processes including attention, arousal, autonomic control and sensory processing. A spinal projection from the locus coeruleus (LC) is thought to regulate nociceptive processing. To characterize and selectivel...

journal_title：Brain research

authors： Li Y,Hickey L,Perrins R,Werlen E,Patel AA,Hirschberg S,Jones MW,Salinas S,Kremer EJ,Pickering AE

更新日期：2016-06-15 00:00:00

abstract：:Upon a physiological and pharmacological challenge, the responsiveness of extracellular glutamate levels in the prefrontal cortex, ventral tegmental area and locus coeruleus were studied using microdialysis. A 10-min handling period was used as a mild stressful stimulus. In all three brain areas, handling induced an i...

journal_title：Brain research

authors： Timmerman W,Cisci G,Nap A,de Vries JB,Westerink BH

更新日期：1999-07-03 00:00:00

abstract：:The dentate gyrus is believed to play an important pathophysiological role during experimentally induced kindling. In this study, we investigated whether an altered content of the calcium binding protein calbindin-D(28k) or an increased intrinsic excitability of hippocampal granule cells contribute to the induction of...

journal_title：Brain research

authors： Dietrich D,Podlogar M,Ortmanns G,Clusmann H,Kral T

更新日期：2005-01-25 00:00:00

abstract：:The [14C]2-deoxyglucose (2-DG) technique has been widely utilized for quantitative measurement of local cerebral metabolic for glucose (1CMRG) in animals. The technique as presently used is limited by the energy of 14C beta-particles, which can travel relatively great distances in tissue. This results in limited audio...

journal_title：Brain research

authors： Alexander GM,Schwartzman RJ,Bell RD,Yu J,Renthal A

更新日期：1981-10-26 00:00:00

abstract：:Intracerebroventricular (i.c.v.) infusion of sodium in rats increases cerebrospinal fluid (CSF) [Na], mimicking the effects of a high salt diet in salt-sensitive strains and causing sympathetic hyperactivity and a pressor response that are mediated via both an endogenous brain ouabainlike substance (OLS) and the brain...

journal_title：Brain research

authors： Van Huysse JW,Hou X

更新日期：2004-09-24 00:00:00

abstract：:Both enkephalin and 5-hydroxytryptamine (5-HT) have been implicated in neural mechanisms underlying the central control of respiration. In view of the role of the nuclei tractus solitarii (NTS) in respiratory regulation, we carried out a study in artificially ventilated, chloralose-anaesthetized cats of the effects of...

journal_title：Brain research

authors： Sessle BJ,Henry JL

更新日期：1985-02-18 00:00:00

abstract：:The localization of the two Ca-activated extralysosomal proteases m-calpain and mu-calpain in the eye of the adult rabbit was examined by immunohistochemistry, using poly- and monoclonal antibodies against the corresponding rabbit antigens. Immunoreactivity against the two forms of calpains was observed in the epithel...

journal_title：Brain research

authors： Persson H,Kawashima S,Karlsson JO

更新日期：1993-05-21 00:00:00

abstract：:Monoclonal antibody N210 (mabN210) recognizes the 210 kdalton neurofilament protein in mammals and gives characteristic immunocytochemical staining of neurofilament-rich processes. For example, in the cerebellum it recognizes myelinated axons and the calyx formed by basket cell axon collaterals. The distribution of ma...

journal_title：Brain research

authors： Maler L,Leclerc N,Hawkes R

更新日期：1986-07-23 00:00:00

abstract：:The synaptic connections between frog retinal ganglion cells and tectal neurons were examined by whole-cell recordings in vivo combined with nystatin perforated patch-clamp technique and pulse-triggered averaging analysis. In five tectal neurons, monosynaptic EPSPs from seven R3 retinal ganglion cells were observed. O...

journal_title：Brain research

authors： Nakagawa H,Kikkawa S,Matsumoto N

更新日期：1994-12-05 00:00:00

abstract：:It was previously reported that chronic food restriction and maintenance of rats at 75-80% of initial body weight enhanced the reward-potentiating effect of D-amphetamine in the lateral hypothalamic self-stimulation (LHSS) paradigm. Moreover, the enhancement reversed in parallel with body weight recovery when ad libit...

journal_title：Brain research

authors： Hao J,Cabeza de Vaca S,Pan Y,Carr KD

更新日期：2006-05-04 00:00:00

abstract：:Median preoptic nucleus (POMe) neurons are innervated by catecholaminergic and neuropeptide Y (NPY)-immunoreactive nerve terminals originating from the catecholamine area of the ventrolateral medulla (VLM). The possibility that such POMe neurons project to the VLM catecholamine area was investigated in the rat. Immuno...

journal_title：Brain research

authors： Kawano H,Masuko S

更新日期：1999-04-17 00:00:00

abstract：:Maternal seizure has adverse effects on brain histology as well as on learning and memory ability in progeny. An enriched environment (EE) is known to promote structural changes in the brain and improve cognitive and motor deficits following a variety of brain injuries. Whether EE treatment in early postnatal periods ...

journal_title：Brain research

authors： Xie T,Wang WP,Jia LJ,Mao ZF,Qu ZZ,Luan SQ,Kan MC

更新日期：2012-08-27 00:00:00

abstract：:Slowness of goal-directed movements is a frequent symptom following cerebellar lesions. So far it has not been demonstrated whether this slowness represents compensation for impaired braking which is a feature of cerebellar dysfunction with the consequence of hypermetria, or whether it is an independent part of cerebe...

journal_title：Brain research

authors： Wild B,Klockgether T,Dichgans J

更新日期：1996-03-25 00:00:00

abstract：:Serotonin 1A receptor (5-HT(1A)R) agonists have emerged as valuable supplements to l-DOPA therapy, demonstrating that they can decrease side effects and enhance motor function in animal models of Parkinson's disease (PD) and human PD patients. The precise mechanism by which these receptors act remains unknown and ther...

journal_title：Brain research

authors： Dupre KB,Eskow KL,Negron G,Bishop C

更新日期：2007-07-16 00:00:00

abstract：:Immunohistochemistry for three calcium-binding proteins calbindin D-28k, calretinin, and parvalbumin revealed neuronal heterogeneity within the GP. Each neurone appeared to express either a single type of calcium binding protein or none at all. The co-localisation of calcium binding proteins was not observed. Combined...

journal_title：Brain research

authors： Cooper AJ,Stanford IM

更新日期：2002-03-08 00:00:00