Post-stress changes in BDNF and Bcl-2 immunoreactivities in hippocampal neurons: effect of chronic administration of olanzapine.

abstract：:We assessed the effects of simulated weightlessness, hindlimb unloading (HU) by 7 days of tail suspension, on noxious mechanically and heat evoked spinal withdrawal reflexes and spinal Fos expression during muscle nociception elicited by intramuscular (i.m.) injection of hypertonic (HT; 5.8%) saline into gastrocnemius...

journal_title：Brain research

authors： Lei J,Pertovaara A,You HJ

更新日期：2015-01-12 00:00:00

abstract：:In the brain, free zinc levels are under the exquisite control of a variety of zinc-regulating systems, in which zinc transporter (ZnT) proteins play a central role. ZnT3, which is prominently expressed in the brain, facilitates the concentration of free zinc in pre-synaptic vesicles. In addition to histochemical stai...

journal_title：Brain research

authors： Lee JY,Kim JS,Byun HR,Palmiter RD,Koh JY

更新日期：2011-10-18 00:00:00

abstract：:Interactive-activation models posit that visual word recognition involves co-activation of orthographic neighbors (e.g., note, node) and competition among them via lateral inhibitory connections. Behavioral evidence of this lexical competition comes from masked priming paradigms, in which target words elicit slower re...

journal_title：Brain research

authors： Meade G,Grainger J,Midgley KJ,Emmorey K,Holcomb PJ

更新日期：2018-04-15 00:00:00

abstract：:The neurotoxic effects of chronic ethanol exposure were investigated in rat hippocampus by electrophysiological analysis of the Schaffer collateral-commissural input to stratum radiatum of CA1. Experimental animals were fed an ethanol-containing liquid diet for 20 weeks but were withdrawn from the special diet at leas...

journal_title：Brain research

authors： Abraham WC,Hunter BE,Zornetzer SF,Walker DW

更新日期：1981-09-28 00:00:00

abstract：:Recent research suggests that in addition to its prominent role in appetitive learning, the nucleus accumbens (NAC) may also be involved in fear conditioning. In the present study, we investigated whether temporary inactivation of the NAC, by injection of tetrodotoxin (TTX), affects acquisition and expression of condi...

journal_title：Brain research

authors： Schwienbacher I,Fendt M,Richardson R,Schnitzler HU

更新日期：2004-11-19 00:00:00

abstract：:Unitary discharges in the efferent ciliary nerves were studied in cervical sympathectomized rabbits. In all, 279 units were recorded and categorized, except 7 units, into the following 3 types from their responses to photic and other stimuli, i.e. type A (170 units), type B (42 units) and type C (60 units). Type A uni...

journal_title：Brain research

authors： Inoue T

更新日期：1980-03-17 00:00:00

abstract：:Accumulating evidence indicates that extensive microglia activation-mediated local inflammation contributes to neuronal injury in cerebral ischemia. We have previously shown that 4-(2-butyl-6, 7-dichloro-2-cyclopentyl-indan-1-on-5-yl) oxobutyric acid (DCPIB), a potent volume-regulated anion channel (VRAC) inhibitor, s...

journal_title：Brain research

authors： Han Q,Liu S,Li Z,Hu F,Zhang Q,Zhou M,Chen J,Lei T,Zhang H

更新日期：2014-01-13 00:00:00

abstract：:Hemicholinium-3 (HCh-3) is a potent and specific inhibitor of the high-affinity choline transport process (HAChT) localized on cholinergic neurons. In this study, the specific binding of [3H]HCh-3 (120 Ci/mmol) was characterized in crude synaptic membranes prepared from rat brain. The binding of [3H]HCh-3 to forebrain...

journal_title：Brain research

authors： Sandberg K,Coyle JT

更新日期：1985-12-02 00:00:00

abstract：:Peroxisome proliferator-activated receptor gamma (PPAR-gamma) has been described to have a role in the modulation of various genes involved in Abeta homeostasis, inflammation, and energy metabolism, making it a candidate gene for risk of Alzheimer's disease (AD). A functional polymorphism in exon 2 of the PPAR-gamma g...

journal_title：Brain research

authors： Yao L,Li K,Zhang L,Yao S,Piao Z,Song L

更新日期：2009-09-29 00:00:00

abstract：:On the first day after hatching 106 domestic chicks were injected with (14-C)uracil and exposed to a yellow or a red rotating flashing light for 72 min. Shortly before they were killed and 115 min after injection they were given a choice between the two lights. Incorporation of the (14-C)uracil into 4 regions of the b...

journal_title：Brain research

authors： Bateson PP,Horn G,Rose SP

更新日期：1975-02-07 00:00:00

abstract：:Fluorescence immunohistochemistry was performed to characterize the distribution and phenotype of GLUT8-positive neurons in rat brain and to compare the cellular distribution of GLUT8 with GLUT3 in the hippocampus. Based upon the absence of co-localization with the non-neuronal markers GFAP (astroglial) and OX42 (micr...

journal_title：Brain research

authors： Reagan LP,Rosell DR,Alves SE,Hoskin EK,McCall AL,Charron MJ,McEwen BS

更新日期：2002-04-05 00:00:00

abstract：:The ultrastructure of the dorsal column nucleus (DCN) has been investigated at the level of the obex region in normal and experimental toads. Large 'isolated' neurons (greater than 20 micrometer) and clusters of small neurons (less than 20 micrometer) have been identified in this region. Synaptic profiles have been cl...

journal_title：Brain research

authors： Corvaja N,Pellegrini M,Buisseret-Delmas C

更新日期：1978-03-10 00:00:00

abstract：:Administration of non-competitive N-methyl-D-aspartate (NMDA) receptor antagonists (e.g. phencyclidine, MK-801) has been shown to elicit behavioral abnormalities related to symptoms of schizophrenia, such as spontaneous locomotor activity and impaired sensorimotor gating, as represented by deficits of prepulse inhibit...

journal_title：Brain research

authors： Uehara T,Sumiyoshi T,Seo T,Matsuoka T,Itoh H,Suzuki M,Kurachi M

更新日期：2010-09-17 00:00:00

abstract：:Brain-derived neurotrophic factor (BDNF) expression changes in the dorsal root ganglion (DRG) and spinal cord in some pain models. Recently, rat BDNF transcripts containing novel 5' untranslated exons were identified and characterized, and a new numbering system for rat BDNF exons was introduced. We examined the expre...

journal_title：Brain research

authors： Kobayashi H,Yokoyama M,Matsuoka Y,Omori M,Itano Y,Kaku R,Morita K,Ichikawa H

更新日期：2008-04-24 00:00:00

abstract：:Nuclear factor one X (NFIX) has been shown to play a pivotal role during the development of many regions of the brain, including the neocortex, the hippocampus and the cerebellum. Mechanistically, NFIX has been shown to promote neural stem cell differentiation through the activation of astrocyte-specific genes and via...

journal_title：Brain research

authors： Vidovic D,Harris L,Harvey TJ,Evelyn Heng YH,Smith AG,Osinski J,Hughes J,Thomas P,Gronostajski RM,Bailey TL,Piper M

更新日期：2015-08-07 00:00:00

abstract：:We have investigated the influence of central noradrenergic and dopaminergic systems on the susceptibility of rats to seizures in the kainic acid (KA)-model of epilepsy. In the dose range of 0.75 to 10 mg/kg s.c., KA dose-dependently induced characteristic behavioural changes. Partial depletion of noradrenaline (NA) a...

journal_title：Brain research

authors： Baran H,Hörtnagl H,Hornykiewicz O

更新日期：1989-08-28 00:00:00

abstract：:The effects of the epileptogenic agent, penicillin, on excitatory and inhibitory postsynaptic potentials (EPSPs and IPSPs) were studied in the hippocampal in vitro slice preparation. The actions of penicillin were compared to those of bicuculline, an antagonist of gamma-aminobutyric acid. Neither substance enhanced mo...

journal_title：Brain research

authors： Schwartzkroin PA,Prince DA

更新日期：1980-02-03 00:00:00

abstract：:It has recently been shown that the lobules 9 and 10 of the cerebellum contain high densities of dopamine D3 receptors (and almost no D2 receptors [Bouthenet, M.L., Souil, E., Martres, M.P., Sokoloff, P., Giros, B. and Schwartz, J.C., Brain Res., 564 (1991) 203-219; Sokoloff, P., Giros, B., Martres, M.P., Bouthenet, M...

journal_title：Brain research

authors： Barik S,de Beaurepaire R

更新日期：1996-10-21 00:00:00

abstract：:Parkin Co-Regulated Gene (PACRG) is a novel gene that is oriented in a head-to-head array with parkin, and expression of the two genes is regulated by a shared bi-directional promoter. Mutations in parkin are the most common cause of early-onset autosomal recessive Parkinson's disease, however the function of PACRG an...

journal_title：Brain research

authors： Brody KM,Taylor JM,Wilson GR,Delatycki MB,Lockhart PJ

更新日期：2008-03-27 00:00:00

abstract：:A review of the available literature reveals that proliferation of ependyma occurs during embryological and early postnatal periods of development. Turnover, however, declines significantly during postnatal life and only low levels of residual activity persist into adulthood under normal conditions. In some regions of...

journal_title：Brain research

authors： Bruni JE,Del Bigio MR,Clattenburg RE

更新日期：1985-04-01 00:00:00

abstract：:The time courses for development of neuronal and behavioral tolerance to diazepam (DZ) were estimated in rats continuously exposed to low levels of DZ for 3, 7, 14 or 21 days. Microiontophoretic sensitivity of dorsal raphe neurons to gamma-aminobutyric acid (GABA) was initially facilitated after short-term exposure to...

journal_title：Brain research

authors： Gonsalves SF,Gallager DW

更新日期：1987-03-03 00:00:00

abstract：:EEG recordings of hippocampal theta activity and neocortical activity were correlated with direct observations and photographic recordings of the behaviour of unrestrained cats. The behaviour studied included (1) both spontaneous and induced changes in level of arousal (sleep-wakefulness), (2) different types of orien...

journal_title：Brain research

authors： Kemp IR,Kaada BR

更新日期：1975-09-23 00:00:00

abstract：:These experiments examined the effects, on retention, of posttraining intra-amygdala administration of norepinephrine (NE), and propranolol. Rats were trained on a one-trial step-through inhibitory avoidance task and tested for retention 24 h later. Injections were administered bilaterally (1.0 microliter/injection) t...

journal_title：Brain research

authors： Liang KC,Juler RG,McGaugh JL

更新日期：1986-03-12 00:00:00

abstract：:[1-14C]Octanoate (OCTO) is rapidly extracted from blood and metabolized by brain. Up to 6 min following an intravenous pulse injection the autoradiographic pattern of brain labeling reflects differences in blood flow and energy metabolism. When animals are given OCTO during visual or somatosensory stimulation the auto...

journal_title：Brain research

authors： Rowley H,Collins RC

更新日期：1985-06-03 00:00:00

abstract：:The immunocytochemical localization of the enzyme choline acetyltransferase (ChAT) was examined in the guinea pig organ of Corti to determine if both lateral and medial systems of efferents would show immunoreactive labeling for this specific enzyme marker of cholinergic neurons. Cochleae were also examined after lesi...

journal_title：Brain research

authors： Altschuler RA,Kachar B,Rubio JA,Parakkal MH,Fex J

更新日期：1985-07-08 00:00:00

abstract：:Choline molecules are needed for the synthesis of acetylcholine and phospholipids in the mammalian brain. An enzymatic activity capable of forming lecithin (phosphatidylcholine) from the step-by-step methylation of phosphatidylethanolamine is identified in the bovine brain. This enzyme(s), phosphatidylethanolamine-N-m...

journal_title：Brain research

authors： Blusztajn JK,Zeisel SH,Wurtman RJ

更新日期：1979-12-28 00:00:00

abstract：:In serum-free monolayer cultures of early postnatal weaver (wv/wv) cerebellum granule neurons show decreased attachment, survival and neurite outgrowth when compared to wild-type (+/+) littermate cultures. wv/wv Astrocytes display a more epithelioid morphology and altered proliferation. However, both morphology and pr...

journal_title：Brain research

authors： Fischer G,Keilhauer G,Schachner M

更新日期：1986-08-01 00:00:00

abstract：:The pedunculopontine tegmental nucleus (PPT) has been implicated in the generation and/or maintenance of both active sleep (AS) and wakefulness (W). GABAergic neurons are present within this nucleus and recent studies have shown that these neurons are active during AS. In order to examine the role of mesopontine GABAe...

journal_title：Brain research

authors： Torterolo P,Morales FR,Chase MH

更新日期：2002-07-19 00:00:00

abstract：:Entopeduncular nucleus (EPN) cells which project to thalamic and non-thalamic sites were identified by antidromic discharge. Each population of cells, projecting to the ventral anterior nucleus of the thalamus (VA), centrum medianum (CM), the lateral habenula (LHB), and the pedunculopontine nucleus (PP), was distribut...

journal_title：Brain research

authors： Larsen KD,Sutin J

更新日期：1978-11-17 00:00:00

abstract：:Retinae taken from embryonic mice were transplanted to the brain of newborn rats. One eye was removed from the recipients at this time to promote innervation of host visual centers. After 4-6 weeks the optic nerve of the remaining eye was transected to eliminate all visual afferents of host origin and 4-6 days later t...

journal_title：Brain research

authors： Klassen H,Lund RD

更新日期：1990-11-19 00:00:00