Grafting of midbrain neurons into the hippocampus restores serotonergic modulation of hippocampal activity in the rat.

abstract：:GABA-A receptors mediate both phasic synaptic inhibition and more recently appreciated tonic currents in the vertebrate central nervous system. We addressed discrepancies in the literature regarding the pharmacology of tonic currents by examining tonic currents in a controlled environment of dissociated, solitary glut...

journal_title：Brain research

authors： Eisenman LN,Kress G,Zorumski CF,Mennerick S

更新日期：2006-11-06 00:00:00

abstract：:The levels of N-acetyl-aspartate (NAA) and N-acetyl-aspartyl-glutamate (NAAG) were measured in several regions and in whole brain of rats from 15 days of gestation (DG) to adulthood by means of an isocratic HPLC method. The levels of NAAG in whole brain increased 3-fold between 15 DG and birth, which was 90% of the ad...

journal_title：Brain research

authors： Koller KJ,Coyle JT

更新日期：1984-07-01 00:00:00

abstract：:During embryogenesis, transient expression of nestin in proliferating neuroepithelial stem cells signals the commitment of progenitor cells to differentiate. Although adult mammalian brain contains very little nestin, significant upregulation of nestin has been reported following cerebral injury, leading to speculatio...

journal_title：Brain research

authors： Douen AG,Dong L,Vanance S,Munger R,Hogan MJ,Thompson CS,Hakim AM

更新日期：2004-05-22 00:00:00

abstract：:Maternal infection during pregnancy is associated with an increased risk of neurodevelopmental injury. Our aim was to investigate whether prenatal immune challenge could alter susceptibility to seizure-induced brain injury in adulthood. Pregnant Wistar rats were injected intraperitoneally with lipopolysaccharide (LPS)...

journal_title：Brain research

authors： Yin P,Liu J,Li Z,Wang YY,Qiao NN,Huang SY,Li BM,Sun RP

更新日期：2013-06-26 00:00:00

abstract：:The calcium channel antagonists omega-agatoxin IIIA (omega-Aga-IIIA) and omega-conotoxin GVIA (omega-CgTx) were radioiodinated and used to locate binding sites in the rat brain by receptor autoradiography. While patterns of regional binding to sagittal sections of rat brain were generally similar for the 2 toxins, not...

journal_title：Brain research

authors： McIntosh JM,Adams ME,Olivera BM,Filloux F

更新日期：1992-10-23 00:00:00

abstract：:Two high molecular weight surface glycoproteins of cerebellar cells which are selectively labeled by lactoperoxidase-catalyzed iodination of monolayer cultures from the developing mouse cerebellum, have been identified and partially characterised. Both molecules, called peak 2 and peak 3 proteins, were the major glyco...

journal_title：Brain research

authors： Goridis C,Hirsch M,Dossetto M,Baechler E

更新日期：1980-01-27 00:00:00

abstract：:Tacrolimus (FK506), a potent immunosuppressive drug, is effective in attenuating brain infarction after cerebral ischemia. However, there has been no report characterizing the neuroprotective action and therapeutic time window of tacrolimus systematically using different types of stroke models and extended observation...

journal_title：Brain research

authors： Furuichi Y,Katsuta K,Maeda M,Ueyama N,Moriguchi A,Matsuoka N,Goto T,Yanagihara T

更新日期：2003-03-07 00:00:00

abstract：:Kindling of the ventral tegmental area (VTA), a major source of the mesolimbic dopamine pathway, was examined in rats. We applied two quantitative measurements of dopamine sensitivity before and 2 weeks after VTA kindling (20 times electrical stimulations (100 microA at 1 min intervals) delivered once per day for 14 c...

journal_title：Brain research

authors： Watanabe T,Morimoto K,Nakamura M,Hirao T,Ninomiya T,Ando N,Suwaki H

更新日期：2004-04-02 00:00:00

abstract：:Alzheimer's disease (AD) is one of the most common forms of dementia with still unknown pathogenesis. Several cytokines and chemokines are involved in the pathogenesis of AD. Among the chemokines, the CXCR4/CXCL12 complex has been shown to play an important role in the pathogenetic development of AD. We investigated t...

journal_title：Brain research

authors： Sanfilippo C,Castrogiovanni P,Imbesi R,Nunnari G,Di Rosa M

更新日期：2020-12-15 00:00:00

abstract：:The aim of the present study was to determine differences in cortical processing of consonant-vowel syllables and acoustically matched non-speech sounds, as well as novel human and nonhuman sounds. Event-related potentials (ERPs) were recorded to vowel, vowel duration, consonant, syllable intensity, and frequency chan...

journal_title：Brain research

authors： Sorokin A,Alku P,Kujala T

更新日期：2010-04-23 00:00:00

abstract：:The two primary categories of stroke, ischemic and hemorrhagic, both have fundamentally different mechanisms and thus different treatment options. These two stroke categories were applied to rat models to identify potential biomarkers that can distinguish between them. Ischemic stroke was induced by middle cerebral ar...

journal_title：Brain research

authors： Ren C,Zoltewicz S,Guingab-Cagmat J,Anagli J,Gao M,Hafeez A,Li N,Cao J,Geng X,Kobeissy F,Mondello S,Larner SF,Hayes RL,Ji X,Ding Y

更新日期：2013-12-02 00:00:00

abstract：:This study investigated the effects of N6-cyclopentyladenosine (CPA), a potent and selective adenosine A1 receptor (A1R) agonist in normal and nerve-injured rats and mechanisms of its action by behavioral tests and electrophysiological technique. The results showed: (1) In normal rats, intraperitoneal administration o...

journal_title：Brain research

authors： Gong QJ,Li YY,Xin WJ,Wei XH,Cui Y,Wang J,Liu Y,Liu CC,Li YY,Liu XG

更新日期：2010-11-18 00:00:00

abstract：:Due to the structural similarity to N-methyl-4-phenyl pyridinium (MPP(+)), paraquat might induce dopaminergic toxicity in the brain. However, its blood--brain barrier (BBB) penetration has not been well documented. We studied the manner of BBB penetration and neural cell uptake of paraquat using a brain microdialysis ...

journal_title：Brain research

authors： Shimizu K,Ohtaki K,Matsubara K,Aoyama K,Uezono T,Saito O,Suno M,Ogawa K,Hayase N,Kimura K,Shiono H

更新日期：2001-07-06 00:00:00

abstract：:Ginseng is one of most extensively used traditional oriental medicines worldwide with beneficial efficacy on cognitive function disorders. Pharmacological researches on its active ingredient--ginsenoside Rg1 revealed that it can improve learning and memory potentially via modulating neurotransmission in the central ne...

journal_title：Brain research

authors： Liu ZJ,Zhao M,Zhang Y,Xue JF,Chen NH

更新日期：2010-05-28 00:00:00

abstract：:Using site-specific antibodies, we assessed the effect of aggregation of various length forms of A beta on the immunoreactive profile of the peptides. All of the antibodies tested reacted with monomeric/dimeric forms of A beta 1-42 and its further aggregates. However, antibodies directed against the 1-24 region of A b...

journal_title：Brain research

authors： Kametani F,Tanaka K,Tokuda T,Allsop D

更新日期：1995-12-12 00:00:00

abstract：:Interactive-activation models posit that visual word recognition involves co-activation of orthographic neighbors (e.g., note, node) and competition among them via lateral inhibitory connections. Behavioral evidence of this lexical competition comes from masked priming paradigms, in which target words elicit slower re...

journal_title：Brain research

authors： Meade G,Grainger J,Midgley KJ,Emmorey K,Holcomb PJ

更新日期：2018-04-15 00:00:00

abstract：:Recordings were made from single neurons in the rat's central nucleus of the inferior colliculus (ICc). Binaural responses were studied when dichotic tone bursts with various interaural-level differences were presented simultaneously or with a contralateral delay. These dichotic tone bursts allowed us to probe tempora...

journal_title：Brain research

authors： Zhang H,Kelly JB

更新日期：2009-12-15 00:00:00

abstract：:We developed a new model of embolic cerebral ischemia in the rat which provides a reproducible and predictable infarct volume within the territory supplied by the middle cerebral artery (MCA). The MCA was occluded by an embolus in Wistar rats (n = 71). An additional three non-embolized rats were used as a control. Cer...

journal_title：Brain research

authors： Zhang RL,Chopp M,Zhang ZG,Jiang Q,Ewing JR

更新日期：1997-08-22 00:00:00

abstract：:Involvement of N-methyl-D-aspartate (NMDA) receptor complex and 5-hydroxytryptamine3 (5-HT3) receptors in state-dependent learning (SDL) induced by ethanol (EtOH) was investigated in the step-through passive avoidance task in rats. Pre-training injections of EtOH or MK-801 reduced step-through latency in the test sess...

journal_title：Brain research

authors： Nakagawa Y,Iwasaki T

更新日期：1996-01-15 00:00:00

abstract：:Endothelin (ET), a potent vasoconstrictor peptide, is believed to have central sites of action and potential neurohormonal effects relating to body fluid homeostasis and blood-pressure regulation. Systemic endothelin binds to receptors at circumventricular organs and has been shown to increase plasma concentrations of...

journal_title：Brain research

authors： Wall KM,Nasr M,Ferguson AV

更新日期：1992-01-20 00:00:00

abstract：:Fifty-three cell pairs in the somatosensory cerebral cortex were examined in pentobarbital-anesthetized cats for evidence of short latency interactions. Many neuronal pairs separated by distances of 150 to 500 micron were observed to have temporal dependencies. In a subset of 19 pairs where the surrounding multiunit a...

journal_title：Brain research

authors： Metherate R,Dykes RW

更新日期：1985-08-19 00:00:00

abstract：:Different groups of rats received three injections of either D-amphetamine (2.5 micrograms/0.5 microliters/side) or saline into the ventral tegmental area (VTA), one injection every third day. Two weeks following the last injection, dopamine (DA) neurotransmission in the nucleus accumbens (N. Acc.) was assessed with i...

journal_title：Brain research

authors： Vezina P

更新日期：1993-03-12 00:00:00

abstract：:Recent studies suggest that both sex and cerebral hemisphere influence brain mechanisms associated with emotional memory. Here we used evoked potentials to examine the influence of sex and hemisphere on brain responses to emotional stimuli. Given that the P300 component of the event-related brain potential (ERP) is co...

journal_title：Brain research

authors： Gasbarri A,Arnone B,Pompili A,Pacitti F,Pacitti C,Cahill L

更新日期：2007-03-23 00:00:00

abstract：:The possibility that the motor cortex receives peripheral input directly from the thalamus was examined using the evoked potential method and the following results were obtained. Potentials in the motor cortex evoked by stimulation of superficial radial (SR) or group II deep radial (DR) nerve were neither abolished no...

journal_title：Brain research

authors： Asanuma H,Larsen KD,Zarzecki P

更新日期：1979-08-24 00:00:00

abstract：:In albino rats the deep layers of the superior colliculus were stimulated, and climbing fiber responses of Purkinje cells were explored in the medial region of the lobulus simplex. They were identified in a strip (ca. 0.7-1.0 mm wide) in the most medial region of folium b. In the tectorecipient zone of the medial acce...

journal_title：Brain research

authors： Akaike T

更新日期：1987-08-11 00:00:00

abstract：:We have examined the role of the octopamine-containing buccal OC interneuron in the fictive feeding rhythm generated by depolarizing a modulatory interneuron, SO, in the isolated central nervous system (CNS) of Lymnaea stagnalis. Before stimulating the SO, the initial fictive feeding rate was 2.0+/-0.37 bites/min (mea...

journal_title：Brain research

authors： Elliott CJ,Vehovszky A

更新日期：2000-12-22 00:00:00

abstract：:Superfusion of the hepatic portal vein with hypertonic saline solutions increases the electrical activity of the hypothalamo-neurohypophysial tract. Bilateral cervical vagotomy had no effect on this response in all rats studied. Section of the hepatic branch of the vagus abolished the hypothalamic response in only two...

journal_title：Brain research

authors： Vallet PG,Baertschi AJ

更新日期：1982-05-06 00:00:00

abstract：:Rats received 1-stage bilateral and sequential unilateral (serial) lesions of the posterior hypothalamus and were tested for the ability to regulate body temperature after a lengthy recovery period. The groups with lesion differed from the sham-operated groups in the cold, although not under ambient or warm conditions...

journal_title：Brain research

authors： Bell J,Gruenthal M,Finger S,Mangold R

更新日期：1981-08-31 00:00:00

abstract：:Postsynaptic potentials were evoked in neostriatal neurons by stimulation of the ipsilateral and contralateral medial agranular frontal cortical field (AGm) in the rat. This cortical region is known to project bilaterally to the dorsal lateral head of the caudate-putamen of rats. Ipsilateral stimulation of AGm should ...

journal_title：Brain research

authors： Wilson CJ

更新日期：1986-03-05 00:00:00

abstract：:Extracellular recording was used to investigate spontaneously active neurons in all four major nuclei of the rat vestibular nuclear complex (VNC) in brainstem slices. The density of spontaneously active neurons was highest in the medial vestibular nucleus (MVN), slightly lower in the superior (SuVN) and spinal (SpVN) ...

journal_title：Brain research

authors： Sun Y,Waller HJ,Godfrey DA,Rubin AM

更新日期：2002-04-26 00:00:00