The organization of the efferent projections and striatal afferents of the entopeduncular nucleus and adjacent areas in the rat.

abstract：:The contribution of the pedunculopontine nucleus to exploratory locomotion was investigated in rats. Locomotor activity recorded in a standard open-field apparatus was increased more than two-fold when wooden panels were inserted. This novelty-elicited locomotion was reduced significantly when procaine was injected bi...

journal_title：Brain research

authors： Mogenson GJ,Wu M,Tsai CT

更新日期：1989-04-24 00:00:00

abstract：:The window method of radiolabeled protein analysis was used to study the transport kinetics of axonally transported cytomatrix proteins as they move through segments of mouse optic axons. Three slow component b (SCb) proteins--actin, a 30 kDa protein, and clathrin--were radiolabeled in the eye and were followed for up...

journal_title：Brain research

authors： Paggi P,Lasek RJ,Katz MJ

更新日期：1990-05-28 00:00:00

abstract：:The protective activity of trimetazidine (TMZ) against cochlear neurotoxicity induced by intraperitoneal and intracochlear administration of kainic acid (KA) has been analyzed. The amplitude of the CAP N1 wave was significantly higher in KA rats pretreated with TMZ, independently of the administration route, than in t...

journal_title：Brain research

authors： Gil-Loyzaga P,Hernández E,Carricondo F,Simón F,Poch-Broto J

更新日期：1999-04-24 00:00:00

abstract：:Recent studies, which have shown an increase of plasma vasopressin (VP) in experimental motion sickness and the efficacy of VP antagonists for motion sickness, suggest an important role of VP in the development of vestibulo-autonomic responses. We have recently found evidence of the co-existence of vasopressinergic ne...

journal_title：Brain research

authors： Horii A,Koike K,Uno A,Uno Y,Kubo T

更新日期：2001-09-28 00:00:00

abstract：:Malignant glioma cells maintain an elevated intracellular pH (pH(i)) within hypoxic-ischemic tumor microenvironments through persistent activation of sodium-proton transport (McLean et al., 2000). Amiloride has been reported to selectively kill human malignant glioma cell lines but not primary astrocytes (Hegde et al....

journal_title：Brain research

authors： Harley W,Floyd C,Dunn T,Zhang XD,Chen TY,Hegde M,Palandoken H,Nantz MH,Leon L,Carraway KL 3rd,Lyeth B,Gorin FA

更新日期：2010-12-02 00:00:00

abstract：:The purpose of this investigation was to test the hypothesis that the discriminative stimulus properties of pentazocine are mediated through an interaction with dopamine receptors. Rats were trained to discriminate s.c. injections of pentazocine (3.0 mg/kg) from vehicle in a two-choice discrete trial avoidance paradig...

journal_title：Brain research

authors： Ukai M,Nakayama S,Hamada T,Kameyama T

更新日期：1989-09-04 00:00:00

abstract：:Electrical stimulation of the retina evokes at the optic tract level rhythmic bursts of activity whose temporal structure is predictable from the polarity of the stimulation and the receptive field type. The reaction of lateral geniculate units to this input was studied in fast and slow relay cells as well as in inter...

journal_title：Brain research

authors： Molotchnikoff S,Lachapelle P

更新日期：1978-08-18 00:00:00

abstract：:Identifiable giant neurons of Aplysia explored intracellularly behave differently at the offset of an intracellular electroshock (IES) or after a synaptic 'tetanization', according to their functional type: neurons of the stable type depolarize and fire at the offset of the IES, anodal or cathodal, thus eliciting an a...

journal_title：Brain research

authors： Chalazonitis N,Boisson M,Rome-Talbot D,Chagneux R

更新日期：1982-09-30 00:00:00

abstract：:The incidence of amyotrophic lateral sclerosis (ALS) is higher among men than women but rises in women after the menopause. Estrogens may play a protective role. Treatment with estrogens has been shown to be neuroprotective in models of several neurodegenerative diseases. We therefore determined the effect of ovariect...

journal_title：Brain research

authors： Groeneveld GJ,Van Muiswinkel FL,Sturkenboom JM,Wokke JH,Bär PR,Van den Berg LH

更新日期：2004-09-17 00:00:00

abstract：:The discriminative stimulus properties of ethanol are functionally regulated by ionotropic GABA(A) and NMDA receptors in specific limbic brain regions including the nucleus accumbens, amygdala, and hippocampus, as determined by microinjection studies. The purpose of the present work was to further investigate potentia...

journal_title：Brain research

authors： Besheer J,Schroeder JP,Stevenson RA,Hodge CW

更新日期：2008-09-26 00:00:00

abstract：:Alzheimer's disease (AD) classically presents with gray matter atrophy, as well as feature significant white matter abnormalities. Previous evidence indicates the overall burden of these pathological changes continues to advance as the disease progresses. The aim of this study was to investigate whether pathological a...

journal_title：Brain research

authors： Kitamura S,Kiuchi K,Taoka T,Hashimoto K,Ueda S,Yasuno F,Morikawa M,Kichikawa K,Kishimoto T

更新日期：2013-06-17 00:00:00

abstract：:Tetanic stimulation of fibers in the hippocampal slice preparation produces long-term potentiation (LTP) and also decreases the in vitro incorporation of phosphate into the alpha subunit of pyruvate dehydrogenase (alpha PDH). This paper describes 6 experiments that were undertaken to replicate this observation. Hippoc...

journal_title：Brain research

authors： Hoch DB,Dingledine RJ,Wilson JE

更新日期：1984-06-04 00:00:00

abstract：:Regeneration of crushed axons in rat dorsal spinal roots was measured to investigate the transganglionic influence of an additional peripheral axonal injury. The right sciatic nerve was cut at the hip and the left sciatic nerve was left intact. One week later, both fifth lumbar dorsal roots were crushed and subsequent...

journal_title：Brain research

authors： Richardson PM,Verge VM

更新日期：1987-05-19 00:00:00

abstract：:Pharmacological characteristics of native neuronal nicotinic acetylcholine receptor-mediated ion currents in mouse N1E-115 neuroblastoma cells have been investigated by superfusion of voltage clamped cells with known concentrations of the agonists acetylcholine, nicotine and cytisine, and the antagonists alpha-bungaro...

journal_title：Brain research

authors： Zwart R,Abraham D,Oortgiesen M,Vijverberg HP

更新日期：1994-08-22 00:00:00

abstract：:We have previously used organotypic cultures to study mechanisms regulating phenotypic expression of neurotransmitter characters in the brain. Our previous work indicated that nerve growth factor (NGF) specifically increased the activity of choline acetyltransferase (CAT) in striatal cholinergic interneurons. In the p...

journal_title：Brain research

authors： Martínez HJ,Dreyfus CF,Jonakait GM,Black IB

更新日期：1987-06-02 00:00:00

abstract：:Cytosolic phospholipase A2 (cPLA2) catalyzes the selective release of arachidonic acid from the sn-2 position of membrane phospholipids and has been suggested as an effector in the receptor-mediated release of arachidonic acid in signal transduction. The potential role of cPLA2 as an effector in muscarinic acetylcholi...

journal_title：Brain research

authors： Lautens LL,Chiou XG,Sharp JD,Young WS 3rd,Sprague DL,Ross LS,Felder CC

更新日期：1998-10-26 00:00:00

abstract：:Attack by a cat on a rat was elicited by electrical stimulation of the ventral parabrachial nucleus or the paralemniscal pontine reticular formation. The attack was quiet and it differed from similar behavior elicited at other sites in that the cat not only bit the rat but struck it with its paw. Horseradish peroxidas...

journal_title：Brain research

authors： Smith DA,Flynn JP

更新日期：1979-03-23 00:00:00

abstract：:Dravet syndrome (DS) is a genetic form of severe epilepsy often associated with mutation of the SCN1A gene encoding the voltage gated sodium channel Nav1.1. Typically refractive to conventional therapy, serotonin neurotransmission may be an innovative target for treatment. To further understand the role of serotonin i...

journal_title：Brain research

authors： Hatini PG,Commons KG

更新日期：2019-12-01 00:00:00

abstract：:This study evaluated the hypothesis that the dorsal motor nucleus (DMN) of the brainstem may mediate the ulcerogenic and acid-stimulatory effects of thyrotropin-releasing hormone (TRH) in rats. To accomplish this, intra-DMN microinjections of TRH (50 and 500 ng) were performed and their effects on acid secretion and g...

journal_title：Brain research

authors： Hernandez DE,Emerick SG

更新日期：1988-08-30 00:00:00

abstract：:Baclofen-sensitive GABAB receptor binding to various brain regions was compared in age-matched spontaneously hypertensive (SHR) and normotensive Wistar-Kyoto (WKY) rat. The specific [3H]baclofen binding was significantly higher in SHR cerebellum, hippocampus and nucleus tractus solitarii (NTS), but lower in medulla, w...

journal_title：Brain research

authors： Singh R,Ticku MK

更新日期：1985-12-09 00:00:00

abstract：:An immunoneutralization technique with specific antibodies was used to explore the role of endogenous neuropeptide Y (NPY) in the adrenocorticotropic hormone (ACTH) release after hypoglycemic stress in the dog. Dogs received injections of rabbit antihuman NPY gamma-globulin (anti-NPY) or normal gamma-globulin (NGG) in...

journal_title：Brain research

authors： Inui A,Inoue T,Nakajima M,Okita M,Sakatani N,Okimura Y,Chihara K,Baba S

更新日期：1990-03-05 00:00:00

abstract：:Attention-Deficit/Hyperactivity Disorder (ADHD) is associated with deficits in fluid reasoning, which may be related to self-regulation of cognition and behavior, and requires intact attention, working memory, and inhibition skills. No functional magnetic resonance imaging (fMRI) studies have directly examined fluid r...

journal_title：Brain research

authors： Tamm L,Juranek J

更新日期：2012-07-17 00:00:00

abstract：:The dorsolateral funiculus (DLF) spinal pathway has previously been identified as a major pathway involved in descending modulation of pain. While bilateral lesions of the DLF attenuated systemic morphine analgesia as measured by the tail-flick test, they failed to attenuate analgesia as measured by the formalin test....

journal_title：Brain research

authors： Ryan SM,Watkins LR,Mayer DJ,Maier SF

更新日期：1985-05-13 00:00:00

abstract：:Nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d) containing fibers and neurons within the hippocampal formation and entorhinal cortex of the new world monkey were determined using a direct histochemical procedure. Occasional intensely stained bipolar NADPH-d positive neurons were seen in the polymorphi...

journal_title：Brain research

authors： Mufson EJ,Brady DR,Carey RG

更新日期：1990-05-21 00:00:00

abstract：:The diurnal rhythm of neuropeptide Y (NPY)-like immunoreactivity was examined in 9 discrete hypothalamic sites of rats maintained on a 12:12 h light/dark cycle. Significant bimodal rhythms of NPY concentration were detected in the suprachiasmatic and arcuate nuclei, with significant peaks just prior to onset of the no...

journal_title：Brain research

authors： Jhanwar-Uniyal M,Beck B,Burlet C,Leibowitz SF

更新日期：1990-12-17 00:00:00

abstract：:Stroke is the major cause of acquired epilepsy in the adult population. The mechanisms of ischemia-induced epileptogenesis are not completely understood, but glutamate is associated with both ischemia-induced injury and epileptogenesis. The objective of this study was to develop an in vitro model of epileptogenesis in...

journal_title：Brain research

authors： Ziobro JM,Deshpande LS,Delorenzo RJ

更新日期：2011-01-31 00:00:00

abstract：:We have used the post-embedding immunogold labelling method using antibodies to gamma-aminobutyric acid (GABA) to obtain quantitative data on the distribution, frequency, postsynaptic targets and ultrastructural characteristics of GABA-immunoreactive (GABA-IR) boutons in the trigeminal motor nucleus of rats. We have a...

journal_title：Brain research

authors： Saha S,Appenteng K,Batten TF

更新日期：1991-10-04 00:00:00

abstract：:The bioelectric activity of the rat superior cervical ganglion (SCG) infected with pseudorabies virus (PRV) was examined in vitro 30-38 h after inoculation. Simultaneous intra- and extracellular recordings on the internal (ICN) and external carotid nerves (ECN) revealed a synchronized spontaneous activity. This synchr...

journal_title：Brain research

authors： Kiraly M,Dolivo M

更新日期：1982-05-20 00:00:00

abstract：:Using the histochemical Timm sulphide silver method, a strain-specific, increased stainability of the cell bodies of the dentate granule cells and the hippocampal pyramidal cells was observed in the inbred Kyoto rat. The resulting dense staining which also includes neurons in the neocortex and cerebellum can be used a...

journal_title：Brain research

authors： Finsen B,Zimmer J

更新日期：1986-09-01 00:00:00

abstract：:After the microinjection of morphine (5 micrograms/0.5 microliter) into the periaqueductal gray resulted in an increase in the hot-plate and tail-flick response latency of the unanesthetized rat, the alpha-adrenergic antagonists yohimbine, rauwolscine and corynanthine were given intrathecally. This treatment resulted ...

journal_title：Brain research

authors： Camarata PJ,Yaksh TL

更新日期：1985-06-10 00:00:00