Abstract:
:A 32-year-old patient died of a cerebellar haemorrhage and the blood coagulation analysis before death suggested defective synthesis of vitamin K-dependent clotting factors due to vitamin K deficiency. The post-mortem toxicological examination of different tissues revealed phenprocoumon poisoning as the cause of death. The differential diagnosis of vitamin K deficiency and the toxicology of hydroxycoumarins are discussed.
journal_name
Int J Legal Medjournal_title
International journal of legal medicineauthors
Höhler T,Becker J,Meyer zum Büschenfelde KH,Rittner Cdoi
10.1007/BF01369825subject
Has Abstractpub_date
1996-01-01 00:00:00pages
268-71issue
5eissn
0937-9827issn
1437-1596journal_volume
108pub_type
杂志文章abstract::During forensic investigations, it is often important to be able to distinguish between impact spatter patterns (blood from gunshots, explosives, blunt force trauma and/or machinery accidents) and bloodstain patterns generated by expiration (blood from the mouth, nose or lungs). These patterns can be difficult to dist...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-010-0498-5
更新日期:2011-11-01 00:00:00
abstract::ABO blood grouping of human bloodstains was performed by a sandwich ELISA using a species-specific monoclonal antibody to the amino-terminal cytoplasmic domain of human red cell membrane band 3. In a blind trial, all A, B and O bloodstains (a 1 cm long thread) and AB bloodstains (a 1.5 cm long thread) were accurately ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01642795
更新日期:1993-01-01 00:00:00
abstract::The purpose of this study was to explore the applicability of periodontal ligament visibility (PLV) at the 18-year threshold. This mandibular maturity marker is graded into four separate age related stages, PLV-A, PLV-B, PLV-C, and PLV-D. These are discernible on a dental panoramic tomograph (DPT). The sample comprise...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-016-1468-3
更新日期:2017-05-01 00:00:00
abstract::In this study the development of a 13-locus multiplex-PCR system fitting the updated demands for paternity testing in Germany is described. For this purpose an existing multiplex PCR system that allows the simultaneous amplification of eight different STR loci together with the sex-specific locus amelogenin ( genRESMP...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-003-0420-5
更新日期:2004-02-01 00:00:00
abstract::The sequences of the hypervariable region 1 (HV1) of the mitochondrial DNA control region from multiple hair shafts from 10 unrelated individuals were compared to determine the frequency of differences in hairs from one individual. The extraction method described herein showed an average success rate of 67% for all 15...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050226
更新日期:1999-01-01 00:00:00
abstract::Bee and wasp stings represent an uncommon cause of death. In a retrospective study of all fatalities due to venomous animals in Sweden during a 10-year-period, we found 19 fatalities due to wasps, 1 due to bees but none due to snake bite. This gives an annual incidence of 0.2 per million inhabitants. Most of the decea...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01626039
更新日期:1991-03-01 00:00:00
abstract::Population genetic studies were carried out on randomly selected and unrelated healthy individuals from Sicily (n = 140-150 individuals) using the short tandem repeat (STR) systems HumTH01, HumvWA31, HumFESFPS and HumF13A01. After vertical electrophoresis on polyacrylamide denaturing gels 6 alleles could be identified...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050171
更新日期:1998-01-01 00:00:00
abstract::An 89-year-old woman was found dead lying in her bed. Autopsy demonstrated a pronounced thickening of all coronary arteries except for the first 2-4 cm. Death was due to a recent myocardial infarction. Microscopically, the coronary arteries showed a substantial concentric thickening of all three layers with 90% narrow...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-006-0090-1
更新日期:2006-11-01 00:00:00
abstract:AIM:To determine the frequency of cardiopulmonary resuscitation (CPR)-related injuries and factors involved in their occurrence, data based on forensic autopsy and postmortem computed tomography (PMCT) during implementation of the 2010 American Heart Association Guidelines for CPR were studied. METHODS:We retrospectiv...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-017-1673-8
更新日期:2017-11-01 00:00:00
abstract::The morphological structure and immunohistochemical reactions of 100 pituitaries from cases of SIDS children (58 males and 42 females, average age 5.34 +/- 3.12 months) were studied. Controls consisted of 19 pituitaries from children (14 males and 5 females, average age 5.63 +/- 2.52 months) with a clearly identifiabl...
journal_title:International journal of legal medicine
pub_type: 杂志文章,多中心研究
doi:10.1007/BF01225414
更新日期:1994-01-01 00:00:00
abstract::The main criteria used in dental age estimation in living young individuals are mineralisation and eruption of the third molars. In order to further diversify the spectrum of characteristics after completion of third molar development, tests were undertaken to determine whether the characteristics studied by Gustafson...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-012-0701-y
更新日期:2012-07-01 00:00:00
abstract::Medico-legal experts are increasingly enlisted to assess the methamphetamine and amphetamine serum concentrations after a criminal offense. However, since criminal users rarely provide useful information to medico-legal experts regarding the substances abused, when the substance(s) was/were used, dose of ingestion too...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-017-1607-5
更新日期:2017-09-01 00:00:00
abstract::In the present study 161 Japanese father/son haplotype transfers in 147 pedigrees were analyzed at 14 Y-STRs with two multiplex PCR-based typing systems. Five isolated single repeat mutations were identified at the DYS389I, DYS439, Y-GATA-H4, DYS389II and DYS391 loci, and a pedigree showing triple alleles at the DYS38...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-003-0422-3
更新日期:2004-06-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The annual number of detainees held in police custody in France is approximately 700,000. Medical data regarding arrestees are scarce across countries. We present the medical characteristics of detainees kept in police custody, including addictive behaviours and high-risk medical situations. M...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-014-0990-4
更新日期:2014-09-01 00:00:00
abstract::Inferring an unknown DNA's ancestry using a set of ancestry-informative single nucleotide polymorphisms (SNPs) in forensic science is useful to provide investigative leads. This is especially true when there is no DNA database match or specified suspect. Thus, a set of SNPs with highly robust and balanced differential...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-018-1863-z
更新日期:2019-07-01 00:00:00
abstract::The goal of the present study is to examine cross-sectional information on the growth of the humerus based on the analysis of four measurements, namely, diaphyseal length, transversal diameter of the proximal (metaphyseal) end of the shaft, epicondylar breadth and vertical diameter of the head. This analysis was perfo...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-012-0713-7
更新日期:2013-01-01 00:00:00
abstract::We have studied the correlation between the level of D-aspartic acid in dentin and the period of dentin formation in different types of teeth from the same individual. Except for the third molar, it is generally agreed that the formation of permanent dentin follows the pattern of growth, occurring earliest in the firs...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-003-0365-8
更新日期:2003-06-01 00:00:00
abstract::A population database was generated from 118 unrelated Caucasoid individuals living in Spain. Sequence polymorphisms of the mitochondrial DNA (mtDNA) control region, hypervariable regions I and II (HVRI and HVRII) were determined using the polymerase chain reaction (PCR) and direct sequencing. A total of 102 different...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140000158
更新日期:2000-01-01 00:00:00
abstract::One of the most common conditions during fetal development is anencephaly, which often involves many identification difficulties in the context of physical anthropology, as it causes severe skull challenges. In this paper, we describe the alterations found in the skulls of two perinatal individuals with anencephaly fr...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-014-1123-9
更新日期:2015-07-01 00:00:00
abstract::We investigated the polymorphism of five X-chromosomal short tandem repeat markers (ChrX STRs) loci (DXS7132, DXS981, DXS6803, DXS6809, and DXS6789) and their value for forensic applications. A fluorescent multiplex polymerase chain reaction (PCR) for amplifying five ChrX STRs loci in the same PCR reaction was set up....
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-008-0223-9
更新日期:2008-05-01 00:00:00
abstract::Chumbinho is the popular name given to carbamate aldicarb (Temik), an insecticide commonly used in agriculture and highly toxic (LD50 = 0.9 mg/kg oral in rats) that has been sold clandestinely in several regions of Brazil. Chumbinho is sold illegally as raticide and is available in a formulation of small black granule...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-016-1336-1
更新日期:2016-07-01 00:00:00
abstract::We present the case of a 3.5-year-old boy with sudden anal blood loss at school. Sexual abuse was suspected, and, apart from anal fissures seen on sigmoidoscopy, no other clinical signs of any sort of disorder were present. As no medical explanation for the blood loss could be given, penetrating anal trauma was sugges...
journal_title:International journal of legal medicine
pub_type: 杂志文章,评审
doi:10.1007/s00414-005-0053-y
更新日期:2007-01-01 00:00:00
abstract::Mitragyna speciosa (Rubiaceae), commonly known as kratom, is a tropical tree with a long history of traditional use in parts of Africa and Southeast Asia. In recent years, kratom has gained popularity for use as a recreational drug across the globe. Relatively new to the illicit market and used in a manner different f...
journal_title:International journal of legal medicine
pub_type: 杂志文章,评审
doi:10.1007/s00414-015-1279-y
更新日期:2016-01-01 00:00:00
abstract::Myocardial pathology and cardiac functional abnormalities known to occur in association with chronic alcohol abuse have been attributed to a direct toxic effect of ethanol on the intra-myocardial vasculature: alcohol-induced occlusion of small arteries with consequent secondary ischaemia leads to individual myocyte lo...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01225513
更新日期:1996-01-01 00:00:00
abstract::A 49-year-old white male was found lying unconscious at home. He had vomited, his mouth was filled with a white foam and a pungent odour filled the room. After emergency treatment blood, urine and stomach contents were screened for drugs after acid and alkaline extraction with subsequent derivatisation and GC-MS analy...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050080
更新日期:1997-01-01 00:00:00
abstract::Blood, saliva, and semen are some of the forensically most relevant biological stains commonly found at crime scenes, which can often be of small size or challenging due to advanced decay. In this context, it is of great importance to possess reliable knowledge about the effects of degradation under different environm...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-016-1373-9
更新日期:2016-11-01 00:00:00
abstract::2-Amino-5-chloropyridine (ACP) is a degradation product of zopiclone (ZOP) and its two main metabolites N-desmethylzopiclone (NDZOP) and zopiclone N-oxide (ZOPNO). ACP may be formed when specimens are stored. ZOP instability in blood makes interpretation of concentrations difficult especially in cases of prolonged sam...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-014-1049-2
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:Postmortem interrogation of cardiac implantable electrical devices (CIED) in autopsy is not routinely performed. Thus, it remains unclear whether an interrogation might clarify time and cause of death. METHODS:Seventy of 4401 patients (1.6%) undergoing autopsy in 2014 and 2015 presented with a CIED. The exp...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-018-1932-3
更新日期:2019-05-01 00:00:00
abstract::In forensic science, the unequivocal identification of the cellular origin of crime scene samples used for DNA profiling can provide crucial information for crime scene reconstruction. We have previously shown that various mRNA markers from genes with expression patterns specific for blood and saliva can be establishe...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-008-0249-z
更新日期:2009-01-01 00:00:00
abstract::Postmortem MRI (PMMR) examinations are seldom performed in legal medicine due to long examination times, unfamiliarity with the technique, and high costs. Furthermore, it is difficult to obtain access to an MRI device used for patients in clinical settings to image an entire human body. An alternative is available: ex...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-014-1058-1
更新日期:2015-05-01 00:00:00