Escapable and inescapable stress differentially and selectively alter extracellular levels of 5-HT in the ventral hippocampus and dorsal periaqueductal gray of the rat.

abstract：:Gonadotrophin-releasing hormone (GnRH) neurons do not express the leptin receptor (OB-R) in the medial preoptic area (MPOA) and the medial basal hypothalamus (MBH). We assessed whether the effect of leptin on the secretion of luteinizing hormone (LH), follicle stimulating hormone (FSH) and prolactin (PRL) in proestrus...

journal_title：Brain research

authors： Del Bianco-Borges B,Franci CR

更新日期：2015-04-16 00:00:00

abstract：:Delta-9-tetrahydrocannabinol (Delta(9)-THC), the main psychoactive component of marijuana, is known to dysregulate various immune responses. Cannabinoid (CB)-1 and -2 receptors are expressed mainly on cells of the central nervous system (CNS) and the immune system. The CNS is the primary target of cannabinoids and ast...

journal_title：Brain research

authors： Bindukumar B,Mahajan SD,Reynolds JL,Hu Z,Sykes DE,Aalinkeel R,Schwartz SA

更新日期：2008-01-29 00:00:00

abstract：:The activity of 294 single units was recorded from the dorsolateral prefrontal cortex of monkeys performing two visual discrimination tasks with delayed response. One task, delayed matching-to-sample (DMS), required memory of a colored cue for later (18 s) matching and choice of color; the cue did not connote the loca...

journal_title：Brain research

authors： Quintana J,Yajeya J,Fuster JM

更新日期：1988-12-06 00:00:00

abstract：:Transient global ischemia induces selective, delayed neuronal death of pyramidal neurons in the hippocampal CA1. Whereas long term treatment of middle-aged female rats with estradiol at physiological doses ameliorates neuronal death, the signaling pathways that mediate the neuroprotection are, as yet, unknown. Protein...

journal_title：Brain research

authors： De Butte-Smith M,Zukin RS,Etgen AM

更新日期：2012-08-30 00:00:00

abstract：UNLABELLED:Mating in rabbits lasts only 3-5s but profoundly changes the female׳s physiology and behavior (e.g., inhibition of scent-marking and ambulation, changes in EEG, and release of GnRH). The behavioral responsiveness to copulation is reduced in lactating rabbits, relative to estrous does, but is enhanced after s...

journal_title：Brain research

authors： González-Mariscal G,García Dalmán C,Jiménez A

更新日期：2015-05-22 00:00:00

abstract：:The response of trunk neural crest cells taken from precise levels of the neural axis and cultured together with adjacent somites to Brain-derived neurotrophic factor (BDNF), was examined in cultures grown in a chemically defined medium. In control cultures, the number of neural crest-derived neurons expressing the HN...

journal_title：Brain research

authors： Kalcheim C,Gendreau M

更新日期：1988-06-01 00:00:00

abstract：:Histamine is one of the neurotransmitters suppressing appetite, but the interactions of histaminergic neurons with other neurons in satiety centers have not been clarified. Noradrenaline in the para-ventricular nucleus (PVN) has been shown to stimulate feeding. This study was designed to determine whether histamine mo...

journal_title：Brain research

authors： Kurose Y,Terashima Y

更新日期：1999-05-15 00:00:00

abstract：:The human neostriatum was found to contain large neurons (maximum diameter: 30-40 microns) that stain intensely for acetylcholinesterase (AChE). These neurons are few in number, representing less than 5% of the total striatal neuronal population, and appear uniformly scattered throughout the caudate nucleus and putame...

journal_title：Brain research

authors： Parent A,Csonka C,Etienne P

更新日期：1984-01-16 00:00:00

abstract：:Epileptic discharge patterns in an acute experimental model of epilepsy were analyzed. Epileptic foci were induced by epicortical application of penicillin on the rat motor cortex in vivo. Patterns with regular 1/s discharges, patterns with irregular discharges of about 0.5/s as well as compound patterns comprising di...

journal_title：Brain research

authors： Dorn T,Witte OW

更新日期：1993-07-09 00:00:00

abstract：:Echo-planar magnetic resonance imaging (EP-MRI), which is novel variant of MRI, is thought to have antidepressant properties in humans and animal models. Using the forced swimming test (FST), we investigated which monoaminergic system in mice is affected by EP-MRI. The short- and long-term effects of EP-MRI on immobil...

journal_title：Brain research

authors： Aksoz E,Aksoz T,Bilge SS,Ilkaya F,Celik S,Diren HB

更新日期：2008-10-21 00:00:00

abstract：:We previously reported that the level of Ca2+/calmodulin-dependent protein kinase II (CaM kinase II) alpha and beta proteins increases with postnatal age. In the present study, we investigated the developmental changes in whole protein substrates of CaM kinase II as compared with those of cAMP-dependent protein kinase...

journal_title：Brain research

authors： Sugiura H,Yamauchi T

更新日期：1994-10-03 00:00:00

abstract：:The nigrostriatal projection was studied with a retrograde tracing method (Evans blue, EB) combined with a technique for dopamine histofluorescence. The study, realized in control rats and in animals with 6-hydroxydopamine-induced lesions of the dopaminergic pathway, yielded the following results. (1) In 3 control rat...

journal_title：Brain research

authors： Guyenet PG,Crane JK

更新日期：1981-06-01 00:00:00

abstract：:Bcl-2 has been hypothesized to regulate many cellular functions in addition to its well-characterized role in the prevention of programmed cell death. To understand the role of Bcl-2 in regulating cell morphology and to explore the mechanism of this effect, we examined the effects of Bcl-2 overexpression on the morpho...

journal_title：Brain research

authors： Mi Z,Mirnics ZK,Schor NF

更新日期：2006-09-27 00:00:00

abstract：:The suprachiasmatic nucleus (SCN) of the anterior hypothalamus is implicated in the temporal organization of circadian rhythms in a variety of physiological, endocrine and behavioral processes. There is a great deal of evidence indicating that aging is characterized by a progressive deterioration of circadian timekeep...

journal_title：Brain research

authors： Hofman MA,Swaab DF

更新日期：1994-07-18 00:00:00

abstract：:Acute and repeated exposure to cocaine induces long-lasting alterations in neural networks that underlie compulsive drug seeking and taking. Cocaine exposure triggers complex adaptations in the brain that are mediated by dynamic patterns of gene expression that are translated into enduring changes. Recently, epigeneti...

journal_title：Brain research

authors： Sadri-Vakili G

更新日期：2015-12-02 00:00:00

abstract：:The two neurosteroids 3alpha-hydroxy-5alpha-pregnane-20-one (allopregnanolone; AlloP) and pregnenolone sulfate (PregS) affect neuronal GABA(A) receptors differently. While AlloP mainly potentiates the currents through GABA(A) receptors, PregS reduces such currents. The present study aimed at clarifying the interaction...

journal_title：Brain research

authors： Haage D,Bäckström T,Johansson S

更新日期：2005-02-01 00:00:00

abstract：:A procedure is described for identifying the motor neurons innervating individual cockroach muscles by use of the retrograde transport of extracellularly injected horseradish peroxidase and the staining of cells in whole mount preparations. A modification of this procedure using wheat germ agglutinin covalently conjug...

journal_title：Brain research

authors： Denburg JL

更新日期：1982-09-23 00:00:00

abstract：:Prolidase deficiency is characterized by chronic ulcerative dermatitis, mental retardation, and frequent infections. In the present study we examined the characteristics of rat brain prolidase isoenzymes. Prolidase isoenzymes (PD I and PD II) were isolated from the rat brain using DEAE cellulose column chromatography....

journal_title：Brain research

authors： Chi H,Lu J,Liu G,Tong J,Nakayama K,Yamashita K,Kitaoka N,Kodama H

更新日期：2009-12-15 00:00:00

abstract：:Morphological, electrophysiological and behavioral studies were carried out in cats after unilateral kainic acid injection in the substantia nigra. A forced contralateral head turning and compulsive circling was observed after surgery. Fifteen days after, when asymmetry disappeared, apomorphine induced an ipsilateral ...

journal_title：Brain research

authors： Motles E,Saavedra H,Infante C,Leiva J,Gonzalez M

更新日期：1987-03-03 00:00:00

abstract：:Noise analysis was used to estimate the single-channel conductance and number of channels responsible for the mechanically-activated current in the sensory neurons of a spider mechanoreceptor organ. External slits of the VS-3 slit-sense organ in the patellar cuticle of Cupiennius salei were moved with a piezoelectric ...

journal_title：Brain research

authors： Höger U,French AS

更新日期：1999-05-01 00:00:00

abstract：:Immobilization of frogs for 1 h induces analgesia which is blocked but not reversed by low doses of naloxone. After 9 days of daily immobilization for 1 h, the treatment fails to cause analgesia thus indicating that tolerance has developed. Animals tolerant to immobilization-induced analgesia do not show cross-toleran...

journal_title：Brain research

authors： Pezalla PD,Dicig M

更新日期：1984-04-02 00:00:00

abstract：:Changes in synaptic efficacy, including long-term potentiation (LTP) and long-term depression (LTD), provide mechanisms for experience-induced plasticity of cortical and subcortical circuits. LTP is readily induced under drastically different experimental conditions (e.g., in vitro and in vivo). However, few studies h...

journal_title：Brain research

authors： Hager AM,Dringenberg HC

更新日期：2010-03-08 00:00:00

abstract：:1-(p-Bromobenzoyl)-piperazine-2,3-dicarboxylic acid (pBB-PzDA; 0.03-5 mM), an excitatory amino acid antagonist, was perfused through the guinea pig cochlea while monitoring various cochlear potentials. pBB-PzDA (1-5 mM) reversibly suppressed the amplitude of the compound action potential of the auditory nerve (CAP) an...

journal_title：Brain research

authors： Puel JL,Bobbin RP,Fallon M

更新日期：1989-05-15 00:00:00

abstract：:CNS inflammation is a sequela of a variety of neuropathological conditions resulting in extensive tissue loss. Inflammation is mediated primarily by phagocytic cells, but the mechanisms of CNS tissue destruction are not fully understood. Hypochlorous acid (HOCl) is by far the most abundant agent generated by phagocyti...

journal_title：Brain research

authors： Krasowska A,Konat GW

更新日期：2004-02-06 00:00:00

abstract：:Intracerebroventricular (i.c.v.) administration of corticotropin-releasing factor (CRF) biphasically affects performance in tests of learning and memory. In the present study, we used CRF, urocortin (Ucn), a recently cloned CRF homologue, and CRF receptor antagonists, to determine which CRF receptor subtype(s) mediate...

journal_title：Brain research

authors： Zorrilla EP,Schulteis G,Ormsby A,Klaassen A,Ling N,McCarthy JR,Koob GF,De Souza EB

更新日期：2002-10-18 00:00:00

abstract：:Histopathological analyses of brains of rats receiving a single 0.9 LD50 injection of soman, a potent anticholinesterase neurotoxin, revealed massive widespread lesions in the cerebral cortex and thalamus 4 weeks post-injection. Such lesions were not evidenced in rats receiving diazepam (2.2 mg/kg, i.m.) 10 min prior ...

journal_title：Brain research

authors： Martin LJ,Doebler JA,Shih TM,Anthony A

更新日期：1985-01-28 00:00:00

abstract：:The so-called on- and off-cells of the rostral ventromedial medulla (RVM) send their axons to the spinal dorsal horn. Activation of on-cells precedes and coincides with a facilitation, and activation of off-cells coincides with an inhibition, of withdrawal reflexes elicited by noxious agents. Considerable evidence sup...

journal_title：Brain research

authors： Salas R,Ramirez K,Tortorici V,Vanegas H,Vazquez E

更新日期：2018-05-01 00:00:00

abstract：:During the last few years, recombinant viral vectors derived from adenovirus (Ad), adeno-associated virus (AAV) or lentivirus (LV) have been developed into highly effective vehicles for gene transfer to the adult central nervous system. In recent experiments, in the rat model of Parkinson's disease, all three vector s...

journal_title：Brain research

authors： Björklund A,Kirik D,Rosenblad C,Georgievska B,Lundberg C,Mandel RJ

更新日期：2000-12-15 00:00:00

abstract：:Depending on experimental conditions, chronic cocaine exposure can induce an increase in binding to the dopamine transporter (DAT). One possible mechanism for the cocaine-induced-upregulation in DAT binding sites is through stimulation of presynaptic D2 receptors by excess synaptic dopamine. To test this hypothesis, t...

journal_title：Brain research

authors： Little KY,Gorebig J,Carroll FI,Mapili J,Meador-Woodruff JH

更新日期：1996-12-02 00:00:00

abstract：:The postnasal development of the Na-independent [3H]glutamate binding sites, which exhibit some characteristics of postsynaptic glutamate receptors, has been studied in rat hippocampal membranes. The amount of binding sites (expressed in pmol/hippocampus) represents 4% of the adult level at postnatal day (PND) 4, incr...

journal_title：Brain research

authors： Baudry M,Arst D,Oliver M,Lynch G

更新日期：1981-01-01 00:00:00