Vagus nerve stimulation produces a hippocampal formation theta rhythm in anesthetized rats.

abstract：:We investigated the effect of beta-estradiol (E2) on synaptogenesis in the hippocampus using organotypic hippocampal slice cultures and subregional hippocampal neuron cultures. E2 increased the expression of PSD95, a postsynaptic marker, specifically in stratum lucidum of Cornu Ammonis 3 (CA3SL) in cultured hippocampa...

journal_title：Brain research

authors： Sato K,Akaishi T,Matsuki N,Ohno Y,Nakazawa K

更新日期：2007-05-30 00:00:00

abstract：:As in many humans suffering from lupus erythematosus, the development of systemic autoimmunity and inflammation in Fas-deficient MRL-lpr mice is accompanied by CNS dysfunction of unknown etiology. Experimental studies revealed infiltration of lymphoid cells into the choroid plexus, reduced neuronal complexity, retarde...

journal_title：Brain research

authors： Ballok DA,Millward JM,Sakic B

更新日期：2003-02-28 00:00:00

abstract：:Retinotectal projections were studied in 33 different species of Actinopterygii, the ray-finned fishes, with horseradish peroxidase and cobalt tracing techniques. The distribution of retinorecipient layers in the contralateral optic tectum was analyzed. In addition, the degree of differentiation of the stratum periven...

journal_title：Brain research

authors： von Bartheld CS,Meyer DL

更新日期：1987-09-15 00:00:00

abstract：:This report examines the effect of decreasing serum osmolality on movement into the ventricular system of fluid and of test material injected into the brain. Trace quantities of 22NaCl and 125I-labeled cat serum albumin (CSA) were injected into cerebral white matter of cats. The rates of cerebrospinal fluid volume flo...

journal_title：Brain research

authors： Wald A,Hochwald GM,Gandhi M

更新日期：1978-08-04 00:00:00

abstract：:We investigated the effect of focal cerebral ischaemia on the activity and the affinity of the ouabain sites of Na+,K+-ATPase in the mouse. The Na+,K+-ATPase activity was decreased by 38% as early as 30 min following ischaemia. In the sham group, the dose-response curves for ouabain disclosed three inhibitory states w...

journal_title：Brain research

authors： Jamme I,Petit E,Gerbi A,Maixent JM,MacKenzie ET,Nouvelot A

更新日期：1997-11-07 00:00:00

abstract：:Growth of cultured N1E-115 neuroblastoma cells in 1 microM A23187 for 2 days to elevate internal Ca reduced both membrane Na current and the transient, but not steady state, component of outward K current. Na channel mRNA abundance was reduced by an average value of 45% without effect on Kv3.1. Increases in internal C...

journal_title：Brain research

authors： Hirsh JK,Quandt FN

更新日期：1996-01-15 00:00:00

abstract：:Previously, we have shown that intracisternal (i.c.) administration of beta-endorphin suppresses brain and liver DNA synthesis in rat pups. This finding is consistent with the view that endogenous CNS beta-endorphin plays an important role in controlling postnatal growth. Recent evidence suggests that brain CCK8, the ...

journal_title：Brain research

authors： Bartolome JV,Lorber BA,Bartolome MB

更新日期：1994-10-24 00:00:00

abstract：:Chick pineal cells contain a circadian oscillator that derives rhythmic synthesis and secretion of melatonin even in dispersed cell culture. Here, we demonstrate that the mRNA encoding tryptophan hydroxylase (TPH), the first enzyme in the melatonin synthetic pathway, is expressed rhythmically under the control of the ...

journal_title：Brain research

authors： Green CB,Besharse JC,Zatz M

更新日期：1996-10-28 00:00:00

abstract：:The aim of this study was to determine if a prolonged period (7 or 14 days) of hypodynamia-hypokinesia (HH) affects the conduction of afferent input and the cortical and spinal responsiveness. Acute recordings of cortical and spinal somatosensory evoked potentials (SEPs) were performed after stimulation of the sciatic...

journal_title：Brain research

authors： Canu MH,Langlet C,Dupont E,Falempin M

更新日期：2003-07-18 00:00:00

abstract：:Glycoprotein M6a is a neuronally expressed member of the proteolipid protein (PLP) family of tetraspans. In vitro studies suggested a potential role in neurite outgrowth and spine formation and previous investigations have identified M6a as a stress-regulated gene. To investigate whether the distribution of M6a correl...

journal_title：Brain research

authors： Cooper B,Werner HB,Flügge G

更新日期：2008-03-04 00:00:00

abstract：:The ionic mechanism of the membrane permeability changes caused by L-glutamate in hippocampal neurons prepared from 17- to 19-day-old fetal rat in dispersed cell cultures was studied with the whole-cell variation of the patch electrode voltage-clamp technique. The cultured hippocampal neurons became sensitive to gluta...

journal_title：Brain research

authors： Ozawa S,Nakamura T,Yuzaki M

更新日期：1988-03-08 00:00:00

abstract：:Tumor suppressor p53 has recently been reported to have numerous functions independent of tumorigenesis, including neuronal survival during ischemia. The mammalian target of rapamycin (mTOR) signaling pathway plays a central role in the regulation of metabolism, cell growth, development, and cell survival. Our recent ...

journal_title：Brain research

authors： Li X,Gu S,Ling Y,Shen C,Cao X,Xie R

更新日期：2015-04-24 00:00:00

abstract：:Superfusion of slices of the dorsal zone of the lumbar enlargement with an artificial cerebrospinal fluid was used to investigate the possible modulation by GABA receptor ligands of the in vitro release of calcitonin gene-related peptide- and substance P-like materials (CGRPLM and SPLM) from the rat spinal cord. Where...

journal_title：Brain research

authors： Bourgoin S,Pohl M,Benoliel JJ,Mauborgne A,Collin E,Hamon M,Cesselin F

更新日期：1992-06-26 00:00:00

abstract：:Chick neural cultures were used to study effects of insulin, thyrotropin releasing hormone, growth hormone and glucagon on myelin lipid synthesis in vitro. The incorporation of [3H]galactose into myelin associated lipids such as cerebroside and sulfatide was used as an index for various hormonal effects on myelination...

journal_title：Brain research

authors： Kanamoto Y,Karashima H,Kim SU,Eto Y

更新日期：1986-04-16 00:00:00

abstract：:We studied the effects of axotomy or neurotoxin on the survival of substantia nigra pars compacta (SNpc) neurons in two strains of mice, FVB/N or C57BL/6. Fluoro gold (FG) was injected into both striata of the mice to retrogradely label the nigrostriatal neuronal population. Ten days later, these neurons were axotomiz...

journal_title：Brain research

authors： Liu L,Hsu SS,Kalia SK,Lozano AM

更新日期：2003-12-24 00:00:00

abstract：:The hypothalamic angiotensin II (Ang II) system plays an important role in pituitary hormone release. Little is known about this system in the mouse brain. We studied the distribution of angiotensin-converting-enzyme (ACE), Ang II, Ang II receptor subtypes, and vasopressin in the hypothalamus of adult male mice. Autor...

journal_title：Brain research

authors： Jöhren O,Imboden H,Häuser W,Maye I,Sanvitto GL,Saavedra JM

更新日期：1997-05-23 00:00:00

abstract：:Transient ischemic attack (TIA) has received only little attention in the experimental research field. Recently, we introduced a TIA model for mice, and here we set similar principles for simulating this human condition in Wistar rats. In the model: 1) transient nature of the event is ensured, and 2) 24h after the eve...

journal_title：Brain research

authors： Durukan Tolvanen A,Tatlisumak E,Pedrono E,Abo-Ramadan U,Tatlisumak T

更新日期：2017-05-15 00:00:00

abstract：:The specific binding of [3H]kainic acid to hippocampal membranes was examined autoradiographically in rats kindled by tetanic stimulation of the amygdala or angular bundle. One day after the last of 3 class 4-5 kindled seizures, the specific binding of [3H]kainic acid in stratum lucidum of area CA3 was 47-61% less tha...

journal_title：Brain research

authors： Savage DD,Nadler JV,McNamara JO

更新日期：1984-12-03 00:00:00

abstract：:Fasting induced a reduction in neuronal nitric oxide synthase (nNOS) mRNA in the paraventricular nucleus (PVN) and supraoptic nucleus (SON) of rats. The effect of intracerebroventricular (i.c.v.) administration of leptin on the nNOS mRNA level in the PVN and SON of fasting rats was studied by in situ hybridization his...

journal_title：Brain research

authors： Isse T,Ueta Y,Serino R,Noguchi J,Yamamoto Y,Nomura M,Shibuya I,Lightman SL,Yamashita H

更新日期：1999-11-06 00:00:00

abstract：:Female golden-mantled ground squirrels that sustained complete ablation of the suprachiasmatic nucleus (SCNx) were housed pre- and post-operatively at 23 degrees C and then at 6.5 degrees C for 5-7 yr. SCNx and control animals held at the higher temperature manifested circannual rhythms (CARs) in body mass. In contras...

journal_title：Brain research

authors： Ruby NF,Dark J,Heller HC,Zucker I

更新日期：1998-01-26 00:00:00

abstract：:Plasma concentrations of beta-endorphin were measured by radioimmunoassay in cats prepared chronically for sleep-waking polygraphic recordings and blood collection. beta-Endorphin (beta-END) levels were found to be stable in baseline conditions and were used as an index of stress. After habituation of each cat to expe...

journal_title：Brain research

authors： Foutz AS,Dauthier C,Kerdelhué B

更新日期：1983-03-14 00:00:00

abstract：:We have examined the effects of isotonic hypovolemia on the expression of the neuronal nitric oxide synthase (nNOS) gene in the paraventricular (PVN) and supraoptic nuclei (SON) of the rat, using in situ hybridization histochemistry with a 35S-labelled oligodeoxynucleotide probe complementary to nNOS mRNA. Intraperito...

journal_title：Brain research

authors： Ueta Y,Levy A,Lightman SL,Hara Y,Serino R,Nomura M,Shibuya I,Hattori Y,Yamashita H

更新日期：1998-04-20 00:00:00

abstract：:We employed a highly sensitive combination method of retrograde tracing and immunohistochemistry to identify calcitonin gene-related peptide (CGRP)-containing fiber pathways in the rat from the ventrolateral part of the ventrolateral thalamic nucleus (vl-vl) and the caudal continuation to the insular cortex. Biotin-wh...

journal_title：Brain research

authors： Shimada S,Shiosaka S,Hillyard CJ,Girgis SI,MacIntyre I,Emson PC,Tohyama M

更新日期：1985-09-30 00:00:00

abstract：:Saccadic adaptation maintains saccade accuracy and has been studied with targeting saccades, i.e. saccades that bring the gaze to a target, with the classical intra-saccadic step procedure in which the target systematically jumps to a new position during saccade execution. Post-saccadic visual feedback about the error...

journal_title：Brain research

authors： Lavergne L,Vergilino-Perez D,Lemoine C,Collins T,Doré-Mazars K

更新日期：2011-09-30 00:00:00

abstract：:PGP 9.5 is a new cytoplasmic neuron-specific protein structurally and immunologically distinct from neuron-specific enolase. A specific antiserum has now shown that this protein is widely distributed in vertebrate brains and is also present in cells of the human diffuse neuroendocrine system. PGP 9.5 appears to be old...

journal_title：Brain research

authors： Thompson RJ,Doran JF,Jackson P,Dhillon AP,Rode J

更新日期：1983-11-14 00:00:00

abstract：:The newly identified neuropeptide nociceptin/orphanin FQ (NOC) was measured in different rat brain areas related to the descending anti-nociceptive pathways and compared to two opioid peptides, dynorphin B (DYN B) and Met-enkephalinArgPhe (MEAP). Two experimental models of chronic nociception, one neurogenic and one i...

journal_title：Brain research

authors： Rosén A,Lundeberg T,Bytner B,Nylander I

更新日期：2000-02-28 00:00:00

abstract：:In many persons with temporal lobe epilepsy, dentate granule cells form an interconnected synaptic network. This recurrent mossy fiber circuit mediates reverberating excitation that may facilitate seizure propagation by synchronizing granule cell discharge. The involvement of specific glutamate receptors in granule ce...

journal_title：Brain research

authors： Okazaki MM,Nadler JV

更新日期：2001-10-05 00:00:00

abstract：:Concentrations of the neurotransmitters, serotonin (5-HT), dopamine (DA), and norepinephrine (NE) were measured in the developing rat brain at 12, 19, 26 and 42 days of age. The amino acid precursors, tryptophan (TRP) and tyrosine (TYR) were measured along with the 5-HT and DA metabolites, 5-hydroxyindoleacetic acid (...

journal_title：Brain research

authors： Shaywitz BA,Anderson GM,Cohen DJ

更新日期：1985-01-01 00:00:00

abstract：:Corticotropin releasing hormone (CRH) plays a major role in central nervous system responses to stressors and has been implicated in stress-induced alterations in sleep. In the absence of stressors, CRH contributes to the regulation of spontaneous waking. We examined the effects of CRH and astressin (AST), a non-speci...

journal_title：Brain research

authors： Sanford LD,Yang L,Wellman LL,Dong E,Tang X

更新日期：2008-01-23 00:00:00

abstract：:Regulation of the intracellular calcium concentration ([Ca(2+)](i)) is of critical importance for synaptic function. Therefore, neurons buffer [Ca(2+)](i) using intracellular Ca(2+)-binding proteins (CaBPs). Previous evidence suggests that Calbindin-D(28K) (CB), an abundantly expressed endogenous fast CaBP, plays an i...

journal_title：Brain research

authors： Westerink RH,Beekwilder JP,Wadman WJ

更新日期：2012-04-23 00:00:00