Morphology of sweat glands in determining time of death.


:This study demonstrates post-mortem autolytic alterations in the skin at cellular and subcellular levels and identifies parameters which may assist in determining the time of death in the first few hours post-mortem. Serial skin samples from the ventral surface of the arm were taken at intervals of 3, 6, 9 and 12 h after death in 29 subjects of various ages, with no signs of skin disease; causes of death were various. Three types of tests were performed: cytochemical (hematoxylin-eosin and alcian-PAS), immunohistochemical (S-100, CEA, Cytokeratin, ASM) and ultrastructural (electron microscopy). Electron microscopy proved useful for identifying transformations which were found to be specific for each chronological step considered: reduction of intracellular glycogen in clear cells and reduction of secretory granules in dark cells are typical signs of the first stage (3 h) after death; mitochondrial dilatation and rarefaction of cristae in clear and dark cells are typical of the second stage (6 h); rarefaction of microvilli in dark and clear cells is a sign of the last stage (12 h). Cytochemistry and immunohistochemistry supply useful information--not for all the chronological stage considered here, but for individual phases (3 h for hematoxylin-eosin and 6 h for alcian-PAS). However, it is particularly important to use the results from all such techniques simultaneously, so that the question of the exact time of death within the first 12 h post-mortem may be more accurately answered.


Int J Legal Med


Cingolani M,Osculati A,Tombolini A,Tagliabracci A,Ghimenton C,Ferrara SD




Has Abstract


1994-01-01 00:00:00












  • Analysis of Y chromosome STR haplotypes in the European part of Russia reveals high diversities but non-significant genetic distances between populations.

    abstract::A total of 17 Y-specific STR loci were studied in 12 districts of the European part of Russia aiming to ascertain the amount of substructure required for the construction of a representative regional database. All groups exhibited high haplotype diversities but low inter-population variance as measured by an analysis ...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章


    authors: Roewer L,Willuweit S,Krüger C,Nagy M,Rychkov S,Morozowa I,Naumova O,Schneider Y,Zhukova O,Stoneking M,Nasidze I

    更新日期:2008-05-01 00:00:00

  • Dental age estimation in living individuals using 3.0 T MRI of lower third molars.

    abstract::In order to increase the validity of age estimation in adolescents and young adults when there is no legitimation for X-ray examinations, it seems desirable to be able to assess the mineralization of third molars using X-ray-free imaging procedures. In the present study, the mineralization stages of lower third molars...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章


    authors: Guo Y,Olze A,Ottow C,Schmidt S,Schulz R,Heindel W,Pfeiffer H,Vieth V,Schmeling A

    更新日期:2015-11-01 00:00:00

  • STR analysis on perforating FMJ bullets and a new VWA variant allele.

    abstract::In three separate shooting incidents involving multiple gunshots, two FMJ bullets and one bullet fragment found at the scene (one from each case) were investigated for the presence of biological material from the victim after perforation. The surface of the missiles, which did not show obvious tissue traces when exami...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章


    authors: Karger B,Meyer E,DuChesne A

    更新日期:1997-01-01 00:00:00

  • Population genetics of 26 Y-STR loci for the Han ethnic in Hunan province, China.

    abstract::To study the population data of Y-chromosome STRs (Y-STRs) of Han population resided in Hunan province, we analyzed haplotypes of 26 Y-STRs (DYS19, DYS385a/b, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS481, DYS533, DYS549, DYS570, DYS576, DYS635, DYS643, DYS38...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章,评审


    authors: Jiang W,Gong Z,Rong H,Guan H,Zhang T,Zhao Y,Fu X,Zha L,Jin C,Ding Y

    更新日期:2017-01-01 00:00:00

  • Forensic 3D documentation of skin injuries.

    abstract::An accurate and precise documentation of injuries is fundamental in a forensic pathological context. Photographs and manual measurements are taken of all injuries during autopsies, but ordinary photography projects a 3D wound on a 2D space. Using technologies such as photogrammetry, it is possible to create 3D detaile...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章


    authors: Villa C

    更新日期:2017-05-01 00:00:00

  • Application of the method of Kvaal et al. to digital orthopantomograms.

    abstract::Estimation of age in individuals has received considerable attention in the forensic literature. The reduction of size of dental pulp cavity as a result of secondary dentin deposit with increasing age could be used as an indicator of age. This regression change, apart from morphological techniques, can also be analyse...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章


    authors: Landa MI,Garamendi PM,Botella MC,Alemán I

    更新日期:2009-03-01 00:00:00

  • Fatality following a suicidal overdose with varenicline.

    abstract::The smoking cessation agent varenicline acts as a partial agonist on α(4)β(2) nicotinic acetylcholine receptors. Although debated, several reports have linked varenicline therapy to an increased risk of suicidal thoughts and/or suicide. In addition, several non-fatal overdose cases have been reported. In this report, ...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章


    authors: Stove CP,De Letter EA,Piette MH,Lambert WE

    更新日期:2013-01-01 00:00:00

  • A new "miniSTR-multiplex" displaying reduced amplicon lengths for the analysis of degraded DNA.

    abstract::A multiplex PCR was designed for the loci D2S1338, D16S539, D18S51, TH01 and FGA using redesigned primers in order to reduce the lengths of the amplification products compared to the designs used in commercially available multiplex PCR kits, also including amelogenin. The new PCR primers were used to amplify highly de...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章


    authors: Grubwieser P,Mühlmann R,Berger B,Niederstätter H,Pavlic M,Parson W

    更新日期:2006-03-01 00:00:00

  • The analysis of temporal gene expression to estimate the age of forensically important blow fly pupae: results from three blind studies.

    abstract::The estimation of the minimum postmortem interval can be implemented by age estimation of corpse-associated primary colonizers such as the blow flies (Diptera: Calliphoridae). In cases where pupae represent the oldest stages found on a body, their age must be added to the duration of prepupal development to estimate t...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章


    authors: Boehme P,Spahn P,Amendt J,Zehner R

    更新日期:2014-05-01 00:00:00

  • Genetic analysis of 29 Y-STR loci in Han population from Dongfang, Southern China.

    abstract::In the present study, blood samples of 984 unrelated Han individuals were collected from Dongfang, Southern China, after informed consent. A total of 29 Y-chromosomal short tandem repeat (Y-STR) were analyzed, including DYF387S1, DYS19, DYS385ab, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438, DYS43...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章


    authors: Zhang J,Mo X,Shang L,Jin X,Chen D,Zhu H,Zhang Y,Kang B,Li W,Ye J

    更新日期:2019-07-01 00:00:00

  • Expression of heat-shock protein 70 (Hsp70) in the respiratory tract and lungs of fire victims.

    abstract::Immunohistochemical investigation of the respiratory tract and lungs of 63 fire victims revealed a statistically significant enhanced expression of heat-shock protein 70 (Hsp70) in the epiglottis, the trachea, and the main and the peripheral bronchi compared with a control group. In the fire victims, a strong expressi...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章


    authors: Marschall S,Rothschild MA,Bohnert M

    更新日期:2006-11-01 00:00:00

  • Distribution of kerosene components in rats following dermal exposure.

    abstract::The systemic distribution of kerosene components in blood and tissues was analysed in rats following dermal exposure. Four types of trimethylbenzenes (TMBs) and aliphatic hydrocarbons (AHCs) with carbon numbers 9-16 (C(9)-C(16)) were analysed as major kerosene components by capillary gas chromatography/mass spectromet...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章


    authors: Tsujino Y,Hieda Y,Kimura K,Eto H,Yakabe T,Takayama K,Dekio S

    更新日期:2002-08-01 00:00:00

  • Characterization of haemorrhages at the origin of the sternocleidomastoid muscles in hanging.

    abstract::Haemorrhages at the periostal-clavicular origin of the sternocleidomastoid muscles were found in 52 out of 54 cases of death by hanging. This cervical haemorrhage is most frequently found in death by hanging, but only seldomly seen in other causes of death and can therefore be regarded as being typical for death by ha...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章


    authors: Keil W,Forster A,Meyer HJ,Peschel O

    更新日期:1995-01-01 00:00:00

  • Development of two multiplex PCR systems for the analysis of 14 X-chromosomal STR loci in a southern Brazilian population sample.

    abstract::We developed two multiplex systems for the coamplification of X-chromosomal short tandem repeats (STRs). X-Multiplex 1 consisted of DXS6807, DXS6800, DXS7424, DXS101, GATA172D05 and HPRTB and X-Multiplex 2 consisted of DXS8378, DXS9898, DXS6801, DXS6809, DXS6789, DXS7133, DXS8377 and DXS7423. In addition, we present a...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章


    authors: Penna LS,Silva FG,Salim PH,Ewald G,Jobim M,Magalhães JA,Jobim LF

    更新日期:2012-03-01 00:00:00

  • Hand skin reconstruction from skeletal landmarks.

    abstract::Many studies related to three-dimensional facial reconstruction have been previously reported. On the other hand, no extensive work has been found in the literature about hand reconstruction as an identification method. In this paper, the feasibility of virtual reconstruction of hand skin based on (1) its skeleton and...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章


    authors: Lefèvre P,Van Sint Jan S,Beauthier JP,Rooze M

    更新日期:2007-11-01 00:00:00

  • Using bone marrow matrix to analyze meprobamate for forensic toxicological purposes.

    abstract::Bone marrow (BM) analysis is of forensic interest for postmortem toxicological investigations where blood samples are unavailable or unusable. Due to the lack of studies, it remains difficult to interpret concentrations of xenobiotics measured in this matrix. Based on a statistical approach published previously to int...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章


    authors: Bévalot F,Gustin MP,Cartiser N,Gaillard Y,Le Meur C,Fanton L,Guitton J,Malicier D

    更新日期:2013-09-01 00:00:00

  • Metal pins fired from unmodified blank cartridge guns and very small calibre weapons--technical and wound ballistic aspects.

    abstract::Blank cartridge guns are generally regarded as being harmless and are not considered to be firearms in most countries. A comparison of the legal situations in Germany and Austria concerning weapons is given. There have been several reports of serious injuries and even fatalities due to these weapons. Ballistic experim...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章


    authors: Rabl W,Riepert T,Steinlechner M

    更新日期:1998-01-01 00:00:00

  • Analysis of linkage and linkage disequilibrium for syntenic STRs on 12 chromosomes.

    abstract::The purpose of this study is to evaluate allelic association and linkage of 18 adjacent syntenic short tandem repeat (STR) pairs form out of 30 markers located on 12 different autosomes. Linkage disequilibrium was tested by using the unknown gametic phase genotypes and phased haplotypes from 290 unrelated individuals ...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章


    authors: Wu W,Hao H,Liu Q,Han X,Wu Y,Cheng J,Lu D

    更新日期:2014-09-01 00:00:00

  • The combined evidential value of autosomal and Y-chromosomal DNA profiles obtained from the same sample.

    abstract::When a Y-chromosomal and a (partial) autosomal DNA profile are obtained from one crime sample, and both profiles match the suspect's profiles, we would like to know the combined evidential value. To calculate the likelihood ratio of observing the autosomal and Y-chromosomal DNA profiles combined, we need to know the c...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章


    authors: de Zoete J,Sjerps M,Meester R,Cator E

    更新日期:2014-11-01 00:00:00

  • DNA typing of epithelial cells after strangulation.

    abstract::DNA typing was carried out on epithelial cells which were transferred from the hands of the suspect onto the neck of the victim. In an experimental study 16 suspect-victim combinations were investigated for estimating the typing success. Alternatively to an attack against the neck, the upper arm was used for "strangul...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章


    authors: Wiegand P,Kleiber M

    更新日期:1997-01-01 00:00:00

  • New bone post-processing tools in forensic imaging: a multi-reader feasibility study to evaluate detection time and diagnostic accuracy in rib fracture assessment.

    abstract:PURPOSE:The aim of this multi-reader feasibility study was to evaluate new post-processing CT imaging tools in rib fracture assessment of forensic cases by analyzing detection time and diagnostic accuracy. MATERIALS AND METHODS:Thirty autopsy cases (20 with and 10 without rib fractures in autopsy) were randomly select...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章


    authors: Glemser PA,Pfleiderer M,Heger A,Tremper J,Krauskopf A,Schlemmer HP,Yen K,Simons D

    更新日期:2017-03-01 00:00:00

  • Superimposition technique for skull identification with Afloat® software.

    abstract::The craniofacial superimposition technique is still an important way of identifying skulls when there is no reference sample for a forensic DNA analysis, when DNA typing from remaining tissue samples has failed, or when antemortem dental records are not available. Through the widespread use of digital photography, the...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章


    authors: Birngruber CG,Kreutz K,Ramsthaler F,Krähahn J,Verhoff MA

    更新日期:2010-09-01 00:00:00

  • Genomic portrait of population of Jharkhand, India, drawn with 15 autosomal STRs and 17 Y-STRs.

    abstract::We analysed 15 autosomal STRs in 200 unrelated individuals (102 males and 98 females) and 17 Y-STRs in 102 unrelated males living in Jharkhand, India, to establish parameters of forensic interest. The examined autosomal STRs revealed high combined power of exclusion (CPE) and combined power of discrimination (CPD) as ...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章


    authors: Imam J,Reyaz R,Singh RS,Bapuly AK,Shrivastava P

    更新日期:2018-01-01 00:00:00

  • The use of post-mortem computed tomography in the investigation of intentional neonatal upper airway obstruction: an illustrated case.

    abstract::We present a single case report illustrating the diagnostic role of multi-slice computed tomography (MSCT) in the investigation of suspicious child death where mechanical asphyxia is suspected. The case illustrates how radiological findings that may not be observable on conventional plain X-ray were identified by post...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章


    authors: Rutty GN,Jeffery AJ,Raj V,Morgan B

    更新日期:2010-11-01 00:00:00

  • Are coding systems of frontal sinuses anatomically reliable? A study of correlation among morphological and metrical features.

    abstract::Frontal sinuses are of special interest for personal identification thanks to their high variability. A common procedure for comparing ante-mortem and post-mortem material is based on coding systems classifying frontal sinuses according to their morphological and metrical characteristics. However, the calculation of p...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章


    authors: Gibelli D,Cellina M,Gibelli S,Oliva AG,Termine G,Sforza C

    更新日期:2020-09-01 00:00:00

  • Correction to: Mixture deconvolution by massively parallel sequencing of microhaplotypes.

    abstract::The original version of this article contained an author name error. In this article, Katrina Madella has been corrected to Katrina Maddela. ...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章,已发布勘误


    authors: Bennett L,Oldoni F,Long K,Cisana S,Maddela K,Wootton S,Chang J,Hasegawa R,Lagacé R,Kidd KK,Podini D

    更新日期:2019-05-01 00:00:00

  • Comparison of HPLC and CE for the analysis of dichlorprop in a case of intoxication.

    abstract::A 49-year-old white male was found lying unconscious at home. He had vomited, his mouth was filled with a white foam and a pungent odour filled the room. After emergency treatment blood, urine and stomach contents were screened for drugs after acid and alkaline extraction with subsequent derivatisation and GC-MS analy...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章


    authors: West A,Frost M,Köhler H

    更新日期:1997-01-01 00:00:00

  • Intraindividual incongruences of medially ossifying clavicles in borderline adults as seen from thin-slice CT studies of 2595 male persons.

    abstract::In the past, numerous studies have documented the possibility of intraindividual differing appearances of the paired age-marker "medial clavicular ossification" in borderline adults. However, the extent of the divergences is rarely mentioned. Against that the article describes this phenomenon from a large sample of 25...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章


    authors: Rudolf E,Kramer J,Schmidt S,Vieth V,Winkler I,Schmeling A

    更新日期:2018-03-01 00:00:00

  • Frequency and influencing factors of cardiopulmonary resuscitation-related injuries during implementation of the American Heart Association 2010 Guidelines: a retrospective study based on autopsy and postmortem computed tomography.

    abstract:AIM:To determine the frequency of cardiopulmonary resuscitation (CPR)-related injuries and factors involved in their occurrence, data based on forensic autopsy and postmortem computed tomography (PMCT) during implementation of the 2010 American Heart Association Guidelines for CPR were studied. METHODS:We retrospectiv...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章


    authors: Yamaguchi R,Makino Y,Chiba F,Torimitsu S,Yajima D,Inokuchi G,Motomura A,Hashimoto M,Hoshioka Y,Shinozaki T,Iwase H

    更新日期:2017-11-01 00:00:00

  • Rather yield than break: assessing the influence of human bone collagen content on heat-induced warping through vibrational spectroscopy.

    abstract::Warping has been used to determine the pre-burning condition of human skeletal remains. In the literature, this modification has been associated more often with the burning of fleshed and green bones, but it also arises during the burning of dry bones. The objective of this paper was to assess if bone collagen content...

    journal_title:International journal of legal medicine

    pub_type: 杂志文章


    authors: Vassalo AR,Cunha E,de Carvalho LA,Gonçalves D

    更新日期:2016-11-01 00:00:00