Peripheral administration of a serine protease inhibitor blocks kindling.

abstract：:The developmental and age-related changes of the dopamine transporter (DAT), and the dopamine D1 and D2 receptor (D1R and D2R) subtypes were investigated in basal ganglia (BG) of human brain. DAT immunostaining was mainly observed in the neuropil, neurons, and glia of the striatum. The DAT-positive neuropil was detect...

journal_title：Brain research

authors： Meng SZ,Ozawa Y,Itoh M,Takashima S

更新日期：1999-10-02 00:00:00

abstract：:Nasal and temporal microexplants from the retina of the chicken embryo (E6; White Leghorn) were cultured on a collagen gel in the presence of extract from anterior or posterior E18 optic tectum. After 4 days of incubation maximum neurite lengths were measured as a function of protein concentration (1-500 micrograms/ml...

journal_title：Brain research

authors： Carri NG,Ebendal T

更新日期：1987-01-01 00:00:00

abstract：:It is well known that the nerve growth factor (NGF) may serve as a link between inflammation and hyperalgesia. Recent experiments showed that systemic injection of NGF dramatically stimulated the expression of brain-derived neurotrophic factor (BDNF) mRNA in the dorsal root ganglion (DRG). In the present study, we eva...

journal_title：Brain research

authors： Cho HJ,Kim SY,Park MJ,Kim DS,Kim JK,Chu MY

更新日期：1997-02-28 00:00:00

abstract：:Alpha-bungarotoxin binding sites in chick retina from 12 days in ovo to hatching, were visualized at the ultrastructural level by use of a 1:1 conjugate of horseradish peroxidase with alpha-bungarotoxin. At all stages binding sites in the inner plexiform layer were localized in synapses, predominantly on or near the p...

journal_title：Brain research

authors： Daniels MP,Vogel Z

更新日期：1980-11-10 00:00:00

abstract：:Glucocorticoid receptor (Gr) concentrations in the rat brain are low at the time of birth and increase towards adult levels during the first two weeks of life. Brief, daily handling of pups for the first 21 days postnatally has been found to permanently increase Gr concentrations within the hippocampus. Thus, the deve...

journal_title：Brain research

authors： Meaney MJ,Aitken DH

更新日期：1985-10-01 00:00:00

abstract：:Indirect immunofluorescence cytochemistry of ovine corticotropin releasing factor (oCRF) was performed by use of an antiserum raised against a conjugate of oCRF and bovine thyroglobulin. The staining intensity was quantitated by use of an automated microfluorimeter. In cryostat sections of formaldehyde fixed oCRF cont...

journal_title：Brain research

authors： Schipper J,Werkman TR,Tilders FJ

更新日期：1984-02-13 00:00:00

abstract：:The N-methyl-d-aspartate (NMDA) receptor, a glutamate receptor subtype, is a ligand-gated ion channel. Overstimulation of NMDA receptors may increase intracellular Ca2+ concentrations to lethal levels in neurodegenerative disorders affecting the basal ganglia. Such excitotoxicity may also contribute to the loss of med...

journal_title：Brain research

authors： Hopkins KJ,Oster-Granite ML

更新日期：1998-06-29 00:00:00

abstract：:The effects of amphetamine were examined in a brain stimulation reward paradigm in which response rate was measured across a range of stimulation frequencies. Both low (0.0625 and 0.125 mg/kg) and high (1.0, 2.0 and 4.0 mg/kg) doses of systemic amphetamine decreased the stimulation frequency needed to sustain low rate...

journal_title：Brain research

authors： Colle LM,Wise RA

更新日期：1988-09-06 00:00:00

abstract：:The purpose of this study was to determine the effects of aging and gender on the volumes of total brain, brainstem, cerebellum and lateral ventricle of healthy Koreans by magnetic resonance imaging (MRI). Using three-dimensional MRI volumetry, we compared the volumes of various brain regions according to age and gend...

journal_title：Brain research

authors： Lee NJ,Park IS,Koh I,Jung TW,Rhyu IJ

更新日期：2009-06-18 00:00:00

abstract：:The organization of the wing component of the dorsal column-medial lemniscal pathway, and somatosensory projections from the thalamus to the Wulst, are described for an oscine member of the major group of birds, the Passeriformes. Wing primary afferents terminate throughout the cervical spinal cord, but between the br...

journal_title：Brain research

authors： Wild JM

更新日期：1997-06-06 00:00:00

abstract：:Extracellular ATP can influence cells via activation of P2X purinoceptors, the distribution of which can be altered in the central and peripheral nervous systems following injury or tissue damage. Here we have investigated the effect of a unilateral section of the cervical vagus nerve on the distribution of P2X(1), P2...

journal_title：Brain research

authors： Atkinson L,Shigetomi E,Kato F,Deuchars J

更新日期：2003-07-04 00:00:00

abstract：:The luteinizing hormone-releasing hormone (LHRH) system of the platyfish Xiphophorus has been studied using immunohistochemistry and retrograde transport of horseradish peroxidase (HRP). Three different populations of LHRH-positive cell bodies are present in the brain, one in the ventral telencephalon at the border to...

journal_title：Brain research

authors： Münz H,Stumpf WE,Jennes L

更新日期：1981-09-21 00:00:00

abstract：:Previous electrophysiological as well as imaging research has contributed to the understanding of impairments in attention, executive functions, and memory in patients with attention-deficit/hyperactivity disorder (ADHD). However, there is a lack of studies investigating ADHD related differences in the gamma range of ...

journal_title：Brain research

authors： Lenz D,Krauel K,Schadow J,Baving L,Duzel E,Herrmann CS

更新日期：2008-10-15 00:00:00

abstract：:Commissural and ipsilateral intrinsic connections of the vestibular nuclear complex of cats were investigated using retrograde transport of horseradish peroxidase (HRP). HRP was microiontophoretically injected into limited areas (0.2-0.5 mm in diameter) of the respective vestibular nuclei. In the commissural connectio...

journal_title：Brain research

authors： Ito J,Matsuoka I,Sasa M,Takaori S

更新日期：1985-08-19 00:00:00

abstract：:Albino rats received 10 s of sub-seizure electrical stimulation applied to the dentate gyrus granule cells immediately after acquisition of information on trial 1 of a 2-trial radial maze spatial memory task. Granule cell stimulation selectively reduced the probability of accessing information held in declarative memo...

journal_title：Brain research

authors： Collier TJ,Routtenberg A

更新日期：1984-09-24 00:00:00

abstract：:Serotonin 1A receptor (5-HT(1A)R) agonists have emerged as valuable supplements to l-DOPA therapy, demonstrating that they can decrease side effects and enhance motor function in animal models of Parkinson's disease (PD) and human PD patients. The precise mechanism by which these receptors act remains unknown and ther...

journal_title：Brain research

authors： Dupre KB,Eskow KL,Negron G,Bishop C

更新日期：2007-07-16 00:00:00

abstract：:The postnatal development of acetylcholinesterase (AChE, EC 3.1.1.7) and NADH-diaphorase was examined in the caudate-putamen nucleus and substantia nigra of rats ranging from 3 to 90 days in age. From 3 to 15 days post partum islands of AChE and NADH-diaphorase activity were observed in the caudate-putamen nucleus. In...

journal_title：Brain research

authors： Butcher LL,Hodge GK

更新日期：1976-04-23 00:00:00

abstract：:Males show suppressed cell proliferation in the hippocampus in response to acute stress but no studies to date have examined cell proliferation in response to acute stress in females. In the current study, we examined the effects of acute exposure to a predator odor stressor [trimethyl thiazoline (TMT); the main compo...

journal_title：Brain research

authors： Falconer EM,Galea LA

更新日期：2003-06-13 00:00:00

abstract：:We used rabbit antisera against manganese (Mn)-superoxide dismutase for immunohistochemical studies of localization in the rat neostriatum. Immunostaining was intense in large-sized neurons and several medium-sized neurons, but it was moderate to weak in other cells. Double immunostaining with monoclonal antibody to c...

journal_title：Brain research

authors： Inagaki S,Suzuki K,Taniguchi N,Takagi H

更新日期：1991-05-17 00:00:00

abstract：:Several lines of evidence support a role for nerve growth factor (NGF) in the sympathetic sprouting response that occurs following septal cholinergic denervation of the rat hippocampal formation. The present study was undertaken to compare the distribution of NGF-like immunoreactivity and the topography of sympathetic...

journal_title：Brain research

authors： Yu C,Crutcher KA

更新日期：1995-02-20 00:00:00

abstract：:Porcine calcitonin (pCT) encapsulated in sulfatide-containing reverse-phase evaporation vesicles (REVs) was shown to induce long-lasting and dose-dependent antinociceptive effect by systemic injection in mice. Its antinociceptive activity is found to be dependent on the route of administration. In contrast, neither un...

journal_title：Brain research

authors： Chen D,Li QT,Lee KH

更新日期：1993-02-12 00:00:00

abstract：:(1) After inoculation of the pseudorabies virus in the anterior chamber of the eye of the rat, virions can be found only in the neurons of the superior cervical sympathetic ganglion and in the sensory ganglion of the fifth nerve on the inoculated side. Other nervous structures--central or peripheral--are not infected....

journal_title：Brain research

authors： Dolivo M,Beretta E,Bonifas V,Foroglou C

更新日期：1978-01-20 00:00:00

abstract：:A sample of 302 neurons in rat hindlimb granular cortex was studied between 2 and 3 weeks after transection and ligation of the sciatic nerve. These neurons were compared to a control sample obtained from normal rats under similar experimental conditions. After sciatic nerve transection the proportion of neurons drive...

journal_title：Brain research

authors： Dykes RW,Lamour Y

更新日期：1988-05-24 00:00:00

abstract：:Aging is accompanied by a general deterioration of fluid cognitive processes and a reduction in resting cerebral blood flow (CBF). While the two phenomena have been observed independently, it is uncertain whether individual differences in cerebral blood flow are reliably associated with cognitive functioning in older ...

journal_title：Brain research

authors： Heo S,Prakash RS,Voss MW,Erickson KI,Ouyang C,Sutton BP,Kramer AF

更新日期：2010-02-22 00:00:00

abstract：:A brief noxious heat stimulus applied to half of the receptive field of each cutaneous nociceptor resulted in most cases in the enhanced responsiveness of that half to subsequent heat stimuli (sensitization). No change in responsiveness to heat was observed in the other half of the receptive field, indicating that the...

journal_title：Brain research

authors： Thalhammer JG,LaMotte RH

更新日期：1982-01-14 00:00:00

abstract：:Molecular mechanism underlying ischemic stroke remains poorly understood. We previously reported glucose 6-phosphate dehydrogenase (G6PD) activity in pentose phosphate pathway (PPP) is activated via heat shock protein 27 (HSP27) phosphorylation at serine 85 (S85) by ataxia telangiectasia mutated (ATM) kinase during ce...

journal_title：Brain research

authors： Yamamoto Y,Hosoda K,Imahori T,Tanaka J,Matsuo K,Nakai T,Irino Y,Shinohara M,Sato N,Sasayama T,Tanaka K,Nagashima H,Kohta M,Kohmura E

更新日期：2018-05-15 00:00:00

abstract：:Somatostatin receptors have been identified in different brain areas but the characterization of their postreceptor effect is still lacking. In this study we analyze the somatostatin effect on adenylate cyclase activity in different brain regions, namely frontal cortex, striatum, hypothalamus and hippocampus. Somatost...

journal_title：Brain research

authors： Schettini G,Florio T,Meucci O,Landolfi E,Grimaldi M,Ventra C,Marino A

更新日期：1989-07-17 00:00:00

abstract：:The autoradiographic [14C]2-deoxyglucose (2-DG) method was used to map ascending pathways which are influenced by arousing electrical stimulation of the midbrain reticular formation (RET) in alert rats. The major finding was that RET stimulation produces selective patterns of metabolic activation and suppression in di...

journal_title：Brain research

authors： Gonzalez-Lima F,Scheich H

更新日期：1985-09-30 00:00:00

abstract：:The effects of cocaine administration and withdrawal on D1 and D2 dopamine receptor number, affinity, and mRNA levels were examined in rats trained to self-administer cocaine for four weeks on a continuous reinforcement schedule. Two hours after the last infusion of cocaine there was a decrease in the number and agoni...

journal_title：Brain research

authors： Laurier LG,Corrigall WA,George SR

更新日期：1994-01-14 00:00:00

abstract：:Excitatory amino acid neurotoxicity and the inflammatory response are suspected as mediators of some of the pathological sequelae occurring as a result of spinal cord injury. Here we report temporal and regional increases of the NMDA receptor agonist, quinolinic acid (QUIN), in an experimental model of spinal contusio...

journal_title：Brain research

authors： Popovich PG,Reinhard JF Jr,Flanagan EM,Stokes BT

更新日期：1994-01-07 00:00:00